• Journal of Korean Neurosurgical Society
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• 제47권1호
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• pp.17-25
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• 2010

Objective: The focus of this study is brain plasticity associated with semantic aspects of language function in patients with medial temporal lobe epilepsy (mTLE) Methods: Using longitudinal functional magnetic resonance imaging (fMRI), patterns of brain activation were observed in twelve left and seven right unilateral mTLE patients during a word-generation task relative to a pseudo-word reading task before and after anterior temporal section surgery. Results: No differences were observed in precentral activations in patients relative to normal controls (n = 12), and surgery did not alter the phonological-associated activations. The two mTLE patient groups showed left inferior prefrontal activations associated with semantic processing (word-generation>pseudo-word reading), as did control subjects. The amount of semantic-associated activation in the left inferior prefrontal region was negatively correlated with epilepsy duration in both patient groups. Following temporal resection, semantic-specific activations in inferior prefrontal region became more bilateral in left mTLE patients, but more left-lateralized in right mTLE patients. The longer the duration of epilepsy in the patients, the larger the increase in the left inferior prefrontal semantic-associated activation after surgery in both patient groups. Semantic activation of the intact hippocampus, which had been negatively correlated with seizure frequency, normalized after the epileptic side was removed. Conclusion: These results indicate alternation of semantic language network related to recruitment of left inferior prefrontal cortex and functional recovery of the hippocampus contralateral to the epileptogenic side, suggesting an intra- and inter-hemispheric reorganization following surgery.

• 농업과학연구
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• 제4권1호
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• pp.88-93
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• 1977

흙의 압밀시험(壓密試驗)에서 하중증가율(荷重增加率)을 변화(變化)시켰을 때 압밀(壓密)의 제계수에 미치는 영향을 고찰하기 위하여 표준압밀시험(標準壓密試驗)에서 적용하는 전하량(戰荷重) 증가율(增加率)을 여러가지로 변경(變更)하여 압밀시험(壓密試驗)을 실시(實施)하여 다음과 같은 결과(結果)를 얻었다. 하중증가율(荷重增加率)이 클수록 침하량(沈荷量)은 크나 팽창량(膨脹量)은 하중증가율(荷重增加率)과 무관(無關)하다. 일침압밀(一沈壓密) 완자점(完子點)까지의 시간은 하중증가율(荷重增加率)이 작을수록 큰 값을 나타냈고, 또 과압밀 영역에서는 하중증가(荷重增加)에 따라 일침압밀완자점(一沈壓密完子點)의 시간(時間)은 큰 값을 나타내고 정규압밀(正規壓密)영역에서는 거의 일정(一定)한 값을 나타냈다. 압밀계수(壓密係數)는 재하량(載荷重)이 증가(增加)함에 따라 감소(減少)하며 하중증가율(荷重增加率)이 클수록 압밀계수(壓密係數)의 값도 크게 나타났다. 이침압밀비(二次壓密比)의 값은 곡연(曲緣)의 변곡점(變曲點)과 거의 일치(一致)되는 점(點)에서 최대(最大)로 되었다.

• 한국수산과학회지
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• 제16권2호
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• pp.75-81
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• 1983

1981년 7월부터 1982년 6월까지 매월 부산 해운대 동백섬 해안에서 낚시와 삼중자망으로 채집한 노래미(Agrammus agrammus)의 추체를 사용하여 연령과 성장을 조사하였다. 추체반경과 어체의 전장 간에는 직선회귀관계가 있었다. 추체의 불투명대에서 투명대로 이행하는 경계를 윤문으로 간주한 본연구에서의 윤문은 매년 $7{\sim}8$월에 형성되었고, 제1, 2, 3, 4 윤문이 형성되는 데는 각각 0.67년, 1.67년, 2.67년, 3.67년이 걸렸다. 비만도의 월별변화로 조사한 산란기는 12월로 추정되었다. 각 윤문이 형성될 때의 전장을 역계산하여 다음과 같은 버트란피 성장식을 구할 수 있다. $l_t=31.68(1-e^{-0.189(t+1.458)})\;W_t=528.30(1-e^{-0.189(t+1.458)})^3$이 식으로부터 구한 추정전장은 실측전장과 잘 일치하였다.

• 전자공학회논문지CI
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• 제39권6호
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• pp.11-23
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• 2002

한국어 형태론에 대한 기존의 전산모형은 선형적인 것들로 단어 내부구조 분석보다 형태소 분리 문제에만 관심을 두고 있다. 이러한 선형적 전산모형을 구문 분석 과정과 통합적으로 고려할 경우, 구문 단위 요소의 형성을 위해 형태소 분석 결과를 묶어야만 하는 추가적인 과정이 필요할 뿐만 아니라 의미적 직관성을 얻기도 어려웠다. 본 논문에서는 형태소 분리와 구문 요소 형성뿐만 아니라 단어의 구조 분석까지도 통합적으로 다룰 수 있는 단어통사론적 시각에 따른 전산 모형을 제안한다. 먼저 형태소 분리와 변형 문제를 다루기 위해 2단계형태론의 형식화를 도입하고, 품사 문맥을 반영하기 위해 기능성 구분문자를 제안한다. 그리고 형태소의 통사적 결합 검사를 위해 GLR에 기반한 변형 알고리즘을 제안한다.

• International Journal of Oral Biology
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• 제32권4호
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• pp.127-133
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• 2007

Oral squamous cell carcinoma (OSCC) is the most common malignancy and is a major cause of worldwide cancer mortality. The proto-oncogene c-myb plays an important role in regulation of cell growth and differentiation, and it is expressed at high levels in hematopoietic cells and many other types of cancers. However, the function of c-myb is not well known in OSCC. The present study aimed to reveal the function of c-myb and to test the alternation of cell growth and signaling by c-myb in OSCC. In this study, c-myb and dominant-negatibe myb(DNmyb) were expressed in an adenovirus-mediated gene delivery system to KB cells. The over-expressed c-myb brought increased cellular proliferation compared with control cells. However, DN-myb infected KB cells showed significant reduction of cell growth and enhanced induction of apoptosis to activate PARP and caspase 9. c-myb induced increase of IGF-I, -II and IGF-IR expressions while DN-myb down-regulated these expression. Activation of ERK and Akt/PKB pathway was shown only in c-myb transduced cells. These findings suggest that the role of c-myb in cell growth of oral cancer cells is partially mediated through the modulation of IGFs, ERK and Akt/PKB. From this results, DN-myb is strongly recommended as a curable gene for the treatment of c-myb dependent malignancies such as OSCC.

• 한국태양에너지학회 논문집
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• 제27권1호
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• pp.47-54
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• 2007

Interests on renewable energy are increased due to oil price and environmental problems aroused from the fossil energy usage. In this study, performances of a solar assisted hybrid heat pump system are analyzed by experimental method. The developed system could runs at two types of operating mode. When the storage temperature is higher than the set temperature, the stored hot water in storage tank is supplied to the load directly. On the other hand, when the storage temperature lower than the set temperature, the water inside of the storage tank is used as heat source of the heat pump. In this study, the system control temperature for the alternation of the operating mode is set to $40^{\circ}C$ of the storage tank outlet. As results, it is founded that the COP of the developed heat pump system shows between 3.0 and 3.5. It is resonable performance for the heating system with a renewable energy as secondary heat source. The solar collect used in this study could supplies heat to the storage tank at over 400 W/m2 solar intensity. If the irradiation is lower than the 400 W/m2, the circulation pump stored and it could not supply heat to the storage tank. It is found that the difference temperature between the outlet of the storage tank and collector is $3^{\circ}C$. Even though, the extended study should be conducted to get a optimum performance of the developed system with various operating condition and control strategies.

• Journal of Acupuncture Research
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• 제27권5호
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• pp.51-58
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• 2010

Objectives : The purpose of this study is to assess the effect of laser acupuncture at $HT_7$ for reducing mental stress using power spectrum analysis of the heart rate variability. Methods : 36 healthy volunteers(control group: 18, treatment group: 18) participated in this study. After instrumentation and 5-minute rest period, 5-minute metal stress by operation was provided. HRV was recorded before and after the mental stress(1st, 2nd HRV). After 2nd HRV recording, the control group rested for 15 minutes without any treatments. Participants in the treatment group received laser acupuncture to $HT_7$ unilaterally and rested for 15minutes. Points were irradiated for 60seconds, and the intensity was 1.8J(output 20%). And then 3rd HRV was recorded. Results : In simple rest group, LF norm showed a significant change after mental stress. In laser acupuncture group, LF norm, HF norm, LF, HF and LF/HF ratio showed a significant change after mental stress. But there were no significant difference between two groups(ANCOVA test, p>0.05). In laser acupuncture group, LF norm, HF norm, HF and LF/HF ratio showed a significant change after laser acupuncture treatment. And there were significant differences between two groups(p<0.05). Conclusions : This study suggests that laser acupuncture at $HT_7$ can regulate and prevent the alternation of autonomic nervous system due to mental stress.

• Imaging Science in Dentistry
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• 제40권3호
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• pp.115-121
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• 2010

Purpose : The purpose of this study was to accurately analyze the radiographic characteristics of dentigerous cyst (DC) with multiplanar images of cone beam computed tomography (CBCT). Materials and Methods : Thirty eight radiographically and histopathologically proven cases of DCs were analyzed with panoramic radiograph and CBCT, retrospectively. The radiographic CT pattern, symmetry of radiolucency around the unerupted tooth crown, ratio of long length to short length, degree of cortical bone alternation, effects on adjacent tooth, and cyst size were analyzed. Relative frequencies of these radiographic features were evaluated. In order to compare the CBCT features of DC with those of odontogenic keratocyst (OKC), 9 cases of OKCs were analyzed with the same method radiographically. Results : DCs consisted of thirty unilocular cases (79.0%), seven lobulated cases (18.4%) and one multilocular case (2.6%). Eight were asymmetric (21.0%) and thirty were symmetric (79.0%). Maxillary DC showed rounder shape than mandibular DC (L/S ratio; maxilla 1.32, mandible 1.67). Alternations of lingual cortical bone (14 cases, 48.2%) were more frequent than those of buccal side (7 cases, 24.1%). CBCT images of DC showed definite root resorption and bucco-lingual tooth displacement. These findings were hardly observed on panoramic radiographs of DCs. Comparison of CBCT features of DC with those of OKC showed several different features. Conclusions : CBCT images of DC showed various characteristic radiographic features. Therefore, CBCT can be helpful for the diagnosis of DC radiographically.

• 디지털콘텐츠학회 논문지
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• 제4권2호
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• pp.147-155
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• 2003

우리나라 부동산의 예측할 수 없는 매매가로 인해 경제가 혼란스러운 최근에 토지정책의 패러다임 전환론과 더불어 토지평가자료의 객관적 적정성에 대한 문제가 심각하게 논의되고 있다. 특히 공시지가자료가 공신력을 인정받지 못함으로서, 토지보상금이나 개발부담금을 산출하는데 필요한 지가가 별도의 방법으로 산정 되는 등 공적지가 산정의 일원화를 목적으로 도입된 공시지가제도가 기본기능을 수행하지 못한다는 비판이 제기되고 있다. 공시지가의 적정성을 위해 가장 중요한 사항은 토지평가 항목이 합리적으로 선정되어야 한다. 또한 인터넷을 통한 정보의 홍수시대에 살고 있는 현대인들에게 신뢰할 수 있는 토지평가자료를 제공해주는 디지털컨텐츠의 개발이 시급한 상황에 있다. 본 연구에서는 통계적 기법을 이용하여 실거래지가와 형평성을 유지하도록 하는 토지평가모형 개발의 방법론을 제안하고 실거래지가에 기초한 토지평가 디지털컨텐츠를 개발하기 위하여 용도지역별로 실거래지가에 영향을 미치는 항목을 기존의 부동산 웹사이트의 자료를 이용하여 분석한다.

• Applied Microscopy
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• 제34권2호
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• pp.131-137
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• 2004

돌돔의 피부는 크게 상피층과 진피층으로 구분되며, 상피층은 지지세포, 선세포 및 부속세포로 구성된다. 지지세포는 표면세포, 중간세포 및 기저세포, 선세포는 점액세포와 곤봉상세포, 그리고 부속세포는 염세포가 관찰된다. 표면세포는 편평형 또는 입방형으로서 타원형의 핵을 가지고, 미세융기(microridge)들이 발달되어 있으며 glycocalyx가 관찰된다. 중간세포는 타원형에 가깝고 원형에 가까운 핵을 가진다. 기저세포는 원주형으로서 핵은 세포질의 상부에 위치한다. 점액세포는 타원형으로 세포질은 타원형의 분비과립이 대부분을 차지하며, AB-PAS (pH 2.5)에 청색으로 반응하였다. 곤봉상세포는 세포질에 많은 액포와 미세섬유다발을 관찰할 수 있다. 부속세포인 염세포 세포질의 대부분이 미토콘드리아로 가득 채워져 있다. 색소세포는 세포질에 전자밀도가 높은 색소과립들을 함유한 종류와 반사소판을 함유한 종류로 구분된다.