• 제목/요약/키워드: Alcohol Use Disorders

검색결과 98건 처리시간 0.023초

Factors Affecting the Downward Mobility of Psychiatric Patients: A Korean Study of National Health Insurance Beneficiaries

  • Kim, Un-Na;Kim, Yeon-Yong;Lee, Jin-Seok
    • Journal of Preventive Medicine and Public Health
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    • 제49권1호
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    • pp.53-60
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    • 2016
  • Objectives: The purpose of this study is to examine the magnitude of and the factors associated with the downward mobility of first-episode psychiatric patients. Methods: This study used the claims data from the Korean Health Insurance Review and Assessment Service. The study population included 19 293 first-episode psychiatric inpatients diagnosed with alcohol use disorder (International Classification of Diseases, 10th revision [ICD-10] code F10), schizophrenia and related disorders (ICD-10 codes F20-F29), and mood disorders (ICD-10 codes F30-F33) in the first half of 2005. This study included only National Health Insurance beneficiaries in 2005. The dependent variable was the occurrence of downward mobility, which was defined as a health insurance status change from National Health Insurance to Medical Aid. Logistic regression analysis was used to assess factors associated with downward drift of first-episode psychiatric patients. Results: About 10% of the study population who were National Health Insurance beneficiaries in 2005 became Medical Aid recipients in 2007. The logistic regression analysis showed that age, gender, primary diagnosis, type of hospital at first admission, regular use of outpatient clinic, and long-term hospitalization are significant predictors in determining downward drift in newly diagnosed psychiatric patients. Conclusions: This research showed that the downward mobility of psychiatric patients is affected by long-term hospitalization and medical care utilization. The findings suggest that early intensive intervention might reduce long-term hospitalization and the downward mobility of psychiatric patients.

Comparison of Microbial Diversity and Composition in the Jejunum and Colon of Alcohol-Dependent Rats

  • Fan, Yang;Ya-E, Zhao;Ji-dong, Wei;Yu-fan, Lu;Ying, Zhang;Ya-lun, Sun;Meng-Yu, Ma;Rui-ling, Zhang
    • Journal of Microbiology and Biotechnology
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    • 제28권11호
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    • pp.1883-1895
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    • 2018
  • Alcohol dependence is a global public health problem, yet the mechanisms of alcohol dependence are incompletely understood. The traditional view has been that ethanol alters various neurotransmitters and their receptors in the brain and causes the addiction. However, an increasing amount of experimental evidence suggests that gut microbiota also influence brain functions via gut-to-brain interactions, and may therefore induce the development of alcohol use disorders. In this study, a rat model of alcohol dependence and withdrawal was employed, the gut microbiota composition was analyzed by high-throughput 16S rRNA gene sequencing, and the metagenome function was predicted by PICRUSt software. The results suggested that chronic alcohol consumption did not significantly alter the diversity and richness of gut microbiota in the jejunum and colon, but rather markedly changed the microbiota composition structure in the colon. The phyla Bacteroidetes and eight genera including Bacteroidales S24-7, Ruminococcaceae, Parabacteroides, Butyricimonas, et al were drastically increased, however the genus Lactobacillus and gauvreauii in the colon were significantly decreased in the alcohol dependence group compared with the withdrawal and control groups. The microbial functional prediction analysis revealed that the proportions of amino acid metabolism, polyketide sugar unit biosynthesis and peroxisome were significantly increased in the AD group. This study demonstrated that chronic alcohol consumption has a dramatic effect on the microbiota composition structure in the colon but few effects on the jejunum. Inducement of colonic microbiota dysbiosis due to alcohol abuse seems to be a factor of alcohol dependence, which suggests that modulating colonic microbiota composition might be a potentially new target for treating alcohol addiction.

북한어판 CES-D(Center for Epidemiologic Studies Depression Scale-North Korea ; CES-D-NK)의 신뢰도와 타당도 (Reliability and Validity of the North Korean Version of Center for Epidemiologic Studies Depression Scale (CES-D-NK))

  • 박승진;이소희;전진용;이태엽;한정미;안명희;홍진표
    • 대한불안의학회지
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    • 제11권1호
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    • pp.54-60
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    • 2015
  • Objective : To translate Center for Epidemiologic Studies Depression Scale (CES-D) into North Korean language and to examine its reliability and validity Methods : North Korean defectors (n=207) recruited from the call center for North Korean defectors participated. Psychiatrists and psychiatric residents interviewed the participants and made the psychiatric diagnoses. Subsequently, the participants completed the CES-D, Impact of Event-Scale-Revised-North Korea (IES-R-NK), Alcohol Use Disorders Identification Test-North Korea (AUDIT-NK), and Brief Psychological State Inventory for North Korean Refugees (BPSI-NKR) questionnaires. Of the original participants, 143 subjects participated in test-retest reliability study after one week. Results : Cronbach's alpha coefficient of CES-D-NK was superior in both males (0.91) and females (0.93). The test-retest correlation coefficient was high (males, 0.64 ; femals, 0.79). Good convergent validity was evident by significant correlations with IER-R-NK, BPSI-NKR-Depression and BPSI-NKR-PTSD, respectively. CES-D-NK had no or weak correlations with AUDIT-NK and BPSI-NKR-Alcohol, showing its discriminant validity. Conclusion : CES-D-NK could be a reliable and valid tool for screening and assessing depressive symptoms of North Korean defectors.

The Relationship Between the Severity of Drinking and Suicidal Ideation in The General Korean Population-Analysis by Gender and Age Groups

  • Lee, SunMin;Shin, Young-Chul;Shin, Dong-Won;Oh, Kang-Seob;Jeon, Sang-Won;Kim, Eun-Jin;Cho, Sung Joon
    • 대한불안의학회지
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    • 제16권2호
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    • pp.91-97
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    • 2020
  • Objective : The suicide mortality rate among Koreans was ranked first among the OECD countries in 2018. Alcohol consumption is a significant risk factor for suicidal behavior. This study examined the relationship between the severity of subjects' drinking habits and the suicidal ideation among Koreans according to gender and age. Methods : The data of 113,602 people who visited the Kangbuk Samsung Hospital Health Screening Center from January 2013 to December 2014 were used. The severity of subjects' harmful drinking habits was assessed using the Korean version of the Alcohol Use Disorders Identification Test (AUDIT-K). The relationship between the severity of harmful drinking and suicidal ideation was compared using logistic regression analyses. We also examined the tendency through p for trend to identify a trend. Results : Of the 113,602 study subjects, 6,586 (5.8%) responded that they had thought of committing suicide. After controlling for gender, marriage, education, body mass index (BMI), depression and anxiety, the results showed that the higher the level of harmful drinking, the higher the suicidal ideation. Conclusion : This study found that, even after controlling depression and anxiety, the severity of drinking could be a significant risk factor for suicidal ideation.

우울 및 불안장애 환자에서 성별 및 성경험 유형에 따른 부정적 성경험과 정신과적 증상 사이의 연관성 (Relationship between Negative Sexual Experience and Psychiatric Symptoms in Patients with Depression or Anxiety Disorders by Gender and Type of Negative Sexual Experience)

  • 지민아;정보람;채정호
    • 대한불안의학회지
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    • 제15권2호
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    • pp.77-83
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    • 2019
  • Objective : This study aims to investigate the relationship between negative sexual experience and psychiatric symptoms by gender and compare the effects of sexual assault and unwanted sexual experiences on psychiatric symptoms in patients with depression or anxiety disorders. Methods : A total of 204 respondents who have had negative sexual experiences of outpatients diagnosed with depression or anxiety disorders were evaluated with AUDIT, PSS, STAI, BDI, and SSI. Independent samples t-test was performed to compare the psychiatric symptom scale scores between male and female and identify the difference of the psychiatric symptom scale scores between those who have had sexual assault and those who have had only unwanted sexual experience. Results : There was no difference in psychiatric symptom scale scores except for AUDIT between male and female in 204 patients with negative sexual experience. There was also no significant difference in AUDIT, PSS, and STAI scores between those who experienced sexual assault and those who experienced only unwanted sexual experiences. BDI and SSI scores are significant higher in those who experienced sexual assault than those who experienced only unwanted sexual experiences. Conclusion : This suggests that male and female may have similar levels of psychiatric symptoms after experiencing negative sexual experiences. Psychiatric symptoms caused by sexual assault may have differences from the psychiatric symptoms caused by unwanted sexual experience. Understanding the differences in psychiatric symptoms according to the type of negative sexual experience may helpful to direct the therapeutic plans.

가상현실을 활용한 중독치료의 동향과 전망을 위한 체계적 문헌고찰 (Trend and Future of Virtual Reality for Addiction Treatment of Substance Use Disorders: A Systematic Review)

  • ;김진수;김나미
    • 디지털콘텐츠학회 논문지
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    • 제18권8호
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    • pp.1551-1560
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    • 2017
  • 본 논문의 목적은 가상현실을 활용한 중독치료의 동향 파악을 위해 중독의 종류와 물질사용장애에 대한 가상현실치료 방법을 분류하고 분석하는 것이다. 가상현실은 다양한 정신장애 및 심리문제를 치료하기 위한 새로운 패러다임으로 활용되어 왔다. 최근에는 많은 연구가 수행되어 중독치료, 특히 물질사용장애에 대한 가상현실치료의 효과를 입증하였다. 이러한 연구들의 경향을 파악하기 위하여, 이 논문은 학술문헌 데이터베이스인 ScienceDirect, MEDLINE, ProQuest 그리고 Embase에 등재된 논문들을 체계적으로 검토하였다. 그 결과 45편의 연구논문들이 검색되었는데, 이 연구들 중에서 니코틴/흡연에 관하여 가장 많은 연구 (73 %, n = 33)가 되었고, 알코올 (18 %, n = 8), 대마초/마리화나 (2 %, n = 1), 그리고 헤로인, 코카인, 메스암페타민 등 기타 약물(7 %, n = 3)에 대한 연구가 이루어졌다. 이 논문은 이러한 연구들의 결과를 분석하고, 장점뿐만 아니라 몇 가지 한계점을 발견했으며, 가상 현실기술을 이용한 중독치료에 대한 추가연구 방향을 제시하였다.

노숙인 시설 입소 대상자의 음주실태와 음주문제 관련요인: 인천광역시 노숙관련 시설을 중심으로 (Factors related to Drinking Problems among the Homeless in Homeless Facilities in Incheon)

  • 김희경;이미형;한진숙;이상희
    • 보건교육건강증진학회지
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    • 제31권2호
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    • pp.15-26
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    • 2014
  • Objectives: This study investigates the drinking state of the homeless, including the factors that influence this state, and the related services that the homeless require. Methods: A total of 163 adults residing in homeless shelters in Incheon, were recruited from November 15 to December 28, 2013. The Korean version of the Alcohol Use Disorders Identification Test was used. The data collected were analyzed using descriptive statistics, ANOVA, chi-square, and logistic regression. All analyses were conducted using SPSS 18. Results: Among the respondents, 59.5% engaged in normal drinking, 17.2% engaged in problem drinking and 23.3% suffered from high risk drinking. Alcohol Problems of homeless were found to increase along with total drinking periods. And high risk drinker were more likely to have 3.2 times of loneliness, 6.5 times of insomnia, and the reason for homeless is alcohol problem 14.0 times higher. Conclusions: Alcohol problems among the homeless are chronic and difficult to solve through temporary measures and short-term interventions. Therefore, the development of appropriate services and policies for the homeless is important. The results of the study can be used as a basis for the development of management measures tailored to the distinctive needs of the homeless.

안전한 대학생활을 위한 제주지역 대학생들의 음주행동연구 (Drinking behavior survey of university students in Jeju for the safe campus life)

  • 김효실;이영아;김수진;채수경;임진형
    • 한국응급구조학회지
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    • 제20권2호
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    • pp.127-144
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    • 2016
  • Purpose: The purpose of this study was to investigate the drinking behavior of university students in Jeju for the safe campus life. Methods: A self-reported questionnaire was completed by 549 students in 4 universities in Jeju. The data were analyzed by t-test, one way ANOVA, and multiple regression using SPSS Win 19.0 program. The questionnaire instruments consisted of Alcohol Use Disorders of Identification Test-Korea (AUDIT-K) and Life Stress Scale for College Students adapted by Chon. Results: The alcohol consumption rate of participants accounted for 96.2%. The binge drinking rate in female students were 33.9% and that in male students was 29.5%. The result by scoring AUDIT showed that 30.7% of participants were normal drinking group, 36.0% were hazardous drinking group, and 33.3% were estimated alcohol abuse group. The average score of stress was 1.45 by Likert 4 point scale. The female students tended to have more stresses than male. The most important influencing factors on drinking behavior were the first alcohol drinking(${\beta}=-.250$, p< .001), gender(${\beta}=.202$, p< .001), and relationship problem(${\beta}=.116$, p < .05). Conclusion: The drinking rate of university students revealed higher than that in other age groups. So the early systematic education is strongly recommended to prevent the physical and mental side effects.

우리나라 대학생의 음주행태 심층조사 (College Alcohol Study for Alcohol-Related Behaviors and Problems)

  • 주영준;오소연;박상익;이혜자;유민규;박은철
    • 보건행정학회지
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    • 제29권1호
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    • pp.58-67
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    • 2019
  • Background: In this study, we aimed to investigate the drinking behaviors and drinking-related problems of college students in South Korea to produce national alcohol statistics. Methods: We carefully examined the questionnaires and previous research developed in the previous research project and selected questions that reflect the special environment and culture of college students. In order to stratify a nationally representative sample of college students, the distribution of students around the country were found through the educational statistics database of the Korea Educational Development Institute. Based on this information, we conducted a survey in collaboration with Gallup (Korea) to survey and analyze the drinking behaviors of 5,024 Korean students. Results: A nationwide cross-sectional survey was conducted in 2017, for Korean college students. A total of 5,024 students were recruited and analyzed. The monthly drinking rate was 78.0% for male students and 72.9% for female students. The high-risk drinking rate was 23.3% for male students and 17.2% for female students. The most popular category for number of drinks per drinking session was 'more than 10 glasses' per drinking session for both male (44.1%) and female (32.8%). On the alcohol use disorders identification test, the greatest proportion of male students were in the high-risk drinking category (score 8 to 15) 43.8%, followed by the 'low-risk drinking' (score 0 to 7) in 43.6%, 'alcohol abuse' (score 16 to 19) 7.2%, and 'alcohol dependence' (greater than 20) 5.4% categories, respectively. For female students, the greatest proportion of female students were in the 'low-risk drinking' in 49.6%, followed by 'high-risk drinking' 37.1%, 'alcohol abuse' 8.4%, and 'alcohol dependence' 4.9% categories, respectively. Conclusion: The results of the study showed that the drinking behavior of Korean college students was excessive. Overall, it was found that the college population has a greater high-risk drinking behaviors than general adult population. Furthermore, these problem drinking behaviors were prominent among female college students. Results from the present study suggest that it is necessary to monitor the drinking behavior of college students with constant interest and to prepare policies and strategies suitable for these circumstances.

수면클리닉을 방문한 환자들의 불면증에 대한 인식조사 (Survey of Knowledge on Insomnia for Sleep Clinic Clients)

  • 소민아
    • 수면정신생리
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    • 제26권1호
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    • pp.23-32
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    • 2019
  • 목 적 : 본 연구의 목적은 수면장애로 수면클리닉에 내원하는 환자들을 대상으로 수면클리닉을 방문하게 된 이유, 찾게 된 경로, 수면클리닉을 찾게 되는 가장 흔한 증상이자 독립질환인 불면증에 대한 인식을 조사하고 그 의미를 해석하여 향후 수면장애의 치료와 환자교육에 도움이 되고자 하였다. 방 법 : 2018년 4월부터 10월 사이 6개월 간 국립정신건강센터의 수면클리닉을 방문한 외래환자들 중 만 19세 이상의 초진환자를 대상으로 자기보고식 설문을 진행하였다. 이때, 지적장애, 치매 등 심한 인지기능을 동반한 환자등을 배제하였고, 총 44명(남성 24명, 여성 20명)이 연구에 참석하였다. 설문지는 자체개발한 설문지로 수면클리닉을 방문한 이유, 수면클리닉을 알게 된 경로, 수면클리닉 방문 이전 수면질환의 치료력, 불면증의 인식에 대한 질문, 불면증의 치료에 대한 인식, 불면증의 동반질환(comorbodity)에 대한 지식을 묻는 질문으로 구성되었다. 결 과 : 연구에 참가한 대상자들은 총 44명으로 평균 연령은 $54.11{\pm}16.3$세로 남성은 24명(54.5%), 여성은 20명(45.5%)였으며, 40대 이상의 중장년층이 전체의 77.3%를 차지했고, 81.8%(36명)가 고졸이상의 학력을 갖추고 있었다. 환자들의 72.7%(32명)가 공존질환을 갖고 있었으며, 22.7%에서 고위험음주를 보였다. 수면클리닉에 내원한 이유는 잠들기 힘들고 중간에 자주 깸, 낮에 피곤하고 졸림, 불규칙한 수면시간, 악몽을 자주 꿈, 코골이와 수면 중 숨막힘 등의 순서였고, 93.2%에서 불면증을 인식하고 있었고, 가족 친지, 방송, 인터넷 등을 통해 본인이 불면증에 대한 지식을 얻게 되었다고 하였다. 불면증의 치료에 대해서는 70.5%가 약물치료를 떠올렸고, 이에 대한 정보는 인터넷과 의료진을 통해 주로 얻고 있었으며 불면증의 비약물학적인 치료방법에 대해 52.3%가 들어본 적이 없다고 하였다. 불면증의 치료선호도를 묻는 질문에 45.5%가 특별한 선호도 없이 의사의 권유대로 따르겠다고 하였고, 불면증의 공존질환 중 우울증, 신체질환, 알코올사용장애을 알고 있는지를 묻는 질문에 대해 각각 75%, 50%, 38.6%의 응답률을 보였다. 수면제 복용 시 의사의 지침을 준수해야 한다는 것에 대해서는 75%에서 알고 있었지만, 전체 응답자의 68.2%가 수면제 처방에 대해 걱정을 하고 있었고 이들 중 70%가 약물의존에 대해 걱정된다고 하였다. 결 론 : 내원자의 56.8%가 내원전 타의료기관에서 수면장애로 치료를 받고 왔음에도 불구하고, 불면증의 치료, 특히 비약물학적인 치료에 대한 잘 알고 있지 못했으며, 본인의 수면제 복용여부와 상관없이 수면제에 대해서는 약물의존에 대한 걱정을 많이 하고 있었으나 상대적으로 불면증과 공존질환으로서의 알코올 사용문제에 대해서는 간과하고 있었다. 향후 일선 일차의료담당자의 불면증치료에 대한 이해증진 및 표준화된 불면증치료안의 개발이 시급할 것으로 생각된다. 또한 알코올 사용장애에 대한 구체적인 평가가 초기 면담에서 반드시 필요하다고 하겠다.