Journal of the Korea Institute of Military Science and Technology
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v.11
no.4
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pp.36-45
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2008
LYNX ESM system operates digital receiver for analyzing radar of intrapulse modulation signal. This paper contains DC offset compensation method of IQ channels, imbalancing comensation method of amplitude and phase, precisional PW measurement using adaptive threshold set, analyzing algorithm of intrapulse modulation signals. Its effectiveness was proven by technical and operational test.
The present study was aimed at investigating whether the calcium current in the vascular smooth muscle (VSM) cells is altered in renal hypertension. Two-kidney, one clip (2K1C) and deoxycorticosterone acetate (DOCA)-salt hypertension were made in Sprague-Dawley rats. Rats without clipping the renal artery or implanting DOCA were used as control for 2K1C and DOCA-salt hypertension, respectively. Four weeks after clipping, systolic blood pressure was significantly higher in 2K1C rats than in control $(192{\pm}24\;and\;119{\pm}4$ mmHg, respectively, n=16 each). DOCA-salt rats also showed a higher blood pressure $(180{\pm}15$ mmHg, n=18) compared with control $(121{\pm}6$ mmHg, n=14). VSM cells were enzymatically and mechanically isolated from basilar arteries. Single relaxed VSM cells measured $5{\sim}10\;{\mu}m$ in width and $70{\sim}150\;{\mu}m$ in length were obtained. VSM cells could not be differentiated in size and shape between hypertensive and normotensive rats under light microscopy. High-threshold (L-type) calcium currents were recorded using whole-cell patch clamp technique. The amplitude of the current recorded from VSM cells was larger in 2K1C hypertension than in control. Neither the voltage-dependence of the calcium current nor the cell capacitance was significantly affected by 2K1C hypertension. By contrast, the amplitude of the calcium current was not altered in DOCA-salt hypertension. These results suggest that high-threshold calcium current of the VSM cells is altered in 2K1C hypertension, and that calcium channel may not be involved in calcium recruitment of VSM in DOCA-salt hypertension.
An, Hwi;Shim, Hyoung-Jin;Park, Jae-Soon;Lhm, Jong-Tae;Joung, Yeun-Ho
Journal of Biomedical Engineering Research
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v.43
no.4
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pp.280-289
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2022
In this paper, we present a QRS-complex detection algorithm to calculate an accurate heartbeat and clearly recognize irregular rhythm from ECG signals. The conventional Pan-Tompkins algorithm brings false QRS detection in the derivative when QRS and noise signals have similar instant variation. The proposed algorithm uses amplitude differences in 7 adjacent samples to detect QRS-complex which has the highest amplitude variation. The calculated amplitude is cubed to dominate QRS-complex and the moving average method is applied to diminish the noise signal's amplitude. Finally, a decision rule with a threshold value is applied to detect accurate QRS-complex. The calculated signals with Pan-Tompkins and proposed algorithms were compared by signal-to-noise ratio to evaluate the noise reduction degree. QRS-complex detection performance was confirmed by sensitivity and the positive predictive value(PPV). Normal ECG, muscle noise ECG, PVC, and atrial fibrillation signals were achieved which were measured from an ECG simulator. The signal-to-noise ratio difference between Pan-Tompkins and the proposed algorithm were 8.1, 8.5, 9.6, and 4.7, respectively. All ratio of the proposed algorithm is higher than the Pan-Tompkins values. It indicates that the proposed algorithm is more robust to noise than the Pan-Tompkins algorithm. The Pan-Tompkins algorithm and the proposed algorithm showed similar sensitivity and PPV at most waveforms. However, with a noisy atrial fibrillation signal, the PPV for QRS-complex has different values, 42% for the Pan-Tompkins algorithm and 100% for the proposed algorithm. It means that the proposed algorithm has superiority for QRS-complex detection in a noisy environment.
Retinal prosthesis is regarded as the most feasible method for the blind caused by retinal diseases such as retinitis pigmentosa (RP) or age related macular degeneration (AMD). Recently Korean consortium launched for developing retinal prosthesis. One of the prerequisites for the success of retinal prosthesis is the optimization of the electrical stimuli applied through the prosthesis. Since electrical characteristics of degenerate retina are expected to differ from those of normal retina, we performed voltage stimulation experiment both in normal and degenerate retina to provide a guideline for the optimization of electrical stimulation for the upcoming prosthesis. After isolation of retina, retinal patch was attached with the ganglion cell side facing the surface of microelectrode arrays (MEA). $8{\times}8$ grid layout MEA (electrode diameter: $30{\mu}m$, electrode spacing: $200{\mu}m$, and impedance: $50k{\Omega}$ at 1 kHz) was used to record in-vitro retinal ganglion cell activity. Mono-polar electrical stimulation was applied through one of the 60 MEA channel, and the remaining channels were used for recording. The electrical stimulus was a constant voltage, charge-balanced biphasic, anodic-first square wave pulse without interphase delay, and 50 trains of pulse was applied with a period of 2 sec. Different electrical stimuli were applied. First, pulse amplitude was varied (voltage: $0.5{\sim}3.0V$). Second, pulse duration was varied $(100{\sim}1,200{\mu}s)$. Evoked responses were analyzed by PSTH from averaged data with 50 trials. Charge density was calculated with Ohm's and Coulomb's law. In normal retina, by varying the pulse amplitude from 0.5 to 3V with fixed duration of $500{\mu}s$, the threshold level for reliable ganglion cell response was found at 1.5V. The calculated threshold of charge density was $2.123mC/cm^2$. By varying the pulse duration from 100 to $1,200{\mu}s$ with fixed amplitude of 2V, the threshold level was found at $300{\mu}s$. The calculated threhold of charge density was $1.698mC/cm^2$. Even after the block of ON-pathway with L-(1)-2-amino-4-phosphonobutyric acid (APB), electrical stimulus evoked ganglion cell activities. In this APB-induced degenerate retina, by varying the pulse duration from 100 to $1200{\mu}s$ with fixed voltage of 2 V, the threshold level was found at $300{\mu}s$, which is the same with normal retina. More experiment with APB-induced degenerate retina is needed to make a clear comparison of threshold of charge density between normal and degenerate retina.
The stability of the steady Rossby-Haurwitz wave (R-H wave) in the nondivergent barotropic model (NBM) on the sphere was investigated with the normal mode method. The linearized NBM equation with respect to the R-H wave was formulated into the eigenvalue-eigenvector problem consisting of the huge sparse matrix by expanding the variables with the spherical harmonic functions. It was shown that the definite threshold R-H wave amplitude for instability could be obtained by the normal mode method. It was revealed that some unstable modes were stationary, which tend to amplify without the time change of the spatial structure. The maximum growth rate of the most unstable mode turned out to be in almost linear proportion to the R-H wave amplitude. As a whole, the growth rate of the unstable mode was found to increase with the zonal- and total-wavenumber. The most unstable mode turned out to consist of more-than-one zonal wavenumber, and in some cases, the mode exhibited a discontinuity over the local domain of weak or vanishing flow. The normal mode method developed here could be readily extended to the basic state comprised of multiple zonalwavenumber components as far as the same total wavenumber is given.
IEMEK Journal of Embedded Systems and Applications
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v.11
no.5
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pp.277-285
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2016
Moving object detection system has been an emerging research field in various advanced driver assistance systems (ADAS) and surveillance system. In this paper, we propose two optical flow based moving object detection methods at dynamic scenes. Both proposed methods consist of three successive steps; pre-processing, foreground segmentation, and post-processing steps. Two proposed methods have the same pre-processing and post-processing steps, but different foreground segmentation step. Pre-processing calculates mainly optical flow map of which each pixel has the amplitude of motion vector. Dense optical flows are estimated by using Farneback technique, and the amplitude of the motion normalized into the range from 0 to 255 is assigned to each pixel of optical flow map. In the foreground segmentation step, moving object and background are classified by using the optical flow map. Here, we proposed two algorithms. One is Gaussian mixture model (GMM) based background subtraction, which is applied on optical map. Another is adaptive thresholding based foreground segmentation, which classifies each pixel into object and background by updating threshold value column by column. Through the simulations, we show that both optical flow based methods can achieve good enough object detection performances in dynamic scenes.
Journal of the Korean Institute of Electrical and Electronic Material Engineers
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v.33
no.2
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pp.93-98
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2020
We investigated the effect of a post-annealing process using ultraviolet (UV) light on the electrical properties of solution-processed InZnO (IZO) thin-film transistors (TFTs). UV light was irradiated on IZO TFTs for different time periods of 0s, 30s, and 90s. We measured transfer and retention stability curves to evaluate the performance of the fabricated TFTs. In addition, we measured height, amplitude, and phase AFM images to analyze changes in the surface and morphology of the devices. AFM measurements were performed by setting the drive amplitude of the cantilever tip to 47.9 mV in tapping mode, then dividing the device surface into 500 nm × 500 nm. In the case of IZO TFT irradiated with UV for 30s, the electron mobility and Ion/Ioff ratio were improved, the threshold voltage was reduced by approximately 2 V, and the subthreshold swing also decreased form 1.34 V/dec to 1.11 V/dec.
In order to examine the effect of anisotropy and stress ratio on fatigue crack propagation rate and opening-closing behavior and also arrest behavior by single tension peak overload, the fatigue tests of constant amplitude atress and single tension peak overload adding to cycle of constant amplitude were carried out in stress ratio of -0.4, -0.2, and 0.4 with materials of T-L and L-T directions in 2024-T3 aluminum alloy plate. Crack opening-closing begavior were measured by the compliance method using COD gage and strain gage. In case of the crack opening-closing behavior was measured by strain gage, the effect of stress ratio is unchangeable. But in the case of COD gage, that is remarkably decreased. Fictitious effective stress intensity factor(U sub(f)) and effective stress intensity factor ratio(U) in L-T direction was higher than those in T-L direction and also threshold arrest overload ratio incrased as stress ratio decreased and that of T-L direction was higher than that in L-T direction.
Dysfunction of the inferior alveolar nerve may result from trauma, diseases or iatrogenic injury. The development and refinement of an objective method to evaluate this clinical problem is highly desirable and needed, especially concerning for an increasing medico-legal issue. Evoked potential techniques have attracted considerable attention as a means of assessing the function and integrity of nerve pathways. The purpose of this study was to characterize the Sensory Evoked Potentials(SEPs) and Somatosensory Evoked Potentials(SSEPs) elicited by electrical stimulation of mental nerve. SEPs and SSEPs were measured and analyzed statistically before and after needle injury on the inferior alveolar nerve of Sprague-Dawalye rats. Measuring SEPs was more sensitive in evaluation of the recovery of sensory function from inferior alveolar nerve injury then measuring SSEPs but we measured SSEPs in the hope of providing a safe, simple and objective test to check oral and facial sensibility, which is acceptable to the patient. We stimulated mental nerve after needle injury on the inferior alveolar nerve and SEPS on the level of mandibular foramen and SSEPs on the level of cerebral cortex were recorded. Threshold, amplitude, and latency of both of SEPs and SSEPs were analyzed. The results were as follows ; 1. Threshold of SEPs and SSEPs were $184{\pm}14{\mu}A$ and $164{\pm}14{\mu}A$ respectively. 2 SEPs were composed of 2 waves, i.e., N1 N2 in which N1 was conducted by II fibers and N2 was conducted by III fibers. 3. SSEPS were composed of 5 waves, of which N1 and N2 shower statistically significant changes(p<0.01, unpaired t-test). 4. SEPs and SSEPs were observed to be abolished immediately after local anesthesia and recovered 30 minutes later. 5. SEPs were abolished immediately after injury. N1 of SSEPs was abolished immediately and amplitued of N2 was decreased($20.7{\pm}12.2%$) immediately after 23G needle injury, but N3, N4 and N5 did not change significantly. Recovery of waveform delayed 30 minutes in SEPs and 45 minutes in SSEPs. 6. The degree of decrease in amplitude of SEPs and SSEPs, after 30G needle injury was smaller than those with 23G. SEPs recorded on the level of mandibular foramen were though to be reliable and useful in the assessment of the function of the inferior alveolar nerve after injury. Amplitude of SSEPs reflected the function and integrity of nerve and measuring them provided a safe, simple and abjective test to check oral and facial sensibility. These results suggest that measuring SEPs and SSEPs are meaningful methods for objective assessment in the diagnosis of nerve injury. N1 and N2 of SSEPs can be useful parameters for the evaluation of the nerve function following a needle injury.
Journal of rehabilitation welfare engineering & assistive technology
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v.8
no.2
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pp.95-99
/
2014
Binaural interaction can recognize the same intensity sound by stimulating two ears alternatively, and it can be record auditory brainstem responses (ABR). However, We needs to be researched about binaural interaction in asymmetric binaural acoustic stimulation. 17 normal young hearing university students were participated. Clicks were presented at the intensity of 90 dB nHL to one ear and the click intensity was increased from 0 to 90 dB nHL with a separation of 10 dB to another ear, simultaneous. BI waveform was obtained by subtracting the sum of the asymmetrically evoked potentials from the binaurally evoked potentials; i.e. BI = B - (L + R). Latency and amplitude was measured 'peak to following trough' of IV-V complex of BI waveform. Threshold of BIC (t-BIC) was obtained using amplitude depend on stimulus intensities (paired sample t-test). Latency shifted in 4.65, 4.63, 4.57, 4.58, 4.62, 4.6, 4.48, 4.36, 4.23 ms for peak, 5.57, 5.51, 5.51, 5.59, 5.61, 5.55, 5.44, 5.28, 5.19 ms for trough, and amplitude shifted in .0.32, -0.3, -0.34, -0.32, -0.42, -0.53, -0.54, -0.61, $-0.67{\mu}V$ from 0 to 90 dB nHL in every 10 dB, respectively. t-BIC was observed 40 dB nHL(p=.001).
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