• Natural Product Sciences
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• v.28 no.4
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• pp.194-200
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• 2022

Albizia julibrissin Durazz. (AJ; family Minosaceae) is widely distributed worldwide, and its stem bark has been used as a traditional herbal medicine. Acute kidney injury (AKI) is a clinical syndrome that results in sudden loss of renal function. This study aimed to investigate the effects of AJ against cisplatin-induced AKI using a human kidney proximal tubule epithelial cell line (HK-2) and cisplatin-treated mice. In vitro, cisplatin treatment increased apoptosis in HK-2 cells. However, AJ treatment decreased apoptosis of cisplatin-treated HK-2 cells. In vivo, cisplatin treatment accelerated renal injury by increasing the levels of renal injury markers, such as blood urea nitrogen, creatinine, kidney injury molecule 1, and neutrophil gelatinase-associated lipocalin, which were reversed by AJ treatment. Histopathologically, AJ treatment resulted in decreased renal damage with less tubular necrosis and brush border desquamation compared with the AKI group. Additionally, cisplatin treatment upregulated mitochondrial fission, a pathological characteristic of AKI, which was downregulated by AJ treatment. Along with increased mitochondrial fission, AJ treatment also reduced cisplatin-induced apoptosis. These results suggest that AJ may be a potential therapeutic agent for cisplatin-induced AKI.

• Korean Journal of Pharmacognosy
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• v.27 no.2
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• pp.155-158
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• 1996

The methanol extract of Albizzia julibrissin Durazz. (Leguminosae) was successively partitioned into dichloromethane, ethylacetate, butanol (BuOH) and water fractions, and the effects of the each solvent extract on catecholamine biosynthesis in PC12 cells were investigated. Among them, the BuOH fraction $(5{\mu}g/ml\;medium)$ showed 68.8% and 63.6% inhibition on dopamine and norepinephrine content in PC12 cells, respectively. Tyrosine hydroxylase (TH) activity was also reduced markedly by treatment of the BuOH fraction (41.8% inhibition at $5{\mu}g/ml$ in the medium). Each solvent fraction did not show cytotoxicity towards PC12 cells by trypan blue exclusion test. This result suggests that the BuOH fraction has an inhibitory effect on catecholamine biosynthesis by reducing TH activity in PC12 cells.

• The Korean Journal of Community Living Science
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• v.26 no.4
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• pp.675-681
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• 2015

This study investigates traditional knowledge of plants used for river fishing in local communities of North Jeolla Province, Korea. Data were collected using the participatory rural appraisal method based on interviews, informal meetings, open and group discussions, and overt observations with semi-structured questionnaires. Field investigations were conducted at 19 sites from July 2008 to April 2010. Interviews included 37 key informants (16 men and 21 women) who lived more than 50 years in the area. The average age of the informants was 83 (range = 60 to 96). The analysis recorded seven species, namely Albizia julibrissin Durazz., Juglans mandshurica Maxim., Perilla frutescens var. japonica (Hassk.) H. Hara, Nelumbo nucifera Gaertn., Persicaria hydropiper (L.) Spach, Zanthoxylum piperitum (L.) DC., and Styrax japonicus Siebold and Zucc..

• Journal of agriculture & life science
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• v.51 no.1
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• pp.57-67
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• 2017

We conducted this study to investigate vegetation structure and soil conditions of six Viburnum erosum Thunb.(V. erosum) populations which showed high dominance. A total of 68 woody plants were observed to distribute: 13 in tree layer; 38 in subtree layer; and 48 in shrub layer. Based on the Mean Importance Value(MIV), the dominant tree species in the V. erosum populations were as follows in order of: Acer pseudosieboldianum(Pax) Kom., Callicarpa japonica Thunb., Indigofera kirilowii Maxim. ex Palib., Lindera obtusiloba Blume, Prunus sargentii Rehder, Quercus variabilis Blume, Rhododendron mucronulatum Turcz. and Vaccinium oldhamii Miq. In paticular, the species observed in all of the study sites were Quercus serrata Murray and Styrax japonicus Siebold & Zucc. It was found that the presence of V. erosum was positively correlated with that of Albizia julibrissin Durazz. and Symplocos chinensis f. pilosa (Nakai) Ohwi, while negatively correlated with that of Platycarya strobilacea Siebold & Zucc. According to the result, means of species diversity(H'), maxim species diversity(H' max), evenness(J') and dominance(1-J') were measured at 0.887, 1.102, 0.803, and 0.196, respectively. The soil conditions properties of pH value, organic matter content, total nitrogen content, and the amount of available phosphorous indices in the study sites were 4.3, 10.6%, 0.34% and $0.68mg{\cdot}kg^{-1}$, respectively. Meanwhile, the total amount of exchangeable cations of $Ca^{2+}$, $K^+$, and $Mg^{2+}$ were $16.84cmol_c{\cdot}kg^{-1}$, $6.41cmol_c{\cdot}kg^{-1}$, and $4.26cmol_c{\cdot}kg^{-1}$, respectively. Overall, Viburnum erosum Thunb. populations tend to grow in the strongly acid soil, which has great abundance of soil organic matters, a lot of exchangeable cations, and has higher amount available phosphorous than that of nitrogen.