Records of weight, age, body condition at calving and udder characteristics scores of 425 beef cows and birth weights and periodical weights of their offspring from birth to weaning were analyzed to study the effect of body weight, condition and udder characteristic scores of dams on birth weight and Preweaning growth of their offspring. Dam's body condition (fat reserve) at calving were scored on a scale of 1 to 5 (1=extremely thin and 5=extremely fat) and dam's udder characteristics were scored on a scale of 1 to 7 (l=udder well attached with small teats and 7=at least one quarters not functional). Dams were from three distinct breed groups and were mated in single sire mating groups within each breed group for 45 days. Within each breed group and year, the dams were classified into high, medium and low based on their weights at the time of parturition. The data were analysed using covariance analysis. In general, calves born to heavier dams were heavier at birth and had higher rate of Preweaning growth. The effect of dam's body condition score on the calf birth weight was not significant. However, cows with average body condition score of 2.5 or 3.0 gave birth to calves that had higher pre weaning growth rates up to weaning than those born to calves with higher body condition score. The udder characteristics score did not affect calf birth weight as expected; however, cows with udder score of 3 (udder well attached with large teats) produced calves with higher preweaning growth rate than those with smaller teats. Based on the results, it can be concluded that maintaining animals with average body condition and weight would result in more efficient calf production. In addition, cows with well attached udder and large teats would provide a better maternal environment for Preweaning growth rates of their calves.
Maxwell, Annette E.;Stewart, Susan L.;Glenn, Beth A.;Wong, Weng Kee;Yasui, Yutaka;Chang, L. Cindy;Taylor, Victoria M.;Nguyen, Tung T.;Chen, Moon S.;Bastani, Roshan
Asian Pacific Journal of Cancer Prevention
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v.13
no.4
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pp.1687-1692
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2012
Background: Few studies have examined theoretically informed constructs related to hepatitis B (HBV) testing, and comparisons across studies are challenging due to lack of uniformity in constructs assessed. The present analysis examined relationships among Health Behavior Framework factors across four Asian American groups to advance the development of theory-based interventions for HBV testing in at-risk populations. Methods: Data were collected from 2007-2010 as part of baseline surveys during four intervention trials promoting HBV testing among Vietnamese-, Hmong-, Korean- and Cambodian-Americans (n = 1,735). Health Behavior Framework constructs assessed included: awareness of HBV, knowledge of transmission routes, perceived susceptibility, perceived severity, doctor recommendation, stigma of HBV infection, and perceived efficacy of testing. Within each group we assessed associations between our intermediate outcome of knowledge of HBV transmission and other constructs, to assess the concurrent validity of our model and instruments. Results: While the absolute levels for Health Behavior Framework factors varied across groups, relationships between knowledge and other factors were generally consistent. This suggests similarities rather than differences with respect to posited drivers of HBV-related behavior. Discussion: Our findings indicate that Health Behavior Framework constructs are applicable to diverse ethnic groups and provide preliminary evidence for the construct validity of the Health Behavior Framework.
This study aims to describe levels and distribution of the continuity of primary care among children and adolescent patients who are 2-19 years old, and analyze the effects of it on the risk of hospitalization. Study population was 2-19 year old child and adolescent patients as of 2002, who had more than three ambulatory care visits in the years of 2002-3 and whose most frequent provider was the primary care practices (189,660 persons). Association of levels of primary care with the risk of hospitalization was evaluated using multiple event survival analysis. Outcome variables were whether the patient had hospitalized or not, and whether the patient had hospitalized due to ambulatory care-sensitive conditions or not. Multiple event survival analysis revealed statistically significant association of the levels of primary care with the risk of hospitalization. Hazard ratio was 1.34 [1.27-1.41] at the medium level of continuity and 1.47 [1.39-1.55] at the lower level where outcome variable was whether the patient had been hospitalized or not. Hazard ratios were 1.35 [1.21-1.50] at the medium level of continuity and 1.60 [1.44-1.78] at the lower level, where outcome variable was whether the patient been had hospitalized due to ambulatory care-sensitive conditions or not. This study produced some evidences on the benefits of continuity of care, which will in turn support the introduction of personal doctor registration program in the future.
This paper presents a unique study of Structural Health Monitoring (SHM) for the maintenance decision making about a real life movable bridge. The mechanical components of movable bridges are maintained on a scheduled basis. However, it is desired to have a condition-based maintenance by taking advantage of SHM. The main objective is to track the operation of a gearbox and a rack-pinion/open gear assembly, which are critical parts of bascule type movable bridges. Maintenance needs that may lead to major damage to these components needs to be identified and diagnosed timely since an early detection of faults may help avoid unexpected bridge closures or costly repairs. The fault prediction of the gearbox and rack-pinion/open gear is carried out using two types of Artificial Neural Networks (ANNs): 1) Multi-Layer Perceptron Neural Networks (MLP-NNs) and 2) Fuzzy Neural Networks (FNNs). Monitoring data is collected during regular opening and closing of the bridge as well as during artificially induced reversible damage conditions. Several statistical parameters are extracted from the time-domain vibration signals as characteristic features to be fed to the ANNs for constructing the MLP-NNs and FNNs independently. The required training and testing sets are obtained by processing the acceleration data for both damaged and undamaged condition of the aforementioned mechanical components. The performances of the developed ANNs are first evaluated using unseen test sets. Second, the selected networks are used for long-term condition evaluation of the rack-pinion/open gear of the movable bridge. It is shown that the vibration monitoring data with selected statistical parameters and particular network architectures give successful results to predict the undamaged and damaged condition of the bridge. It is also observed that the MLP-NNs performed better than the FNNs in the presented case. The successful results indicate that ANNs are promising tools for maintenance monitoring of movable bridge components and it is also shown that the ANN results can be employed in simple approach for day-to-day operation and maintenance of movable bridges.
Background: Breast cancer is one of the most common cancers in women in the world. Health-related quality of life (HRQL) at treatment endpoint in cancer clinical trials is widely considered to be increasingly important. The aim of this review was to provide a literature-based assessment of the validity, reliability and responsiveness of breast cancer-specific HRQL instruments in women breast cancer patients. Materials and Methods: The databases consulted were Medline, PubMed, and Embase. The inclusion criteria required studies to: (1) involve use of HRQL measures; (2) cover women with breast cancer under standard treatment (surgery, radiation therapy, chemotherapy, hormone therapy, and targeted therapy); (3) involve the validity, reliability, or responsiveness of HRQL; (4) deal with validation of breast cancer-specific HRQL instruments. Results: A total of 16 studies were identified through the literature search that met the 4 inclusion criteria. Some seven instruments were assessed among these 16 studies: EORTC QLQ-BR23, FACT-B, FACT-ES, HFRDIS, LSQ-32, QLICP-BR, and SLDS-BC. EORTC QLQ-BR23, FACT-B, LSQ-32, QLICP-BR, and SLDS-BC are more general breast cancer-specific HRQL instruments. FACT-EB is the endocrine subscale combined with FACT-B in order to measure the side effects and putative benefits of hormonal treatment administered in breast cancer patients. HFRDIS is the HRQL measure focusing on hot flash concerns. Conclusions: This paper provides an overall understanding on the currently available breast cancer-specific HRQL instruments in women breast cancer patients.
Young lambs (Suffolk wethers, n=18), which were 22 to 26 kg average BW, were chronically exposed to temperatures of +1 to +$4^{\circ}C$ (cold) or +21 to +$24^{\circ}C$ (warm) during 10 wk experimental periods. The sheep were closely shorn and were housed in individual metabolism crates in controlled environment rooms. Sheep consumed pelleted diets ad libitum, which consisted of mainly barley grain and brome grass, and contained 7, 11, or 14% CP. The experimental design consisted of a $2{\times}3$ factorial with a single crossover of environment treatment. Feed intake, BW, feces, and urine excretion were measured. Apparent digestibilities were not affected by diet CP concentration or temperature treatments; however, voluntary intake per kg BW was increased (p<0.05) by diet CP content in both environments. Growing lambs gained weight slightly faster in a cold environment when N intake was above 27 g/d. Nitrogen excretion and N balance were positively related (p<0.01) with diet CP content, and fecal N excretion was significantly increased (p<0.05) in the cold environment. Therefore, dietary CP content strongly influenced N metabolism; however, cold exposure did alter only fecal N excretion. The higher DM intake per kg BW at 11% CP diet in the cold environment permitted ADG comparable to 14% CP diet in the warm environment. The results of this study do support the hypothesis that lambs are better able to utilize a moderate reduction in the CP content of the diet in a cold environment.
The effect of a homolactic inoculant containing a blend of Lactobacillus plantarum, Pediococcus acidilactici and Enterococcus faecium or, the anionic surfactant, sodium dodecyl sulphate (SDS), alone or in combination on fermentation characteristics, aerobic stability and in situ DM, OM and NDF degradability of barley silage was investigated. Barley (Hordeum vulgare, L.) was harvested (45% DM), chopped and treated with water at 24 ml/kg forage (Control), inoculant at $1.09{\times}10^5$ cfu/g forage (I), SDS at 0.125% (wt/wt) of forage (S) or with the inoculant ($1.09{\times}10^5$ cfu/g) plus SDS (0.125% wt/wt; I+S). The treated forages were ensiled in triplicate mini silos and opened for chemical and microbiological analyses on d 1, 2, 3, 7, 14, 42 and 77. Silage samples from d 77 were opened and aerobically exposed for 7 d. The in situ rumen degradability characteristics of silage DM, OM and NDF were also determined. The terminal concentration of NDF in S and I+S was lower (p<0.001) than in other treatments. Lactate concentration was higher (p<0.001) and the rate and extent of pH decline were greater (p<0.001) in I and I+S than S and Control silages. A homolactic pathway of fermentation in I and I+S was evidenced by reduced (p<0.001) water-soluble carbohydrates concentration, higher lactate (p<0.01), lower acetate (p<0.01) and lower pH values (p<0.001) than in S and Control silages. All silages remained stable over 7 d of exposure to air as indicated by lower temperatures and moulds, and by non-detectable yeast populations. The treated silages had lower DM and OM degradability than in the Control but NDF degradation characteristics of I+S were improved compared to other treatments. It is concluded that the inoculant alone improved the fermentation characteristics whereas the combination of the inoculant with SDS improved both fermentation and NDF degradability of barley silage.
Objective : The objective of this study was to develop a score to predict patients with acute ischemic stroke (AIS) who will not benefit from endovascular treatment (EVT) using computed tomographic angiography (CTA) parameters. Methods : The CTA-ABC score was developed from 3 scales previously described in the literature: the Alberta Stroke Program Early CT Score (0-5 points, 3; 6-10 points, 0), the clot burden score (0-3 points, 1; 4-10 points, 0), and the leptomeningeal Collateral score (0-1 points, 2; 2-3 points, 0). We evaluated the predictive value of CTA parameters associated with symptomatic intracranial hemorrhage (sICH) or malignant middle cerebral artery infarction (MMCAI) after EVT and developed the score using logistic regression coefficients. The score was then validated. Performance of the score was tested with an area under the receiver operating characteristic curve (AUC-ROC). Results : The derivation cohort consisted of 115 and the validation cohort consisted of 40 AIS patients. The AUC-ROC was 0.97 (95% confidence interval [CI], 0.94-0.99; p<0.001) in the derivation cohort. The proportions of patients with sICH and/or MMCAI in the derivation cohort were 96%, 73%, 6%, and 0% for scores of 6, 5, 1, and 0 points, respectively. In the validation group, the proportions were similar (90%, 100%, 0%, and 0%, respectively) with an AUC-ROC of 0.96 (95% CI, 0.90-1.00; p<0.001). Conclusion : Our CTA-ABC score reliably assessed risk for sICH and/or MMCAI in patients with AIS who underwent EVT. It can support clinical decision-making, especially when the need for EVT is uncertain.
Kim, Eun T.;Guan, Le Luo;Lee, Shin J.;Lee, Sang M.;Lee, Sang S.;Lee, Il D.;Lee, Su K.;Lee, Sung S.
Asian-Australasian Journal of Animal Sciences
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v.28
no.4
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pp.530-537
/
2015
The objective of this study was to evaluate the in vitro effects of flavonoid-rich plant extracts (PE) on ruminal fermentation characteristics and methane emission by studying their effectiveness for methanogenesis in the rumen. A fistulated Holstein cow was used as a donor of rumen fluid. The PE (Punica granatum, Betula schmidtii, Ginkgo biloba, Camellia japonica, and Cudrania tricuspidata) known to have high concentrations of flavonoid were added to an in vitro fermentation incubated with rumen fluid. Total gas production and microbial growth with all PE was higher than that of the control at 24 h incubation, while the methane emission was significantly lower (p<0.05) than that of the control. The decrease in methane accumulation relative to the control was 47.6%, 39.6%, 46.7%, 47.9%, and 48.8% for Punica, Betula, Ginkgo, Camellia, and Cudrania treatments, respectively. Ciliate populations were reduced by more than 60% in flavonoid-rich PE treatments. The Fibrobacter succinogenes diversity in all added flavonoid-rich PE was shown to increase, while the Ruminoccocus albus and R. flavefaciens populations in all PE decreased as compared with the control. In particular, the F. succinogenes community with the addition of Birch extract increased to a greater extent than that of others. In conclusion, the results of this study showed that flavonoid-rich PE decreased ruminal methane emission without adversely affecting ruminal fermentation characteristics in vitro in 24 h incubation time, suggesting that the flavonoid-rich PE have potential possibility as bio-active regulator for ruminants.
Objective: The objective of this study was to determine the five-year survival among patients with cervical cancer treated in Hospital Universiti Sains Malaysia. Methods: One hundred and twenty cervical cancer patients diagnosed between $1^{st}$ July 1995 and $30^{th}$ June 2007 were identified. Data were obtained from medical records. The survival probability was determined using the Kaplan-Meier method and the log-rank test was applied to compare the survival distribution between groups. Results: The overall five-year survival was 39.7% [95%CI (Confidence Interval): 30.7, 51.3] with a median survival time of 40.8 (95%CI: 34.0, 62.0) months. The log-rank test showed that there were survival differences between the groups for the following variables: stage at diagnosis (p=0.005); and primary treatment (p=0.0242). Patients who were diagnosed at the latest stage (III-IV) were found to have the lowest survival, 18.4% (95%CI: 6.75, 50.1), compared to stage I and II where the five-year survival was 54.7% (95%CI: 38.7, 77.2) and 40.8% (95%CI: 27.7, 60.3), respectively. The five-year survival was higher in patients who received surgery [52.6% (95%CI: 37.5, 73.6)] as a primary treatment compared to the non-surgical group [33.3% (95%CI: 22.9, 48.4)]. Conclusion: The five-year survival of cervical cancer patients in this study was low. The survival of those diagnosed at an advanced stage was low compared to early stages. In addition, those who underwent surgery had higher survival than those who had no surgery for primary treatment.
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