• 한국주거학회:학술대회논문집
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• 한국주거학회 2008년 추계학술발표대회 논문집
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• pp.140-143
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• 2008

As the number of family living alone is expected to soar due to a change in socio-demographics like divorce, more middle-aged women returning to work, homes become smaller and so on. In addition to in 2020 these people will be increase so that 85 percent of the Koreans compose elderly living alone who is over 65. This study aims at developing a sharing-typed elderly people-centered rental model which is accessible in the community integration dimension as an alternative and finding out theirconscious, their need about residence. and we need to check about their major requirements on improvement step by step. so that we suggest the desirable way on the existing multi house. The model provides benefits in the social, economical and pragmatic dimensions as the families living alone get together and living with others, Particularly, as a residence model which reduces a psychological loneliness and at the same time enables the elderly to continue to live a life in the community while they live together with other people, this model could be a strategy which supports the "Aging in Place." This study is in progress via small group workshop which debate gradually about special subject with similar group member. So we can find the residence's preference on living environment in various condition and the member can imagine freely on their future living arrangement by giving the various informations which can be proceed in future. The workshop proceed three times. at the first workshop, we're check their living environment and satisfaction level. and second time we give the knowledge about shared-type rental house then discuss about the model. and last time we're listen to the residence's opinion.

• 한국식품영양학회지
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• 제33권2호
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• pp.174-182
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• 2020

Probiotics improve the immune system. However, the effects of its lactic acid bacteria on atopic dermatitis relief and inflammation improvement is not fully understood. Recently, one of the probiotics, Lactobacillus helveticus HY7801 (HY7801), was found to have an anti-inflammatory effect. In this study, we investigated the effects of HY7801 on atopic dermatitis-induced animal models. After four weeks of oral administration, the group treated with HY7801 showed amelioration of the atopic dermatitis compared to the group receiving placebo. In the HY7801 treated group, the epidermal hyper-proliferation and collagen deposition were inhibited compared to the placebo group, and the secretion amount of the inflammatory factors, such as TNF-α, IL-4 were reduced. In conclusion, these results suggest that HY7801 acts as a functional probiotic via amelioration of the atopic dermatitis such as a decrease of epidermal hyper-proliferation, and collagen deposition and anti-inflammatory effects.

• 한국조경학회지
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• 제30권3호
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• pp.25-34
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• 2002

The purpose of this paper is to discuss the function of microclimate amelioration of urban trees regarding the environmental benefits of street trees in summer, focusing on the heat pollution-urban heat island, tropical climate day's phenomenon and air pollution. We measured the diurnal variation of air/ground temperatures and humidity within the vegetation canopy with the meteorological tower observation system. Summertime air temperatures within the vegetation canopy layer were 1-2$^{\circ}C$ cooler than in places with no vegetation. Due to lack of evaporation, the ground surface temperatures of footpaths were, at a midafternoon maximum, 8$^{\circ}C$ hotter than those under trees. This means that heat flows from a place with no vegetation to a vegetation canopy layer during the daytime. The heat is consumed as a evaporation latent heat. These results suggest that the extension of vegetation canopy bring about a more pleasant urban climate. Diurnal variation of air/ground temperatures and humidity within the vegetation canopy were measured with the meteorological tower observation system. According to the findings, summertime air temperatures under a vegetation canopy layer were 1-2$^{\circ}C$ cooler than places with no vegetation. Due mainly to lack of evaporation the ground surface temperature of footpaths were up to 8$^{\circ}C$ hotter than under trees during mid-afternoon. This means that heat flows from a place where there is no vegetation to another place where there is a vegetation canopy layer during the daytime. Through the energy redistribution analysis, we ascertain that the major part of solar radiation reaching the vegetation cover is consumed as a evaporation latent heat. This result suggests that the expansion of vegetation cover creates a more pleasant urban climate through the cooling effect in summer. Vegetation plays an important role because of its special properties with energy balance. Depended on their evapotranspiration, vegetation cover and water surfaces diminish the peaks of temperature during the day. The skill to make the best use of the vegetation effect in urban areas is a very important planning device to optimize urban climate. Numerical simulation study to examine the vegetation effects on urban climate will be published in our next research paper.

• 한국조경학회지
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• 제18권3호통권39호
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• pp.23-37
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• 1990

The purpose of this study was to suggest, an ameliorated, 'standard of estimated unit manpower & material' in the Landscape Planting Work. To achieve this goal of this study, following process was performed to reach more advanced results. First, relevant domestic & foreign references were gathered & analyzed with a viewpoint of the system & contents within, Second, most similar foreign country‘s relevant 10 forms & actual site were surveyed, Third, actual site data were collected from the 17 selected landscape Planting sites Fourth, the collected data from reference study & actual site survey were analyzed and calculated. And Finally, analyzed data were reorganized & rearranged in good order with 3 principles to produce more ameliorated 'Standard of estimated unit manpower & material' in the landscape Planting Work. The suggested main results of this study include, 1. Reorganization of current system to transplanting(includes excavation & root ball wrapping), planting(includes tree & shrub), turfing & maintenance 2. Deletion of the Range of 'account of labor' & simultaneous distribution of 'account of labor' with a proposed regular ratio 3. Adjustment of the range of the plant's size 4. Amelioration of the level of 'Account of labor' 5. New establishment in maintenance items as Watering, Fertilizing & spraying chemicals on turf area. 6. Readjustment & new establishment of the backfill volume. 7. Actualization, readjustment & new establishment of the transportation amount.

• 안보군사학연구
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• 통권8호
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• pp.351-381
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• 2010

Established on February 1st, 2010, The ROKN maritime task flotilla has a goal to successfully cope with North Korea and other potential threats. Unlike precedents of its kind, The ROKN maritime task flotilla is expected to concentrate more an far-sea strategies than coastal strategies. In such circumstances however, the existing maritime logistics systems have limitations upon which to utterly support the operation conception of the ROKN maritime task flotilla seven. To ensure it's efficiency, transformation of the systems is prerequisite. The purpose of this study is to deduce an adequate maritime logistics system for the ROKN maritime task flotilla by evaluating the limitation of the current system and foreseeing its performance necessary abilities to operate in the future. In order to do this, the study presented problems and the direction of development on the structural and behavioral sides. Fist, regarding problems in the structure of maritime logistics system, the investigation pronounced the need of improvement in mobile logistics support ability and its speed. In addition, for the behavioral side, the need of improvement in logistics cooperation system and self-maintenance ability was affirmed. For the development of an adequate maritime logistics system, the study suggested the amelioration in the operation of an adequate mobile logistics support platform and the speed of the logistics using high-speed transportation such as planes for the structural side. Moreover, for the behavioral side, it recommended th enhancement of logistics cooperation system including the nations that already imported th weapon system, amelioration of self-maintenance ability, and necessity to operate mobile maintenance group.

• 한방비만학회지
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• 제18권2호
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• pp.83-95
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• 2018

Objectives: The aim of this study was optimized mixing ratio of mulberry leaf, mulberry fruit, and silkworm for amelioration of the metabolic syndrome by using response surface method (RSM). Methods: Antioxidant, antidiabetic and antihypertensive activities of fifteen mixed powder of mulberry leaf, mulberry fruit, and silkworm by RSM were measured as indicators of metabolic syndrome. Results: The optimal mixing ratio of mulberry leaves, mulberry fruits, and silkworm with the greatest antioxidant, antidiabetic and antihypertensive activities was as follows: 2.5890 of mulberry leaf (A), 0.1222 of mulberry fruit (B), 2.9999 of silkworm (C). At this time, it was predicted that the total polyphenol content was estimated to be 185.51 tannic acid equivalent mg/g, 1, 1-diphenyl-2-picrylhy drazyl radical scavenging activity 84.77%, 1-deoxynojirimycin content 415.66 mg/100 g, ${\alpha}-glucosidase$ inhibitory activity 64.31%, ${\gamma}-aminobutyric$ acid content 267.77 mg/100 g, potassium content 1,899.11 mg/100 g, and angiotensin-converting-enzyme inhibitory activity was estimated to be 73.78%. Conclusions: It was concluded that the significant effect of the mulberry leaf, mulberry fruit, and silkworm on the metabolic syndrome-related biological activity indices (antioxidant activity, antidiabetic activity and antihypertensive activity) was as follows: 2.5890 of mulberry leaf (A), 0.1222 of mulberry fruit (B), 2.9999 of silkworm (C).

• Journal of Animal Science and Technology
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• 제63권2호
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• pp.211-247
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• 2021

Livestock species experience several stresses, particularly weaning, transportation, overproduction, crowding, temperature, and diseases in their life. Heat stress (HS) is one of the most stressors, which is encountered in livestock production systems throughout the world, especially in the tropical regions and is likely to be intensified due to global rise in environmental temperature. The gut has emerged as one of the major target organs affected by HS. The alpha- and beta-diversity of gut microbiota composition are altered due to heat exposure to animals with greater colonization of pathogenic microbiota groups. HS also induces several changes in the gut including damages of microstructures of the mucosal epithelia, increased oxidative insults, reduced immunity, and increased permeability of the gut to toxins and pathogens. Vulnerability of the intestinal barrier integrity leads to invasion of pathogenic microbes and translocation of antigens to the blood circulations, which ultimately may cause systematic inflammations and immune responses. Moreover, digestion of nutrients in the guts may be impaired due to reduced enzymatic activity in the digesta, reduced surface areas for absorption and injury to the mucosal structure and altered expressions of the nutrient transport proteins and genes. The systematic hormonal changes due to HS along with alterations in immune and inflammatory responses often cause reduced feed intake and production performance in livestock and poultry. The altered microbiome likely orchestrates to the hosts for various relevant biological phenomena occurring in the body, but the exact mechanisms how functional communications occur between the microbiota and HS responses are yet to be elucidated. This review aims to discuss the effects of HS on microbiota composition, mucosal structure, oxidant-antioxidant balance mechanism, immunity, and barrier integrity in the gut, and production performance of farm animals along with the dietary ameliorations of HS. Also, this review attempts to explain the mechanisms how these biological responses are affected by HS.

• 동의신경정신과학회지
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• 제32권2호
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• pp.111-127
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• 2021

Objectives: To review and analyze clinical and preclinical evidence of effectiveness, safety, and underlying mechanisms of yokukansan (YKS), a herbal medicine, in alleviating aggression. Methods: Classical records on YKS were searched in the Korean Traditional Medicine Knowledge Database (KTMKD). By searching five electronic databases, prospective clinical studies and preclinical studies of YKS for alleviating aggression/agitation published up to March 30, 2021 were included. Results: Only two classical records on YKS were found from the KTMKD. A total of 11 clinical studies and 15 preclinical studies were found from the five electronic databases. Among 11 clinical studies, seven enrolled patients with dementia and four enrolled patients with other neuropsychiatric disorders. Most clinical studies reported significant improvement in one or more outcomes related to aggression in the YKS group after treatment. Among 15 preclinical studies, all studies except two reported a significant decrease in aggression/agitation-related behavior of YKS or yokukansankachimpihange. Suggested underlying mechanisms of YKS or yokukansankachimpihange for aggression/agitation in these studies included regulation of serotonin receptor, amelioration of abnormal glucocorticoid level related to the hypothalamic-pituitary-adrenal axis, regulation of orexin secretion, amelioration of degeneration in brain cells including glia cells, and suppression of excessive glutamatergic or dopaminergic activity. Conclusions: There were some clinical and preclinical evidence supporting the effectiveness and safety of YKS for alleviating aggression. Given that aggression is the most frequent and destructive symptoms of behavioral and psychological symptoms of dementia, applicability of YKS as a herbal medicine should be further investigated in future high-quality research.

• The Korean Journal of Pain
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• 제36권4호
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• pp.425-440
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• 2023

Background: Muscimol's quick onset and GABAergic properties make it a promising candidate for the treatment of pain. This systematic review and meta-analysis of preclinical studies aimed at summarizing the evidence regarding the efficacy of muscimol administration in the amelioration of nerve injury-related neuropathic pain. Methods: Two independent researchers performed the screening process in Medline, Embase, Scopus and Web of Science extracting data were extracted into a checklist designed according to the PRISMA guideline. A standardized mean difference (SMD [95% confidence interval]) was calculated for each. To assess the heterogeneity between studies, ² and chi-square tests were utilized. In the case of heterogeneity, meta-regression and subgroup analyses were performed to identify the potential source. Results: Twenty-two articles met the inclusion criteria. Pooled data analysis showed that the administration of muscimol during the peak effect causes a significant reduction in mechanical allodynia (SMD = 1.78 [1.45-2.11]; P < 0.0001; I² = 72.70%), mechanical hyperalgesia (SMD = 1.62 [1.28-1.96]; P < 0.0001; I² = 40.66%), and thermal hyperalgesia (SMD = 2.59 [1.79-3.39]; P < 0.0001; I² = 80.33%). This significant amendment of pain was observed at a declining rate from 15 minutes to at least 180 minutes post-treatment in mechanical allodynia and mechanical hyperalgesia, and up to 30 minutes in thermal hyperalgesia (P < 0 .0001). Conclusions: Muscimol is effective in the amelioration of mechanical allodynia, mechanical hyperalgesia, and thermal hyperalgesia, exerting its analgesic effects 15 minutes after administration for up to at least 3 hours.

• 한국동물위생학회지
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• 제46권1호
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• pp.1-13
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• 2023

Fatty liver hemorrhagic syndrome (FLHS) is a metabolic disorder found in caged layer hens and causes reduced egg production and sudden death. Dandelion (Taraxacum coreanum, TC) and milk thistle (Cirsium japonicum var. ussuriense, CJ) are well known wild herbs inhabiting Korean peninsula and presenting antioxidative effects. This study investigated alleviate effects of these herbal mixture (6:4, w/w) composed of dried powder of TC and CJ against fatty liver in laying hens. The herbs mixture 5.0, 10.0, 20.0 or 40.0 g/kg feed was provided via feed admixture for 3 weeks to laying hens having FLHS. FLHS was induced by intramuscular injection of β-estradiol (2 mg/kg bw) 2 times per week for 3 weeks and supply with high caloric feed. Egg production rate was reduced from 76.2% at pre-treatment to 49.4% at 1 week and further decreased according to β-estradiol treatment. Increment of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), total cholesterol (T-Chol) and total bilirubin (T-Bil) and decrement of serum superoxide dismutase (SOD) and glutathione peroxidase (GPX) with fatty liver were found by the treatment of β-estradiol. Supplementation of TC and CJ mixture via feed admixture recovered the reduction of egg production and attenuated serological changes and gross and pathological lesions of fatty liver with the best amelioration effects at 5 and 10 g TC and CJ mixture per kg feed. In conclusion, TC and CJ mixture attenuates FLHS by means of antioxidative effects. Further mechanistic study is required to explain TC and CJ's amelioration effects against FLHS in laying hens.