• Title/Summary/Keyword: Alleviation effect

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Analysis of Studies on Ssanghwa-tang for Establishment of Evidence Based Medicine (EBM 구축을 위한 쌍화탕의 실험 연구 문헌 분석)

  • Lee, Jun-Kyoung;Lee, Nam-Hun;Ha, Hye-Kyoung;Lee, Ho-Young;Seo, Chang-Sub;Jung, Da-Young;Lee, Jin-Ah;Shin, Hyun-Kyu
    • Korean Journal of Oriental Medicine
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    • v.14 no.3
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    • pp.41-47
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    • 2008
  • Objective : The purpose of this report was to provide the information about activity and safety of Ssanghwa-tang by analyzing domestic papers and theses about Ssanghwa-tang. Methods : Domestic papers and theses related to Ssanghwa-tang were reviewed and analyzed. These papers were then classified by year, experimental method, and activity subject. Results : The following result s were obtained in this study. 1. The study of Ssanghwa-tang started from 1981 and continued steadily 1990s and it was decreased 2000s. 2. The paper of Ssanghwatang was entire domestic paper, 20 volumes. 3. In classified by experimental method and animal of Ssanghwa-tang paper, more than a half study used rat in vivo experiment. Furthermore clinical experiments were performed about anti-fatigue effect of Ssanghwa-tang and Ssanghwatang was proved a safety herbal medicine in acute toxicity experiment. 4. Decursin, glycyrrhizin, paeoniflorin were determined in Ssanghwa-tang by using HPLC analysis. 5. As these studies were classified by subject, papers related to anti-fatigue effect were most abundant by 7 papers. Besides there were several papers related to liver funtion, anti-inflammatory, alleviation, smooth muscle relaxation effect and so on. 6. According to experimental data, it is supported that Ssanghwa-tang was safety herbal medicine and it has a several activity about anti-fatigue, anti-inflammatory, alleviation, smooth muscle relaxation. Conclusion : Many study of basic science experiments and clinical experiments were performed and reported on Ssanghwa-tang in domestic journal. Ssanghwa-tang is being used in various ways associating with anti-fatigue, anti-inflammatory, alleviation and smooth muscle relaxation. furthermore Ssanghwatang was proved a safety herbal medicine in acute toxicity experiment. However, studies on randomized controlled trials of Ssanghwatang need to be completed at the clinical level.

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Effects of Low Dose Gamma-irradiation on Alleviation of Salt Stress in Rice (Oryza sativa L.) Seedling (저선량 감마선 조사가 벼 유묘의 염 스트레스 경감에 미치는 영향)

  • Baek, Myung-Hwa;Kim, Jin-Hong;Wi, Seung-Gon;Lee, In-Jung;Lee, Kyu-Seong;Kim, Jae-Sung
    • Korean Journal of Environmental Agriculture
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    • v.24 no.2
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    • pp.153-158
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    • 2005
  • To investigate alleviation effects of salt stress by low dose gamma-irradiation on seedling growth of rice (Oryza shrive L), in plants of two rice cultivars (Ilpumbyeo and Gancheokbyeo), seeds were irradiated with the different doses $(0{\sim}32\;Gy)$ of gamma-ray by irradiator ($^{60}Co$, ca.150 TBq of capacity, AECL). The salt stress caused a remarkable decrease of seedling growth, particularly for dry weight. In addition, relative growth rate was decreased over 50% by the salt stress. However, the salt stress-induced inhibition of growth was alleviated by gamma-irradiation. Especially, the relative growth rate of shoot showed the reduction effect over 30% at 4 Gy-irradiated groups as compared with that of control. Also, electrolyte leakage and relative water content were damaged, respectively 4 times and 30% by the salt stress but the damages were alleviated by the gamma-irradiation. These alleviation effects were observed similarly in both the cultivars tested. These results suggest that the low dose gamma-irradiation may have a better protection or the salt stress.

Antioxidant and Anti-Obesity Activities of Polygonum cuspidatum Extract through Alleviation of Lipid Accumulation on 3T3-L1 Adipocytes

  • Choi, Da-Hye;Han, Joon-Hee;Yu, Keun-Hyung;Hong, Min;Lee, Sun-Yeop;Park, Ka-Hee;Lee, Soo-Ung;Kwon, Tae-Hyung
    • Journal of Microbiology and Biotechnology
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    • v.30 no.1
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    • pp.21-30
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    • 2020
  • Natural products are widely used due to their various biological activities which include anti-inflammatory, antioxidant, and anti-obesity effects. In this study, we determined the antioxidative and anti-obesity effects of Polygonum cuspidatum 50% ethanol extract (PEE). The antioxidative effect of PEE was evaluated using its radical scavenging activity, total phenolic content, and reducing power. The anti-obesity effect of PEE was investigated using 3T3-L1 adipocytes. The antioxidative activity of PEE was progressively increased in various concentrations, mainly due to the presence of phenolic compounds. PEE also alleviated lipid accumulation on 3T3-L1 adipocytes and downregulated the mRNA and protein production of adipogenesis-related (SREBP-1c, PPARγ, C/EBPα) and lipogenesis-related (aP2, FAS, ACC) markers. Furthermore, we found that the inhibitory effect on lipid accumulation via PEE was caused by the alleviation of NF-κB, p38 MAPK, ERK1/2, and JNK at the protein level. Taken together, our results imply that PEE is a potential antioxidant that can prevent obesity-associated disorders.

An Assessment of the Quantitative Effect of TSS by Vessel Traffic Flow Simulation (해상교통류 시뮬레이션을 이용한 통항분리제도의 정량적 효과평가)

  • ;;;INOUE, Kinzo
    • Journal of Korean Society of Transportation
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    • v.21 no.1
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    • pp.41-49
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    • 2003
  • Marine traffic management could be defined as the implementation of managerial technical measures to improve vessel traffic safety. The managerial elements of vessel traffic management for ports and harbours or narrow channels include the total amount of traffic control, the vessel traffic separation scheme, speed restriction, traffic control by signals, the navigation information service and so forth. This research aims to quantify how much the traffic separation schemes(TSS) contribute to the alleviation effect of ship handling difficulty and to propose a design standard when the individual management measure is applied in an actual waterway. Traffic separation schemes have now been established in most of the major routes and congested waters of the world, and the number of collisions and groundings have often been dramatically reduced. In this part, the relationship between the alleviation of ship handling difficulty and the reduction of encounter figures among ships is quantitatively clarified by applying the ES model. As results of simulation analysis, it is recognized that a traffic separation system is most effective in the case of narrow width and heavy traffic volume. The centre buoy installation reduces about 1/4 of the alleviation of ship handling difficulty, TSS establishment 1/3, and design change to one-way traffic from two-way traffic reduces 1/2.

Effect of Increased Water Intake on the Alleviation of Heat Stress in Chicken (수분 섭취의 증가가 닭의 고온 스트레스 완화에 미치는 효과)

  • 이봉덕
    • Korean Journal of Poultry Science
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    • v.21 no.2
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    • pp.93-99
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    • 1994
  • Chickens subjected to heat stress decrease their heat production by consuming less feed. The lowered feed intake naturally brings about decreased production performance of chicken. The only exception to this is the increased survivability. Birds drink less when they eat less. In hot enviror-mental temperature, chicken need more water for increased heat loss through evaporation an increased urine excretion. Thus, the increased water intake may alleviate the heat stress of chicken. Various electrolytes supplementation to feed or drinking water can alleviate the heat stress of chicken by their effect of increasing water intake. Lasalocid, an ionophorous coccidiostat, was found to have the effect of increasing water consumption of chicken, thereby improving the lowered production performance of heat-stressed chicken. Finally, dietary fiber could be another possible element which can exert beneficial effects on heat-stressed chicken.

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An Exploration of Players' Aggression: Role of Game and Life Self-Efficacy and Adaptive Game Use Tendency

  • Lee, Hye Rim;Jeong, Eui Jun
    • International Journal of Contents
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    • v.11 no.4
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    • pp.7-14
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    • 2015
  • This study examined whether game usage would alleviate players' aggressive tendencies. Other game-related variables, psychological care factors (adaptive game use tendency, game self-efficacy, and life self-efficacy), and psychological problem factors (loneliness and depression) were controlled for determination of the effect. We drew on the catharsis theory from therapeutic psychology literature to explain how game usage contributes to the alleviation of aggressive tendencies. Over two weeks data were collected from 918 participants online. The results indicated that gaming activity had a significant effect on aggression. Higher levels of game and life self-efficacy, as well as adaptive game use tendencies, decreased the degree of aggression. Likewise, higher levels of loneliness and depression reduced the degree of aggression. Results and implications are discussed.

Performance Analysis of Array Processing Techniques for GNSS Receivers under Array Uncertainties

  • Lee, Sangwoo;Heo, Moon-Beom;Sin, Cheonsig;Kim, Sunwoo
    • Journal of Positioning, Navigation, and Timing
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    • v.6 no.2
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    • pp.43-51
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    • 2017
  • In this study, the effect of the steering vector model mismatch due to array uncertainties on the performance of array processing was analyzed through simulation, along with the alleviation of the model mismatch effect depending on array calibration. To increase the reliability of the simulation results, the actual steering vector of the array antenna obtained by electromagnetic simulation was used along with the Jahn's channel model, which is an experimental channel model. Based on the analysis of the power spectrum for each direction, beam pattern, and the signal-to-interference-plus-noise ratio of the beamformer output, the performance deterioration of array processing due to array uncertainties was examined, and the performance improvement of array processing through array calibration was also examined.

Four cases of Seborrheic Dermatitis treated by Fermented Yungyo Keumeunhwa Extract External treatment Liquid (발효된 연교금은화 추출물 외치액을 병행한 지루성 피부염 치험 4례)

  • Kim, Ki-Bae;Kim, Tae-Wook;Choi, Sung-Hee
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.26 no.4
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    • pp.101-110
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    • 2013
  • Objectives : The purpose of this study is to report the effect of Fermented Yungyo Keumeunhwa Extract External treatment Liquid on Seborrheic Dermatitis. Methods : Four Seborrheic Dermatitis patients on the face of each Diluted Yungyo Keumeunhwa Extract External treatment Liquid patch was 10 minutes. Results : The Fermented Yungyo Keumeunhwa Extract External treatment Liquid was effective on alleviation of symptoms like flare, scale, uredo and pricking on Seborrheic Dermatitis. Conclusions : The result indicate that Fermented Yungyo Keumeunhwa Extract External treatment Liquid has an available effect on Seborrheic Dermatitis, and authors consider that the additional clinical studies are needed to verify the effectiveness of monotherapy.

An Analysis of Delayed Voltage Recovery Phenomenon according to the Characteristics of Motor Load in Korean Power System (모터부하 특성에 따른 국내 전력계통의 전압 지연 회복 현상 분석)

  • Lee, Yun-Hwan
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.65 no.3
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    • pp.178-182
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    • 2016
  • FIDVR(Fault Induced Delayed Voltage Recovery) is a phenomenon that recovery of the system voltage level delays after the fault. Cause of FIDVR phenomenon is motor load characteristic about voltage and reactive power. In low voltage condition, the motor go to stall state that consume large amount of reactive power. As a result, the voltage recovery problem is that of repeated occurrences of sustained low voltage following faults on the system. In this paper, analysis the characteristics of the motor load. And using the korean power system actual data, perform a case studies to voltage delay recovery phenomenon alleviation method. Change of each parameters by analyzing the effect on system and selecting an influence parameter. In addition, dynamic characteristic analysis of the resulting difference in the proportion by the motor load in power systems, considering the effect on the voltage stability.

An Experimental Studies on the alleviation effects of Daebangpoongtang(大防風湯) in LPS-induced arthritis (대방풍탕(大防風湯)의 LPS유발(誘發) 관절염(關節炎) 완화효과(緩和效果)에 관한 실험적(實驗的) 연구(硏究))

  • Jeon, Won-June;Shin, Gil-Jo;Lee, Won-Chul
    • The Journal of Dong Guk Oriental Medicine
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    • v.9
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    • pp.35-49
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    • 2000
  • Purpose: This study is to investigate the alleviation effects of Daebangpoongtang in LPS induced arthritis in mice knee joint. Methods : Daebangpoongtang was chosen to treat the arthritis caused by injecting $300{\mu}g/kg$ LPS to mice knee joint. The control group had no treatment, while the LPS group was injected $300{\mu}g/kg$ LPS to mice knee joint and the DBP group was oral administrated of Daebangpoongtang. After injection of $300{\mu}g/kg$ LPS to mice knee joint, the alteration of synovial lining cell, vessel, fibrosis, distribution of collagen fiber, fibroblast, mast cell, infiltration of inflammation component cell and distribution of ICAM and VCAM was observed by light microscope(BX50). Results : In the DBP extract treatment group, the distribution of vessel, the enlargement of synovial lining cell layer, the synovial lining cells with filopodia, the fibrosis, the distribution of fibroblast in synovial membrane, the distribution of TCAM and VCAM on the knee joint was less than that of LPS group. Infiltrated lymphocyte into the apical surface had not observed in the DBP extract treatment group. The distribution of mast cell was as same as control group(no treatment group) and it showed granulated type. Conclusion: According to the above results, it might be considered that the administration of Daebangpoongtang has a curative effect on synovial membrane injury in arthritis by inhibiting increase of vessel, cell adhesion molecule(ICAM and VCAM) in LPS induced arthritis.

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