• The Plant Pathology Journal
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• 제30권2호
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• pp.151-158
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• 2014

Three double-stranded RNAs (dsRNAs), approximately 1.85, 1.65 and 1.27 kb in size, were detected in an isolate of Cytospora sacchari from Iran. Partial nucleotide sequence revealed a 1,284 bp segment containing one ORF that potentially encodes a 405 aa protein. This protein contains conserved motifs related to RNA dependent RNA polymerases (RdRp) that showed similarity to RdRps of partitiviruses. The results indicate that these dsRNAs represent a novel Partitivirus that we tentatively designate Cytospora sacchari partitivirus (CsPV). Treatment of the fungal strain by cyclohexamide and also hyphal tip culture had no effect on removing the putative virus. Phylogenetic analysis of putative RdRp of CsPV and other partitiviruses places CsPV as a member of the genus Partitivirus in the family Partitiviridae, and clustering with Aspergillus ochraceous virus 1.

• Parasites, Hosts and Diseases
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• 제46권4호
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• pp.229-234
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• 2008

The prevalence of Sarcocystis spp. was investigated by gross and histopathological examinations in 250 camels (Camelus dromedarius) slaughtered from 2002 to 2005 in the Mashhad Slaughterhouse, eastern Iran. Samples were taken from the diaphragm, heart, tongue, esophagus and masseter muscles for histopathological studies. No macroscopic sarcocysts were found in the samples at gross inspection. Sarcocysts were detected in 209 of 250 (83.6%) examined camels at histopathological level. The infection rate of the esophagus, heart, masseter muscles, diaphragm, and tongue was 58.8%, 48.0%, 46.8%, 41.6%, and 28.0%, respectively. There was no significant difference in the rate of infection between male (85.8%) and female (81.0%) camels. The tissue response to vital cysts was minimal; however, reaction to the degenerating cysts was severe and caused tissue damages resulting in hyperemia, hemorrhages, mononuclear cell infiltration, necrotic changes, and fibrosis. The wild and domestic carnivores especially dogs may be the final hosts of Sarcocystis spp. in this area.

• 한국자동차공학회논문집
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• 제15권4호
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• pp.132-138
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• 2007

Experimental results of pulsating pressure behavior inside a chamber have been confirmed by computational work. Inside-cylinder pressure shows unstable condition at low rpm. This is caused by plate-type suction valve. It has effect up to inlet of the chamber. But trembling phenomenon is reduced as the pressure is enlarged by increasing the rpm. Result comparison between experimental and numerical analysis shows pulsation reduction is affected by the chamber. We can confirm that compressible effect of the working flow is shown at chamber inlet by increasing rpm. On the other side, this effect is declined at chamber outlet by increasing rpm. It means outlet pressure is going on balance with atmosphere pressure. Buffer plate-type chamber has efficiency of pulsation flow reduction.

• Geomechanics and Engineering
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• 제10권2호
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• pp.125-135
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• 2016

Adhesion in geotechnical engineering is the interaction between cohesive soil and a solid surface which can cause clogging in mechanized tunnelling through clayey formations. Normal piston pull out and modified direct shear tests were performed on clayey soil samples to determine which type of adhesion stress, normal or tangential, could be most effectively measured. Measured values for normal adhesion ranged from 0.9 to 18 kPa. The range of tangential adhesion was 2.4 to 10 kPa. The results indicate normal adhesion results were more accurate than those for the modified direct shear test that measure tangential adhesion. Direct shear test on identical samples did not show any correlation between measured cohesion and normal adhesion values. Normal adhesion values have shown significantly meaningful variation with consistency index and so are compatible with the base of field clogging assessment criteria. But tangential adhesion and cohesion were not compatible with these assessment criteria.

• 동력기계공학회지
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• 제12권1호
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• pp.20-27
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• 2008

수소 추출과 리포밍 과정, 연료 전지, 저장소로 구성된 수소 연료에 대한 연구는 세계적으로 번영하고 있는 중이다. 그러나 한국의 수소 스테이션에 대한 연구는 아직도 개발이 미미한 수준이다. 그리고 역시 수소 스테이션의 가장 중요한 부분인 수소 압축기에 대한 연구도 미흡하다. 수소압축기에서 가장 중요한 부분 중에 하나는 스너버인데 이것의 기능은 수소가스의 맥동압을 줄이고 불순물을 제거한다. 스너버 내부에는 버퍼라고 불리는 기울어진 판이 설치되어 맥동압을 줄이고 불순물을 제거하는 역할을 담당한다. 스너버 내부의 압력 손실과 맥동압이 최소가 될 때 스너버는 적절한 성능을 가졌다고 평가된다. 그러므로 이 연구의 목적은 수치해석을 통하여 스너버의 최적의 기하학적 크기와 버퍼의 각도에 따른 최적의 스너버를 찾는 것이다. 수치해석의 결과에서 다양한 버퍼각도에 따른 스너버의 독특한 특성을 볼 수 있다. 결과적으로 버퍼의 각도가 $35^{\circ}$일때 최소의 압력손실율이 발생했고, 버퍼의 각도가 $10^{\circ}$일 때 최소의 맥동압이 발생하였다.

• 동력기계공학회지
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• 제11권1호
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• pp.76-81
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• 2007

The objective of this study is to find the optimum design of a snubber using CFD analysis. Several dimensions such as snubber height(H), snubber diameter(D), buffer width and buffer angle are considered in this study. The present study shows that the CFD can be applied to study the pressure characteristics inside the snubber. The objective of the snubber design optimization are to minimize a pressure loss and the pulsation ratio. Numerical results such as particle track, pressure distribution and turbulent kinetic energy are used to analyze the critical area and pressure behavior inside the snubber. As a result, snubber model with H/D ratio of 3.23 and buffer angle of $40^{\circ}$ has a minimum pressure loss. On the other hand, snubber model with H/D ratio 4.41 and buffer angle $10^{\circ}$ has a minimum pulsation ratio.

• Bulletin of the Korean Chemical Society
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• 제32권3호
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• pp.947-955
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• 2011

The complexes [Pd(bpy)(Hex-dtc)]$NO_3$ and [Pt(bpy)(Hex-dtc)]$NO_3$ (bpy is 2,2'-bipyridine and Hex-dtc is hexyldithiocarbamato ligands) were synthesized and characterized by elemental analysis and spectroscopic studies. The cytotoxicity assay of the complexes has been performed on chronic myelogenous leukemia cell line, K562, at micromolar concentration. Both complexes showed cytotoxic activity far better than that of cisplatin under the same experimental conditions. The binding parameters of the complexes with calf thymus DNA (CT-DNA) was investigated using UV-visible and fluorescence techniques. They show the ability of cooperatively intercalating in CT-DNA. Gel filtration studies demonstrated that platinum complex could cleave the DNA. In the interaction studies between the Pd(II) and Pt(II) complexes with CT-DNA, several binding and thermodynamic parameters have been determined, which may provide deeper insights into the mechanism of action of these types of complexes with nucleic acids.

• Structural Engineering and Mechanics
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• 제56권5호
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• pp.871-897
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• 2015

This paper presents a novel method based on sensitivity of structural response for identifying both the system parameters and input excitation force of a bridge. This method, referred to as "Adjoint Variable Method", is a sensitivity-based finite element model updating method. The computational cost of sensitivity analyses is the main concern associated with damage detection by these methods. The main advantage of proposed method is inclusion of an analytical method to augment the accuracy and speed of the solution. The reliable performance of the method to precisely indentify the location and intensity of all types of predetermined single, multiple and random damages over the whole domain of moving vehicle speed is shown. A comparison study is also carried out to demonstrate the relative effectiveness and upgraded performance of the proposed method in comparison to the similar ordinary sensitivity analysis methods. Moreover, various sources of error including the effects of noise and primary errors on the numerical stability of the proposed method are discussed.

• Bulletin of the Korean Chemical Society
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• 제30권11호
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• pp.2523-2531
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• 2009

Effects of some diacid, diamine and dinitro aromatic compounds on the structure and activity of adenosine deaminase (ADA) were investigated by UV-Vis spectrophotometry in 50 mM phosphate buffer at pH = 7.5 and 27 ${^{\circ}C}$ and molecular docking studies. The results showed that all tested ligands are showing inhibition; five ligands are uncompetitive and other two ligands are mixed of competitive and noncompetetive inhibitors with majority of competitive behavior. For the later case analysis was done based on competitive inhibition. Diacids have larger size and higher inhibition constant ($K_I$) relative to others. A logical correlation between calculated free energy of binding and experimental values was obtained for un-competitive. Experimental and calculated data showed that competitive inhibitors are distributed near the active site of enzyme and form several cluster of ranks, whereas uncompetitive inhibitors bind to the enzyme-substrate complex and distributed far from the active site. Results of structure-activity relationship showed that, larger, more hydrophobe, less spherical and more aromatic ligands have higher inhibition constants.

• Structural Engineering and Mechanics
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• 제54권6호
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• pp.1217-1244
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• 2015

In this research a theoretical and numerical study on a bridge damage detection procedure is presented based on vibration measurements collected from a set of accelerometers. This method, referred to as "Adjoint Variable Method", is a sensitivity-based finite element model updating method. The approach relies on minimizing a penalty function, which usually consists of the errors between the measured quantities and the corresponding predictions attained from the model. Moving mass is an interactive model and includes inertia effects between the model and mass. This interactive model is a time varying system and the proposed method is capable of detecting damage in this variable system. Robustness of the proposed method is illustrated by correct detection of the location and extension of predetermined single, multiple and random damages in all ranges of speed and mass ratio of moving vehicle. A comparative study on common sensitivity and the proposed method confirms its efficiency and performance improvement in sensitivity-based damage detection methods. In addition various possible sources of error, including the effects of measurement noise and initial assumption error in stability of method are also discussed.