• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1305-1310
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• 2012

Breast cancer cells undergo transformation when they spread into surrounding tissues. Studies have shown that cancer cells undergo surface alterations and interact with the surrounding microenvironment during the invasion process. The aim of the present study was to analyse these cancer cell surface alterations and interactions of cancer cells and stroma. Twenty 1-methyl-1-nitrosourea-induced breast cancer samples taken from five rats were fixed in McDowell-Trump fixative and then washed in 0.1 M phosphate buffer. The samples were then treated with osmium tetroxide before being washed in distilled water and subsequently dehydrated through graded ethanols. The dehydrated samples were immersed in hexamethyldisilazane (HMDS), then following removal of excess HMDS, the samples were air dried at room temperature in a dessicator. The dried samples were mounted onto specimen stubs and coated with gold coater before being viewed under a scanning electron microscope. We detected the presence of membrane ruffles on the surface of cancer cells and the formation of unique surface membrane protrusions to enhance movement and adhesion to the surrounding stroma during the process of invasion. Advancing cancer cells demonstrated formation of lamellipodia and invadopodia. The stroma at the advancing edge was desmoplastic with many collagen fibres laid down near the cancer cells. Our data suggest that all of these abnormalities could act as hallmarks of invasiveness for breast cancer.

• 접착 및 계면
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• 제14권4호
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• pp.183-191
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• 2013

알갱이 군에 형성되는 무더기 현상을 이해하기 위하여, 좁쌀, 모래, 은박 원판 등의 알갱이 군에 대하여 수직진동 및 회전진동을 적용하여 이들의 움직임을 조사하였다. 수직진동의 경우, Gerner의 연구처럼 무더기가 형성되었으나, 알갱이 무게와 관계없이 좁쌀, 모래, 은박원판의 무더기가 순으로 형성되었고, 은박원판의 무더기는 좁쌀과 모래에 비해 훨씬 복잡하게 나타났다. 또 회전진동의 경우, 알갱이는 용기 벽과 중력 및 알갱이 끼리 탄성 밀리기에 의해 중앙부위가 위로 솟아오르는 현상이 나타났으며, 회전진동 진폭이 큰 경우엔 나선형 문양이 나타나기도 했다. 이는 알갱이 군에 원심력, 알갱이 간 인력 및 세차운동 등이 가해지면, 무더기 현상이 지연되거나 더 난잡해짐을 의미한다. 이러한 사실로부터 화공재료 등의 알갱이의 무더기 현상은 용기의 진동 특성뿐 아니라 알갱이 간 인력의 유무에 따라서도 결정됨을 알 수 있다.

• 한국토양환경학회지
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• 제1권2호
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• pp.83-90
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• 1996

토양내에서의 가스나 증기상의 오염물질의 이동은 여러 가지 현상에 의해서 일어나고 있으나 농도차에 의해서 일어나는 확산이 가장 중요하다. 그런데 토양내에서의 확산은 토양 입자들로 인한 확산 부피의 감소, 또 확산경로의 불규칙성, 확산 경로에 있어서 단면적의 변화 등으로 인해 대기중에서 일어나는 확산과는 다른 면을 보인다. 본 논문에서는 이러한 현상을 설명하기 위하여 흔히 사용되는 굴절계수(toruosity), 유효확산계수(effective diffusion coefficient)의 서로 다른 그러나 같은 이름으로 사용되는 많은 정의들과 다양한 수학적 모델들에 대한 비교 검토가 이루어졌다. 굴절계수나 유효확산계수를 사용할 때는 각각의 경우 정의와 각 식의 특징에 대하여 세밀한 검토와 주의가 행하여져야 한다.

• 한국세라믹학회지
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• 제35권2호
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• pp.172-179
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• 1998

Valve lifter namely tappet is supported by lifter hole which is located upper side of camshaft in cylinder block transforms rotatic mvement of camshaft into linear movement and helps to open and shut the en-gine valve as an engine parts. The face of valve lifter which is continuously contacting with camshaft brings about abnormal wears such as unfair wear and early wear because it is severely loaded in the valve train system. These wears act as a defect like over-clearance and cause imperfect combustion of fuel during the valve lifting in the combustion chamber. Consequently this imperfect combustion makes the engine out-put decrease and has cause on air pollution. To prevent these wears therefore The valve lifter cast in me-tal developed into SiC ceramics valve lifter which has an excellence in wear and impact resistance As a results the optimum process conditions like injection condition mixture ratio and debonding process could be established. After sintering fine-sinered dual microstructure in which prior ${\alpha}$-SiC matches well with new SiC(${\beta}$-SiC) produced by reaction among the ${\alpha}$-SiC carbon and silicon was obtained. Based on the study it is verified that mechanical properties of SiC valve lifter are excellent in Vickers hardness 1100-1200 bending strength (300-350 Pa) fracture toughness(1.5-1.7 Mpa$.$m1/2) Through engine dynamo test-ing SiC valve lifter and metal valve lifter are examined and compared into abnormal phenomena such as early fracture unfair and early wear. It is hoped that this research will serve as an important springboard for the future study of heavy duty diesel engine parts developed by ceramics which has a good wear resis-tance relaibility and lightability.

• Architectural research
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• 제15권2호
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• pp.59-68
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• 2013

To ameliorate a long-standing, persistent housing shortage in Korea, large-scale massive housing production has been an imperative, and the extensive growth highly values development and consumption. The state's priority for the quantitative growth of housing stock has proved to be successful, but the state faces with economic and environmental crises in a global era. To achieve the qualitative growth, the previous administration pronounced a green growth policy from the inception, and a series of strategic measures under a holistic plan have been taken widely and vigorously. As part of the strategies, the green home project was undertaken, and simultaneously the movement of green living led by the governance has been activated. However, little attention to the grassroots effort was paid and the efficacy hasn't been adequately addressed. This study examines the factors affecting green living of residents in multifamily housing. Based on public guidelines to green living, 106 specific items were drawn out and largely categorized into 6 areas (water, waste, transportation, air quality, consumption, and energy), and the questionnaire was constructed using them. Of 750 survey forms mailed out, 161 responses were returned and the collected data were used for statistical analysis. The findings indicated that varying degrees of green living was well practiced, the state-led green home project was relatively well recognized, and the green growth policy was strongly supported. Also the respondents' attitude toward green living were more associated with demographic variables than housing characteristics, and familiarity with green home project was related to attitudes toward green living. Since the on-going approach to green living has focused on simple and economical ways, it has proved to be effective but progressive strategies to make living greener are necessarily developed.

• Asian Journal of Atmospheric Environment
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• 제12권1호
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• pp.17-29
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• 2018

For the first time in the city of Riyadh, the formation of $O_3$ and its relationship with NO and $NO_2$ ($NO_x$) was investigated. Throughout the summer $O_3$, NO, and $NO_2$ were collected from three locations: residential, industrial, and rural areas. During the sampling period $O_3$ concentrations exceeded 1-hour local standards a few times yet remained consistent with the standards most of the time. The $O_3$ concentrations were observed highest in the rural location and lowest in the industrial area. The diurnal variation of NO followed a double peak: one in the morning and the other in the evening, representing the traffic pattern. Early morning NO peaks were observed in the rural location, which were attributed to the movement of NO from other locations. The $O_3$ concentrations depicted typical pattern, increasing after sunrise and reaching its maximum during midday. The highest $O_3$ concentrations were observed in the rural location followed by the residential and industrial. $NO_2$ photolysis rates were 3-4 times higher compared to other similar investigations, potentially due to intense solar radiation. A strong negative correlation was observed between $NO_x$ and $O_3$ values in the industrial location indicating photochemical activities around the industrial area were higher, likely due to additional $NO_x$ emissions from industries. Regression analysis of $NO_x$ and OX ($O_3+NO_2$) indicated that in residential and industrial locations at nighttime there were large $NO_x$ independent regional contributions which is attributed to VOCs. The Weekend Effect was observed in the city potentially due to the production of the OH radical and subsequent reactions with VOCs implying that the area is VOC-sensitive.

• 대한간호학회지
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• 제29권6호
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• pp.1304-1313
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• 1999

Breathing is essential for life and at the same time takes a role as a antidote for stress. In the Orient, it was recognized early that respiration, mind, and body have a relation that is inseparable and therefore proper breathing is so important. However, since the mechanism of therapeutic effect by breathing have not been verified, the treatment has been continued till recent years. From that which originated in the Orient, several techniques in the west have been developed to regulate breathing, and have been applying to the clinical situation and to studies, however scientific studies are still lacking. Recently, relaxed breathing has been used as an efficient strategy for breathing therapy as it has an effect on reducing physiological tension and arousal, and, therefore can be used as a basic technique to control or manage stress. In this study, in order to provide basic information and guidelines for clinical application, which will aid in the application of the theoretical basics of breathing therapy and its technique, a review of the literative was conducted. The findings are as follows: 1. Since proper breathing not only has, physically, the important function in supplying oxygen to the body but also gives a good emotional, or pleasant state of mind, it is the first step in controlling physical and mental health. 2. The basic types of breathing can be classified into two types; ‘diaphragmatic breathing(relaxed breathing)’ and ‘chest breathing(stress breathing)’. In yoga type breathing, there are four kinds of breathing, ‘upper breathing’, ‘mid breathing’, ‘down breathing’, and ‘complete breathing’. 3. The theoretical explanation of the positive thera peutic effect of breathing therapy techniques exemplifies good brain function, sufficient air flow through the nasal passages, diaphragmatic movement, light vagal stimulation, CO2 changes and cognitive diversion but in most studies, the hypothesis of CO2 is supported. 4. The technique of breathing is designated with many names according to the muscles and techniques used for breathing, and for control of stress, diaphragmatic breathing(relaxed breathing) is explained as a basic technique best used to manage of stress. 5. The relaxed-breathing includes slow diaphragmatic breathing, breath meditation, nasal breathing, yogic abdominal breathing, Benson's relaxed response, and quiet response.

• 한국콘텐츠학회논문지
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• 제12권2호
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• pp.10-18
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• 2012

감시 카메라를 이용하여 화재 연기를 자동 검출하는 시스템은 신뢰도 높은 연기 영상의 검출 방법을 필요로 한다. 카메라를 이용하여 공기 중에 확산하는 연기의 영상을 연속적으로 획득하였을 때, 연기 영상의 각 장면은 독특한 텍스처(정적 텍스처)를 가지며, 연기의 확산 운동으로 인하여 그 차분 영상 또한 다른 물체와 구별이 되는 독특한 텍스처(동적 텍스처)를 가진다. 특정 객체가 연기와 유사한 정적 텍스처를 가지고 있을 지라도 그 움직임의 특성이 연기 특유의 확산 운동과 다르다면, 그 차분 영상의 텍스처는 연기의 차분 영상 텍스처와 유사할 수 없다. 본 논문에서는 이 두 가지 정적 및 동적 텍스처를 이용하여 신뢰도 높은 연기 영상 검출 방법을 제안한다. 제안하는 방법은 누적된 장면 차분 영상을 이용하여 변화 영역을 일차적으로 검출하고, 검출된 변화 영역의 정적 및 동적 텍스처로부터 추출한 Haralick 특징 벡터 이용하여 최종적으로 연기로 인한 변화 영역을 검출한다.

• 대한지리학회지
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• 제42권1호
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• pp.1-14
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• 2007

본 연구에서는 우리나라 육상 국지 예보 구역을 대상으로 예보 정확도를 분석하였다. 연구 기간 동안 평가 요소별 정확도는 강수 유무가 가장 낮았고 하늘 상태가 가장 높았다. 지역적으로 예보 정확도는 강원도에서 가장 낮았으며 경상남도와 경상북도에서 높았다. 계절별 예보 정확도의 만점 빈도는 겨울에 가장 높았고 여름에 가장 낮았다. 예보 정확도가 낮은 날의 기압 배치형을 분석했을 때 여름철에는 정체전선형 기압 배치에서 강수 유무의 예보 정확도가 낮았다. 가을과 겨울에는 한대 고기압 확장형 기압 배치에서 기온 예보의 정확도가 크게 낮아지는 경우가 많았다. 봄과 가을의 이동성 고기압형 기압 배치에서는 날씨가 급격하게 변하여 예보 정확도가 낮았다. 예보 정확도가 가장 낮은 지역인 영동 지역의 상층 850hPa 고도의 풍향 자료와 예보 정확도를 비교하여 분석한 결과, 최저 및 최고 기온은 서풍일 때, 강수 유무의 경우 동풍일 때 예보 정확도가 낮았다.

• 문화기술의 융합
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• 제6권2호
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• pp.529-534
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• 2020

인류 문명의 발전은 산업화에 따른 도시의 발전과 운송 기술의 진화와 맥을 같이한다. 지금까지의 도시 발전은 수송비 절감과 한정된 중심업무 지구로서의 토지 이용 요구에 따라 진행되어왔다. 도시 인구 밀집도의 지속적인 증가는 지가상승, 교통 혼잡, 빈부격차, 공해발생 등과 같이 사회·경제적으로 많은 문제를 일으켜 왔고 현재의 도시 생태 시스템으로는 전반적인 해결에 어려움이 있다. 그러나 문제의 해결을 위한 실마리는 바로 도시생태계 내에서 찾을 수 있다. 서울 심야버스 운행 노선의 설계는 바로 심야의 도시 내 이동 인구의 흐름을 정보통신 기술을 이용해 분석하여 얻은 결과이다. 이렇듯 도시 문제의 해결은 도시 생태계의 분석에서 출발하는 것이 타당하다. 문제의 원인을 알았다면 시민의 삶의 질을 높이기 위해 빅데이터 플랫폼 구축이 필요하고 이를 통한 해결이 가능하다. 이 플랫폼의 중심에는 정보통신 기술의 기반 하에 도시의 구성 요소와 연결되어 실시간 수집, 분석 및 적용되는 빅데이터가 자리 잡고 있어야한다. 본 연구를 통해 지속 가능한 스마트 시티를 위한 빅데이터 플랫폼 구축과 적용 방안에 대하여 고찰한다.