• 한국생활과학회지
• /
• 제17권5호
• /
• pp.807-819
• /
• 2008

The purpose of this study was to find out the factors which were related to the delinquent behaviors among 2nd years high school in Geoje, Korea. The subjects were 618 high school students. Data were collected by self-reported questionnaires from March to April, 2007. Data were analyzed by SPSS WIN 12.0 program with mean, standard deviation, t-test, ANOVA, Kruskal-Wallis test, Scheffe's test, Pearson's correlation, and stepwise multiple regression. Students' delinquent behaviors differed by experience of smoking, experience of drinking, harmony of family, mother's education, father's smoking mother's smoking, academical class, satisfaction of school-life, friends who smoked, drank alcohol, did drugs, and punished friends. Students' stress and depression had positive correlation with their delinquent behaviors. The result of stepwise multiple regression showed that punished friends, experience of smoking, depression, father's smoking satisfaction of school-life were significant related factors to delinquent behaviors among high school students. It is necessary for home, school, and community to cooperate with each other in preventing high school students from delinquent behaviors.

• 생물정신의학
• /
• 제8권2호
• /
• pp.258-265
• /
• 2001

Objectives : Chronic alcohol consumption has been known to result in various neurocognitive deficits. Many neuropsychological studies revealed that the major disturbances occurred in the executive function, learning and short-term memory, visuospatial performance function, perceptuo-motor skills, and abstraction and problem solving abilities. This study was done to identify which cognitive areas might be mainly affected. Methods : The cognitive disturbance was evaluated using the Korean Version of the Mini Mental State Examination(MMSEK) and the 7 Minute Screen(7MS) in male inpatients with alcohol dependence(N=3 : as well as in age and education level matched healthy male controls(N=30). Four individual tests of the 7MS were consisted of the Benton Temporal Orientation Test, the Enhanced Cued Recall, the Clock Drawing and the Category Fluency. Results : 1) The average scores of four individual test of the 7MS for the alcoholics were $2.77{\pm}4.38$ for the Benton Temporal Orientation Test, $13.90{\pm}2.02$ for the Memory Test(the Cued Recall $6.77{\pm}1.94$, the Uncued Recall $7.10{\pm}2.45$), $5.84{\pm}1.86$ for the Clock Drawing, and $12.58{\pm}3.29$ for the Category Fluency. Except the Benton Temporal Orientation Test, there were statistically significant differences between test scores of alcoholics and those of controls(p<0.01). 2) The alcoholics who had MMSE-K score <24 were 9.68%. The average(${\pm}S.D.$) score of the MMSE-K for the patient group($27.23{\pm}2.62$) was significantly(p<0.001) lower than that of the healthy controls($29.20{\pm}1.24$). There were no statistically significant differences between four individual test scores of the 7MS of alcoholics with the MMSE-K score <24(N=3) and those of alcoholics with the MMSE-K score ${\geq}24$(N=28). 3) Four individual test scores of the 7MS seemed to have statistically significant association with such variables as MMSE-K, duration of alcohol drinking, blood magnesium concentration, liver function and thyroid function. Conclusion : Mild deficits of cognitive areas such as orientation, memory, visuospatial abilities and verbal fluency could be found in alcohol dependence.

• 대한약리학회지
• /
• 제9권1호
• /
• pp.23-37
• /
• 1973

This paper presents the effect of chronic administration of psychotropic drugs on rats. The experimental animals were litter mates (average initial body weight $47{\pm}1.1g$) whose mother were bred at our laboratory. Each litter mate was treated as one group. Control animals were treated with tap water and each experimental group was treated with caffeine citrate 0.1%, nialamide 0.1%, ethyl alcohol 2.5%, phenobarbital sod. 0.1%, diphenylhydantoin 0.1%, chlorpromazine 0.1%, reserpine 0.005%, diazepam 0.01%, chlorpheniramine 0.01% solutions respectively in drinking water over a period of ten weeks. All rats were allowed food and drinking water ad libitum. The mortality rate and the per cent increase of body weight were recorded weekly throughout the course of the experiment. The effects of above agents on the pentobarbital sleeping time, gastric secretion, and brain and liver weights were studied at the end of ten weeks treatment. The obtained results are summarized as follows: 1. Mortality rate was highest in the groups treated with phenobarbital and chlorpromazine respectively. Through the experimental period (ten weeks), the mortality rate was higher in earlier stage than in the later period. 2. During the period of prolonged administration of psychotropic drugs, only diazepam treated group showed remarkable difference in per cent increase of body weight from the control group of rats. 3. Acute treatment with psychotropic drugs delayed the onset of pentobarbital sleeping time. In contrast, the sleeping time was significantly shortened (p<0.001) when the rats were treated chronically with those agents. 4. The effects of chronic treatment with phenobarbital or diphenylhydantoin on the gastric secretion are as follows: the total acidity was remarkably decreased while the pH was increased. 5. The brain weight was significantly decreased in the ethyl alchol and in the chlorpheniramine treated groups, in the mean time, there was no change in liver weight treated with any psychotropic drugs.

• Journal of Preventive Medicine and Public Health
• /
• 제57권3호
• /
• pp.288-297
• /
• 2024

Objectives: This study explored the prevalence and predictors of alcohol and cannabis co-use among 9263 Filipino adolescents, using data from the 2019 Global School-based Student Health Survey (GSHS). Methods: We conducted a cross-sectional secondary analysis of the GSHS, targeting adolescents aged 13-17 years and excluding cases with incomplete data on alcohol and cannabis use. Our analysis employed the bivariate chi-square test of independence and multivariable logistic regression using Stata version 18 to identify significant predictors of co-use, with a p-value threshold set at 0.05. Results: The weighted prevalence of co-users was 4.2% (95% confidence interval [CI], 3.4 to 5.3). Significant predictors included male sex (adjusted odds ratio [aOR], 4.50; 95% CI, 3.31 to 6.10; p<0.001) and being in a lower academic year, specifically grade 7 (aOR, 4.08; 95% CI, 2.39 to 6.99; p<0.001) and grade 8 (aOR, 2.20; 95% CI, 1.30 to 3.72; p=0.003). Poor sleep quality was also a significant predictor (aOR, 1.77; 95% CI, 1.29 to 2.44; p<0.001), as was a history of attempted suicide (aOR, 5.31; 95% CI, 4.00 to 7.06; p<0.001). Physical inactivity was associated with lower odds of co-use (aOR, 0.45; 95% CI, 0.33 to 0.62; p<0.001). Additionally, non-attendance of physical education classes (aOR, 1.48; 95% CI, 1.06 to 2.05; p=0.021), infrequent unapproved parental checks (aOR, 1.37; 95% CI, 1.04 to 1.80; p=0.024), and lower parental awareness of free-time activities (aOR, 0.63; 95% CI, 0.45 to 0.87; p=0.005) were associated with higher odds of co-use. Factors not significantly linked to co-use included age group, being in grade 9, always feeling lonely, having no close friends, being bullied outside school, and whether a parent or guardian understood the adolescent's worries. Conclusions: The findings highlight the critical need for comprehensive interventions in the Philippines, addressing not only physical inactivity and parental monitoring but also focusing on sex, academic grade, participation in physical education classes, sleep quality, and suicide attempt history, to effectively reduce alcohol and cannabis co-use among adolescents.

• Nutrition Research and Practice
• /
• 제4권4호
• /
• pp.323-331
• /
• 2010

The aim of this study was to analyse effects that the degree of depression have on the life style variables, nutrient intake, iron indices and pregnancy outcome. Subjects were 114 pregnant women who were receiving prenatal care at a hospital in Seoul. We collected data for general characteristics and lifestyle variables from general survey instrument and for depression score from the questionnaire on depression. Dietary intakes of subjects were estimated by 24 hour dietary recall method. Also we analysed iron indices and pregnancy outcomes. We classified subjects by 10 point, which was the average depression score, into two groups [Low depression score group (LS) : High depression score group (HS)]. As to the intakes of total calcium, plant-calcium, plant-iron, potassium, total folate and dietary folate, LS group was far higher than HS group (P < 0.05, P < 0.05, P < 0.01, P < 0.001, P < 0.05, and P < 0.01, respectively). As to pre-pregnancy alcohol drinking, LS group had 41.9% in non-drinker, which was far higher than 28% in HS group in non-drinker (P < 0.05). As for drinking coffee during pre-pregnancy, pregnant women who don’ drink coffee in LS group took 43.6%, which was higher than 38% in HS group (P < 0.01). Regarding delivery type, the cesarean section in LS group (18%) was significantly lower than that in HS group (45%) (P < 0.01). Bivariate analysis showed that birth weight was significantly associated with the gestational age (P < 0.01). The pregnant women with higher depression score tended to have undesirable life habit, which might affect negative pregnancy outcomes. A better understanding of how depression and intake of nutrients work together to modulate behavior will be benefit nutritional research.

• 대한지역사회영양학회지
• /
• 제12권5호
• /
• pp.592-605
• /
• 2007

Undernutrition could be a significant deterrent to healthy aging and could negatively affect health outcomes in elderly. This study aimed to assess health-related factors which are associated with nutritional risks in middle-aged and elderly individuals by a cross-sectional study. Interviews were conducted with 2660 subjects (847 males, 1813 females), aged 50 years and over, in 15 cities in Korea. Data on food intake were obtained through a validated semi-quantitative food frequency questionnaires. Nutritional status were analyzed according to health-related factors including cigarette smoking, alcohol drinking, exercise, stress and depression level. Less regular exercise was associated with a higher likelihood of a poor nutrition [odds ratio (OR) 1.94; 95% confidence intervals (CI) 1.43-2.65] of middle-aged and elderly male subjects. Cigarette smoking (OR 1.84; 95% CI 1.24-2.71), less exercise (OR 2.58; 95% CI 2.07-3.21), stress (OR 1.73; 95% CI 1.36-2.22), and depression (OR 1.34, 95% CI 1.08-1.67) of middle-aged and elderly female subjects was associated with a higher likelihood of a poor nutrition. The results of the multiple regression analysis showed that less exercise proved to be the strongest predictors for the poor nutrition, followed by stress, smoking, and depression (model $R^2= 9.0%$). It suggests that guidance to promote regular exercise, to quit smoking, to minimize stress and depression level might help to improve nutritional status of middle-aged and elderly in Korea. These findings also suggest that having recommendable health behaviors are beneficial to the good nutrition of subjects aged 50 years and over.

• Applied Microscopy
• /
• 제39권4호
• /
• pp.311-317
• /
• 2009

본 연구는 투어마린 소재와 전기적인 방전을 통해 물의 성질을 변화시킨 투어마린이온활성수를 이용하여 간보호 효과, 비만 예방 효과, 숙취제거 효과를 확인하기 위해 시행되었다. 고지방식이로 비만을 유도한 ICR 마우스에서 투어마린이온활성수를 급이한 실험군은 정수물을 급이한 대조군과 비교하여 사료섭취량이 비슷하고 음수량이 더 적었지만 체중증가는 대조군에 비하여 억제되어 13주에는 유의한 차이를 보여줌으로써 비만 예방 효과를 나타내었다(P<0.05). 사염화탄소로 간독성을 유발시킨 생쥐를 이용하여 간보호 효과를 관찰한 실험에서, 실험군의 aspartate aminotransferase (AST)와 alanine aminotransferase (ALT)는 대조군과 비교하여 평균적인 차이를 나타내었으며, 간의 조직학적 관찰에서 괴사를 비롯한 병리학적 병변이 감소한 것으로 나타났다. S-D rats을 이용한 숙취 실험에서는 실험군이 대조군에 비해 혈중알콜농도가 유의하게 낮았으며(P<0.01), 알콜 대사와 관련된 항산화 효소인 glutathione-S transferase (GST)는 활성이 증가한 것으로 관찰되었고(P<0.05), 간기능 지표인 AST와 ALT는 상대적인 감소현상을 보였다. 이와 같은 결과는 투어마린이온활성수의 음용이 동물의 항산화 체계에 영향을 미침으로써 간조직을 보호하고 알콜 분해를 향상시킨 것으로 판단되며, 그 결과 숙취해소에 어느 정도 효과가 있을 것으로 판단된다. 투어마린이온활성수의 효능과 관련된 기전은 아직 과학적 검증에 어려움이 있으나, 물에 전달된 투어마린의 원적외선에너지나 전기적 영향으로 인하여 물분자의 결합력과 분자 구조 또는 클러스터의 크기에 변화를 일으켰기 때문으로 판단된다. 사용된 투어마린이온활성수는 음용안전성이 확보된 물로서 효과적인 기능수로 개발될 가능성을 가지며, 유효성과 관련된 기전은 더 연구될 필요성이 있다.

• Journal of Preventive Medicine and Public Health
• /
• 제50권6호
• /
• pp.377-385
• /
• 2017

Objectives: Although mercury (Hg) exposure is known to be neurotoxic in humans, its effects on liver function have been less often reported. The aim of this study was to investigate whether total Hg exposure in Korean adults was associated with elevated serum levels of the liver enzymes aspartate aminotransferase (AST), alanine transaminase (ALT), and gamma-glutamyltransferase (GGT). Methods: We repeatedly examined the levels of total Hg and liver enzymes in the blood of 508 adults during 2010-2011 and 2014-2015. Cross-sectional associations between levels of blood Hg and liver enzymes were analyzed using a generalized linear model, and nonlinear relationships were analyzed using a generalized additive mixed model. Generalized estimating equations were applied to examine longitudinal associations, considering the correlations of individuals measured repeatedly. Results: GGT increased by 11.0% (95% confidence interval [CI], 4.5 to 18.0%) in women and 8.1% (95% CI, -0.5 to 17.4%) in men per doubling of Hg levels, but AST and ALT were not significantly associated with Hg in either men or women. In women who drank more than 2 or 3 times per week, AST, ALT, and GGT levels increased by 10.6% (95% CI, 4.2 to 17.5%), 7.7% (95% CI, 1.1 to 14.7%), and 37.5% (95% CI,15.2 to 64.3%) per doubling of Hg levels, respectively, showing an interaction between blood Hg levels and drinking. Conclusions: Hg exposure was associated with an elevated serum concentration of GGT. Especially in women who were frequent drinkers, AST, ALT, and GGT showed a significant increase, with a significant synergistic effect of Hg and alcohol consumption.

• 한국노년학
• /
• 제34권2호
• /
• pp.229-246
• /
• 2014

본 연구는 지역사회 내 제2형 당뇨병 노인을 대상으로 성격유형과 당뇨병 관련 스트레스에 따른 당뇨병 자기관리 행위 간의 관계를 규명하는데 목적을 두고 시행되었다. 본 연구는 서술적 조사연구로 노인복지관을 이용하는 65세 이상 노인 중 제2형 당뇨병이 있는 180명을 대상으로 실시하였다. 연구 결과, 일반적 특성과 질병 관련 특성에 따라 당뇨병 자기관리 행위의 차이가 있는 것으로 나타났다. 그리고 대상자 성격유형에 따라 당뇨병 자기관리 행위에는 유의한 차이가 있었고(p<.001), 주도형이 안정형과 신중형보다 자기관리 행위 이행수준이 낮았다. 특히, 자기관리 행위 하위영역 중 발 관리 영역에서 성격유형별 차이가 있었는데(p<.001), 주도형이 안정형과 신중형보다 유의하게 낮았다. 그리고 주도형 성격유형, 경구 혈당강하제를 투약하는 경우, 음주를 하는 경우가 당뇨병 자기관리 행위에 영향을 미치는 주요변수로 나타났다(수정된 R²=16%). 따라서 제2형 당뇨병 노인을 대상으로 하는 자기관리 교육 중재 시 성격유형, 경구 혈당강하제 투약 여부, 음주 여부가 고려되어야 하고, 자기관리 행위 이행이 상대적으로 낮은 주도형 성향을 가지고, 경구 혈당강하제 투약을 하며, 음주를 하는 당뇨병 노인을 위한 효과적인 교육중재 프로그램 개발이 필요하다.

• Journal of Preventive Medicine and Public Health
• /
• 제28권2호
• /
• pp.497-510
• /
• 1995

This study was carried out to assess work ability of manufacturing workers and managerial workers. Subjects were 446 manufacturing workers and 278 managerial workers employed in Gumi industrial complex and the observation period was for 1 month(February to March), 1995. In this study, as a questionnaire for the assessment of work ability, we used the Work Ability Index(WAI) which was developed by Institute of Occupational Health in Finland. Major findings obtained from this study were as follows ; WAI was poor in lower economic condition, shift work, irregular diet group(p<0.05). There were no evident trends of WAS in sex, educational level, obesity index, exercise, smoking, and alcohol drinking. In the groups of sensitive to perception of stress, other industrial classification except textile and electronics, the more than 9 hours work, the evident trends of poor WAS were observed(p<0.01). In the groups of $30\sim39$ years old, $40\sim49$ years old, unmarried, high school, shift work, standard body weight, and regular .diet, WAI between manufacturing workers and managerial workers was significantly different(p<0.01) and WAI of managerial worker was worse than that of manufacturing worker.