• Title/Summary/Keyword: All-on-4

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'All-on-4' fixed implant supported prosthesis restoration using digital workflow: a case report (Digital workflow를 활용한 'All-on-4' 임플란트 지지 고정성 보철물 수복 증례)

  • Sungwoo Ju;Seoung-Jin Hong;Janghyun Paek;Kwantae Noh;Ahran Pae;Kung-Rock Kwon;Hyeong-Seob Kim
    • The Journal of Korean Academy of Prosthodontics
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    • v.61 no.4
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    • pp.316-327
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    • 2023
  • In the case of fully edentulous patients with severe alveolar bone resorption, the consideration of 'All-on-X' implant-supported fixed prosthesis after placing four or more implants in the anterior maxilla is possible. Recent advancements in digital dentistry have enabled systematic and predictable treatment in all phases, including diagnosis, surgery, and prosthesis fabrication. By incorporating digital dentistry techniques such as digital complete denture, implant surgical guides, facial scanning into the conventional restoration process, it is possible to reduce the complexity of the prosthesis fabrication and effectively achieve the transition from provisional prosthesis to definitive prosthesis in terms of both aesthetics and function.

Hemopoietic and Radioprotective Effects of Several Herbs on Murine Splenocytes and Bone Marrow Cells (수(數) 종(種) 한약재(韓藥材)가 생쥐의 골수(骨髓) 및 비장세포(脾臟細胞)의 조혈촉진(造血促進)과 방사선(放射線) 방어(防禦)에 미치는 영향)

  • Lee, Neung-Gi;Choe, Seung-Hun;An, Gyu-Seok
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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    • v.3 no.1
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    • pp.29-48
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    • 1997
  • Astragalus membranaceus Bunge (黃?), Atractylodes macrocephala Loidz (白朮), Angelica sinensis(Oliv) Kiels (當歸), Lycium chinense Mill (枸杞子), Ligustrum lucidum Ail (女貞子) are Herbs that are frequently used in a lot of prescriptions to reduce the side effects of anti-cancer therapies, especially like chemotherapy and radiotherapy. The radioprotective and hemopoietic effects of these Herbs on BALB/c splenocytes and bone marrow cells are measured. In order to evaluate the Hemopoietic effects, Thymidine uptakes and secretion of colony stimulating factors(CSFs) of splenocytes and myelocytes treated with herbs were measured. Radioprotective effects were accessed by the method of immunocompetence of murine lymphocytes cultured with herbs before irradiation and with LPS, ConA after irradiation. The results are as follows. 1. The orders of Proliferative effects of herbs on splenocytes were Atractylodes macrocephala Loidz (白朮), the higest of all, Astragalus membranaceus Bunge (黃?), Angelica sinensis(Oliv) Kiels (當歸). Lycium chinense Mill (枸杞子) and Ligustrum lucidum Ait (女貞子), the lowest of all. At Optimal concentration, the proliferation ratios of herb-treated splenocytes compared to non-treated ones were like these. Atractylodes macrocephala Loidz (白朮) 44.3, Astragalus membranaceus Bunge (黃?) 17.7, Angelica sinensis(Oliv) Kiels (當歸) 10, Lycium chinense Mill (枸杞子) 6.4, Ligustrum lucidum Ait (女貞子) 2.0.(p<0.05) 2. When splenocytes were cultured during different periods, Atractylodes. macrocephala Loidz (白朮) and Astragalus membranaceus Bunge (黃?) showed the higest proliferation on 3th day, Angelica sinensis(Oliv) Kiels (當歸), Lycium chinense Mill (枸杞子) on 4th day,(p<0.05) and Ligustrum lucidum Ait (女貞子) until 5th day but with no significant increase. 3. The orders of Proliferative effects of herbs on Bone Marrow(BM) cells were Atractylodes macrocephala Loidz (白朮), the higest of all, Astragalus memhranaceus Bunge (黃?), Angelica sinensis(Oliv) Kiels (當歸), Lycium chinense Mill (枸杞子) and Ligustrum lucidum Ait (女貞子), the lowest of all too. At Optimal concentration, the proliferation ratios of herb-treated BM cells compared to non-treated ones were like these. Atractylodes macrocephala Loidz (白朮) 21.7, Astragalus membranaceus Bunge (黃?) 9.9, Angelica sinensis(Oliv) Kiels (當歸) 4.9, Lycium chinense Mill (枸杞子) 2.3, Ligustrum lucidum Ait (女貞子) 1.4(p<0.05). 4. The secretion ratio of colony stimulating factors(CSFs) of each herb-treated group, compared to control, was Atractylodes macrocephala Loidz (白朮) 9.4, Astragalus membranaceus Bunge (黃?) 9.0, Angelica sinensis(Oliv) Kiels (當歸) 4.4, Lycium chinense Mill (枸杞子) 3.8 (p<0.05) but no significant increase in Ligustrum lucidum Ait (女貞子). 5. The mitogen(ConA, LPS) stimulated-lymphocytes cultured with each herb before irradiation of 1-3 Gy showed more enhanced proliferation than control(p<0.05). When compared to each non-irradiated group of all groups, the orders of percentage increase of irradiated group were Atractylodes macrocephala Loidz (白朮), the higest of all, Astragalus membranaceus Bunge (黃?), Angelica sinensis(Oliv) Kiels (當歸), Ligustrum lucidum Ait (女貞子), Lycium chinense Mill (枸杞子). Each percentage showed significant enhancement compared to control group(p<0.05). According to the results, Atractylcdes macrocephala Loidz (白朮), Astragalus membranaceus Bunge (黃?) are suggested to be the most effective hemopoietic and radioprotective herbs, and Angelica sinensis(Oliv) Kiels (當歸), Lycium chinense Mill (枸杞子) the next, but Ligustrum lucidum Ait (女貞子) showed lower effects than expected.

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Potential on Hypotriglyceridemic Effect of Chloroform-Methanol Extract of Adlay Diabetic Rats

  • Cho, Youn-Ok;Lee, Mie-Soon
    • Journal of Nutrition and Health
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    • v.31 no.5
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    • pp.921-926
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    • 1998
  • The purpose of this study was to investigate the potential hypolipidemic effect of adlay extract in streptozotocin-induced diabetic rats. Fifty six rats were fed either a control diet or adlay extract diets of : Methanol 1%(Ml%) ; Methanol 2%(M2%) ; Methanol 4%(M4%) ; Chloroform-Methanol 1%(CMl%) ; Chloroform-Methanol 2%(CM2%) ; Chloroform-Methanol 4%(CM4%) for 3 weeks. The amount of extracts added was 1%, 2% or 4% by diet weight respectively. The levels of glucose, total cholesterol(TC), high-density-lipoprotein cholesterol (HDL-C), free-fatty acid(FFA) and triglyceride(TG) in plasma, liver and skeletal muscle were compared. Among diabetic rats, there were no significant differences in the plasma level of glucose and TC regardless of a different extraction procedure or different amount of extracts added. While the plasma 7G level tended to increase with times passed in diabetic control group, was not increased with times passed in CM groups and was significantly lower in CM groups at 3rd week. Compared to the diabetic control group, the levels of FFA tended to be lower in all M groups and were not different in all CM groups. The levels of HDL-cholesterol were not different in all M groups and were significantly lower in all CM groups than diabetic control group. Compared to diabetic control group, liver triglyceride level was lower in M4% group and no significant difference was seen in Ml%, M2% and all CM groups. Muscle triglyceride level tended to be lower in Ml%, M2% and CM2% group and significantly was lower in M4% and CM4% group. Thus, it can be suggested that a CM extract of adllay could have a potential hypotriglyceridemic effect on diabetic subjects. (Korean J Nutrition 31(5) : 921∼926, 1998)

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Balance Performance of 4-7 Year Olds (4세에서 7세까지 아동의 균형 수행력 비고)

  • Bae Sung-Soo;Lee han-suk
    • The Journal of Korean Physical Therapy
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    • v.11 no.2
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    • pp.21-28
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    • 1999
  • The purpose of this study were to describe the performance 67 kindergartener who aged from 4 to 7 years on the Pediatric Clinical Test of Sensory Interaction for Balance(P-CTSIB) and to determine difference with foot position and age. All Subjects were performance with different foot position that were feet-together, heel-toes. the starting position was that subject placed their hands on the hips, The results of this study were as follows 1. There were significiant difference in all instances by age whoa subjects were foot together(p<0.05). 2. There were singificiant difference in all instances by age excepts condition V awhen subjects were heel toes(p<0.05). 3. Duration of balance performance, of 4-year-olds were shortest and duration of balance performance of 7-year-olds were longest.

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A Study on Preventive Effect of Ginseng on All Cause Mortality -Kangwha Cohort Study- (인삼의 사망에 대한 예방효과에 관한 연구)

  • Yi, Sang-Wook;Hong, Jae-Suk;Ohrr, Hee-Choul
    • Journal of Ginseng Research
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    • v.27 no.4
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    • pp.158-164
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    • 2003
  • Recently, there are much concerns about ginseng as disease therapeutics. There are no epidemiologic study on relationship between ginseng intake and all cause mortality based from general population Cohort. This study sought to examine relationships between ginseng intake and all cause mortality from Kangwha Cohort data. From March 1985 through December 1999, 2696 males and 3595 females who were aged 55 or over as of 1985 were followed up. We calculate the mortality rate, standardized mortality ratio and risk ratios by ginseng intake. Cox proportional hazard model was used to adjust various confounding factors. Ginseng intake group had the lower all cause mortality(Risk ratio(RR)=0.88, 95%Confidence Interval(CI)=0.79-0.97) among males. Increasing ginseng intake, lower all cause mortality(Low ginseng intake: RR=0.88, 95%CI=0.79-0.98; high ginseng intake : RR=0.87, 95%CI=0.75-1.00) among males. There is no statistically significant difference between ginseng intake and mortality among females. The results of this study suggests that ginseng intake may prolong the human life among males.

COMPARISON OF TOPOLOGIES ON THE FAMILY OF ALL TOPOLOGIES ON X

  • Kim, Jae-Ryong
    • Journal of the Chungcheong Mathematical Society
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    • v.31 no.4
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    • pp.387-396
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    • 2018
  • Topology may described a pattern of existence of elements of a given set X. The family ${\tau}(X)$ of all topologies given on a set X form a complete lattice. We will give some topologies on this lattice ${\tau}(X)$ using a fixed topology on X and we will regard ${\tau}(X)$ a topological space. Our purpose of this study is to comparison new topologies on the family ${\tau}(X)$ of all topologies induced old one.

The use of precontoured plates for midshaft clavicle fractures is not always the best course of treatment

  • Manmohan Patel;Mohtashim Ahmad;Natwar Agrawal;Sumit Tulshidas Patil;John Ashutosh Santoshi;Bertha Rathinam;Kusum Rajendra Gandhi
    • Anatomy and Cell Biology
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    • v.56 no.4
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    • pp.456-462
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    • 2023
  • Plate fixation has become the preferred approach for treating displaced midshaft clavicle fractures. However, plate fixation of the clavicle presents several unique challenges, including its complex bony architecture and its immediate subcutaneous location. In many cases, we have observed that precontoured implants do not conform to the clavicular anatomy, and many patients complain of postoperative implant-related discomfort. A total of 111 clavicles, both left and right sides, were examined to match two commonly used designs of anatomical pre-contoured superior anterior clavicle plates, with and without lateral extension. The anteroposterior (AP) plane congruence of the plate to the underlying bone, the vertical gap between the bone and plate, and the length of the plate that was off the bone either anteriorly and/or posteriorly at both ends of the clavicle were measured. The scoring system was used to determine the fit of the implant on the clavicle as anatomic, good, or poor. We found that the maximum superior bow of the clavicle was lateral to the midline by 30.75 mm and 30.5 mm on the right and left sides, respectively. The magnitude of the bow was 4.28 mm and 4.46 mm on the right and left sides, respectively. We also found that the plate was a poor fit in 75.86% of cases on the left side and 73.5% of cases on the right side. Manipulating the plates during surgery was very difficult in the AP plane.

An Filtering Automatic Technique of LiDAR Data by Multiple Linear Regression Analysis (다중선형 회귀분석에 의한 LiDAR 자료의 필터링 자동화 기법)

  • Choi, Seung-Pil;Cho, Ji-Hyun;Kim, Jun-Seong
    • Journal of Korean Society for Geospatial Information Science
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    • v.19 no.4
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    • pp.109-118
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    • 2011
  • In this research estimated accuracies that were results in all the area of filtering of the plane equation that was used by whole data set, and regional of filtering that was driven by the plane equation for each vertual Grid. All of this estimates were based by all the area of filtering that deduced the plane equation by multiple linear regression analysis that was used by ground data set. Therefore, accuracy of all the area of filtering that used whole data set has been dropped about 2~3% when average of accuracy of all the area of filtering was based on ground data set while accuracy of Regional of filtering dropped 2~4% when based on virtual Grid. Moreover, as virtual Grid which was set 3~4 cm was difference about 2% of accuracy from standard data. Thus, it leads conclusion of set 3~4 times bigger size in virtual Grid filtering over LiDAR scan gap will be more appropriated. Hence, the result of this research allow us to conclude that there was difference in average accuracy has been noticed when we applied each different approaches, I strongly suggest that it need to research more about real topography for further filtering accuracy.

Effects of Several Inhibitors of Human Liver Microsomal Cytochrome P450 3A4 on Catalytic Activities of the Enzyme (인체 간 조직의 cytochrome P450 3A4의 활성에 대한 몇가지 억제제의 영향)

  • 오현숙;이갑상;김복량
    • Toxicological Research
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    • v.11 no.1
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    • pp.23-29
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    • 1995
  • Microsomes from human liver sample HL 110 oxidized aflatoxin $B_1$ $(AFB_1)$ to $AFB_1$ exo-8, 9-epoxide which was detected as a glutathione (GSH) conjugate with excess GSH S-transferase and to aflatoxin $Q_1$ ($AFB_1$; 3$\alpha$-hydroxyafiatoxin $B_1$), and testosterone to 6$\beta$-hydroxytestosterone. Anti-P450 3A4 nearly completely inhibited all of the reactions. Some fiavonoids inhibited all of the reactions. While other fiayonolds stimulated 8, 9-epoxidation and inhibited 3$\alpha$-hydroxylation. Gestodene inhibited all of the reactions when gestodene was metabolized by human liver microsomal P450 3A4 prior to adding substrate. But, ges-todene was added in the enzyme mixtures in the presence of $AFB_1$, it could not inhibit 8, 9-epoxidation of $AFB_1$. Nifedipine and troleandomycin inhibited both of the reactions of $AFB_1$ but only 3$\alpha$-hydroxylation was inhibited by the oxidation product of nifedipine. Although, troleandomycin was known as a mechanism-based inhibitor, the chemical did not show any detectable inhibitory effect on 6$\beta$-hydroxylation of testosterone. The results suggest that there are several different substrate-binding sites on P450 3A4.

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An Analysis of Air Pollution Effect in Urban Area Related to Asian Dust on All-cause and Cause-specific Mortality in Seoul, Korea, 2000-2006 (도시 대기오염의 위해 평가에 있어서 황사효과 분석 -서울시 총사망 및 원인별 사망률에 미치는 영향-)

  • Son, Ji-Young;Cho, Yong-Sung;Kim, Yoon-Shin;Lee, Jong-Tae;Kim, Yeon-Jung
    • Journal of Environmental Health Sciences
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    • v.35 no.4
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    • pp.249-258
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    • 2009
  • The objectives of this study were to compare the relative risk of all-cause mortality and cause-specific mortality associated with Asian dust events, and especially to investigate the effects on the susceptible population such as the elderly and children, which were based on the data in Seoul from 2000 to 2006. Both of the study periods with/without Asian dust days, respiratory-cause mortality was the highest, followed by cardiovascular-cause mortality and all-cause mortality in sequence among mortality related to air pollution for all-aged group. As to susceptible group, the relative risk of mortality is the highest for +65 yrs group among all-cause mortality. According to comparison of mortality with/without Asian dust days, the relative risk of all-cause mortality is larger in the model with Asian dust days than the one in the model without Asian dust days among all age group (except for under 15 yrs group) and all air pollutants. The relative risk of cause-specific mortality (except for ozone in under 15 yrs group in case of respiratory-cause mortality, and ozone in all age group and over 65 yrs group in case of cardiovascular-cause mortality) per IQR increase of each pollutant is larger in the model without Asian dust days.