• 제목/요약/키워드: Aging factor

검색결과 878건 처리시간 0.035초

An approach of evaluation and mechanism study on the high and steep rock slope in water conservancy project

  • Yang, Meng;Su, Huaizhi;Wen, Zhiping
    • Computers and Concrete
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    • 제19권5호
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    • pp.527-535
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    • 2017
  • In this study, an aging deformation statistical model for a unique high and steep rock slope was proposed, and the aging characteristic of the slope deformation was better reflected. The slope displacement was affected by multiple-environmental factors in multiple scales and displayed the same tendency with a rising water level. The statistical model of the high and steep rock including non-aging factors was set up based on previous analyses and the study of the deformation and residual tendency. The rule and importance of the water level factor as a non-aging unit was analyzed. A partitioned statistical model and mutation model were established for the comprehensive cumulative displacement velocity with the monitoring study under multiple factors and multiple parameters. A spatial model was also developed to reflect and predict the whole and sectional deformation character by combining aging, deformation and space coordinates. A neural network model was built to fit and predict the deformation with a high degree of precision by mastering its feature of complexity and randomness. A three-dimensional finite element model of the slope was applied to approach the structure character using numerical simulations. Further, a three-dimensional finite element model of the slope and dam was developed, and the whole deformation state was analyzed. This study is expected to provide a powerful and systematic method to analyze very high, important and dangerous slopes.

중년여성의 노화불안 측정도구 개발 (Development of an Aging Anxiety Scale for Middle-Aged Women)

  • 이혜진;유미애
    • 대한간호학회지
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    • 제49권1호
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    • pp.14-25
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    • 2019
  • Purpose: This was a methodological study that aimed to develop a measurement scale for aging anxiety among middle-aged women. Methods: In this study, construct factors were extracted, and a conceptual framework was established through an extensive literature review and in-depth interviews with middle-aged women. Under the conceptual framework, 44 preliminary items were constructed, and a preliminary scale of 25 items was completed after two rounds of expert validation and item review. For this study, data were collected from 201 women aged 40~59 years, and the construct validity and reliability of the preliminary scale were verified. Results: To verify the construct validity, exploratory factor analysis was conducted. Four factors containing 19 items were extracted. Concurrent validity of the developed scale was verified with Pearson's correlation analysis. The final scale comprised 4 factors ("Social valueless", "Physical weakness", "Concern about changes in appearance", and "Expectations of old age") and 19 items. The Cronbach's ${\alpha}$ value was .91. Conclusion: The scale for measuring aging anxiety in middle-aged women developed in this study validly reflected the peculiarities of aging anxiety in middle-aged women, who experience many physical, emotional, and social changes. The scale can be said to reflect the cultural background, as it reflected real experiences gained through in-depth interviews with middle-aged women.

노화 관련 유전자의 후성유전학적 특성 분석 (Epigenetic Characterization of Aging Related Genes)

  • 류제운;이상철;유재수;김학용
    • 한국콘텐츠학회논문지
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    • 제13권8호
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    • pp.466-473
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    • 2013
  • 유전자 염기서열의 직접적인 변화 대신 염기의 수정 또는 변형을 통해 유전자 발현이 조절되는 후성유전은 크게 DNA 메틸화(methylation), 히스톤 변형(modification), ncRNA(non-coding RNA)에 의해 제어가 가능하다. 본 연구에서는 후성유전을 이해하기 위해 노화 관련 유전자를 대상으로 데이터베이스를 구축하고, DNA 메틸화를 중심으로 후성 유전학적 특성을 분석하였다. 유전자의 upstream 부위와 프로모터(promoter) 부위에 있는 CpG island(CGI)에 메틸화가 될 경우 유전자 발현을 억제하기 때문에 CGI를 중심으로 전체 유전자 그룹과 노화 관련 유전자 그룹간의 분포도를 비교 분석하였다. 또한 메틸화와 관련된 CGI로부터 얻은 메틸화 관련 motif 패턴을 이용하여 노화 유전자와의 관계를 분석하였다. 노화 관련 유전자의 CGI 분포는 전사인자 결합자리의 분포와 일치하였다. 본 연구에서 제공하는 DNA 메틸화 중심의 후성유전학적 정보는 노화 관련 유전자의 조절과 노화를 이해하는데 도움이 될 것으로 사료된다.

경년열화 기간에 따른 원자력발전소용 비안전등급 케이블의 연소특성 분석 (Combustion Characteristics Analysis of a Non-class 1E Cable for Nuclear Power Plants according to Aging Period)

  • 김민호;이석희;이민철;이상규;이주은
    • 한국안전학회지
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    • 제35권5호
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    • pp.22-29
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    • 2020
  • In this study, combustion and smoke release characteristics of a non-class 1E cable for nuclear power plants were investigated according to aging period. The aging was reproduced through an accelerated aging method for interval of 10 years :10, 20, 30 and 40 year, which was applied the Arrhenius equation. The cable was subjected to accelerated aging. In order to understand combustion and smoke release characteristics, the cone calorimeter test was performed according to the standard code of KS F ISO 5660-1. Heat release rate, mass loss rate, average rate of heat emission and smoke production rate were examined through cone calorimeter test. Fire performance index, fire growth index and smoke factor were derived from test results for the comparison of quantitative fire risk. When comparing the fire performance index and the fire growth index, the early fire risk tends to decrease as aging progresses, which might be attributed from the fact that the volatile substances of cables were evaporated. However, when comparing the heat release rate, average rate of heat emission and mass loss rate, which represent the mid and late periods of the fire risk, the values of accelerated aging cables were much higher than those of non-aged cable, which signifies the unstable formation of the char layer resulted in the change in the performance of flame retardants. In addition, the results from the smoke characteristics show that the accelerated aging cables were lager than the non-aged cables in terms of overall fire risk. These results can be used as baseline data when assessing fire risk of cables and establishing fire safety code for nuclear power plants.

충격공진법 및 복합법을 이용한 콘크리트의 강도 평가 기법 (Evaluation Technique of Concrete Strength Using Impact-Resonance and Combined Method)

  • 이광명;이회근;김동수;김지상
    • 콘크리트학회논문집
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    • 제11권4호
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    • pp.157-167
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    • 1999
  • Among several non-destructive testing methods, ultrasonic pulse velocity method and rebound index method have been widely used for the evaluation of concrete strength. However, such methods might not provide accurate estimated results since factors influencing the relationship between strength and either ultrasonic pulse velocity or rebound index are not considered. In this paper, the evaluation method of concrete strength using rod-wave velocity measured by impact-resonance method is proposed. A basic equation is obtained by the linear regression of velocity vs, strength data at specific age and then, aging factor is employed in the equation to consider the difference of the increasing rate between wave velocity and strength. Strengths predicted by the proposed equation agree well with test results. Furthermore, the combined method of rod-wave velocity and rebound index is proposed.

Silicate 형광체 증가에 대한 발광 특성 및 신뢰성 분석 (Analysis for luminescence property about an increase quantity of silicate phosphor and reliability)

  • 윤양기;장중순
    • 한국신뢰성학회지:신뢰성응용연구
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    • 제12권4호
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    • pp.275-285
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    • 2012
  • This paper presents a changes of luminescence property for converted white LEDs with the commercially available silicate phosphor. If silicate phosphor's quantity increase step by step. luminescence property will be changing. we analyze luminescence property for these change and carry out the high temperature aging test for 7,000 hours, the high temperature and humidity aging test for 7,000 hours for reliability. LED degradation not only results in reduced light output but also in color changes. so we monitor correlated color temperature (CCT), chromaticity coordinates(x, y) and spectrum intensity. Those results suggest that humidity factor more bad effect in color changes than temperature factor and Lighting quality is related with quantity of phosphor.

빈집발생의 유형과 발생에 영향을 미치는 요인에 관한 연구 - 인천광역시 사례를 중심으로 - (A Study on the Classification and Causative Factor of Vacant Houses - Focused on the Incheon Metropolitan City -)

  • 임창일;나인수
    • 한국BIM학회 논문집
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    • 제10권1호
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    • pp.23-29
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    • 2020
  • The vacant houses commonly observed in urban aging are considered to be representative signs of urban decline. Vacant houses are themselves vulnerable to security, and in particular, they are exposed to disasters due to poor management, which can accelerate the decline of the area. This study is to classify the area and analyze the causes and characteristics of the occurrence of vacant houses by type based on the data through the survey on the vacant houses in Incheon. This research analyze vacant house data survey so to characterized and categorized types of vacant houses. The criteria of vacant houses analysis are population density, population growth, aging extent. In conclusion there are four types of region in Incheon area according to housing types, hazard classes, building age and building areas. Type A is inner city, type B is mixed, type C is expandable and type D is unsular types.

한국 노인의 '성공적 노후 척도' 개발에 관한 연구 (The Study on the Development of the 'Successful Aging' Scale for Korean Elderly)

  • 김미혜;신경림
    • 한국노년학
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    • 제25권2호
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    • pp.35-52
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    • 2005
  • 본 연구는 한국 노인을 대상으로 성공적 노후의 성취 수준을 측정하기 위한 척도를 개발하고, 개발된 '성공적 노후 척도'의 일반화 가능성을 검증하기 위한 목적으로 (1)선행연구를 통한 문항 개발, (2)1차 조사를 통한 문항 내용 확인, (3)전문가 집단과 노인 포커스 그룹에 의한 내용타당도 검증, (4)2차 조사를 통한 성공적 노후의 구성요인 확인, 그리고 (5)3차 조사를 통한 구성타당도와 동시타당도 확인까지의 5단계 척도개발 과정들을 순차적으로 진행하였다. 한국 노인의 '성공적 노후 척도'는 총 30문항으로서 '자기 효능감을 느끼는 삶' '자녀 성공을 통해 만족하는 삶' '부부간의 동반자적 삶' 그리고 '자기통제를 잘 하는 삶'의 네 가지 하위요인으로 구성됨을 확인하였다. 그리고 '성공적 노후 척도'의 신뢰도는 Cronbach's a값 0.94로 높은 내적 일치도를 보였고, 확인적 요인분석을 통해 요인과 문항 간의 관계가 통계적으로 유의미함을 확인하여 요인구조에 대한 구성타당도를 확인하였다. 그리고 본 척도는 삶의 만족도와 0.69의 높은 상관관계를 보임으로서 동시타당도도 입증되었다. 이상과 같은 척도의 개발은 노인복지 실천현장에서 사회측정도구로 활용되는데 기여할 것이다.

젊은 흰쥐와 늙은 흰쥐에서 인터루킨-1$\alpha$로 유도된 급성폐손상에 관한 형태학적 연구 (Morphological Study of Acute Lung Injury Induced by Interleukin-1$\alpha$ Intratracheally in Young and Old Rats)

  • 조현국;이영만;박원학
    • 대한의생명과학회지
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    • 제3권2호
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    • pp.139-150
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    • 1997
  • 인터루킨-1 (IL-1)을 횐쥐의 기관지로 투여하여 급성 폐손상을 유도하고 폐세척액 내의 단백질 함량 측정과 조직학적, 미세구조적 관찰 및 폐조직 내 $H_2O$$_2$ 분포를 관찰하기 위한 세포화학적 실험을 수행하였다. 또한 노화가 급성 폐손상을 가중시키는 한 요소인지를 검토하였다. IL-1으로 유도된 급성 폐손상은 호중구의 침윤으로 인해 산화적 손상이 가해졌으며, 이로 인해 폐포강 내로 단백질 삼출과 백혈구의 유주가 발생하였다. 하지만 노화에 따른 $H_2O$$_2$분포 양상은 IL-1 투여군 4개월, 20개월간의 차이를 인정할 수 없었다. 따라서 본 연구결과를 통하여 급성호흡곤란 증후군 환자의 폐세척액에서 증가하는 IL-1을 흰쥐의 기관지 내로 투여하여 유도된 급성 폐손상은 호중구의 침윤으로 인한 산화적 손상이 매우 큰 원인으로 작용함을 형태적으로 확인할 수 있었으며, 노화 자체가 급성 폐손상을 가중시키지는 않는 것으로 사료되었다.

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