• 제목/요약/키워드: Alcohol Dependence

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A Longitudinal Study of the Relationship Between Health Behavior Risk Factors and Dependence in Activities of Daily Living (건강위험행태인자와 일상생활 의존성과의 관련성에 대한 추적자료 분석)

  • Jung, Sang-Hyuk;Ostbye, Truls;Park, Kyoung-Ok
    • Journal of Preventive Medicine and Public Health
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    • v.39 no.3
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    • pp.221-228
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    • 2006
  • Objectives: The purpose of this study was to shed further light on the effect of modifiable health behavior risk factors on dependence in activities of daily living, defined in a multidimensional fashion. Methods: The study participants were 10,278 middle aged Americans in a longitudinal health study, the Health and Retirement Survey (HRS). A multi-stage probability sampling design incorporating the effect of population sizes (Metropolitan and non-metropolitan), ethnicity (the non- Hispanic White, the Hispanic, and the Black), and age (age 51-61) was utilized. Basic Activities of Daily Living (ADL) were measured using five activities necessary for survival (impairment in dressing, eating, bathing, sleeping, and moving across indoor spaces). Explanatory variables were four health behavior risk factors included smoking, exercise, Body Mass Index (BMI), and alcohol consumption. Results: Most participants at baseline were ADL independent (1992). 97.8% of participants were independent in all ADL's at baseline and 78.2% were married. Approximately 27.5% were current smokers at baseline, and the subjects reported moderate or heavy exercise were 74.8%. All demographic characteristics and behavioral risk factors were significantly associated with the ADL status at Wave 4 except alcohol consumption. Risk behaviors such as current smoking, sedentary life style and high BMI at Wave 1 were associated with ADL status deterioration; however, moderate alcohol consumption tended to be more related to better ADL status than abstaining at Wave 4. ADL status at Wave 1 was the strongest factor and the next was exercise and smoking affecting ADL status at Wave 4. People who were in ADL dependent at Wave 1 were 15.17 times more likely to be ADL dependent at Wave 4 than people who were in ADL independent at Wave 1. Concerning smoking cigarettes, people who kept only light exercise or sedentary life style at Wave 1 were 1.70 times more likely to be died at Wave 4 than the people who did not smoke at Wave 1. Conclusions: All demographics and health behaviors at wave 1 had consistently similar OR trends for ADL status to each other except alcohol consumption. Smoking and exercise in health behaviors, and age and gender in demographics at Wave 1 were significant factors associated with ADL group separation at Wave 4.

Relationship between Alcohol Withdrawal Symptoms and Dopaminergic Gene Polymorphisms(DRD2, DAT, COMT) in Alcohol Dependence Patients (알코올 의존 환자의 금단 증상에 영향을 미치는 도파민계(DRD2, DAT, COMT) 유전자 다형성)

  • Choi, Tai Young;Kim, Ho-Nam;Han, Doug-Hyun;Min, Kyung-Jun;Lee, Young-Sik;Na, Chul
    • Korean Journal of Biological Psychiatry
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    • v.13 no.3
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    • pp.178-190
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    • 2006
  • Objectives : We investigated the relationship of the alcohol withdrawal symptoms with genetic polymorphism among alcohol dependence patients. Method : The measuring instruments used in this study were the Clinical Institute Withdrawal Assessment for Alcohol(CIWA-Ar). We analyzed DRD2 TaqI A polymorphism, dopamine transporter(DAT 1) polymorphism, and catechol-O-methyltransferase(COMT) polymorphism in 108 male alcoholics and 76 healthy controls. Results : The major findings was as follows. No significant differences for genotype distribution or allele frequency were revealed comparing controls and alcoholic patients. DRD2 Taq I : The subscale score of auditory hallucination among CIWA-Ar scale in homozygote was significantly higher than in heterozygote(OR=1.34). The total score of CIWA-Ar scale in heterozygote was significantly higher than in homozygote. DAT1 : In the subject without DAT-9 gene allele, it was significantly higher of the subscale score of sweating, anxiety among CIWA-Ar scale than in the subject with DAT-9 gene allele. And The total score of CIWA-Ar scale in the subject without DAT-9 gene allele was significantly higher than in the subject with DAT-9 gene allele. COMT : The total score of CIWA-Ar scale in heterozygote was significantly higher than in homozygote. Conclusion : Our results suggest the relationship between specific genetic factors and the withdrawal symptoms of alcohol dependent patients. As the candidate gene of the severity of alcohol withdrawal syndrome, DRD2 Taq1 gene was recommended.

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Measurement of Polymer Chain Depletion Layer in the Poly(vinyl alcohol)/Dimethyl Sulfoxide/Polystyrene Latex System by Dynamic Light Scattering (동적 광산란법에 의한 폴리(비닐 알코올)/디메틸설폭사이드/폴리스티렌 라텍스 계에서의 고분자 사슬 배제층 측정)

  • Eom, Hyo-Sang;Park, Il-Hyun
    • Polymer(Korea)
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    • v.36 no.5
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    • pp.628-636
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    • 2012
  • The polymer concentration dependence of depletion layer was investigated by means of dynamic light scattering after the very small amount of polystyrene spherical latex particles was added into the matrix solution of poly(vinyl alcohol)(PVA)/dimethyl sulfoxide. At the dilute regime, the magnitude of depletion layer kept constant at the level of $63{\pm}3%$ of the radius of gyration of the corresponding PVA chain. Next, at the early semi-dilute regime of $1.5{\leq}C[{\eta}]{\leq}3$, polymer concentration dependence of the layer thickness ${\delta}$ was obtained as ${\delta}{\sim}C^{-0.8}$, and this experimental value was very close to theoretical one of -0.75. However it was observed above $C[{\eta}]$ >3 that its thickness decreased abruptly, and this was ascribed to aggregation effect of latex particles which was driven by Oosawa type attractive interaction.

Relationship among Dysfunctional Attitudes, Stress Coping Strategies and Depressive Symptoms in Psychiatric Patients (정신질환자들의 역기능적 태도, 스트레스 대처 방식 및 우울증상 간의 관계)

  • Park, Chan-Moo;Seo, Kyung-Ran;Rhee, Min-Kyu
    • Korean Journal of Psychosomatic Medicine
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    • v.5 no.1
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    • pp.31-42
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    • 1997
  • This study was aimed to investigate dysfunctional attitudes, stress coping strategies and depressive symptoms in psychiatric patients. The subjects of this study consisted of 210 patients(138 schizophrenic patients, 29 depression patients, 43 alcohol dependence patients) according to DSM-IV criteria. Futhermore, the instruments were K-BDI(Beck Depression Inventory-Korean version), DAS(Dysfunctional Attitude Scale) and multidimensional coping strategy scale. The results were the following. 1) There were statistically significant correlations between depressive symptoms and dysfunctional attitudes in psychiatric patients. 2) In terms of coping strategies, there were positive correlations between depressive symptoms and focus on and venting emotions, accommodation, active forgetting, self-criticism, positive comparison, fatalism, passive withdrawal. Whereas, there was significant negative correlation between depressive symptom and active coping. 3) In terms of coping strategies, there were significant correlations between dysfunctional attitudes and focus on and venting emotions, active forgetting, self-criticism, positive comparison, fatalism, passive withdrawal. 4) Depression groups reported significantly higher BDI scores than schizophrenia groups. 5) In depression groups, DAS scores were significantly higher than those in schizophrenia groups. 6) In terms of coping strategies according to diagnosis, there were significant differences in venting emotions, active forgetting and self-criticism. As for venting emotions, alcoholic groups were scored significantly higher than schizophrenic groups. As for active forgetting, depression groups were scored significantly higher than schizophrenic groups. In self-criticism, depression groups and alcohol dependence groups reported significantly higher scores than schizophrenic groups.

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Anxiety, Impulsiveness, and Drinking Problems in Employed Women (직장 여성의 불안, 충동성과 음주문제)

  • Lee, Hyun Jae;Han, Doug Hyun;Lee, Young Sik;Kee, Baik Seok;Kwon, Hye Jin;Park, Doo Byung
    • Anxiety and mood
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    • v.7 no.2
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    • pp.73-78
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    • 2011
  • Objectives : This study examined drinking habits, anxiety, and impulsiveness in employed women. Methods : We sampled 925 residents aged over 20 years in Gwanak-gu of Seoul. In the process, we divided subjects into employed women and unemployed women groups and then used the Korean Version of Alcohol Use Disorder Identification Test (AUDIT-K), State-Trait Anxiety Inventory (STAI), and Barratt Impulsiveness Scale (BIS) to identify patterns in subjects' alcohol drinking, anxiety and impulsiveness. Results : Among the 925 respondents, 95.7% drank alcohol, and after the analysis, female problematic drinking ($12{\leq}AUDIT-K{\leq}25$) and alcohol dependence ($AUDIT-K{\geq}26$) was apparent in 61 (9.5%) and 2 respondents (0.3%), respectively. Female respondents who had jobs tended to drink more and exhibit higher ratios of problematic drinking, with a higher exposure to alcohol than those that were unemployed. The psychological attributes related to female respondents' alcohol problems related to state of anxiety and impulsiveness. Employed women respondents also showed a higher state of anxiety and impulsiveness than unemployed women. Conclusion : Controlling the frequency of exposure to alcohol, anxiety, and impulsiveness in employed women should be considered to be crucial controlling factors related to the hazards of excessive drinking.

Clinical and Neuropsychological Characteristics of Adult Alcohol Use Disorder Patients with or without Attention-Deficit Hyperactivity Symptom (성인 알코올사용장애 환자에서 주의력결핍 과잉행동 증상 유무에 따른 임상적 및 신경심리학적 특성)

  • Jo, Jung Min;Lee, Dong Jun;Jung, Kyung Hi;Oh, Song In;Ahn, Dong Hyun
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.25 no.4
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    • pp.209-216
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    • 2014
  • Objectives : Alcohol use disorder (AUD) is often comorbid with adult attention-deficit hyperactivity disorder (ADHD) and other psychiatric illnesses. When associated with other mental problems, the prognosis of the AUD can be more serious. This study shows research on the clinical and neuropsychological characteristics according to whether or not ADHD symptoms and AUD were comorbid. Methods : A total of 64 adult inpatients who completed AUD scales about adult ADHD, alcohol dependence, depression, anxiety, and impulsiveness. They also completed neuropsychological tests about attention and executive function. According to the Adult ADHD Self-Report Scale score, patients were categorized into two groups (ADHD symptom positive/negative group). Results : Fourteen among the 64 subjects were part of the ADHD symptom positive group (21.9%). They had statistically significant shorter abstinence periods and a higher rate of history of 'rule violation during school' and 'physical damage in childhood' compared to the ADHD symptom negative group. Conclusion : The comorbidity rate with ADHD symptom in adult AUD is higher than the general population. The ADHD symptom positive group suffered from more severe and refractory AUD. Considering the more frequent history of rule violation during school in the ADHD symptom positive group, the association between ADHD and AUD may be mediated by conduct disorder. Therefore we suggest the necessity of careful evaluation and intervention in children and adolescents with ADHD and conduct disorder.

A Study on Alcoholics Living like a Family in the Jokbang Village: Focusing on 'Relationship' and 'Emotional Bond' (가족처럼 살아가는 쪽방촌 알코올 의존자들의 일상 탐구: '관계'와 '유대감'을 중심으로)

  • Choi, Mi Kyung;Sang, Chong Ryel
    • Journal of Convergence for Information Technology
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    • v.9 no.5
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    • pp.235-242
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    • 2019
  • we explored the case of 'H-Community', a private organization that supports alcohol-dependent homeless people living in the Jokbang village, based on the awareness that "the key to social assistance for alcohol-dependent homeless may be an influential relationship to replace the role of their families." The data collection and analysis followed the research that Spradley presented, and the result was 'living in the balance rather than the great affection'. However, the density of the relationship and emotional bond appeared different, which had something to do with their respective life processes and their health, age and economic conditions. These differences were categorized and suggested as arguments through 'a family-alternative relationship', 'emotional bond' and 'participation'. Based on the results, the conclusions presented the implications needed for alcohol-dependent homeless people.

Relationship between Problematic Drinking Behavior and the Personalities of High School Students (고등학생의 음주문제행동과 성격특성)

  • Cho, Won-Jung;Kim, Gwang-Suk;Seo, Ku-Min;Kwon, In-Sook
    • Research in Community and Public Health Nursing
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    • v.15 no.3
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    • pp.471-482
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    • 2004
  • Purpose: This study intended to identify personality factors and related problematic behaviors of adolescents who drink alcohol in order to provide basic data for developing nursing programs. Methods: The data were collected from October to December 2002 from 1.080 high school students in Seoul. The Revised Cloninger's Tri-dimensional Personality Questionnaire (TPQ) was used to measure their personalities. The alcohol expectancy was measured using the tool revised by Cho (1999) and stress levels were measure using a stress tool revised Cho (1998). The data were analyzed with SPSS Windows using Chi square test. independent t-test. and logistic regression analysis. Results: 1. The percentage of fathers who drank was 79.8%. mothers. 54.3%. and friends. 54.3%. The alcohol expectancy averaged 6.36 while the stress levels were 132.79. 2. It was found that there are significant differences (p<.001) in problematic drinking behaviors according to the following variables: second year high school students among all grade variables, more monthly pocket money for the amount of money variables, the group of students who smoked in the case of the variable related to smoking, spending more time using the Internet for the Internet use variable, and having friends who drink 65.6% for the friend variable. The alcohol expectancy scale of those students who showed problematic drinking behaviors was higher than that of those who did not. There are four family-related stress subscales, and there was a significant difference among them (p<.05). Among the personal characteristics, the group who displayed problematic drinking behaviors seeks new experiences and reward dependence more than the group who did not exhibit those behaviors, and there were significant differences between the two groups (p<.001). 3. When the socio-demographic and drinking-related factors were controlled, the tendency of seeking new experiences increased the risk of problematic behaviors 1.07 times (p<.05). Compared to the non smoking group, the smoking group was found to have a 5.06 time (p<.001) greater risk of displaying problematic drinking behaviors. In comparison with the non drinking group, the drinking group was also found to have a 5.31 time (p<.001) greater risk of exhibiting problematic drinking behaviors. The group with high alcohol expectancy scores was significantly different from the group with the no alcohol expectancy, showing a 1.26 time (p<.00l) greater risk of problematic drinking behaviors. Conclusions: Based on these results, the problematic drinking behaviors were connected with alcohol expectancies, friends and personality types. Therefore, we should develop an alcoholic prevention program for adolescence considering the above results.

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A Study of the Effect of an Avatar Encouraging Drinking in Virtual Reality on Alcohol Craving (가상현실에서의 아바타 음주권유가 갈망감 유발에 미치는 영향에 관한 연구)

  • Choi, You-Kyung;Cho, Sang-Woo;Han, Ki-Wan;Ku, Jeong-Hun;Jung, Young-Chul;Kim, Jae-Jin;Kee, NamKoong;Kim, In-Yong
    • 한국HCI학회:학술대회논문집
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    • 2008.02a
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    • pp.823-828
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    • 2008
  • This study set out investigate what kind of changes would be caused to the craving of alcohol dependent patients by stimuli through virtual reality in the preparation stage for drinking refusal training. With regard to stimulation, it included alcohol exposure, a positive situation, and a negative situation on the basis of drinking encouraging situations(social pressure) known as drinking stimulating situations for alcoholics. The purpose of the study is to provide fundamental materials for the development of new training programs to refuse alcohol and for the examination of the possibility of utilizing virtual reality technology as a new treatment and training tool for alcoholics. To this end, a virtual reality program was conducted involving 12 alcoholics admitted to Severance Mental Health Hospital in Gyeonggi province from December 2006 to September 2007. The data was dealt with various statistic analyses such as frequency analysis, Wilcoxon Matched-pairs Signed-Ranks Test using SPSS/WIN 11.5 The analysis results indicate that avatars encouraging drinking caused more craving than just the background, that the scenes with alcohol exposed caused more craving than the scenes with no alcohol exposed, and that there were no significant changes to craving according to a positive or negative situation. The results confirmed that training sessions using virtual reality presented a situation and environment of drinking pressure that's similar to the actual social pressure and that the virtual reality approach had enormous potential as an effective treatment tool when combined with the existing treatment techniques.

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fMRI evidence of compensatory mechanisms during a verbal working memory task in individuals with alcohol use disorders (알코올 사용 장애자의 언어 작업 기억과 관련된 뇌의 보상 기전: fMRI 연구)

  • Park, Mi-Suk;Son, Seon-Ju;Park, Ji-Eun;Eum, Yeong-Ji;Kim, Suk-Hui;Yu, In-Gyu;Son, Jin-Hun
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 2009.05a
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    • pp.101-104
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    • 2009
  • This study investigated compensatory mechanisms in the brain during a verbal working memory task among people with Alcohol Use Disorders (AUD). A total of 21 college male students participated in the study: eleven AUD participants and 10 normal controls. Study participants were asked to complete the Korean version of the Wechsler Adult Intelligence Scale-III (K-WAIS-III) prior to the fMRI experiment. Verbal 0-back and 2-back tasks were used to assess brain activities of the participants' verbal working memory. Brain scanning was performed on Siemens SONATA 1.5T Scanner while participants were performing the 0-back and 2-back tasks. Within the AUD group, participants with greater dependency to alcohol (based on DSM-IV criteria) in the past 1 year showed lower mean score on the 'Similarities' of the K-WAIS-III (r=-0.63, p<0.05, N=11). The more participants experienced alcohol withdrawal symptoms in the past 1 year, the lower the score they received on the K-WAIS-III 'Picture Arrangement' (r=-0.69, p<0.05, n=11). The fMRI regression results showed that individuals who present greater degree of alcohol dependency symptoms are likely to show greater brain activation in the bilateral middle frontal gyri (BA 9) during the verbal working memory task. The degree of alcohol withdrawal symptoms were associated with increased brain activation in the left superior and middle frontal gyri (BA8), left precentral gyrus (BA 6), and left inferior parietal lobule (BA 40). The study findings showed that the degree of alcohol abuse/dependence and withdrawal symptoms were associated with decreased cognitive function and increased activations in brain regions particularly important for abstract reasoning (BA 9), central executive (BA 9), or spatial storage (BA 40) during a working memory task. Therefore, these results could support previous studies suggesting that the neural system of people with ADD may adopt a brain compensatory mechanism to maintain normal level of cognitive functions.

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