• 대한전기학회논문지:시스템및제어부문D
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• 제55권7호
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• pp.335-343
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• 2006

We have designed the system that measure one channel ECG by two electrode and extract real-time EDR with more related resipiration and comportable to subject by using conductive textile. On the assumption that relation between RL electrode and potential measurement electrode is coupled with RC connected model, we designed RL drive output to feedback two electrode for reduction of common mode signal. The conductive textile which was used for two ECG electrode was offered more comfort during night sleep in bed than any other method using attachments. In the method of single-lead EDR, R wave point or QRS interval area could be used for EDR estimation in traditional method, it is, so to speak, the amplitude modulation(AM) method for EDR. Alternatively, R-R interval could be used for frequency modulation(FM) method based on Respiratory Sinus Arrhythmia(RSA). For evaluation of performance on AM EDR and FM EDR from 14 subject, ECG lead III was measured. Each EDR was compared with both temperature around nose(direct measurement of respiration) and respiration signal from thoracic belt(indirect measurement of respiration) on mean squared error(MSE), cross correlation(Xcorr), and Coherence. The upsampling interpolation technique of multirate signal processing is applied to interpolating data instead of cubic spline interpolation. As a result, we showed the real-time EDR extraction processing to be implemented at micro-controller.

• 한국전자파학회논문지
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• 제15권12호
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• pp.1184-1189
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• 2004

본 논문에서는 직교신호를 발생할 수 있는 새로운 구조의 전압제어 발진기를 설계 제작하였다. 정확한 직교 신호 특성과 낮은 위상잡음 특성을 동시에 얻기 위하여 결합 증폭기의 source단자에 저항 궤환을 이용하여 차동 발진기를 결합시켰다. 발진기는 0.18 um 표준 CMOS 공정을 이용하여 제작하였다. 제작한 발질기의 위상잡음 특성은 -120 dBc/Hz @ 1 MHz 0$\~$1.8 V 전압을 가변하였을 때, 2.34 GHz$\~$2.55 GHz의 210 MHz 주파수 가변을 얻었다. 또한 낮은 IF 주파수 혼합기와 결합하여 측정한 결과 직교신호의 위상 오차는 0.5도, 진폭 오차는 0.2 dB 이하를 보였다. 바이어스 전류는 1.8 V 공급전압에 대해 전압제어발진기의 Core 부분 5 mA를 포함하여 전체적으로는 19 mA를 요구한다.

• 한국생산제조학회지
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• 제20권1호
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• pp.47-52
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• 2011

It is well known that stiffness of composites depends on layup sequence of CFRP(carbon fiber reinforced plastics) laminates because the layup of composite laminates influences their properties. Ultrasonic NDE of composite laminates is often based on the backwall echoes of the sample. A pair of such transducers was mounted in a holder in a nose-to-nose fashion to be used as a scanning probe on composites. Miniature potted angle beam transducers were used (Rayleigh waves in steel) on solid laminates of composites. Experiments were performed to understand the behavior of the transducers and the nature of the waves generated in the composite (mode, wave speed, angle of refraction). C-scan images of flaws and impact damage were then produced by combining the pitch-catch probe with a portable manual scanner known as the Generic Scanner ("GenScan"). The pitch-catch signal was found to be more sensitive than normal incidence backwall echo of longitudinal wave to fiber orientation of the CFRP composites, including low level porosity, ply waviness, and cracks. Therefore, it is found that the experimentally Rayleigh wave variation of pitch-catch ultrasonic signal was consistent with numerical results and one-side ultrasonic measurement might be very useful to detect the defects.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.112-112
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• 2003

Voltage-gated $K^{+}$ (Kv) channels represent a structurally and functionally diverse group of membrane proteins. These channels play an important role in determining the length of the cardiac action potential and are the targets for antiarrhythmic drugs. Many $K^{+}$ channel genes have been cloned from human myocardium and functionally contribute to its electrical activity. One of these channels, Kv1.5, is one of the more cardiovascular-specific $K^{+}$ channel isoforms identified to date and forms the molecular basis for an ultra-rapid delayed rectifier $K^{＋}$ current found in human atrium. Thus, the blocker of hKv1.5 is expected to be an ideal antiarrhythmic drug for atrial fibrillation. Chelidonine was isolated from Chelidonium majus L. We examined the effect of chelidonine on the hKv1.5 current expressed in Ltk-cells using whole cell mode of patch clamp techniques. Chelidonine selectively inhibited the hKv1.5 current expressed in Ltk-cells in a concentration-dependent manner, whereas did not affect the HERG current expressed in HEK-293 cells. Additionally, chelidonine reduced the tail current amplitude recorded at -50 mV after 250 ms depolarizing pulses to +60 mV, and slowed the deactivation time course resulting in a 'crossover' phenomenon when the tail currents recorded under control conditions and in the presence of chelidonine were superimposed. We found that chelidonine also inhibited the $K^{+}$ current in isolated human atrial myocytes where hKv1.5 channels were predominantly expressed. Furthermore, we examined the effects of chelidonine on the action potentials in rabbit hearts using conventional microelectrode technique. Chelidonine prolonged the action potential durations (APD) of atrial, ventricular myocytes and Purkinje fibers in a dose-dependent manner. However, the effect of chelidonine on atrial APD was frequency-dependent whereas the effect of chelidonine on the APDs of ventricular myocytes and Purkinje fibers was not frequency- dependent. Also, the selective action of chelidonine on heart was more potent than dofetilide, $K^{+}$ channel blocker.

• Natural Product Sciences
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• 제19권4호
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• pp.290-296
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• 2013

In preliminary tests, we examined the effect of several fractions isolated from fermented pine needle extract on pacemaker potentials in cultured interstitial cells of Cajal (ICCs) from the mouse colon using a whole cell patch clamp technique. Among these fractions, Fraction 3 (F3) elicited the most powerful depolarization of membrane. Therefore, the aim of the present study was to investigate the effect of F3 obtained from fermented extract of Pinus densiflora needle on pacemaker potentials in ICCs and to establish its mechanism of action. Colonic ICCs generated spontaneous periodic pacemaker potentials in the current-clamp mode. F3 depolarized the membrane and decreased the frequency and amplitude of pacemaker potentials in a dose-dependent fashion. The F3-induced effects on pacemaker potentials were blocked by methoctramine, a muscarinic $M_2$ receptor antagonist, and by glycopyrrolate, a muscarinic $M_3$ receptor antagonist. The F3-induced effects on pacemaker potentials were blocked by external $Na^+$-free solution and by flufenamic acid, a non-selective cation channel blocker, as well as by the removal of external $Ca^{2+}$ and in the presence of thapsigargin, a $Ca^{2+}$-ATPase inhibitor in the endoplasmic reticulum. Taken together, these results suggest that F3 of pine needle extract modulates the pacemaker activity of colonic ICCs by the activation of non-selective cation channels via muscarinic $M_2$ and $M_3$ receptors. And external $Ca^{2+}$ influx and intracellular $Ca^{2+}$ release are involved in F3 actions on ICCs.

• 한국수소및신에너지학회논문집
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• 제22권4호
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• pp.552-558
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• 2011

A 50 kW class rotating body type wave energy converter consisted of two floating bodies and a PTO (Power Takeoff) unit is studied. As an wave energy extractor, the body is designed to have a VLCO (Variable Liquid-Column Oscillator) having a liquid filled U-tube with air chambers. Owing to the oscillation of the liquid in the U-tube caused by the air spring effect of the air chambers, the amplitude of response of the VLCO becomes significantly amplified for a target wave period. The PTO converts the rotational moment introduced from the relative motion of the hinged bodies to an hydraulic power by means of a cylinder. A high pressure accumulator, hydraulic motor and a generator are equipped in the PTO to convert the hydraulic power to electric power. A control law for adjusting the oscillation period of the VLCO is proposed for the efficient operation of the VLCO with various wave conditions. It is found that the effect of the air spring has an important role to play in making the oscillation of the VLCO match with the ocean wave. In this way, the wave energy converter equipped with the VLCO provides the most effective mode for extracting energy from the ocean wave.

• 대한기계학회논문집B
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• 제25권10호
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• pp.1327-1336
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• 2001

The structural modes driven by the low wave-number components of smooth elastic wall pressure provide a relatively weak coupling between the flow and the wall motion. If the elastic thin plate has any resonant mode whose wave-number of resonance coincides with $\omega$/U$\sub$c/, the power will be transmitted to those modes of vibration by the flows. We examine the problem in which the elastic thin plate is subject to pressure fluctuations under turbulent boundary layer. Measurements are presented of the frequency spectra of the near- and far-field pressures and radiated sound contributed by the various wave modes of the thin elastic plate. Dispersion equation for wave motions of elastic plate is used to investigate the effect of bending waves of relatively low wave number on radiated sound. The low wave-number motion of elastic plate is observed to have much less influence on the low-frequency energy of wall pressure fluctuations than that of the rediated sound. High amplitude events of the wall pressure are observed to weakly couple with high-frequency energy of radiated sound for case of low tension applied to the plate. The sound source localization is applied to the measurement of radiated sound by using acoustic mirror system.

• 전력전자학회논문지
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• 제6권2호
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• pp.125-131
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• 2001

본 논문은 백터제어기법을 적용한 철도차량용 1.2MVA전동차 구동시스템의 개발에 관한 것이다. 벡터제어를 위해서는 출력 전압의 크기와 위상을 순시적으로 제어해야한다. 전동차 구동시스템에서는 DC링크 단의 전압 이용률을 최대로 하기 위해 고속 운전 영역에서는 1펄스 모드를 사용한다. 따라서 고속 운전 영역에서는 토크성분 전류와 지송성분 전류를 독립적으로 술시 에어해야 하는 백터제어기법을 정용할 수 없다. 이에, 본 연구에서는 저속이 운전영역에서는 순시 토크 제어가 가능한 벡터제어를 적용하고, 고속 운전 영역에서는 슬립 주파수제어를 적용하는, 백터 제어와 스칼라 제어의 병용제어 기법을 제안하였다. 또한 운전영역에 따라 이들 두 제어방법이 부드럽게 전환되도록 하는 제어기법이 제시되었다. 제안되 제어기법을 4대의 210kW 유도전동기를 구동하는 1.2MVA 전동차 견인 구동시스템에 적용하여 그 효용성을 알아보았다.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 1998년도 추계학술발표 논문집
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• pp.143-147
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• 1998

Autonomic and EEG responses of 38 college students were studied during 60-sec long presentation of International Affective Picture System (IAPS )slides evoking, according to subjective reports, negative (disgust, sadness, surprise) and positive (happiness, exciting) emotional. states. Observed were significant heart rate (HR) deceleration, large skin conductance responses (SCR), moderate respiration frequency slowing, reduction of frontal (F 3, F 4 ) and occipital (O 1, O 2 ) fast alpha, and increases of theta, delta and beta relative spectral power values during the first 30 sec of exposure of IAPS pictures. Analysis carried out to differentiate emotion categories according to autonomic responses indicated that observed HR deceleration was larger in magnitude in surprise and sadness than in disgust, SCR amplitude higher in sadness than in disgust. EEC showed significant differences in theta (F 3, F 4 ) and delta (O 1) power increase in disgust vs. happiness, fast alpha (F 3, F 4 ) power was lower in surprise than in happiness, and slow beta power higher. in happiness than in disgust (0 1). Despite some differences. observed within discrete emotion conditions, overall responses pattern of monitored parameters exhibited similar profiles with few variations, most. obvious. in disgust state, which suggests that affective visual stimulation elicits stereotypical responses in a given passive viewing paradigm. However, the magnitude of physiological responses may vary to certain extent across discrete emotional states making it possible to differentiate among particular experimentally-induced emotional states, e.g., disgust vs. sadness by ANS responses or disgust vs. happiness by EEG measures.

• 비파괴검사학회지
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• 제13권3호
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• pp.7-13
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• 1993

AISI 4130 금속재를 사용한 균열 컴팩터 인장시편의 파괴거동이 음향방출(AE) 및 초음파 C-scan을 이용하여 조사되었다. 모든 시편들을 특정 수준의 하중까지 증가시키면서, 크랙 개구변위 (COD)와 더불어 여러가지의 음향방출 인자들을 얻었다. 크랙 선단의 크랙 개구변위와 손상(소성)역을 계산하기 위하여 탄소성 유한요소 해석이 수행되었다. 펄스-반사, 침수형으로한 초음파 C-scan은 손상역 크기와 상사시키기 위하여 행해졌다. 유한요소 해석 결과와 측정된 크랙개구변위는 만족할 정도로 일치하였다. 음향방출 결과에서, 시험시편들은 연성거동을 나타내었다. 총 사상수대 크랙 개구변위의 기울기는 크랙 개시점을 결정하는 데에 유용하였다. 예비 시험적인 C-scan 화상은 손상역의 초음파 진폭변화를 보여주었고, 손상역의 형상 및 크기가 유한요소 결과와 정성적으로 부합되었다. 손상역 크기에 관한 추가적인 연구가 요약되었다.