• Asian Pacific Journal of Cancer Prevention
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• 제17권1호
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• pp.369-372
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• 2016

Background: Acute myeloid leukemia is an acquired clonal heterogeneous stem cell disorder. Hence, various parameters are sought out to categorize this disease into subtypes, so that as a consequence specific treatment modalities can be offered. Conventionally, the practically used method for classification utilizes French American British (FAB) criteria based on morphology and cytochemistry. The aim of present study was to determine the current spectrum of AML sub types in patients in Karachi. Materials and Methods: This single centre cross sectional study was conducted at Liaquat National Hospital, Karachi, extending from January 2010 to December 2014. Data were retrieved from archives were analyzed with SPSS version 22. Results: A total of 125 patients were diagnosed at our institution with de novo AML during five years period, 76 males and 49 females. Median age was 34.5 years. AML-M1 was the predominant FAB subtype (23.2%) followed by M2 (18.4%), M3 and M4 (16% each), M0 (14.4%), M5 (7.2%), M6 (3.2%) and M7 (1.6%). Conclusions: AML in Pakistani patients is seen in a relatively young population. The most common FAB subtype observed in our study was acute myeloblastic leukemia, without maturation (M1).

• 디자인학연구
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• 제11권
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• pp.1-9
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• 1995

스칸디나비아의 디자인은 디자인 역사에서 독특한 위치를 차지하고 있다. 특히 스웨덴은 스칸디나비아 국가들 중 가장 먼저 그들만의 고유한 20세기 디자인운동과 양식을 발전시킨 나라였다. '스웨디쉬 모던(Swedigh Modern)', '스웨디쉬 그레이스(Swedish Grace)'등의 개념으로 특징지어지는 스웨덴의 디자인은 20세기 초 독립에서 시작된 기능주의 운동을 받아들여 보다 우아하고 따뜻한 인간미 넘치는 디자인 양식을 만들어 내었다. 휴머니즘과 함께 단순성, 아름다움, 민주주의 적 이상이 조화된 이 양식은 국제적으로도 큰 성공을 거두어 유럽뿐 아니라 미국의 디자인 발전에도 큰 영향을 미쳤다. 본 연구에서는 스웨덴 디자인이 발전되어온 과정과 스웨덴의 디자인 교육, 기업체에서의 디자인 등을 통해 스웨덴 디자인의 특성이 과연 무엇이고 그것은 또 어디에서 비롯되는 것인지에 대해 살펴보고자 한다.

• 디자인학연구
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• 제15권1호
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• pp.81-92
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• 2002

Through network draft, it′s possible to describe curve draft with main motive in a lobby loom and to fulfill draft design more conveniently thanks to the development of computer device. Network draft was introduced by Alice Schlein, who is an American weaving artist, and I had ever published research paper on "The unfolding and development of network draft using computer dobby system" . The purpose of the next study was to develop the design of network draft while do make a design network draft in a dobby loom with 16 shafts, and could reach follow conclusion as a result of designing a variety of drafts. The initial of 4-end in a loom with 16 shafts was a basic condition to describe more perfect shape in comparison with draft in 8 shafts through the development of network. The development of draft line was essential to deride the pattern of fabric, and the pattern of draft is decided according to selecting key peg plan. Thereby, could get a variety of draft patterns derive from mix key peg plan with initial selected by developing the kind of draft line and applying diverse key peg plan. As for the variation and diversification of draft line, the shape of patters varied depending col the curve extent and connectivity of draft line and the size of curve. The pattern of network draft can be changed infinitely by free round curve of draft line. In addition, a variety of draft designs shall be developed by increasing the number of shaft, enlarging the scale of draft line, and developing more creative draft line.

• Archives of Pharmacal Research
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• 제23권4호
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• pp.418-423
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• 2000

Oka strain VR-795 (Varicella Zoster Virus, VZV) of American Type Culture Collection (ATCC) has been used for chickenpox vaccine production. In order to use this strain for vaccine production, the strain must be identified and its stability must be confirmed. The identification of the Oka strain has been confirmed using Restriction Fragment Length Polymorphism (RFLP) and DNA sequence analysis of glycoprotein-II (gp-II). The amino acid sequences of Oka deduced from the DNA sequence of gp-II have changed at three amino acids against Ellen and at one amino acid against Webster. To prove the stability of the Oka strain during the passage, RFLP and DNA sequence analyses were also used with 11, 15 and 23 times of virus passage. We found that the Oka strain was stable at passages of up to 23 times, based on the RFLP and DNA sequence analyses. The confirmed Oka strain was renamed as BR-Oka for the purposes of chickenpox vaccine production.

• 기록학연구
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• 제8호
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• pp.181-211
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• 2003

The purpose of this study is to reveal the context within which EAD was developed, to review the elements and the structure of EAD 1.0 version and to introduce EAD as new standard for encoded archival finding aids in Korea. Encoded Archival Description(EAD) has been developed in 1993 in order to facilitate exchange of ISAD(G) descriptive information. EAD is currently administered and maintained jointly by the Society of American Archivists and the United States Library of Congress. While development was initiated in the United Stares, international interest and contribution are increasing. EAD is a encoding standard designed specifically for marking up information contained in archival finding aids. From its inception, EAD was based on SGML, and, with the release of EAD version 1.0 in 1998, it is also compliant with XML in order to facilitate easier internet access to SGML-encoded finding aids. EAD is the first tool to preserve the multilevel and hierarchical description manifest in finding aids by providing structures in which to describe entire record collections and increasingly smaller subcomponents thereof such as series, subseries, folders, and even items. Archival institutions can form a EAD consortium and also create a union database of EAD finding aids for the geographically dispersed collections. The EAD DTD provides a flexible way for archives to convert finding aids that exist in paper form into electronic documents or to create new finding aids in electronic form.

• 디자인학연구
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• 제13권
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• pp.177-200
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• 1996

The purpose of this study is to show the textile designers how to be creative and how to accept other ideas which are not necessarily of their own, and to show what exactly creating anything means. During the 1950's and'60s. America and Europe reached their peak in developing their consumption culture. After World War II, America achieved an astonished feat in developing its thechnology and industry to cause the economy to a rapid ascendence. The U.S. government adopted the Keynsian theory in its economic policy. The Keynsian theory advocates the consumer spending. And during this time period the American public developed consumption habit. Mass production and mass media went in hand to induce the public to buy. The public became an important target for the advertising stratages of the industry. In order for the industry to advertise the mass produced products, it had to utilize the mass media such as television, newspaper, and magazine. And mass media came into play an important role not to advertise the products, but to imform and educate the public about the products. This corporate stratege is further enhanced by the desire of the American public to climb up the ladder by way of material possession. Pop Art was born not only in reflecting the ideology of the consumption culture, but acted as a catalyst for more spending. The subjects of Pop Art are cars, foods, comics, Hollywood actors and movie scenes, the famous singers or persons. Andy Warhol specifically used the chosen image repeatedly to emphasize the redundacy of the image. The common factors which exist between Andy Warhol's Pop Art and textile design is the repetition in form, and the way of transferring an image to a canvas - Warhol used the frotttage technique to transfer an image to a canvas and textile design is transferred to a paper by way of transferring technique. Also the way Warhol thought of his paintings as a decorative elements and made a couple of his paintings into wallpapers or exhibits his painstings wall to wall demonstrates his close alliance with the textile design, let alone his comercial design background. In this study, I examined the inter-relationship between textile design and Pop Art. To carry out this study, I examined the comsumption culture: and the biomorphic relationship of culture and art: and Pop art and its transience stage. The major finding of this study is there exists a common denomenator between textile design and Pop Art, especially of Andy Warhol's.

• 디자인학연구
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• 제16권2호
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• pp.161-170
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• 2003

20세기 말부터 급격한 발달을 통하여 웹사이트는 사용자의 대상 범주를 단일 문화권에서 벗어나 전세계의 타 문화권에 거주하는 사람들에게 이르기까지 넓혀왔다. 이는 다시 말하면 웹사이트가 태생적으로 문화와의 연관성을 가지고 있다는 것을 의미한다. 이러한 다국적 문화 수용체로서의 웹의 역할을 생각하여 볼 때, 서로 다른 문화권에서 웹사이트가 어떠한 형태로 변환되어 적용되어야 하는가를 보다 심층적으로 밝혀내고자 한다. 본 연구에서는 웹사이트의 구조가 각기 다른 문화권의 영향에 따라서 변화한다는 가설을 바탕으로 그 진위여부를 밝히는 것을 그 목적으로 하였으며, 이를 위하여 다음과 같은 실험을 진행하였다. 우선 여러 가지 문화이론을 기반으로, 현재 IT산업의 활발한 발달 모습을 보이고 있는 한국과 미국의 웹사이트가 그 문화적인 차이로 인하여 어떻게 다른 양상을 띄고 있는지를 웹사이트의 구조(Structure & Navigation)를 중심으로 분석하였다. 우선 각 국가별 20여 개의 종합쇼핑몰(I-commerce) 사이트들을 분석하기 위하여, 종합쇼핑몰 평가가이드라인 (I-commerce Site Evaluation Guideline)을 사이트 정보의 흐름과 페이지 별 분석으로 나누어 제안하고, 이를 이용하여 비교 분석한 결과를 바탕으로 문화권에 따른 국가별 선호 프로토타입(prototype)을 디자인하였으며, 이렇게 제안된 국가별 선호 프로토타입을 이용하여 원격 사용성 평가와 문화적 가치에 관한 설문을 통하여 국가별 웹사이트의 구조 선호도에 관한 가설의 진위 여부를 밝혀 내었다. 또한 이에 문화와 웹 인터페이스와의 연관성 및 국가별 사이트 네비게이션의 선호도에 대한 결과를 다양한 문화 이론을 바탕으로 해석해 내었다. 조직의 강도(

• Archives of Plastic Surgery
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• 제33권3호
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• pp.289-293
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• 2006

By means of microsurgical free-tissue transfer providing a large amount of required tissue, the surgeon can resect tumoral tissue more safely, which allows tumor-free margins and enhances the reliability of the ablative surgery that otherwise could not be performed radically. The morbidity of elective free-tissue transfer seems to be quite low, carrying acceptable risks for most patients. But the elderly patients are at risk for cardiac and respiratory problems, deep vein thrombosis, pulmonary emboli and infection merely as a function of age. This study was undertaken to define further risks of the elderly population with regards to free-tissue transfer. We retrospectively reviewed our experience with 110 microsurgical free-tissue transfers for head and neck reconstruction in patients greater than 60 years of age. Microsurgical procedures in all cases were preformed by the plastic and reconstructive department at Yonsei medical center. The investigated parameters were patient demographics, past medical history, American Society of Anesthesiologists(ASA) status, site and cause of defect, the free tissue transferred and postoperative complication including free-flap success or failure. There were 46 patients in the age group from 60 to 64 years, 34 patients from 65 to 70 years, and 30 patients 70 years or older. There happened 3 flap losses, resulting in a flap viability rate of 97%. Patients with a higher ASA designation experienced more medical complication(p=0.05, 0.01, 0.03 in each age group I, II, III) but not surgical complication p=0.17, 0.11, 0.54 in each age group I, II, III). And the relationship between postoperative complication and age groups was not significant. These observations suggest that major determinant for postoperative medical complication be the patient's American Society of Anesthesiologists score, and chronologic age alone should not be an exclusion criterion when selecting patients for free-tissue transfer

• Archives of Plastic Surgery
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• 제46권4호
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• pp.336-343
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• 2019

Background Sternal rigid plate fixation (RPF) has been adopted in recent years in high-risk cases to reduce complications associated with steel wire cerclage, the traditional approach to sternal closure. While sternal RPF has been associated with lower complication rates than wire cerclage, it has its own complication profile that requires evaluation, necessitating a critical examination from a national perspective. This study will report the outcomes and associated risk factors of sternal RPF using a national database. Methods Patients undergoing sternal RPF from 2005 to 2016 in the American College of Surgeons-National Surgical Quality Improvement Program were identified. Demographics, perioperative information, and complication rates were reviewed. Logistic regression analysis was performed to identify risk factors for postoperative complications. Results There were 381 patient cases of RPF identified. The most common complications included bleeding (28.9%), mechanical ventilation >48 hours (16.5%), and reoperation/readmission (15.2%). Top risk factors for complications included dyspnea (odds ratio [OR], 2.672; P<0.001), nonelective procedure (OR, 2.164; P=0.010), congestive heart failure (OR, 2.152; P=0.048), open wound (OR, 1.977; P=0.024), and operating time (OR, 1.005; P<0.001). Conclusions Sternal RPF is associated with increased rates of three primary complications: blood loss requiring transfusion, ventilation >48 hours, and reoperation/readmission, each of which affected over 15% of the study population. Smokers remain at an increased risk for surgical site infection and sternal dehiscence despite RPF's purported benefit to minimize these outcomes. Complications of primary versus delayed sternal RPF are roughly equivalent, but individual patients may perform better with one versus the other based on identified risk factors.

• 한국도서관정보학회지
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• 제40권3호
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• pp.271-293
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• 2009

기록관리 전문가는 업무의 특성에 따라 학문적지식과 실무능력을 갖추어야 한다. 특히 기록관은 정보기술의 발달에 따라 계속하여 변화하고 있어 폭넓은 실습을 통한 기술적인 전문성이 있는 실무능력을 갖춘 기록관리 전문가를 요구하고 있다. 그러나 현재 국내 기록관리 대학원들의 교육과정은 이론교육에 치중되어 있어 실무교육이 미흡한 실정이다. 따라서 본 논문은 미국과 한국의 대학원 기록관리 교육과정에서 실무능력 향상을 위한 요소의 현황을 비교 분석하여 한국 기록학 대학원의 교육과정을 이론적인 지식은 물론 실제적인 업무능력을 배양할 수 있는 방안을 제언하였다. 첫째, 한국의 기록학 교육과정 중 실무영역을 강화를 위해 전공학점의 및 이수학점의 증대, 실습을 필수 교과과정으로 할 것을 제언하였다. 둘째, 내실 있는 실습을 위한 관 학 산 협동의 인턴쉽 프로그램의 개발 및 실시를 제언하였다. 셋째, 현재 기록관리 업무에 종사하고 있는 기록관리 전문가들이 새로운 지식과 기술을 습득하여 그 전문성을 제고할 수 있는 계속교육프로그램을 실시할 것을 제언하였다.