• Journal of Korean Neurosurgical Society
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• 제37권5호
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• pp.340-344
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• 2005

Objective: Posterior lumbar interbody fusion(PLIF), the current leading method of pedicle screw fixation combined with interbody fusion via posterior route, sometimes requires too much destruction of the facet joint than expected especially for the patient with a narrow spine. On the other hand, tranforaminal lumbar interbody fusion(TLIF) technique provides potential advantages over PLIF and can be chosen as a better surgical alternative to more traditional fusion methods in certain surgical conditions. Methods: From October 1999, 99 PLIF and 29 TLIF procedures were done for the patients with spinal stenosis and instability. Radiological data including the interpedicular distance and the size of the pedicles as well as the clinical parameters were collected retrospectively. The degree of resection of the inferior articular process was compared with the interpedicular distance in each patient who received PLIF. Results: No significant differences were found between PLIF and TLIF regarding the operation time, blood loss, duration of hospital stay, or short term postoperative clinical result. There were no complication with TLIF, but PLIF resulted in 9(9.1%) complications. During PLIF procedure, all patients(n=24) except one with the interpedicular distance shorter than 27mm required near complete or complete resection of the inferior articular processes, whereas only 6(31.5%) of 19 patients with the interpedicular distances longer than 30mm required the similar extent of resection. Conclusion: TLIF is better than PLIF in terms of the complication rate. The patient who had narrow interpedicular distance(<27mm) might be better candidate for TLIF.

• 한국방재학회 논문집
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• 제11권3호
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• pp.49-56
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• 2011

본 연구는 위험물 수송의 최적경로를 결정하는 방법론을 제안하였다. 위험물 차량의 최적경로를 결정할 때에는 위험도 최소화를 목적으로 하는 공공의 입장과 통행시간 최소화를 목적으로 하는 민간기업의 입장이 서로 상충한다. 본 연구에서는 이러한 다기준 의사결정(Multi-criteria decision making)문제 중 하나인 위험물 수송용 최적경로를 탐색하는 방법론으로 Efficient Vector Labeling(이하 EVL) 알고리즘을 제시하였다. EVL 알고리즘은 위험도와 통행시간을 동시에 고려하여 복수의 Pareto optimal 경로(또는 비지배경로)를 탐색하게 한다. 본 연구는 또한 탐색된 비지배경로간의 중복도를 제어할 수 있도록 설계하였다. 개발된 Efficient Vector Labeling 알고리즘을 Test bed network에 적용하여 기존의 경로탐색 방법론과 비교하였다. 적용 결과 새로운 알고리즘이 기존의 알고리즘보다 합리적인 대안경로를 탐색할 수 있는 것으로 분석되었다.

• Neurospine
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• 제15권4호
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• pp.388-393
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• 2018

Objective: Computed tomography following myelography (CTM) revealed an unusual flow of contrast dye into the anterior median fissure (AMF) in a patient with cervical spondylotic myelopathy. Since then, several AMF configurations have been observed on CTM. Therefore, we evaluated morphological patterns of the AMF on CTM and investigated the significance and mechanisms of contrast dye flow into the AMF. Methods: Morphological patterns of the AMF on CTM were examined in 79 patients. Group A (24 patients) underwent surgery because of symptomatic cervical myelopathy. Group B (43 patients) had no clinical symptoms but showed spinal cord compression on CTM. Group C (12 patients), who showed neither clinical symptoms nor cord changes, underwent CTM for lumbar lesion evaluation. AMF patterns were classified into 4 types according to their configurations on CTM (reversed T, Y, V, and O types). Results: In group B, the reversed T type and Y type appeared significantly more often near the compressed portion (p<0.001). A similar tendency was seen in group A. The V and O types were most frequently observed in group C (p<0.001). Conclusion: On CTM, contrast dye tends to flow into the AMF of the cervical cord when the spinal cord is compressed. We speculate that there may be 3 possible mechanisms for this phenomenon: deformation of the epipial layer of the AMF due to cervical cord compression, AMF dilatation due to atrophy of the anterior funiculus or anterior horn, and temporary AMF dilatation when it becomes an alternative route for cerebrospinal fluid circulation.

• 정보보호학회논문지
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• 제14권5호
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• pp.49-56
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• 2004

IETF mobileip WG에서 MN(Mobile Node)의 위치를 나타내는 '바인딩정보'를 안전하게 CN(Correspondent Node)에게 송신하여 최적경로를 설정하는 RR(Return Routability)프로토콜을 드래프트 문서로 제안하고 있다. 하지만 이 프로토콜의 시작 주체 및 시점이 MN에 의해 이루어짐에 따라 최적경로설정 지연에 따른 홈 네트워크의 부담 및 통신지연을 증가시키고 불필요한 메시지 교환에 따른 통신부담을 문제점으로 지적할 수 있다. 본 논문에서는 상기와 같은 문제점의 해결방안으로 RR프로토콜의 시작 주체 및 시점을 MN에서 HA(Home Agent)로 변경하여 HA가 CN으로부터 첫 번째 패킷을 수신했을 때 최적경로설정을 시작하도록 개선된 RR프로토콜을 제안하였다. 이를 통해서 최적경로설정에 소용되는 시간을 단축하고 교환되는 메시지 수를 감소시켜 통신부담을 경감시키는 효과를 얻을 수 있다. 이럼에도 불구하고 기존의 RR프로토콜과 동일한 보안수준을 제공한다.

• Membrane and Water Treatment
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• 제12권1호
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• pp.43-49
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• 2021

The Commercial polymeric membranes like Polysulfone (PSF), Polyvinylidene difluoride (PVDF) and Polyacrylonitrile (PAN) which are an integral part of water purification investigation were chosen for the shockwave (SW) exposure experiment. These membranes were prepared by blending polymer (wt. %) / DMF (solvent) followed by phase-inversion casting technique. Shockwaves are generated by using Reddy Tube lab module (Table-top Shocktube) with range of pressure (1.5, 2.5 and 5 bar). Understanding the changes in membrane before and after shock wave treatment by parameters, i.e., pure water flux (PWF), rejection (%), porosity, surface roughness (AFM), morphology (SEM) and contact angle which can significantly affect the membrane's performance. Flux values PSf membranes shows increase, 465 (pristine) to 524 (1.5wt%) LMH at 50 Psi pressure and similar enhancement was observed at 100Psi (625 to 696 LMH). Porosity also shows improvement from 73.6% to 76.84% for 15wt% PSf membranes. It was observed that membranes made of polymers such as PAN and PSF (of high w/w %) exhibits some resistance against shockwaves impact and are stable compared to other membranes. Shockwave pressure of up to 1.5 bar was sufficient enough to change properties which are crucial for performance. Membranes exposed to a maximum pressure of 5 bar completely scratched the surface and with minimum pressure of 1.5bar is optimum enough to improve the water flux and other parameters. Initial results proved that SW may be suitable alternative route to minimize/control membrane fouling and improve efficiency.

• 한국초전도저온공학회:학술대회논문집
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• 한국초전도저온공학회 2002년도 학술대회 논문집
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• pp.340-340
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• 2002

In an effort to develop alternative single buffer layer technology for YBa$_2$Cu$_3$O$_{7-{\delta}}$ (YBCO) coated conductors, we have investigated both LaMnO$_3$, (LMO) and La$_2$Zr$_2$O$_{7}$ (LZO) as potential buffer layers. High-quality LMO films were grown directly on textured Ni and Ni-W (3%) substrates using rf magnetron sputtering. Highly textured LZO buffers were grown on textured Ni substrates using sol-gel alkoxide processing route. YBCO films were then grown on both LMO and LZO buffers using pulsed laser deposition. Detailed X-ray studies have shown that YBCO films were grown on both LMO and LZO layers with a single epitaxial orientation. A high J$_{c}$ of over 1 MA/cm$^2$ at 77 K and self-field was obtained on YBCO films grown on both LMO-buffered Ni or Ni-W substrates, and also on LZO-buffered Ni substrates. We have identified LaMnO$_3$ as a good diffusion barrier layer for Ni and it also provides a good template for growing high current density YBCO films. Similarly we have also demonstrated the growth of high J$_{c}$ YBCO films on all solution buffers. We will discuss in detail about our buffer deposition processes. processes.s.s.s.s.

• 보건행정학회지
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• 제3권1호
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• pp.1-24
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• 1993

This study is designed to find clues to make a plan for efficient hospital bed utilization. Author has tried to estimate the level of appropriateness and to find out factors affecting intra-hospital variation of inappropriate bed utilization using modified Appropriateness Evaluation Protocol of which criteria are based on service intensity and patients' conditions. Systematic random sampling was done from the population of inpatients during one month in on university hospital. Data were collected by concurrent and retrospective medical record review and analysed by multiple logistic regression. In medical services, 83.5% of admission reveals appropriate and the level of inappropriate admission shows significant differences by patients' residence, type of department admitted to, admission 개\ulcorner, and length of stay. In surgical services, 97.3% and 34.7% are appropriate in location and timing of surgery respectively. Inappropriate timing of surgery differs significantly depending on patients' age, type of department admitted to, admission route, and length of stay. Sixty two percent of hospital days shows appropriate and the level of inappropriateness show marked differences by patients'age, type of services, admission routes, part of the month, part of the stay, and length of stay. Inappropriate hospital days are due to inappropriate level of care, premature admission, improper scheduling of diagnostic or therapeutic procedures, and problems in scheduling surgery in sequence. In conclusion, substantially high proportion of inappropriate hospital bed utilization was confirmed. To reduce it, it is necessary to develop alternative services with which can replace inpatient services, and to introduce utilization management system which may include internal peer review.

• Journal of Microbiology and Biotechnology
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• 제33권4호
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• pp.441-448
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• 2023

Brucellosis is a contagious zoonotic disease that infects millions of people annually with hundreds of millions more being exposed. It is caused by Brucella, a highly infectious bacterial species capable of infecting humans with an estimated dose of 10-100 organisms. Sirtuin 1 (SIRT1) has been reported to contribute to prevention of viral diseases as well as a chronic infection caused by Mycobacterium bovis. Here, we investigated the role of SIRT1 in the establishment of Brucella abortus infection in both in vitro and in vivo systems using the reported SIRT1 activators resveratrol (RES), piceatannol (PIC), and ginsenoside Rg3 (Rg3). In RAW264.7 cells, SIRT1 activators did not alter the adherence of Brucella or Salmonella Typhimurium. However, reduced uptake of Brucella was observed in cells treated with PIC and Rg3, and survival of Brucella within the cells was only observed to decrease in cells that were treated with Rg3, while PIC treatment reduced the intracellular survival of Salmonella. SIRT1 treatment in mice via oral route resulted in augmented Brucella resistance for PIC and Rg3, but not RES. PIC treatment favors Th2 immune response despite reduced serum pro-inflammatory cytokine production, while Rg3-treated mice displayed high IL-12 and IFN-γ serum production. Overall, our findings encourage further investigation into the complete mechanisms of action of the different SIRT1 activators used as well as their potential benefit as an effective alternative approach against intracellular and extracellular pathogens.

• 대한토목학회논문집
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• 제30권3D호
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• pp.199-204
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• 2010

본 연구는 고속도로에 설치되어 있는 안내표지를 효과적으로 개선하는데 그 목적이 있다. 국내 고속도로에 설치되어 있는 안내표지는 지점중심 안내체계, 과도한 정보량, 출구번호 이용률 저조, 차로지정 안내의 미비에 따라 효율이 크게 떨어지고 있다. 이러한 문제점을 보완한 3개의 개선안을 제시하였고, 선호도 조사와 판독시간 검증을 통해 최적안을 선정하였다. 최적안은 기존표지에 비해 판독시간이 통계적으로 유의하게 단축된 것으로 분석되었다. 기존의 표지는 원거리에서는 출구에 대한 많은 정보를 전달하는데 비해, 근거리에서 오히려 적은 정보를 전달하고 있는데 비해, 개선 표지는 원거리에서는 개략적인 정보를, 근거리에서는 보다 상세한 정보를 제공한다. 0m 지점에서는 운전자가 목적지에 따른 노선을 효과적으로 선택할 수 있도록 차로지정 표지를 문형식으로 설치하여 안내하도록 하였다.

• 한국전자통신학회논문지
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• 제18권6호
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• pp.1073-1080
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• 2023

인터넷 네트워크의 발전과 속도 개선, 이를 배경으로 한 각종 플랫폼의 발전은 다양한 콘텐츠의 생산과 소비의 급속한 확장을 불러왔다. 하지만 기존의 IP를 기반으로 한 인터넷 체계는 이런 급속한 데이터의 증가에 효율적으로 대처할 수 없는 현황이다. 이에, 콘텐츠 중심 네트워크(CCN, Contents Centric Network)라는 대안이 등장해 호스트 중심이 아닌 콘텐츠를 중심으로 보다 효율적인 데이터 송수신이 가능해졌다. 본 논문에서는 CCN의 주요 연구 분야 중 하나인 실시간 스트리밍 서비스에서의 중간노드 이동성에 대해 다룰 것이며, RSSI 감지를 통한 보다 효율적인 경로 전환을 통해 네트워크 과부하를 최소화할 것이다. 즉, 정보요청자와 정보제공자 사이에 위치한 중간노드가 이동했을 때 예비 경로를 선택하고 전환하는 방법을 개선함으로써 데이터 전송의 단절은 없으면서도 네트워크에 경로 전환으로 인한 불필요한 부하가 발생하지 않도록 관리하는 매커니즘을 제안한다.