• The Korean Journal of Pain
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• 제35권1호
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• pp.66-77
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• 2022

Background: Thrombospondin-4 (TSP4) upregulates in the spinal cord following peripheral nerve injury and contributes to the development of neuropathic pain (NP). We investigated the effects of cyanocobalamin alone or in combination with morphine on pain and the relationship between these effects and spinal TSP4 expression in neuropathic rats. Methods: NP was induced by chronic constriction injury (CCI) of the sciatic nerve. Cyanocobalamin (5 and 10 mg/kg/day) was administered 15 days before CCI and then for 4 and 14 postoperative days. Morphine (2.5 and 5 mg/kg/day) was administered only post-CCI. Combination treatment included cyanocobalamin and morphine, 10 and 5 mg/kg/day, respectively. All drugs were administered intraperitoneally. Nociceptive thresholds were detected by esthesiometer, analgesia meter, and plantar test, and TSP4 expression was assessed by western blotting and fluorescence immunohistochemistry. Results: CCI decreased nociceptive thresholds in all tests and induced TSP4 expression on the 4th postoperative day. The decrease in nociceptive thresholds persisted except for the plantar test, and the increased TSP4 expression reversed on the 14th postoperative day. Cyanocobalamin and low-dose morphine alone did not produce any antinociceptive effects. High-dose morphine improved the decreased nociceptive thresholds in the esthesiometer when administered alone but combined with cyanocobalamin in all tests. Cyanocobalamin and morphine significantly induced TSP4 expression when administered alone in both doses for 4 or 14 days. However, this increase was less when the two drugs are combined. Conclusions: The combination of cyanocobalamin and morphine is more effective in antinociception and partially decreased the induced TSP4 expression compared to the use of either drug alone.

• Journal of Ginseng Research
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• 제4권2호
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• pp.146-164
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• 1980

In this paper it was attempted to observe the effect of defatted panax ginseng supplement of the growth rate, feed and protein efficiency ratios, and the contents of cholesterol, total lipid and protein in the serum, liver and aorta in Sprague-Dowley Albino male rat (weighing 83 ${\pm}$ 4 g). Seven kinds of experimental diets were prepared as follows : Stock (control) diet, ginseng control diets supplemented with 0.5, 1.0 and 3.0% of ginseng powder to the stock diet, and defatted ginseng Powder diets supplemented with 0.5, 1.0 and 3.0% of defatted ginseng powder to the stock diet. .All diets contained same level of lipid and protein, respectively. The results obtained are as follows : 1. The growth rate in the feeding group of 0.5% defatted ginseng powder diet for 16week were higher than other diet groups. 2. Feed and Protein efficiency in 0.5% defatted ginseng group showed similar tendency to that in body growth rate. 3. The total cholesterol contents in the serum of 0.5% defatted ginseng Powder diet$.$ group showed the tendency to decrease gradually for 4 to 12 weeks, maintaining higher level than other groups. The free cholesterol contents in the serum of defatted ginseng powder diet group in 8 the and 16th weeks were higher than all ginseng control diet group. The total and free cholesterol contents in the liver of all defatted ginseng diet groups in 16th week were higher than hose of all ginseng control groups. The total cholesterol content at 12h week and the free cholesterol content at 16th week i n the aorta of all defatted ginseng diet groups were lower than those of ginseng control groups, respectively. 4. The total lipid contents in the serum of 1.0 and 3.0% defatted ginseng diet groups at 2nd to I2th weeks were lower than other groups, and those in the liver and aorta of all defatted ginseng diet groups at 12th weeks were lower than those of ginseng control diet groups. 5. The protein contents of the serum and aorta were continuously increased throughout whole experimental period in all experimental groups. The protein content of the liver of all groups were decreased at 2nd week and after then no change was observed.

• Journal of Periodontal and Implant Science
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• 제24권2호
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• pp.340-356
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• 1994

The purpose of this study was to assess the clinical and microbiological effect of chlorhexidine rinse and supragingival plaque control following scaling and root planing on adult periodontal disease. 14 patients with adult periodontitis were selected for the study . They had not taken antibiotics for 6 months and history of dental treatment for 6 months before the study. Patients received a supragingival scaling and root planing under local anesthesia, plaque control group was subjected to professional plaque control 2 times for a period 2 week, chlorhexidine rinse group were subjected to twice daily 0.2% chlorhexidine rinse for a period 2 week. Clinical examination (plaque index, gingival index, probing pocket depth) and distribution of the bacteria morphology of subgingival plaque were monitored on baseline (0 week), 1 week, 2 week, 4 week and 6 week. The results were as follows : 1. Plaque index in chlorhexidine rinse group , plaque control group and control group was significantly reduced during all weeks (P<0.05). 2. Probing pocket depth was significantly reduced at 2, 4, 6 week (P<0.05) in chlorhexidine rinse group and control group, plaque control group was significantly reduced during all weeks (P<0.05). 3. Gingival index was significantly improved at 2, 4, 6 weeks(P<0.05) in chlorhexidine group and plaque control group, control group was significantly improved at 1, 2, 4 weeks (P<0.05). 4. Percentage of cocci was significantly increased at 1, 2, 4 and 6 weeks in chlorhexidine rinse group and control group, plaque control group was significantly increased at 2, 4 and 6 weeks(P<0.05). 5. Percentage of non-motile rods in all group were not significantly changed when compared with those of baseline (0 week) (P<0.05). 6. Percentage of motile rods was significantly reduced during all weeks (P<0.05) in chlorhexidine rinse group, plaque control group was significantly reduced at 2, 4, 6 weeks and 1, 2 and 4 weeks in control group. 7. Percentage of spirochetes was significantly reduced during all weeks (P<0.05), plaque control group was significantly reduced at 2, 4, 6 weeks and 1, 2, 4 weeks in control group. This results were suggested that clinical and microbiological effect of chlorhexidine rinse and supragingival plaque control following scaling and root planing on periodontal disease

• Journal of the Optical Society of Korea
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• 제6권4호
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• pp.165-171
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• 2002

By using a semiconductor optical amplifier and a cross-phase modulation wavelength converter, fundamental all-optical logic gates including NOT, AND, NOR, XOR, and XNOR have been newly proposed and implemented. Realization of these all-optical logic gates will bring up not only all-optical networks but also all-optical computing and signal processing.

• The Journal of Korean Obstetrics and Gynecology
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• 제19권4호
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• pp.148-158
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• 2006

Purpose : Sanhupung(産後風) is not completed golden standards of diagnosis therefore doctors diagnose through symptoms and signs of patients in clinic same as progress of treatments. We polled oriental gynecologic specialists and non-specialisst to find out cognitive differences on Sanhupung. Subjects : We surveyed 83 specialists and 87 non-speciailist from May 15 2005 to Oct 15. We analyzed the result of respondants, 39 (47%) specialists and 65 (75%) nono-specialits). Methods : We sorted all symptoms in previous studies then we categorized them into 4 fields. The results are analyzed by frequency, importance and impact(frequency percentage${\times}$average importance). Results : Except back pain, all pain symptoms were lower evaluated in non-specialist on frequency. Except inguinal region pain, pain of lower limbs and back pain, all pain symptoms were lower evaluated in non-specialist on importance. Except the numbness of limbs, all items of whole body were lower evaluated in non-specialist on frequency. Except edema, numbness of hand and foot and discharge from the uterus, all items were lower evaluated in non-specialist on importance. All items of neuropsychotic symptoms were lower evaluated in non-specialist on frequency and importance.

• Journal of Korean Academy of Nursing
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• 제3권3호
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• pp.73-77
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• 1973

A study on the nutritional status for school-children has been carried out 1,700 school- children of Song-do primary school located in Song-do beach, Busan, Korea, from November to-December, 1972. The evaluation of the nutritional status has been carried out through skin-fold thickness and hemoglobin. The summarized results were as follows. : 1. Skinfolds thickness 1) Subcellular skinfolds thickness . Among boys, that was 3.5mm in the age 6 and 5.4mm in the age 11 Among girls, that was 4.2mm in the age 6 and 7.6mm in the age 11. Girls were thicker than toys in the all age. 2) Upper-arm skinfolds thickness Among boys, that was 5.0mm in the age 6 and 6.8mm in the age 11. Among girls, that was 6.2mm in the age 6 and 8.7mm in the age 11. Girls were thicker than toys in the all age. 3)Abdominal skinfolds thickness. Among boys, that was 4.0mm in the age 6, and 6.4mm in the age 11. Among girls that was 4.0mm in the age 0, and 8.4mm in the age 11. Girls were thicker than boys in the all age. 2. Hemoglobin Proportional range of hemoglobin were observed as 12.2-12.8 gm/㎗.

• Bulletin of the Korean Chemical Society
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• 제11권4호
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• pp.328-331
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• 1990

Three crystal structures of dehydrated Cd(II) and Rb(I) exchanged zeolite A, $Cd_{4.0}Rb_{4.0}-A (a = 12.204(3) {\AA}), Cd_{5.0}Rb_{2.0}-A (a = 12.202(1) {\AA}),$ and $Cd_{5.95}Rb_{0.1}-A (a = 12.250(2) {\AA}),$ have been determined by single-crystal X-ray diffraction techniques. Their structures were solved and refined in the cubic space group Pm3m at $21(1)^{\circ}C.$ All crystals were ion exchanged in flowing streams of mixed $Cd(NO_3)_2·4H_2O$ and $RbNO_3$ aqueous solution with total concentration of 0.05 M. All crystals were dehydrated at ca. $450^{\circ}C$ and $2×10^{-6}$ Torr for 2 days. In all of these structures, $Cd^{2+}$ ions are found on threefold axes, each nearly at the center of a 6-oxygen ring. The first three $Rb^+$ ions per unit cell preferentially associate with 8-oxygen rings, and additional $Rb^+$ ions, if present, are found on threefold axes in the large cavity. The final $R_1$ and $R_2$ values for the three structures are 0.087 and 0.079, 0.059 and 0.067, and 0.079 and 0.095, respectively.

• Journal of Fashion Business
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• 제17권5호
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• pp.120-137
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• 2013

Nowadays, due to the increase of the aging population and the decreased size of the traditional nuclear family, pet dogs are considered to be important member of the family. The pet industry has been growing every year; subsequently, is essential to develop practical patterns and designs which are appropriate for the structure and movement of pet dogs. However, studies for developing a new form of pet dog's wear patterns and designs are limited. This study develops an all-in-one pattern which is based on pet dog's size, designs pet dog's wear items based on all-in-one patterns, and provides support to the manufacture of pet dog's wear. The results are as follow: 1) An analysis for the categories and design characteristics of all-in-one pet dog's wear according to the research from the online pet dog's wear shopping sites is provided. Eight categories are classified as follows: rompers, body suit, coveralls, training suit, special clothing, overalls, rain coat, and hanbok. 2) The production of all-in-one pet dog's wear basic pattern based on the basic bodice pattern from the prior studies and the manufacturer's patterns are being displayed. 3) Developments of the patterns and designs for eight all-in-one clothing consider the design characteristics and the situations. 4) Developments of the previous eight items illustrate the results of this research.

• Restorative Dentistry and Endodontics
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• 제16권2호
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• pp.126-142
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• 1991

The purpose of this study was to evaluate the effect of various dentin surface treatments on shear bond strength, microhardness and fracture mode before and after thermocycling. Recently extracted 75 human molars were used. The teeth were sagittal sectioned faciolingually to obtain 150 specimens. They were randomly divided into six groups. Mesial and distal dentinal surfaces of specimens were exposed by grinding and treated respectively with GC-DENTIN CONDITIONER. 10-3 solution of 4-Meta, Cleansar and Primer of GLUMA, Scotchprep of Scotchbond 2, DENTIN CONDITIONER and PRIMER A, B of ALL BOND according to the manufacturers directions. Specimens of one group were not treated. Adhesive agent of Scotchbond 2, were applied and cured on the treated dentin surfaces. After P-50 were cured on them, specimens were stored in 31c water for 24 hours before shear bond strength measurement Shear bond strength was measured in 10 specimens of each group. 10 specimens of each group were thermocycled in $20^{\circ}C$, $60^{\circ}C$,$20^{\circ}C$, $4^{\circ}C$, $20^{\circ}C$ water in order, for 30 seconds respectively, 100 times a day for 7 days. After thermocycling shear bond strength was measured. Microhardness was checked on treated dentin surface and fractured dentin surface in 10 specimens respectievly. Francture modes were observed with SEM The following results were obtained. 1. Before thermocycling. shear bond strengths in the specimens treated with DENTIN CONDITIONER and PRIMER A, B of ALL BOND were significantly higher than those in other specimens(P<0.01). 2. After thermocycling. shear bond strengths in the specimens treated with Cleanser and Primer of GLUMA, Scotchprep of Scotchbond 2 and DENTIN CONDITIONER and PRIMER A, B of AIL BOND were significantly higher than those in specimens not: treated, treated with GC-DENTIN CONDITIONER and 10-3 solution of 4-Meta(P<0.01). Shear bond strengths in the specimens treated with GC-DENTIN CONDITIONER and PRIMER A, B of ALL BOND were significantly higher than those in other specimens except those treated with Scotchprep of Srotchbond 2(P<0.01). 3. Shear bond strengths after thermocycling were reduced in the specimens not treated, treated with GC-DENTIN CONDITIONER and 10-3 solution of 4-Meta and were increased in the specimens treated with Cleanser and Primer of GLUMA, Scotchprep of Scotchbond 2, without significance, compared with those before thermocycling. In the specimens treated with DENTIN CONDITIONER and PRIMER A, B of ALL BOND, shear bond strengths after thermocycling were significantly increased, compared with those before thermocycling(P<0.01). 4. Microhardnesses in the fractured surfaces after shear bond strength measurement were significantly increased in the specimens treated with 10-3 solution of 4-Meta and significantly decreased in the specimens treated with DENTIN CONDITIONER and PRIMER A, B of ALL BOND, compared with those in the treated dentin surfaces(P<0.01). 5. In the specimens treated with Cleanser and Primer of GLUMA, Scotchprep of Scotchbond 2 and DENTIN CONDITIONER and PRIMER A, B of ALL BOND, cohesive fracture modes were observed more than adhesive fracture modes.

• Journal of Preventive Medicine and Public Health
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• 제7권2호
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• pp.313-318
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• 1974

An observation on bacteriological conversion upon 56 bocteriological positives out of 131 cases of lepromatous leprosy treated by antileprosy morbile service was carried out. Those 131 lepromatous cases were a part of 335 total registered from three Guns of Gangjin, Hwa sun, and Goheung, Cheollanamdo, since 1957 to 1973 that has been under the control of antileprosy morbile unit. The results obtained are summalized as follows, 1. Lepromatous type was 36.9% of all cases. The ratio of male to female was 4.9 to 1. Age between 30-44, the most productive ages, occupied 38.0% and age over 60 occupied 18.0% of all. 2. 42.7% of lepromatous type was bacteriological positive. 43.1% was for male and 43.1% was for female. Age between 20 to 24 shown the highest positive at 63.7% and followed by aged over 60 (62.5%) and under 19 (60.0%). The lowest one was seen at age between 40 to 44 at 29.2%. 3. Bacteriological positive rate at registration was different in accordance with duration of treatment received befor registration. It came up to the highest 100.0% at the group treated one year before registration. That of the group not received any treatment was 56.4%, and the group received 4-5 years was the lowest at 26.1% 4. Bacteriological conversion rate was 44.6% and 14.3% of all positive casese regressed in bacterial number. 37.5% of all active cases converted bacteriologically within 5 years. 5. Bacteriological conversion rate in group received 1 year treatment before registattion was 66.6%. That in group not received any treatment was 31.8% and group received 4-5 years was 33.3%. 6. Considering of total duration reaseved treatment together with before and after registration, 33.9% of all active cases resulted bacteriological conversion or regression within 5 years.