• Journal of Chest Surgery
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• 제16권3호
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• pp.289-294
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• 1983

The report is concerned to our experience of 12 cases of open heart surgery under the extracorporeal circulation at the Department of Thoracic and Cardiovascular Surgery, Chosun University Hospital during the period between Nov, 1979 and April, 1983. 1. There were 4 cases of congenital anomaly and 8 cases of acquired heart disease. 2. There were 6 male and 6 female patients with a mean age of 20 years. [range 9 to 33 years]. 3. The cases induced 2 ventricular septal defect, 2 atrial septal defects and 8 acquired valvular heart diseases. 4. The surgical managements were 2 primary repair for atrial septal defect and 2 patch closure for ventricular septal defect, 1 triple valve replacement [AVR MVR TVR], 1 aortic valve replacement, 4 double valve replacement [AVR MVR] and 2 open mitral commissurotomy for pure mitral stenosis. 5. The average cardiopulmonary bypass time was 61.5 minutes for congenital heart disease and 201.4 minutes for acquired valvular heart disease and the average aortic cross clamping time was 36.75 minutes for the former and 165.6 minutes for the latter. 6. Postoperatively, there were 1 Alopecia, 1 Electric burn and 1 wound infection as complication. 7. Overall operative mortality was 8.3%. 7. All patients received valve replacement were recommended anticoagulation with persantin.

• 대한수의학회지
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• 제51권2호
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• pp.171-175
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• 2011

Malignant Sertoli cell tumor was diagnosed in a 5-year-old male Shih Tzu dog. Clinical features of the dog were anorexia, urinary incontinence, constipation, anemia, alopecia, and epistaxis. The dog also had unilateral cryptorchid testis in the abdomen. Several abdominal and thoracic masses were identified on radiography. Grossly, the cryptorchid testicular mass was markedly enlarged to 8 cm in diameter. On cut surface, firm and well demarcated milk-white neoplastic areas were irregularly separated by white fibrous bands. Histologically, the testicular mass was diagnosed as tubular pattern Sertoli cell tumor. In addition, abdominal and mediastinal lymph nodes metastasis were found. Immunohistochemically, the tumor cells were strongly positive for vimentin and neuron specific enolase, but negative for S-100 and cytokeratin.

• 대한한방내과학회지
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• 제3권1호
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• pp.41-48
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• 1986

1. The cause of Pehuh is deficiency of Peki(肺氣). Symptoms are tachypnea, thirst and deafness of hemoptysis. In treatment, control it's Ki(氣). 2. The cause of Peson is in addition to Pehuh Pimo(皮毛) is demaged by heat and cold. Symptoms are alopecia, cough, sputum, fever and chill. In treatment, supply it's Ki. 3. The cause of Pero is it's Ki which is demaged by lie down for a long time or because of anxiety Sang Ryum Hueng Kum(上炎刑金). Symptoms are tachypnea, chest and back pain, cough and sputum. In treatment, supply Sinki(腎氣). 4. In correlation of Pehuh, Peson and Pero, Pehuh is progressed from Kihuh(氣虛), Peson is progressed from Pehuh and Pero is progressed from Peson. 5. The treatment of Lung disease showed by chapter Huhro(虛勞). In early stage, control it's Ki. In middle stage, supply it's Ki. The last stage, supply Sinki(腎氣).

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제2권2호
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• pp.240-244
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• 1999

저자들은 만성설사와 범발성 혈관내 응고 증후군을 동반한 2개월된 남아에서 장병성 선단 피부염을 의심하여 아연을 경구 투여한 후, 증상호전을 보인 장병성 선단 피부염 환아 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• Journal of Korean Neurosurgical Society
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• 제38권3호
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• pp.190-195
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• 2005

Objective : This study is performed to evaluate the procedural complications, aneurysm occlusion rate, and mid-term outcome of endovascular treatments in intracranial aneurysms. Methods : We retrospectively investigated 135 patients with 161 cerebral aneurysms who were treated by endovascular means at our institute from March 1999 to December 2004. We statistically analyzed overall outcome, occlusion rate, and occurrence of complications according to the location, size, rupture history, and neck size of aneurysms. Results : Forty-nine patients [36.3%] had experienced acute intracranial or extracranial complications related to the procedure. Among these, there were 13cases of perforation of the aneurysm, 9 of local vasospasm, 8 of thromboembolism, 4 of coil migration, 3 of occlusion of parent vessels due to coil protrusion, and 1 of seizure. Extracranial complications occurred in 14cases including alopecia [9cases], femoral artery thrombosis [2cases], acute renal failure [2cases], and hypovolemic shock [1case]. One hundred twenty-six aneurysms [78.3%] had complete occlusion of the aneurysm and 35 [21.7%] incomplete occlusion at 6months angiographic follow-up. Postembolization clinical follow-up ranged from 1 to 60months [mean, 14.2months]. Seven of the 161 aneurysms underwent additional embolization and 2 incomplete embolized aneurysms required subsequent surgery. Conclusion : The procedural complications and incomplete occlusion rates are substantial. Therefore, endovascular treatment needs close and continued neurosurgical and neuroradiological concerns for the therapy of intracranial aneurysms.

• 한국임상수의학회지
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• 제35권1호
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• pp.19-21
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• 2018

A 7-year-old female American cocker spaniel presented with chronic regurgitation and megaesophagus on radiography at a local hospital. Dry and coarse hair coat, tail alopecia, and bradycardia were observed during physical examination. Mild, non-regenerative anemia was indicated by complete blood count (CBC) analysis. Concurrent hypercholesterolemia and hypertriglycemia were indicated by biochemistry tests. Decreased levels of total and free thyroxine (T4) and increased canine thyroid stimulating hormone (cTSH) levels were also detected. Megaesophagus was confirmed by radiographic examination. Based on the results, a diagnosis of hypothyroidism with megaesophagus was made. The patient was initially treated with levothyroxine sodium at a dosage of 0.02 mg/kg twice a day. After two weeks of treatment for hypothyroidism, the dilated esophagus returned to its original size and no further regurgitation was observed. No relapse was observed during two months of follow-up.

• 한국임상수의학회지
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• 제36권6호
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• pp.345-348
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• 2019

A four-year old, indoor-living neutered male Old English Bulldog was presented for generalized ulcerative dermatitis. Generalized alopecia and multifocal papules and ulcers with crusting were observed mainly in the dorsal trunk. Cytology of the skin lesions revealed a pyogranulomatous inflammation comprising macrophages and nondegenerate neutrophils. Histopathology also revealed a nodular dermatitis characterized by mixed infiltration of monocytes and neutrophils involving the superficial and deep dermis. Neither of bacteria nor fungus was identified in microscopic exam and culture. From those findings, a diagnosis of cutaneous sterile pyogranuloma/granuloma syndrome (SPGS) was made. Treatment with immunosuppressive drugs of prednisone and cyclosporine was performed and visible ulcerative skin lesions were resolved after 4 weeks of initiation of therapy. Treatment with combination of cyclosporine and prednisone may be effective for the case of SPGS.

• 한국임상수의학회지
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• 제38권5호
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• pp.221-224
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• 2021

A 8-year-old male Golden Retriever dog with bilateral cryptorchidism presented for evaluation of symmetric alopecia and gynecomastia. Abdominal radiography and computed tomography revealed bilateral enlargement of the testicles in the abdominal cavity. The concentrations of estradiol and testosterone in the blood were evaluated, and the results revealed a low testosterone/estradiol ratio despite a normal concentration of estradiol. For correction, cryptorchid testicles were surgically removed. Grossly, the bilateral retroperitoneal cryptorchid testicles were enlarged, firm, and spherical. On histopathologic examination, the right abdominal cryptorchid testicle was diagnosed as a Sertoli cell tumor (SCT)-Seminoma (SEM) combination. The contralateral testicle in the abdomen was diagnosed as a Sertoli cell tumor. The clinical signs of feminization were improved after surgery. To our knowledge, this is the first report of a case of simultaneous SCT on one side and SCT-SEM combination on the other side with sex hormone profiles in a dog.

• International journal of advanced smart convergence
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• 제8권1호
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• pp.184-195
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• 2019

This study investigates the hair restoration efficacy of selected radish saponin extracts on nude mice. Nude mice genetically predisposed to pattern balding were used in this study. Our study revealed the underlying mechanism of stimulating hair growth in athymic nude mice by repair the nu/nu follicular keratin differentiation defect. Thus, the topical application of radish saponin may represent a novel strategy for the management and therapy of certain forms of alopecia. The term of hair density of PEE treated nude mice were significantly increase as compared with of control nude mice. Histological observation of skin sample showed no hair follicle or only distorted hair follicles were observed in the control samples, in contrast, by the PEE treatment groups showed a fully formed and increased the number of hair follicles up to three times higher than that of control group in terms of the number of hair follicles in nude mouse skin.PEE treated mice the number of BrdU-labeled keratinocytes per anagen follicle increased significantly, especially in the follicular bulbs and outer root sheath compared with the control mice. Moreover, PEE-treated nude mice also exhibited a significant increase in the number of BrdU-labeled epidermal keratinocyte proliferation.

• Korea Journal of Cosmetic Science
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• 제1권1호
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• pp.11-18
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• 2019

Caffeine is widely used in cosmetics and hair care products. Although its efficacy in stimulating hair growth has been confirmed in recent studies, its mechanism of action remains unelucidated. The present study aimed to determine the effects of caffeine on hair growth, with a focus on intracellular hair follicle activity. Experiments included in vitro and ex vivo tests, and a clinical study. Caffeine enhanced the cellular activity and potassium channel opening. It also promoted human hair follicle elongation. Immunohistochemical staining showed that the Ki-67 signal was significantly higher in cells treated with caffeine. These efficacies of caffeine were comprehensively demonstrated in clinical results, wherein caffeine-containing shampoo improved hair density after 24 weeks of testing. Collectively, the results of this study demonstrated that caffeine promoted hair growth and inhibited the progression of hair loss by enhancing intracellular activity of hair follicles.