• Journal of Acupuncture Research
• /
• 제20권3호
• /
• pp.166-176
• /
• 2003

Objective : The aim of this study is to investigate the anti-inflammatory effects of 15Hz electroacupuncture(EA) on carrageenan-injected rats. Inflammation was induced by an intraplantar injection of 1% carrageenan into the right hind paw. Methods : Bilateral EA stimulation with 15 Hz were delivered at those acupoints corresponding to Zusanli and Sanyinjiao in man via the needles for a total of 30 min duration in carrageenan-injected rats. Results: The developing edema was measured 30 minutes interval afer carrageenan injection and 15 Hz EA stimulation presented significant edema inhibition. Three hours after carrageenan injection, prostaglandin $E_2(PGE_2)$ and nitric oxide(NO) levels were measured. The 15Hz EA stimulation significantly inhibited $PGE_2$ and NO production in the right paw. The pro-inflammatory mRNA expression such as cyclooxygenases(COX)-2 and interleukin(IL)-$1{\beta}$ were slightly down-regulated by EA stimulation. The number of COX-2, IL-$1{\beta}$, tumor necrosis factor-${\alpha}$ immunoreactive cells were abundantly observed in paw edema. But these cells were decreased in nmber according to anti-edema effect of 15Hz EA. Conclusions: These results indicate that 15Hz EA stimulation have an alleviation action against carrageenan-induced edema and local inflammation.

• Biomolecules & Therapeutics
• /
• 제10권3호
• /
• pp.137-141
• /
• 2002

Taurine, amino acid, chemically known as 2-amino ethane sulphonic acid was discovered more than two hundred years ago from ox bile. it is widely distributed in both mammals and nonmammals. It is found in considerably high amount in hUl11an: a normal adult of 70 kgs contains about 70 grams of taurine. Taurine with this much concentration, is involved in almost all life processes. Its deficiency causes several abnormalities in major organs like brain, eye and heart. Taurine-bone interaction is latest addition to its long list of actions. In bone cells, taurine is also found in high concentration. Taurine is found to help in enhancing the bone tissue formation which is evidenced by increased matrix formation and collagen synthesis. Besides stimulating the bone tissue formation, it also inhibits the bone loss through inhibiting the bone resorption and osteoclast formation. Thus, taurine acts as a double agent. In addition to these two major actions of taurine in bone, it also has beneficial effect in wound healing mld bone repair. Taurine possess radioprotective properties, too. As it is a naturally available molecule, it can be used as a preventive agent. Taurine has a potential to replace bisphosphonates which are currently in use for the inhibition of bone loss but this needs in depth study. As taurine is involved in bone formation and inhibition of bone loss, a detailed study can make it a single marker of bone metabolism. All these taurine-bone interaction is a symbol of their deep involvement but still require further extension to make taurine as a choice for tile sound bone health.

• The Journal of Korean Physical Therapy
• /
• 제20권1호
• /
• pp.23-31
• /
• 2008

Purpose: The purpose of this study was finding out the effects of spinal stabilization exercise using Centaur which is a 3D spinal stabilization sports implement on Chronic low back pain patients over 8 weeks. Methods: 30 patients with DDD were observed during the study. Their average age was 66.88years, height was 152.12cm and average weight was 58.91kg, 4 males and 26 females were involved. 8 various investigations were performed and varied values were compared with reinvestigation done after having exercised 8 weeks using 3-D CENTAUR We used VAS(visual analog scale) in order to see the variation of pain intensity, MOI(modified oswestry index) in order to see limitation of daily life. Results: VAS was lessened from 7.57 to 2.63, limitation of routine life(MOS) from 23.48 to 11.30, there were remarkable differences statistically(p<0.05). As a result of muscular investigation for static spinal stabilization by 8 variations of body deflection, muscular strength were all increased and there were signigicant differences statistically(p<0.05). Conclusion: It has turned out that pain and limitation of routine life was lessened, as a result of 8 weeks exercise using CENTAUR, and deep muscular power was increased. Thus it has turned out that 3-D spinal stabilization exercise has an effect on the strengthening spinal muscles and alleviation of their pain for old patients with DDD.

• The Journal of Asian Finance, Economics and Business
• /
• 제7권10호
• /
• pp.73-85
• /
• 2020

As an effort to achieve sustainable development and increase people's welfare, financial inclusion has become the policy agenda of many countries. Therefore, the effect of financial inclusion on economic growth, poverty, income inequality, and financial stability in several countries in Asia has become the goal and this is the subject of this study. Financial inclusion is measured by 3 dimensions, namely banking penetration, access to banking services, and use of banking services. Poverty ratio below the national poverty line and the Gini coefficient are used as indicators of poverty and income inequality. Financial stability is measured by Bank Z-Score and bank nonperforming loans. The results from the hypothesis test shows that all dimensions of financial stability simultaneously have significant influence on economic growth, poverty, income inequality, and financial stability. On the other hand, the partial impact of financial inclusion dimension on economic growth, poverty alleviation, income inequality, and financial stability in ten countries of Asia has not been optimal. The derived results of this study is required to be interpreted and considered by the Governments of each country in developing strategies for increasing financial inclusion, so that the policy to achieve sustainable development and enhancement of people's welfare can be achieved.

• Journal of Dental Anesthesia and Pain Medicine
• /
• 제16권1호
• /
• pp.25-29
• /
• 2016

Background: The most important reason for pre-operative administration of medication is to reduce anxiety. Alleviation of fear and anxiety about surgery enables patients to remain comfortable during treatment. Dexmedetomidine (DEX) is a fast-acting drug that is used as a premedication in different circumstances because it has sedative and anti-anxiolytic effects, and stable hemodynamics. It also has the advantage of intranasal administration. The aim of this study was to investigate the effects and hemodynamic stability of DEX by retrospectively analyzing cases in which DEX was administered nasally as a premedication. Methods: Ten patients treated at Dankook University Dental Hospital, recruited between February and April 2015, received intranasal delivery of $2{\mu}g/kg$ DEX, 30 minutes prior to general anesthesia. Anesthesia records of anxiety, blood pressure, respiration, pulse, estimated arterial oxygen saturation ($SpO_2$), and partial pressure, or maximum concentration, of carbon dioxide ($ETCO_2$) were analyzed. Results: Administration of DEX prior to a general anesthetic effectively relieved anxiety. Respiratory depression, the most severe adverse effect of other sedatives, was not observed. Hemodynamic stability under general anesthesia was maintained during treatment and a reduction in emergence delirium was observed upon completion of treatment. Conclusions: Premedication administration of DEX is safe for pediatric patients undergoing dental treatment under general anesthesia.

• 부모자녀건강학회지
• /
• 제10권1호
• /
• pp.48-64
• /
• 2007

Purpose: The purpose of this study is to identify the effectiveness of Qi exercise on the physical discomfort and depress of maternity. Method: A one group pretest-posttest design was used. Data were collected from July, 1, 2005 to September, 30, 2005. A total of 33 mothers participated in 12 weeks of Qi exercise program. In order to evaluate the effects of the Qi exercise program, physical discomfort and depression were measured before and 12 weeks after. The experimental tools for the study were Maternity Physical discomfort Scale and Self-rating Depression Scale(SDS). Data were analysed using t-test, paired t-test, and repeated measured ANOVA on the SPSS program. Result: After 12-week Qi exercise program, there were significant differences in physical discomfort (t=3.268, p= .003) and depression(t=4.106, p= .000). Conclusion: It was verified that the Qi exercise program was effect on relieving physical discomfort and depression scare. And it was effective in alleviation delivery experience score. So more in-depth research is needed later on.

• 한국태양에너지학회 논문집
• /
• 제28권2호
• /
• pp.50-57
• /
• 2008

This study intends to evaluate the effect on indoor environment(annual thermal load, sunshine)by the application of the movable horizontal shading device on summer and winter season. For these purpose, we supposed the models which are composed of the several horizontal shading devices. Then we analyzed the simulation using the IES5.5.1 and Seoul weather data. The results of this study are as follows: 1) The proper length, angle of horizontal shading device is 2.1m, 28 degree, respectively. 2) The decreasing rate of the annual load of the Movable Horizontal Shading Model(MHSM) in comparison with the No Shading Model(NSM) & Conventional Horizontal Shading Model(CHSM) is 31.11%, 6.63% respectively. 3) The decrease of sunshine of the MHSM on summer season is effective the alleviation of visual displeasure. On the other hand, the increase of sunshine of the MHSM on winter season is effective the psychological comfort. Further study is to be required the sensitivity analysis on the various shading length for the realistic proper shading length.

• 전기학회논문지
• /
• 제65권8호
• /
• pp.1392-1399
• /
• 2016

Blackout effect occurs when a driver misadapts to the changed lighting conditions upon entering a tunnel. This could lead to a decrease in visibility especially in the daylight, depending on the difference in the degree of brightness between inside and outside the tunnel. To alleviate such a problem, we decrease windshield transparency before the driver arrives at the tunnel entrance. Controlled amount of light inside the car can allow the drivers to adjust to the dark prior to entering. The windshield transparency coefficient is to be determined by the arrival time at the tunnel and difference in the level of brightness between inside and outside the tunnel. Navigation, road sign detection, and tunnel entrance detection provide the arrival time. We also designed an opto-electronic conversion function to estimate the level of brightness. The black-hole phenomenon alleviation method is verified by field experiments using an automobile camera and a navigation. The result shows that the adjusted windshield transparency is able to provide an environment with a comfortable level of brightness with which the drivers can enter tunnels without the visibility problem.

• Journal of Dairy Science and Biotechnology
• /
• 제37권2호
• /
• pp.94-101
• /
• 2019

Probiotics stabilize intestinal microflora, reduce constipation, reduce decay by inhibiting harmful bacteria, and prevent diseases. Probiotics have also been studied for their possible roles in immune activation, treatment of cancer, remediation of cholesterol, treatment of diabetes, alleviation of allergies, and relief of lactose intolerance. However, recent data concerning the side effects of probiotics have prompted debate regarding their efficacy and safety. Major adverse events associated with probiotics are gastrointestinal symptoms, such as diarrhea, gastrointestinal disorders, and vomiting, along with skin rash and urticaria. Probiotics occasionally cause sepsis in infants with poor immunity and elderly people with severe diseases. In contrast to previous studies that described the efficacy of probiotics in intestinal regulation, some recent studies have reported that the activity of intestinal microbes becomes weak as a result of the influx of probiotics. The data indicate that the safety of probiotics is not guaranteed and that further investigations are needed.

• 대한한방내과학회지
• /
• 제40권3호
• /
• pp.557-565
• /
• 2019

Objectives: This study investigated the effect of local acupuncture point stimulation and the application of a topical herbal mixed heating cream in a chronic cough patient who had not responded to various medications for more than a few months. Methods: An 81 year-old female patient who was suspected to be suffered from Upper Airway Cough Syndrome (UACS) was examined. The patient was treated with local acupuncture point stimulation and the application of a topical herbal mixed heating cream. We used the Leicester Cough Questionnaire, Cough-Specific Quality-of-Life Questionnaire, and Verbal Numerical Rating Scale to assess the patient's respiratory symptoms. Results: Local acupuncture point stimulation and the application of a topical herbal mixed heating cream resulted in the improvement of cough symptoms. The quality of life due to the alleviation of symptoms also significantly improved. Adverse effects were not observed. Conclusions: This study suggests that local acupuncture point stimulation and the application of a topical herbal mixed heating cream may be an effective therapy for the treatment of chronic cough in patients with UACS.