• 한국연초학회지
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• 제33권1호
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• pp.21-27
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• 2011

Amadori compounds(1-deoxy-1-amino-2-ketoses) are important precursors of color, flavor and aroma produced in foods. Amadori compounds occur naturally in tobacco. The contribution of amadori compounds to smoke quality has been (of) interest because of their roles of the Maillard reaction in the leaf chemistry. The amounts of these compound in tobacco are affected by the processes of aging, drying and storage conditions. In this study, eight compounds were chemically synthesized because amadori compounds (have not been sold commercially these days.) were not available for obtaining commercially. The aim of this study was to develop the analytical method of amadori compounds in tobacco leaf by the liquid chromatography mass spectrometry using triple quadrupole analyzer(LC-MS/MS). This method was simple, rapid, selective and sensitive, and eight amadori compounds were simultaneously and quantitatively analyzed within 20 minutes. This method showed excellent accuracy and precision. Recovery rates of amadori compounds ranged from 86% to 102%, with relative standard deviation(RSD) ranged from 2.6% to 5.9%. This method was applied to analysis of amadori compounds contents of tobacco leaves in different varieties. Furthermore, it was expected that the method could be extended to the analysis of other amadori compounds.

• Composites Research
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• 제12권4호
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• pp.62-70
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• 1999

건축 구조물의 재령이 증가함에 따른 손상은 구조물의 안전성 및 신뢰성 확보에 매우 심각한 문제이다. 최근에는 이렇게 손상을 입은 콘크리트 구조물의 보수 보강을 위해 탄소섬유시트가 광범위하게 사용되고 있지만 탄소섬유시트를 보강한 콘크리트의 파괴기구가 명확하게 규명되지 않았다. 따라서 본 연구에서는 탄소섬유시트를 보강한 콘크리트의 손상거동 및 미시적 파손기구를 이해하기 위해 4가지 경우의 시험편, 즉 순수한 콘크리트, 철근 보강 콘크리트, 탄소섬유시트 보강 콘크리트, 철근과 탄소섬유시트 보강 콘크리트 시험편에 대하여 3점 굽힘 시험을 실시하였다. 이러한 시험편들의 파손기구를 명확히 하기 위해 음향방출기법이 사용되었으며 균열 발생, 성장을 모니터링하기 위해 2차원 AE 발생원 위치추정 기법이 적용되었다.

• 한국분말재료학회지
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• 제16권4호
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• pp.254-261
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• 2009

In this study, we investigated the unit process parameters in spherical $UO_2$ kernel preparation. Nearly perfect spherical $UO_3$ microspheres were obtained from the 0.6M of U-concentration in the broth solution, and the microstructure of the $UO_2$ kernel appeared the good results in the calcining, reducing, and sintering processes. For good sphericity, high density, suitable microstructure, and no-crack final $UO_2$ microspheres, the temperature control range in calcination process was $300{\sim}450^{\circ}C$, and the microstructure, the pore structure, and the density of $UO_2$ kernel could be controlled in this temperature range. Also, the concentration changes of the ageing solution in aging step were not effective factor in the gelation of the liquid droplets, but the temperature change of the ageing solution was very sensitive for the final ADU gel particles.

• 한국가구학회지
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• 제28권1호
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• pp.16-26
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• 2017

In today's aging society, stable residential environment is essential for the elderly living alone to be able to do activities of daily living without restrictions and cherish a satisfactory quality of life. We developed a safe and convenient multifunctional sofa by removing complex combinations and decomposing processes of the multifunctional transformable furniture, appropriate for the use by elderly living alone. We deduced the 4 main keywords and details related to the purpose of sofa by analyzing the users' physical and mental characteristics through literature review and by using 24-hour scheduling, interviews, and actual measurement. Finally, by applying this to furniture planning, we designed 4 different types of multifunctional sofa system. Production was done in cooperation with AND Co. for 2 weeks using materials, colors and adhesives selectively chosen with careful consideration of their effects on the physical, mental aspects of the user to give optimal comfortability.

• Reproductive and Developmental Biology
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• 제39권2호
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• pp.43-47
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• 2015

Sirtuin proteins are evolutionary conserved Sir2-related $NAD^+$-dependent deacetylases and regulate many of cellular processes such as metabolism, inflammation, transcription, and aging. Sirtuin contains activity of either ADP-ribosyltransferase or deacetyltranfease and their activity is dependent on the localization in cells. However, the expression pattern of Sirtuins has not been well studied. To examine the expression levels of Sirtuins, RT-PCR was performed using total RNAs from various tissues including liver, small intestine, heart, brain, kidney, lung, spleen, stomach, uterus, ovary, and testis. Sirtuins were highly expressed in most of tissues including the testis. Immunostaining assay showed that Sirt1 and Sirt6 were mainly located in the nucleus of germ cells, spermatocytes, and spermatids in the seminiferous tubules, whereas Sirt2 and Sirt5 were exclusively present in the cytoplasm of germ cells and spermatocytes. Our results indicate that Sirtuins may function as regulators of spermatogenesis and their activities might be dependent on their location in the seminiferous tubules.

• 한국도서관정보학회지
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• 제47권3호
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• pp.241-259
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• 2016

이 연구는 학교도서관에서 이루어지고 있는 장서개발 과정을 조사하여 그 문제점을 분석하고 개선방안을 제안하고자 한 조사연구이다. 장서의 중요성과 주로 소규모장서로 운영되는 학교도서관의 특성에 비추어 볼 때 특히, 학교도서관에 있어서 장서개발의 중요성은 재론할 필요가 없다. 그럼에도 불구하고 지금의 학교도서관은 자료구입 예산의 부족, 사서교사의 부재 또는 과도한 업무, 관리자의 무관심과, 잦은 전출 등으로 인하여 효과적인 장서구성에 어려움이 있다. 이러한 문제인식에 바탕하여 이 연구에서는 사서교사들의 인식을 바탕으로 현재 학교도서관의 장서가 실제로 어떻게 개발되고 관리되는지 그 현상적 과정을 파악하고 업무과정에서 발생하는 제반 상황을 분석하여 실천적 문제들을 제기하고자 하였다.

• Journal of Korean Neurosurgical Society
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• 제55권5호
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• pp.261-266
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• 2014

Objective : With the increased use of interspinous spacers in the treatment of lumbar stenosis, knowledge of the geometry of the interspinous space is important. To prevent dislodgment of an interspinous spacer, the accurate depth and width of the interspinous space needs to be established to facilitate the best intraoperative selection of correct spacer size. Methods : To determine the depth and width of the interspinous space, two methods are available which utilize plain film and magnetic resonance imaging (MRI). Data analysis of the interspinous depth and width was undertaken in 100 patients. Results : The standard deviations were variable, since skin thickness (zone 1) was altered by sex and age. The difference in the zone 1 distance between adjacent interspinous processes varied according to gender (p<0.05), but was not influenced by age [p=0.32 by analysis of variance between groups (ANOVA)]. Zone 2, the supraspinous, and zone 3, the interspinous ligament depths, comprise the operative working area during insertion of an interspinous spacer. There were no differences with regard to gender or age (p>0.05). For zones 6 and 7, the interspinous distances at the narrowest and widest points, respectively, were found to decrease with the aging process, but the decrease was not statistically significant. There were no differences with regard to gender (p>0.05). Conclusion : This study provides additional information on the interspinous space. This statistical data are valuable for use in the design of interspinous spacers.

• 한국압력기기공학회 논문집
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• 제16권1호
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• pp.117-124
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• 2020

3D printing is a technology that has significantly grown in recent years, particularly in the aerospace, defense, and medical sectors where it offers significant potential cost savings and reduction of the supply chain by allowing parts to be manufactured on-site rather than at a distance supplier. In nuclear industry, 3D printing technology should be applied according to the manufacturing trend change. For the application of 3D printing technology to the nuclear power plant, several problems, including the absence of code & standards of materials, processes and testing & inspection methods etc, should be solved. Preemptively, the improvement of reliability of 3D printing technology, including mechanical properties, structural performance, service performance and aging degradation of 3D printed parts should be supported. These results can be achieved by collaboration of many organizations such as institute, 3D printer manufacturer, metal powder supplier, nuclear part manufacturer, standard developing organization, and nuclear utility.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제31권2호
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• pp.80-87
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• 2020

Objectives: The prevalence of psychiatric disorders among young adults is different from that among younger or older age groups because of biological and environmental changes. The purpose of this study was to analyze the diagnostic distribution of psychiatric disorders in 19-30-year-old Koreans based on their age and gender using data from the Korean National Health Insurance Service (NHIS). Methods: From the 2011 medical claims sample data of NHIS of 1,375,842 people, we extracted the data of 221,038 people aged 19-30 years, including 106,232 (48.1%) men and 114,806 (51.9%) women. We evaluated the overall changes in the diagnostic distribution of psychiatric disorders over a 3-year period. Results: The diagnostic frequency in women was 13,627 (59.0%), which was significantly higher than that in men. "Other anxiety disorders" was the most common psychiatric disorder in both genders, followed by depressive episodes, somatoform disorders, "other neurotic disorders," and nonorganic sleep disorders. In men, attention-deficit/hyperactivity disorder or intellectual disabilities were not among the top 10 disorders. In women, no significant changes in major psychiatric disorders were seen over the 3-year period. Conclusion: These results reveal the trends of diagnostic distribution of mental illnesses depending on the development, particularly in young adulthood. It is necessary to identify whether such trends are due to biological or environmental factors, aging processes, or complex influences.

• 한국군사과학기술학회지
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• 제13권2호
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• pp.336-341
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• 2010

The burning interruption between the initiator and the delay column in a Zr-Ni K1 delay system used for a K510 fuze occurs with long-time storage. About 10 % failure probability of 15-years stored delay systems shows the failure mode in open literature. This paper shows storage lifetime improvement results for the delay system through changing the single-base delay column into double-base ones and controlling the manufacturing processes especially the initial inclusion of humidity. The double-base delay columns was implemented by inserting one delay column of fast burning rates between the initiator and the previous delay column of slow burning rates. Accelerated aging tests of the delay systems with double-base columns, and then the firing tests were performed to evaluate the improved lifetime. The double-base delay columns shows improved storage lifetime of the delay system through preventing the failure mode.