• 제목/요약/키워드: Alcohol Drinking in College

검색결과 488건 처리시간 0.032초

Tumor necrosis $factor-\;{\alpha}$, interleukin-6 and interleukin-10 polymorphisms in the Korean stroke patients

  • Kim, Kyung-Min;Lee, Sang-Hoon;Lee, Jae-Dong;Choi, Do-Young
    • Journal of Acupuncture Research
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    • 제22권2호
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    • pp.1-12
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    • 2005
  • Objective: With the onset of stroke, white blood cells release several proinflammatory cytokines, including interleukin (IL)-6, IL-10, and tumor necrosis factor $(TNF)-{\alpha}$. It has been proven in previous studies that the release of these cytokines is related to the extent of damage to the brain and to overall prognosis. However, no studies have yet been performed to determine the connection with IL-6 and IL-10. Thus, this study is performed to see whether polymorphisms of IL-6, IL-10, and $TNF-{\alpha}$ genes that show increased serum concentration with the onset of stroke are related to stroke attack in Koreans. Methods : Peripheral blood samples derived from patients with stroke (n=100) and healthy controls (n=100) were taken under informed consent. In subjects with stroke, blood samples were obtained within 24 hours of stroke onset. Genomic DNA was isolated using the Wizard DNA Purification Kit (Promega, Madison, WI). Results : 1. Subjects with Heterozygote (GA) and Homozygote (AA) $TNF-{\alpha}$ gene types showed 2.433 and 20.457 times higher risks of being attacked by stroke, respectively, compared to subjects with wild type (GG) $TNF-{\alpha}$ gene type. The data was still statistically significant after adjusting for age, sex, history of smoking, and history of alcohol drinking. 2. Subjects with Homozygote (CC) IL-6 gene type showed 182.033 times higher risk of being attacked by stroke, compared to subjects with wild type (GG) IL-6 genes. This data was statistically insignificant (p=0.700). The data was still statistically insignificant after adjusting for age, sex, history of smoking, and history of alcohol drinking. 3. Subjects with Heterozygote (GA) and Homozygote (GG) IL-10 gene types showed 8.785 and 3.303 times higher risks of being attacked by stroke, respectively, compared to subjects with wild type (AA) IL-10 genes. The data was still statistically insignificant after adjusting for age, sex, history of smoking, and history of alcohol drinking. Conclusion : Our results suggest that the investigated $TNF-{\alpha}$ and IL-10 gene polymorphisms play an important role in stroke attack, but IL-6 gene polymorphism has not been found to associated with stroke.

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우리나라 성인의 건강행태군집 유형과 관련요인 (Types of Health Behavior Clusters and Related Factors among Korean Adults)

  • 문성미
    • 디지털융복합연구
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    • 제12권8호
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    • pp.397-410
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    • 2014
  • 본 연구의 목적은 한국 성인의 건강행태군집 유형을 확인하고 이와 관련된 요인들을 파악하는 것이다. 이를 위해 2009년도 국민건강영양조사 자료를 이차분석 하였다. 신체활동, 흡연, 음주 변수를 이용하여 19세부터 64세까지 성인 대상자의 건강행태유형을 군집분석으로 파악하였고 이 유형들과 인구사회학적 특성 및 건강상태의 연관성을 확인하기 위해 SPSS WIN 21 복합표본설계 분석모듈을 이용하여 카이제곱 검정과 다항로지스틱 분석을 실시하였다. 한국 성인의 건강행태군집 유형은 건강증진군, 흡연군, 음주군, 수동적 태도군, 그리고 위험행위군의 총 5개 유형으로 분류되었고 수동적 태도군에 속하는 대상자의 빈도가 47.7%로 가장 높았다. 인구사회학적 특성, 고혈압, 그리고 우울증상 경험은 대상자가 건강증진군 보다는 나머지 4개의 건강위해 행위군에 속하는 것과 유의한 연관을 보이는 변수였다. 본 연구결과는 건강증진프로그램이 단일 행위에 초점을 맞추기 보다는 대상자의 건강행태유형에 초점을 맞추어 통합적으로 기획되어야 함을 보여주고 있다. 추후연구에서는 인구사회학적 특성과 건강상태뿐만 아니라 사회적 지지나 사회적 네트워크와 같은 사회심리적 요인과 건강행태유형과의 관계를 규명하는 것이 필요하다.

건강행위 및 주관적 구강증상이 주관적 구강건강상태에 미치는 영향 (Influences of health behaviors and perceived oral symptoms on subjective oral health status)

  • 원영순;박소영
    • 한국치위생학회지
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    • 제13권5호
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    • pp.787-795
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    • 2013
  • Objectives : The aim of the study is to investigate the possible influences of health behaviors and oral symptoms on subjective oral health status and to provide basic data for the development of oral health education programs. Methods : Subjects were 274 nursing home workers in Jeollabukdo, Korea. A self- reported survey was carried out. Results : Eighty four persons (30.7%) subjectively perceived their subjective oral health was good in the meanwhile forty nine persons (17.9%) reported poor oral health status. Health behaviors had much influence on their subjective oral health status. Good subjective oral health status coincided with quitting od smoking and drinking alcohol. Periodontal diseases and dental caries, and tooache had bad influences on subjective oral health status. Conclusions : Quitting program for smoking and drinking alcohol will make the nursing home workers in good healthy oral health status.

한국인 알코올중독 환자의 예후인자에 관한 연구 : 심리적, 사회적, 생물학적 요인을 중심으로 (A Study for The Prognostic Indicators of Korean Alcoholics in Psychological, Social and Biological Aspects)

  • 성상경;장환일
    • 생물정신의학
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    • 제2권2호
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    • pp.218-236
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    • 1995
  • The author studied prognostic indicators of sixty Korean male alcoholics in psychological, social and biological aspects who were divided into abstinent and drinking groups. Thirty patients were assigned to each group. They were controlled in age and sex. Both groups were compared in terms of the demographic characteristics, past drinking history, treatment history, famaily history, ego strength and personality factors differences and distribution of dopamine $D_2$ receptor gene Al allele. Also the author studied relation of clinical course, alcoholic family history and dopamine $D_2$ receptor gene Al allele in both groups. The results were as follows; 1) The abstinent group had higher rate of married state, higher economic status, longer education years and maintained more stable job than the drinking group. But made no differences in occupation and religion. 2) The abstinent group showed higher rate of living with family members than the drinking group, and wives and fellows of the alcoholics anonymous were important factors for maintenance of abstinence. Family loading and parent's characters were not different. 3) The abstinent group had longer maximal length of abstinence but mean amount of alcohol consumption per day were larger than the drinking group. But there were no differences in duration of past drinking, drinking pattern, main drinking time, first drinking age and preference of the kind of alcoholic beverage in the past drinking history. 4) The abstinent group showed stronger treatment motivation, absolute abstinence in treatment goal, more voluntary adimission and maintained longer therapeutic relationship otter discharge than the drinking group. But both groups showed negative attitude toward antabuse therapy. 5) The abstinent group had higher mean score in ego strength scale than the drinking group. 6) In the personality factor questionnaire, the abstinent group showed strong laugh poise and the trait of praxernia, conservatism personality but the drinking group showed tough poise, the trait of weak ego strength(unstableness) and tough mindedness personality. 7) In comparision of dopamine $D_2$ receptor gene A1 allele, the prevalence of A1 allele was seventy percent and the frequency was 0.38 in the abstinent group. The prevalence of A1 allele was sixty percent and the frequency was 0.42 in the drinking group. Both groups were not significantly different in A1 allele prevalence and frequency. 8) In comparision of dopamine $D_2$ receptor gene A1 allele according to alcoholic family history, the prevalence of A1 allele was seventy percent and the frequency was 0.43 in the family history positive group. The prevalence of A1 allele was sixty-one percent and the frequency was 0.38 in the family history negative group. Both groups were not significantly different in A1 allele prevalence and frequency. In comparision of past drinking history according to alcoholic family history, the family history positive group showed earlier first drinking and problem drinking, but the family history negative group hod longer duration of past drinking. The mean amount of alcohol consumption per day, the longest duration of abstinence and Alcoholism Screening Test of Seoul Natoinal Mental Hospital(NAST) results were not significant. In conclusion, the results suggest that successful prognostic indicators of Korean alcoholics are married state, higher economic status, longer education years, stable job, living with family members, longer abstinence during past drinking history, strong treatment motivation, absolute abstinence in treatment goal, voluntary adimission, maintained therapeufic relationship, strong ego strength and the trait of praxernia, conservatism personality. But occupation, religion, alcoholic family history, parent's characters, duration of past drinking, drinking pattern, main drinking time, first drinking age, preference of the kind of alcoholic beverage, attitude to antabuse therapy and distribution of dopamine $D_2$ receptor A1 allele were not significantly related to the prognostic indicators of Korean alcoholics.

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일부 농촌지역 주민들의 부부간 고혈압 위험요인의 일치성 (Concordance of Hypertension in Husband and Wife Living in a Rural Area)

  • 유동균;이소영;이태용;이은희
    • 한국산학기술학회논문지
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    • 제10권3호
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    • pp.634-641
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    • 2009
  • 보건복지가족부 질병관리본부의 건강관리를 위한 지역 코호트사업으로 금산군 1개읍 9개면에 거주하는 만 40세이상부터 70세까지의 주민 중 본 연구에 참여의사를 밝힌 임의 추출된 총 2,007명(남: 868명, 여: 1,139명) 중 부부가 함께 조사된 297쌍(594명)을 대상으로 배우자의 고혈압 위험요인이 상대 배우자의 고혈압에 미치는 영향을 조사한 결과는 다음과 같다. 고혈압 위험요인은 아내가 대사증후군이 있는 경우(OR=2.879), 현재 음주자(OR=1.892)에서 높았다. 아내 고혈압에 대한 남편의 고혈압 위험요인은 연령(OR=1.037), 비만(OR=1.922), 대사증후군(OR=4.100), 중성지방(OR=1.793)에서 높았다. 결론적으로 농촌지역 부부들에서 함께 공유하는 공간과 시간에서 고혈압에 영향을 주는 요인은 연령, 체질량지수, 대사 증후군이 중요하므로 이에 대한 관리가 필요하다고 본다.

추골기저동맥 일과성 허혈발작에서 뇌간청각유발전위변화에 영향을 미치는 인자 (Factors Influencing the Changes of BAEPs in Vertebrobasilar Transient Ischemic Attacks)

  • 박영혁;유봉구;김광수;유경무
    • Annals of Clinical Neurophysiology
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    • 제2권2호
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    • pp.101-106
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    • 2000
  • Background and Purpose : Brainstem auditory evoked potentials(BAEPs) are responses of the brainstem by auditory stimulation. Vertebrobasilar transient ischemic attacks is the disease that occurs by insufficient circulation in the region of brainstem. The purpose of this study is to know the factors influencing the changes of BAEPs in vertebrobasilar transient ischemic attacks. Methods : The subject of study was 96 patients diagnosed as vertebrobasilar transient ischemic attacks. Patients were divided into two groups according to the BAEPs findings. Their age, sex, presence of hypertension, diabetes, hyperlipidemia, heart disease, neurologic findings, previous stroke, previous vertebrobasilar transient ischemic attacks, smoking and alcohol drinking, and time period between symptom onset and testing were compared. Results : There were no significant differences in age, sex, and presence of hypertension, diabetes, hyperlipidemia, heart disease, previous stroke history, previous vertebrobasilar transient ischemic attack, smoking, and alcohol drinking between two groups. The presence of abnormal neurologic findings in the first examination and time period between symptom onset and testing were significantly different between normal BAEPs group and abnormal BAEPs one(P<0.05). Conclusions : The factors influencing the changes of BAEPs were presence of abnormal neurologic findings and time period between symptom onset and testing. These findings suggest that BAEPs test should be performed in acute stage of ischemic attack.

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Rhinovirus Associated Severe Respiratory Failure in Immunocompetent Adult Patient

  • Kim, Kiwook;Song, Yeon Han;Park, Joo-Hyun;Park, Hye Kyeong;Kim, Su Young;Jung, Hun;Lee, Sung-Soon;Koo, Hyeon-Kyoung
    • Tuberculosis and Respiratory Diseases
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    • 제77권3호
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    • pp.132-135
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    • 2014
  • Rhinovirus infection is typically associated with the common cold and has rarely been reported as a cause of severe pneumonia in immunocompetent adults. A 55-year-old previous healthy woman, who consumed half a bottle of alcohol daily, presented with respiratory failure after one week of upper respiratory infection symptoms. Radiography revealed bilateral, diffuse ground glass opacity with patchy consolidation in the whole lung field; bronchoalveolar lavage fluid analysis indicated that rhinovirus was the causative organism. After five days of conservative support, the symptoms and radiographic findings began to improve. We report this rare case of rhinovirus pneumonia in an otherwise healthy host along with a review of references.

남자대학생의 흡연 및 식사습관에 따른 인체 임파구 SCE 빈도 수의 변화 (The Variations of the SCE Frequency of Human Lymphocytes by Smoking Habits and Dietary Factors in College Students)

  • 조성선
    • Journal of Nutrition and Health
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    • 제26권3호
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    • pp.313-324
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    • 1993
  • Sister chromatid exchange(SCE) has recently become a common cytogenic assay system for detecting exposure to chemical mutagens and carcinogens. One application of SCE is the monitoring of populations believed to be exposed to such agents. A cross-sectional study of SCE frequency in peripheral blood lymphocytes from 40 college students aged 18 to 26 years was conducted. The effects of cigarette smoking alcohol and coffee consumption, dietary and environmental factors on SCE were assessed. A mean spontaneous SCE per cell for the smokers(4.88$\pm$0.17). The SCE levels of the smokers were associated with the personal smoking amount ; the observed increase in the SCE frequency correlated with the number of cigarettes smoked per day (P<0.05). There was no effect of age on SCE. There were positive linear relationship between SCE and food frequency score of meat and fish group (P<0.05) or instant food group(P<0.01) in non-smokers. But in smokers, a significant inverse association between SCE and food frequency score of green and yellow vegetable group(P<0.05). Alcohol intake produced a significant increase(P<0.01) of SCE in comparison with the mean SCE for those not drinking alcohol in combine subjects. Other dietary parameters, including coffee intake, use of artificial sweetners and processed foods, did not show any increase in SCE. SCEs were inversely related to blood glucose and serum cholesterol levels of the combine subjects. No significant correlations were found between SCE frequencise and any other hematological parameters of the subjects.

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Guinea pig에서 alcohol과 paraquat에 의한 갑상선 독성에 미치는 selenium의 방어 효과 (Protective effect of selenium on alcohol and/or paraquat-induced thyroid toxicity in guinea pigs)

  • 김진상;강형섭
    • 대한수의학회지
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    • 제36권1호
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    • pp.209-219
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    • 1996
  • This study examined the effect of alcohol(AL) and/or paraquat(PQ) on serum TSH, thyroid hormones and enzyme activities, and the protective effect of selenium(SE) againse alcohol and/or paraquat-induced thyroid toxicity in guinea pigs. The experomental group consisted of control, 15% alcohol(AL), 4ppm sodium selentite(SE), 200ppm paraquat(PQ), AL+PQ, AL+SE, PQ+SE and AL+PQ+SE mixed in drinking water-fed guinea pigs for 4 weeks. The morphological changes of thyroid gland were studies on paraffin-embedded sections stained with H-E stain. Body weight losses, high serum concentration in TSH and cholesterol, and low values on triiodothyronine($T_3$), thyrozine($T_4$), free $T_4$ and alkaline phosophatase(ALP) were produced in the groups fed AL and/or PQ. We also noted that AL+PQ-fed group was marked increase in serum TSH. In AL or AL+PQ-fed groups when cpmpared to control group had increased the ratio of thyroid weight to body weight(ratio Twt/Bwt), whereas the ratio Twt/Bwt was decresed in SE or PQ-fed groups. However, the serum TSH, $T_3$,$T_4$ free $T_4$ and cholesterol values, and the ratio Twt/Bwt were reversed in groups given the combination of SE, compared with AL and/or Pq-fed groups, also ALP values were reversed in groups given the combination of SE, compared with AL or AL+PQ-fed groups. In microscope, morphological changes showed a remarkable between the AL or PQ-fed group and controls. In AL+PQ+SE-fed guinca pig, follicular colloid is high density in thyroid follicle and increased in connective tissue around the thyroid cells, and thyroidal epithelia were composed of cuboidal or columnar epithelium. The indicated that the morphological changes of thyroid were direct action in the thyroid cell. The results of this study confirmed that the toxic effect of AL or PQ on thyroid occur independently of changes in liver function, and that SE confers marked protection against AL or PQ-induced thyroid toxicity.

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급성기 중풍 환자의 사상체질별 분포와 식생활습관 간의 상관성에 대한 연구 (A Correlation Research of Diet and Lifestyle According to Sasang Constitution in Acute Stroke Patients)

  • 김용형;최인영;마미진;강아미;최동준;한창호;이원철;전찬용;조기호;최선미
    • 대한한방내과학회지
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    • 제28권4호
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    • pp.741-750
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    • 2007
  • Objective : This study investigated the relationship between diet and lifestyle and Sasang constitution (SC) in acute stroke patients. Methods : From October 2005 to March 2007, 379 acute stroke patients were included. Patients were hospitalized within 14 days after the onset of stroke at DongGuk University International Hospital, Kyungwon University In-cheon Oriental Medical Hospital or Department Cardiovascular and Neurologic Diseases (stroke center), Kyung Hee University Oriental hospital. We assessed the type of SC of acute stroke patients by Questionnaire for Sasang Constitution Classification II (QSCC II). We investigated general characteristics, stroke types, dietary preferences (meat, sea food, fast food, alcohol drinking, coffee and green tea drinking) and lifestyle (smoking, exercise) according to SC. Results : This study showed that out of the total patients, the proportion of So-yang to Tae-eum to So-eumwas equal to 2.6 to 2 to 1. Of note, this study showed a higher proportion in age of So-eum & weight of Tae-eum. The ratio of cerebral hemorrhage to cerebral infarction was 1 to 9. SVO, LAA, SUE are the 3 types of cerebral infarction classified by TOAST; SVO ranked the highest while SUE ranked the lowest in all constitutions. There were no significant differences between So-yang and Tae-eum in the aspect of the preference for meat, but the majority of So-eum displayed high preferences for seafood. In the aspect of alcohol drinking and smoking history, So-yang recorded significantly bigger proportion while So-eum & Tae-eum patients represented a bigger proportion than So-yangin the aspect of no exercise habits. Conclusion : According to the result above, we could observe the general disposition of various characteristic distributions according to SC of acute stroke patients. Also, we could observe a relationship between diet and lifestyle and Sasang constitution (SC) in acute stroke patients. Further studies will be needed to better understand the relationship between diet and lifestyle and Sasang constitution (SC) in acute stroke patients.

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