• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.16 no.1
• /
• pp.173-187
• /
• 2022

Recent studies have focused on self-management of hypertension using smart devices (cellular phones, tablets, watches). It has proven to be an effective tool for early detection and control of high Blood Pressure (BP) without affecting patients' daily routines. This systematic review surveys the existing self-monitoring systems, evaluate their effectiveness and compares the different approaches. We investigated the current systems in terms of various attributes, including methods used, sample size, type of investigation, inputs/ outputs, rate of success in controlling BP, group of users with higher response rate and beneficiaries, acceptability, and adherence to the system. We identified some limitations, shortcomings, and gaps in the research conducted recently studying the impact of mobile technology on managing hypertension. These shortcomings can generate future research opportunities and enable it to become more realistic and adaptive. We recommended including more observable factors and human behaviors that affect BP. Furthermore, we suggested that vital monitoring/logging and medication tuning are insufficient to improve hypertension control. There is also a need to observe and alter patient behavior and lifestyles.

• Journal of information and communication convergence engineering
• /
• v.20 no.4
• /
• pp.265-272
• /
• 2022

The most effective method to improve information system capabilities is to enable instant access to several relational database sources and transform data with a logical structure into multiple target relational databases. There are numerous data transformation tools available; however, they typically contain fixed procedures that cannot be changed by the user, making it impossible to fulfill the near-real-time data transformation requirements. Furthermore, some tools cannot build object references or alter attribute constraints. There are various situations in which tool changes in data type cause conflicts and difficulties with data quality while transforming between the two systems. The R-programming language was extensively used throughout this study, and several different relational database structures were utilized to complete the proposed study. Experiments showed that the developed study can improve the performance of information systems by interacting with and exchanging data with various relational databases. The study addresses data quality issues, particularly the completeness and integrity dimensions of the data transformation processes.

• International Journal of Internet, Broadcasting and Communication
• /
• v.14 no.3
• /
• pp.161-170
• /
• 2022

Recently, NAND-type flash memory has been regarded to be new promising storage media for large-scale database systems. For flash memory to be employed for that purpose, we need to reduce its expensive update cost caused by the inablity of in-place updates. To remedy such a drawback in flash memory, we propose a new flash-aware buffering scheme that enables virtual flushing of dirty pages. To this end, we slightly alter the tradional algorithms used for the logging scheme and buffer management scheme. By using the mechanism of virtual flushing, our proposed buffering scheme can efficiently prevent the frequenct occureces of page updates in flash storage. Besides the advantage of reduced page updates, the proposed viurtual flushing mechanism works favorably for shorneing a recocery time in the presense of failure. This is because it can reduce the time for redo actions during a recovry process. Owing to those two benefits, we can say that our scheme couble be very profitable when it is incorporated into cutting-edge flash-based database systems.

• IMMUNE NETWORK
• /
• v.16 no.5
• /
• pp.261-270
• /
• 2016

The human immune system has evolved to fight against foreign pathogens. It plays a central role in the body's defense mechanism. However, the immune memory geared to fight off a previously recognized pathogen, tends to remember an original form of the pathogen when a variant form subsequently invades. This has been termed 'original antigenic sin'. This adverse immunological effect can alter vaccine effectiveness and sometimes cause enhanced pathogenicity or additional inflammatory responses, according to the type of pathogen and the circumstances of infection. Here we aim to give a simplified conceptual understanding of virus infection and original antigenic sin by comparing and contrasting the two examples of recurring infections such as influenza and dengue viruses in humans.

• Nonlinear Functional Analysis and Applications
• /
• v.29 no.2
• /
• pp.597-620
• /
• 2024

In this study, the conformable fractional derivative(CFD) of order 𝝔 in conjunction with the LC operator of orderρ is used to develop the model of the transmission of the A(H1N1) influenza infection. A brand-new A(H1N1) influenza infection model is presented, with a population split into four different compartments. Fixed point theorems were used to prove the existence of the solutions and uniqueness of this model. The basic reproduction number R₀ was determined. The least and most sensitive variables that could alter R₀ were then determined using normalized forward sensitivity indices. Through numerical simulations carried out with the aid of the Adams-Moulton approach, the study also investigated the effects of numerous biological characteristics on the system. The findings demonstrated that if 𝝔 < 1 and ρ < 1 under the CFD, also the findings demonstrated that if 𝝔 = 1 and ρ = 1 under the CFD, the A(H1N1) influenza infection will not vanish.

• Earthquakes and Structures
• /
• v.11 no.6
• /
• pp.1077-1099
• /
• 2016

One of the main shortcomings in the current passive base isolation system is lack of adaptability. The recent research and development of a novel adaptive seismic isolator based on magnetorheological elastomer (MRE) material has created an opportunity to add adaptability to base isolation systems for civil structures. The new MRE based base isolator is able to significantly alter its shear modulus or lateral stiffness with the applied magnetic field or electric current, which makes it a competitive candidate to develop an adaptive base isolation system. This paper aims at exploring suitable control algorithms for such adaptive base isolation system by developing a close-loop semi-active control system for a building structure equipped with MRE base isolators. The MRE base isolator is simulated by a numerical model derived from experimental characterization based on the Bouc-Wen Model, which is able to describe the force-displacement response of the device accurately. The parameters of Bouc-Wen Model such as the stiffness and the damping coefficients are described as functions of the applied current. The state-space model is built by analyzing the dynamic property of the structure embedded with MRE base isolators. A Lyapunov-based controller is designed to adaptively vary the current applied to MRE base isolator to suppress the quake-induced vibrations. The proposed control method is applied to a widely used benchmark base-isolated structure by numerical simulation. The performance of the adaptive base isolation system was evaluated through comparison with optimal passive base isolation system and a passive base isolation system with optimized base shear. It is concluded that the adaptive base isolation system with proposed Lyapunov-based semi-active control surpasses the performance of other two passive systems in protecting the civil structures under seismic events.

• Biomolecules & Therapeutics
• /
• v.21 no.2
• /
• pp.173-179
• /
• 2013

Objective of present study was to prepare and characterize self-nanoemulsifying drug delivery system (SNEDDS) of lutein and to evaluate its effect on bioavailability of warfarin. The SNEDDS was prepared using an oil, a surfactant, and co-surfactants with optimal composition based on pseudo-ternary phase diagram. Effect of the SNEDDS on the bioavailability of warfarin was performed using Sprague Dawley rats. Lutein was successfully formulated as SNEDDS for immediate self-emulsification and dissolution by using combination of Peceol as oil, Labrasol as surfactant, and Transcutol-HP or Lutrol-E400 as co-surfactant. Almost complete dissolution was achieved after 15 min while lutein was not detectable from the lutein powder or intra-capsule content of a commercial formulation. SNEDDS formulation of lutein affected bioavailability of warfarin, showing about 10% increase in $C_{max}$ and AUC of the drug in rats while lutein as non-SNEDDS did not alter these parameters. Although exact mechanism is not yet elucidated, it appears that surfactant and co-surfactant used for SNEDDS formulation caused disturbance in the anatomy of small intestinal microvilli, leading to permeability change of the mucosal membrane. Based on this finding, it is suggested that drugs with narrow therapeutic range such as warfarin be administered with caution to avoid undesirable drug interaction due to large amount of surfactants contained in SNEDDS.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.44 no.4
• /
• pp.273-281
• /
• 2008

In this study, the effect of slope length and angle at the entrance to fishing pots on the size of captured shrimp was examined to determine the optimal design of pots for use in Hokkaido, Japan. The purpose of the current study was to optimize the design of shrimp pots to allow greater control over the size of captured individuals for the purposes of shrimp resource management. Tank experiments were conducted to determine the optimal slope length and slope angle by analyzing the sizes of shrimp entering 10 model pots with combinations of five different slope lengths on slope angle of current shrimp pot, and five different angles on slope length of current shrimp pot. The results showed that, as the slope length of the pot increased, the size of individuals which entered the pot increased. In addition, as the slope angle was elevated in each of the five different slope angle treatments, the size of individuals entering was also increased.

• Journal of Institute of Control, Robotics and Systems
• /
• v.7 no.11
• /
• pp.891-895
• /
• 2001

An alternative inverse feedback structure for adaptive active control of periodic noise is introduced for systems with nonminimum phase cancellation path. To obtain the inverse model of the nonminimum phase cancellation path, the cancellation path model can be factorized into a minimum phase term and a maximum phase term. The maximum phase term containing unstable zeros makes the inverse model unstable. To avoid the instability, we alter the inverse model of the maximum phase system into an anti-causal FIR one. An LMS predictor estimates the future samples of the noise, which are necessary for causality of both anti-causal FIR approximation for the stable inverse of the maximum phase system and time-delay existing in the cancellation path. The proposed method has a faster convergence behavior and a better transient response than the conventional filtered-x LMS algorithms with the same internal model control structure since a filtered reference signal is not required. We compare the proposed methods with the conventional methods through simulation studies.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.12
• /
• pp.7277-7282
• /
• 2014

In this study, the gradient descent algorithm was used for FLC analysis and the algorithm was used to represent the effects of nonlinear parameters, which alter the antecedent and consequence fuzzy variables of FLC. The controller parameters choose the control variable by iteration for gradient descent algorithm. The FLC consists of 7 membership functions, 49 rules and a two inputs - one output system. The system adopted the Min-Max inference method and triangle type membership function with a 13 quantization level.