• Journal of radiological science and technology
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• v.14 no.2
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• pp.33-36
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• 1991

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1807-1810
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• 2014

Background: It is known that inducible nitric oxide synthase (iNOS)/nitric oxide (NO) plays an integral role during intestinal inflammation, an important factor for colon cancer development. Natural compounds from Curcuma longa L. (Zingiberaceae) have long been a potential source of bioactive materials with various beneficial biological functions. Among them, a major active curcuminoid, demethoxycurcumin (DMC) has been shown to possess anti-inflammatory properties in lipopolysaccharide (LPS)-activated macrophages or microglia cells. However, the role of DMC on iNOS expression and NO production in an in vitro inflamed human intestinal mucosa model has not yet been elucidated. This study concerned inhibitory effects on iNOS expression and NO production of DMC in inflamed human intestinal Caco-2 cells. An in vitro model was generated and inhibitory effects on NO production of DMC at 65 ${\mu}M$ for 24-96 h were assessed by monitoring nitrite levels. Expression of iNOS mRNA and protein was also investigated. DMC significantly decreased NO secretion by 35-41% in our inflamed cell model. Decrease in NO production by DMC was concomitant with down-regulation of iNOS at mRNA and protein levels compared to proinflammatory cytokine cocktail and LPS-treated controls. Mechanism of action of DMC may be partly due to its potent inhibition of the iNOS pathway. Our findings suggest that DMC may have potential as a therapeutic agent against inflammation-related diseases, especially in the gut.

• Journal of Korean Clinical Health Science
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• v.5 no.4
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• pp.981-990
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• 2017

Purpose: The purpose of the study was to investigate the relationship between job searching efficacy and employment stress of the allied health students. Methods: A self-reported questionnaire was completed by 269 allied health students in Gyeongnam from September to October 30, 2015. The questionnaire consisted of general characteristics of the subjects(5 items), employment stress(22 items), job searching efficacy(27 items). Data were analyzed by SPSS 20. program. Results: In case of the man, good economic level, dissatisfied with major have higher job searching efficacy in allied health students. Department of physical therapy students had higher employment stress. The employment stress has an effect on higher self-esteem, higher employment in information technology, in case of the man, lower career adopted a capability. Conclusions: It is necessary to reduce employment stress of the allied health students. That should be provide support of economical, innovation curriculum development opportunity of self-development on improve the self esteem and employment in information technology, interview skill, writing resume from freshman to broaden understanding of the majors, for the employment stress coping skill.

• Journal of Korean society of Dental Hygiene
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• v.16 no.4
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• pp.643-649
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• 2016

Objectives: The purpose of the study was to investigate the relationship between professor trust and learning flow in allied health students and to provide the basic data for the improvement of curriculum and teaching method. Methods: A self-reported questionnaire was filled out by 263 allied health students. The questionnaire consisted of 27 questions of professor trust by Likert 5 scale and 29 questions of learning flow by Likert 6 scale. Cronbach's alpha in this study was 0.97 in professor trust, 0.96 in learning flow. The data were analyzed using descriptive statistics, independent t-test, one-way ANOVA, correlation and stepwise multiple regressions. Results: The score was 3.72 in professor trust and 3.46 in learning flow. There were positive correlations between learning flow and professor trust including intimacy, professional, teaching skills and leadership. Stepwise multiple regression analysis revealed that learning flow was related with professor trust. Conclusions: The learning flow depends on professor trust. Based on the research, improvement directions that put strong emphasis on low section of professor trust and learning flow must be placed.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.4
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• pp.1289-1295
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• 2012

The use of herbal products as radiosensitizers is a promising approach to increase the efficacy of radiotherapy. However, adverse effects related to the use of herbal medicine on radiotherapy are not well characterized. The present study concerns the impact of Derris scandens Benth extract on the radiosensitivity of Hep-2 laryngeal cancer cells. Pretreatment with D. scandens extract prior to gamma irradiation significantly increased clonogenic survival and decreased the proportion of radiation-induced abnormal nuclei of Hep-2 cells. Furthermore, the extract was found to enhance radiation-induced G2/M phase arrest, induce Akt activation, and increase motility of Hep-2 cells. The study thus indicated that D. scandens extract potentiates radioresistance of Hep-2 cells, further demonstrating the importance of cellular background for the adverse effect of D. scandens extract on radiation response in a laryngeal cancer cell line.

• Child Health Nursing Research
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• v.26 no.4
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• pp.463-469
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• 2020

Reduction of the under-5 mortality rate is a target of the Sustainable Development Goals. Therefore, this study aimed to estimate under-5 child mortality rates in 52 low-migration countries using population data. The study utilized population data from the US Census Bureau from 1990 to 2015. The method involved first estimating mortality rates for countries with negligible net migration and then applying these rates to countries with matching mortality profiles, where it is reasonable to assume that migration is negligible for children under the age of 5 years. The highest child mortality was concentrated in the African region, followed by Asia and the Western region. However, steady progress in child mortality trends was concentrated in low-income countries. This simple method demonstrated that child mortality has significantly improved in high-income countries, followed by middle- and low-income countries. To reduce the under-5 mortality rates even further in these 52 countries, there is a need to accelerate equitable plans and policies related to child health to promote children's longevity and survival.

• Journal of radiological science and technology
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• v.14 no.1
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• pp.73-93
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• 1991

• Journal of radiological science and technology
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• v.15 no.2
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• pp.83-86
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• 1992

• Journal of Korean society of Dental Hygiene
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• v.16 no.2
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• pp.261-268
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• 2016

Objectives: The purpose of this study is to investigate the awareness and needs of English learning in allied health science college students. Methods: A self-reported questionnaire was filled out by 600 health science college students in Seoul, Gyeonggi and Incheon province. The questionnaire consisted of purpose of English learning, attitude and motivation. Data were analyzed by SPSS 19.0 program. Results: Most of the students took English classes(96%) and the English class was mainly done by instruction-centered learning (43.6%). Many students felt the needs of English and they thought English was the most important tool for getting a job(70.7%). Nonetheless most of the students lacked in confidence and interest in English learning due to the surrounding pressure(51.2%). Too much surrounding pressure can cause students lose their zest in English learning. Conclusions: It is need to seek for a curriculum consisting of practical purposes to meet the needs of health science college students about English learning.

• Journal of radiological science and technology
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• v.17 no.2
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• pp.51-56
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• 1994