• Journal of Preventive Medicine and Public Health
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• 제39권3호
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• pp.221-228
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• 2006

Objectives: The purpose of this study was to shed further light on the effect of modifiable health behavior risk factors on dependence in activities of daily living, defined in a multidimensional fashion. Methods: The study participants were 10,278 middle aged Americans in a longitudinal health study, the Health and Retirement Survey (HRS). A multi-stage probability sampling design incorporating the effect of population sizes (Metropolitan and non-metropolitan), ethnicity (the non- Hispanic White, the Hispanic, and the Black), and age (age 51-61) was utilized. Basic Activities of Daily Living (ADL) were measured using five activities necessary for survival (impairment in dressing, eating, bathing, sleeping, and moving across indoor spaces). Explanatory variables were four health behavior risk factors included smoking, exercise, Body Mass Index (BMI), and alcohol consumption. Results: Most participants at baseline were ADL independent (1992). 97.8% of participants were independent in all ADL's at baseline and 78.2% were married. Approximately 27.5% were current smokers at baseline, and the subjects reported moderate or heavy exercise were 74.8%. All demographic characteristics and behavioral risk factors were significantly associated with the ADL status at Wave 4 except alcohol consumption. Risk behaviors such as current smoking, sedentary life style and high BMI at Wave 1 were associated with ADL status deterioration; however, moderate alcohol consumption tended to be more related to better ADL status than abstaining at Wave 4. ADL status at Wave 1 was the strongest factor and the next was exercise and smoking affecting ADL status at Wave 4. People who were in ADL dependent at Wave 1 were 15.17 times more likely to be ADL dependent at Wave 4 than people who were in ADL independent at Wave 1. Concerning smoking cigarettes, people who kept only light exercise or sedentary life style at Wave 1 were 1.70 times more likely to be died at Wave 4 than the people who did not smoke at Wave 1. Conclusions: All demographics and health behaviors at wave 1 had consistently similar OR trends for ADL status to each other except alcohol consumption. Smoking and exercise in health behaviors, and age and gender in demographics at Wave 1 were significant factors associated with ADL group separation at Wave 4.

• 생물정신의학
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• 제13권3호
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• pp.178-190
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• 2006

목 적: 유전적 요인에 다른 금단 증상의 차이를 파악하는 것은 알코올 의존의 유전적 요인을 파악하는데 도움이 될 수 있으며, 유전적 요인에 따라 개인별 금단 증상을 예측할 수 있다. 본 연구의 목적은 유전자군의 다형성에 따른 금단 증상의 심각도 및 증상의 종류를 파악하는 것이며 이에 따른 치료적 접근을 다양하게 하는 것이다. 방 법: 대상군으로는 19세 이상 65세 이하의 남자 입원 환자 108명을 대상으로 하였고, 유전자 분포 비교를 위하여 76명의 대조군을 두었다. 금단 증상의 평가는 마지막 알코올 섭취로부터 48시간이 지난 시점에서 Clinical Institute Withdrawal Assessment for Alcohol(이하 CIWA-Ar) 척도를 사용하여 평가하였다. 도파민 수송체, 도파민 수용체(DRD2), Catechol-O-Methyltransferase(COMT) 유전자형을 분석하였다. 결 과: 나이, 교육 기간, 유전자 형에서 알코올 의존 군과 대조군 사이의 유의한 차이는 없었다. DRD2 Taq I : 동형 유전자형에서 환청 항목의 점수가, 이형 유전자형에서 CIWA-Ar 총점의 점수가 높았다. 환청 항목의 비교 위험도가 1.34이었다. DAT1 : DAT-9 대립유전자를 가지지 않은 유전자형 집단에서 발한, 불안, CIWA-Ar 총점 항목에서 높은 점수를 보였다. COMT : 유전자 빈도를 보면 이형 유전자형이 동형 유전자형에 비해 CIWA-Ar 총점의 점수가 높았다. 결 론: DRD2, DAT1, COMT 유전자 다형성은 다양한 알코올 금단 증상과 관련이 있으며, 이는 각 유전자와 관련된 신경전달 물질과 연관되어 작용하는 것으로 생각된다. 또한 금단 증상의 심각도와도 밀접한 관련이 있는 것으로 생각되어 알코올 금단 증상을 보이는 환자의 치료에 중요한 역할을 할 것으로 생각된다.

• 폴리머
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• 제36권5호
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• pp.628-636
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• 2012

폴리(비닐 알코올)(PVA)/디메틸설폭사이드 용액에 폴리스티렌 라텍스 구형입자(직경 범위: 100~300 nm)를 소량 첨가한 뒤, 구형 입자 표면에 형성된 사슬 배제층 두께가 사슬의 농도에 따라 어떻게 의존하는지를 동적 광산란법으로 조사하였다. 묽은 용액 농도에서는 배제층의 두께가 PVA 사슬의 회전반경의 $63{\pm}3%$ 수준에서 일정하게 유지되었었으나 준희박 용액 농도의 초기 영역인 $1.5{\leq}C[{\eta}]{\leq}3$ 범위에서는 배제층 두께 ${\delta}$의 고분자 농도 의존성은 이론치 -0.75와 비슷한 ${\delta}{\sim}C^{-0.8}$로 얻어졌다. 보다 높은 농도 $C[{\eta}]$ >3 이상에서는 배제층의 두께가 급격히 감소하는 것으로 나타났는데 그 이유는 탐침입자간 Oosawa 인력에 의하여 유발된 응집효과가 그 원인인 것으로 설명할 수 있었다.

• 정신신체의학
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• 제5권1호
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• pp.31-42
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• 1997

This study was aimed to investigate dysfunctional attitudes, stress coping strategies and depressive symptoms in psychiatric patients. The subjects of this study consisted of 210 patients(138 schizophrenic patients, 29 depression patients, 43 alcohol dependence patients) according to DSM-IV criteria. Futhermore, the instruments were K-BDI(Beck Depression Inventory-Korean version), DAS(Dysfunctional Attitude Scale) and multidimensional coping strategy scale. The results were the following. 1) There were statistically significant correlations between depressive symptoms and dysfunctional attitudes in psychiatric patients. 2) In terms of coping strategies, there were positive correlations between depressive symptoms and focus on and venting emotions, accommodation, active forgetting, self-criticism, positive comparison, fatalism, passive withdrawal. Whereas, there was significant negative correlation between depressive symptom and active coping. 3) In terms of coping strategies, there were significant correlations between dysfunctional attitudes and focus on and venting emotions, active forgetting, self-criticism, positive comparison, fatalism, passive withdrawal. 4) Depression groups reported significantly higher BDI scores than schizophrenia groups. 5) In depression groups, DAS scores were significantly higher than those in schizophrenia groups. 6) In terms of coping strategies according to diagnosis, there were significant differences in venting emotions, active forgetting and self-criticism. As for venting emotions, alcoholic groups were scored significantly higher than schizophrenic groups. As for active forgetting, depression groups were scored significantly higher than schizophrenic groups. In self-criticism, depression groups and alcohol dependence groups reported significantly higher scores than schizophrenic groups.

• 대한불안의학회지
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• 제7권2호
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• pp.73-78
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• 2011

본 연구 결과 여성에서의 문제음주와 알코올 의존 비율이 남성보다는 적지만 9.8%로 상당수의 여성들이 알코올 문제를 겪고 있음을 알 수 있었다. 그리고 직장 생활을 하는 여성에서 음주 노출 기회가 더 많고, 실제로 음주에 대한 문제가 더 많이 발생하며 이는 여성의 상태불안과 충동성과 관계가 있다. 여성에서는 직업을 가짐으로써 음주 노출기회가 많아지고 직장 생활에서의 불안 및 충동성이 문제 음주를 일으키는 원인이 될 수 있음을 예상해 볼 수 있겠다. 따라서 직장 여성의 음주 노출 기회와 불안 및 충동성 조절이 음주 위험 요소의 중요한 조절 요인으로 생각된다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제25권4호
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• pp.209-216
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• 2014

Objectives : Alcohol use disorder (AUD) is often comorbid with adult attention-deficit hyperactivity disorder (ADHD) and other psychiatric illnesses. When associated with other mental problems, the prognosis of the AUD can be more serious. This study shows research on the clinical and neuropsychological characteristics according to whether or not ADHD symptoms and AUD were comorbid. Methods : A total of 64 adult inpatients who completed AUD scales about adult ADHD, alcohol dependence, depression, anxiety, and impulsiveness. They also completed neuropsychological tests about attention and executive function. According to the Adult ADHD Self-Report Scale score, patients were categorized into two groups (ADHD symptom positive/negative group). Results : Fourteen among the 64 subjects were part of the ADHD symptom positive group (21.9%). They had statistically significant shorter abstinence periods and a higher rate of history of 'rule violation during school' and 'physical damage in childhood' compared to the ADHD symptom negative group. Conclusion : The comorbidity rate with ADHD symptom in adult AUD is higher than the general population. The ADHD symptom positive group suffered from more severe and refractory AUD. Considering the more frequent history of rule violation during school in the ADHD symptom positive group, the association between ADHD and AUD may be mediated by conduct disorder. Therefore we suggest the necessity of careful evaluation and intervention in children and adolescents with ADHD and conduct disorder.

• 융합정보논문지
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• 제9권5호
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• pp.235-242
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• 2019

본 연구에서는 '알코올 의존 노숙인을 위한 사회복지적 지원의 핵심은 가족을 대체할 만한 영향력 있는 관계'일 수 있다는 문제의식을 바탕으로, 중림동 쪽방촌 일대에서 알코올 의존 노숙인을 지원하는 'H-공동체'의 사례를 스프레들리가 제시한 문화기술지 방식으로 탐색하였다. 연구결과 알코올 의존자들은 H-공동체를 중심으로 '가족을 대체할만한 관계'를 맺고 있었으며, 그 속에서 '정서적 유대감'을 형성하고 있었다. 그리고, 이는 '큰 정은 없어도 잔정으로 살아가기'라는 문화적 주제로 나타났다. 하지만, 그 관계와 유대감 정도는 다르게 나타났으며, 이는 각자의 생애과정과 건강, 나이, 경제 상황과 무관하지 않았다. 논의에서는 이 같은 차이를 '가족을 대체할만한 관계', '정서적 유대감', '참여' 정도를 통해 유형화시키고 논점으로 제안하였다. 결론에서는 연구결과를 바탕으로 알코올 의존 노숙인에게 필요한 함의를 제시하고 제언을 하였다.

• 지역사회간호학회지
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• 제15권3호
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• pp.471-482
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• 2004

Purpose: This study intended to identify personality factors and related problematic behaviors of adolescents who drink alcohol in order to provide basic data for developing nursing programs. Methods: The data were collected from October to December 2002 from 1.080 high school students in Seoul. The Revised Cloninger's Tri-dimensional Personality Questionnaire (TPQ) was used to measure their personalities. The alcohol expectancy was measured using the tool revised by Cho (1999) and stress levels were measure using a stress tool revised Cho (1998). The data were analyzed with SPSS Windows using Chi square test. independent t-test. and logistic regression analysis. Results: 1. The percentage of fathers who drank was 79.8%. mothers. 54.3%. and friends. 54.3%. The alcohol expectancy averaged 6.36 while the stress levels were 132.79. 2. It was found that there are significant differences (p<.001) in problematic drinking behaviors according to the following variables: second year high school students among all grade variables, more monthly pocket money for the amount of money variables, the group of students who smoked in the case of the variable related to smoking, spending more time using the Internet for the Internet use variable, and having friends who drink 65.6% for the friend variable. The alcohol expectancy scale of those students who showed problematic drinking behaviors was higher than that of those who did not. There are four family-related stress subscales, and there was a significant difference among them (p<.05). Among the personal characteristics, the group who displayed problematic drinking behaviors seeks new experiences and reward dependence more than the group who did not exhibit those behaviors, and there were significant differences between the two groups (p<.001). 3. When the socio-demographic and drinking-related factors were controlled, the tendency of seeking new experiences increased the risk of problematic behaviors 1.07 times (p<.05). Compared to the non smoking group, the smoking group was found to have a 5.06 time (p<.001) greater risk of displaying problematic drinking behaviors. In comparison with the non drinking group, the drinking group was also found to have a 5.31 time (p<.001) greater risk of exhibiting problematic drinking behaviors. The group with high alcohol expectancy scores was significantly different from the group with the no alcohol expectancy, showing a 1.26 time (p<.00l) greater risk of problematic drinking behaviors. Conclusions: Based on these results, the problematic drinking behaviors were connected with alcohol expectancies, friends and personality types. Therefore, we should develop an alcoholic prevention program for adolescence considering the above results.

• 한국HCI학회:학술대회논문집
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• 한국HCI학회 2008년도 학술대회 1부
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• pp.823-828
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• 2008

본 연구는 음주거절훈련을 위한 전 단계로 가상현실을 통한 자극 제시가 알코올 중독 환자의 갈망감에 어떠한 변화를 주는 지를 알아보고자 하였다. 본 연구결과를 통해 향후 음주 거절 훈련 프로그램의 개발 뿐만 아니라 알코올 중독 환자들을 위한 새로운 치료 및 훈련 도구로서의 가상현실기법의 활용 가능성을 알아보기 위한 기초적인 자료 제공을 목적으로 한다. 가상현실 자극은 알코올 중독자들의 음주유발 상황으로 알려진 음주권유(사회적 압력)상황과 알코올 노출 여부 그리고 긍정적 상황 부정적 상황으로 구성하였다. 대상자는 2006년 12월부터 2007년 9월까지 입원중인 알코올 중독 환자 12명이었으며 수집된 자료는 SPSS/WlN 11.5 프로그램으로 통계처리 하였으며, Wilcoxon Matched-pairs Signed-Ranks Test로 분석하였다. 분석 결과 배경에서 아바타의 음주권유 여부가 일반적인 배경만 제시되는 경우보다 더 높은 갈망감을, 알코올이 노출된 장면이 그렇지 않은 장면보다 더 높은 갈망감을 나타내었고 긍정적 부정적이냐는 상황은 유의미한 결과를 나타내지 못하였다. 이러한 결과를 토대로 가장현실을 활용한 훈련이 실제의 사회적 압력과 유사한 음주 압력 상형과 환경을 느끼도록 하며, 가상현실 기법이 기존의 알코올 치료 기법들과 연합되어 효과적인 치료 도구로써의 활용가능성을 많이 가지고 있다는 것을 확인 할 수 있었다.

• 한국감성과학회:학술대회논문집
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• 한국감성과학회 2009년도 춘계학술대회
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• pp.101-104
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• 2009

This study investigated compensatory mechanisms in the brain during a verbal working memory task among people with Alcohol Use Disorders (AUD). A total of 21 college male students participated in the study: eleven AUD participants and 10 normal controls. Study participants were asked to complete the Korean version of the Wechsler Adult Intelligence Scale-III (K-WAIS-III) prior to the fMRI experiment. Verbal 0-back and 2-back tasks were used to assess brain activities of the participants' verbal working memory. Brain scanning was performed on Siemens SONATA 1.5T Scanner while participants were performing the 0-back and 2-back tasks. Within the AUD group, participants with greater dependency to alcohol (based on DSM-IV criteria) in the past 1 year showed lower mean score on the 'Similarities' of the K-WAIS-III (r=-0.63, p<0.05, N=11). The more participants experienced alcohol withdrawal symptoms in the past 1 year, the lower the score they received on the K-WAIS-III 'Picture Arrangement' (r=-0.69, p<0.05, n=11). The fMRI regression results showed that individuals who present greater degree of alcohol dependency symptoms are likely to show greater brain activation in the bilateral middle frontal gyri (BA 9) during the verbal working memory task. The degree of alcohol withdrawal symptoms were associated with increased brain activation in the left superior and middle frontal gyri (BA8), left precentral gyrus (BA 6), and left inferior parietal lobule (BA 40). The study findings showed that the degree of alcohol abuse/dependence and withdrawal symptoms were associated with decreased cognitive function and increased activations in brain regions particularly important for abstract reasoning (BA 9), central executive (BA 9), or spatial storage (BA 40) during a working memory task. Therefore, these results could support previous studies suggesting that the neural system of people with ADD may adopt a brain compensatory mechanism to maintain normal level of cognitive functions.