• Journal of Digital Convergence
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• v.19 no.11
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• pp.415-424
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• 2021

The purpose of the current study is to to examine the psychometric properties of the Subjective Agingwell Scale (SAS). Three hundred and forty two elders completed the SAS and the scales assessing subjective well-being, optimism, perceived control and adhering to healthy behavior. The 11-item SAS that displays good internal reliability and good fit to the three-factor model consisting of cognitive satisfaction, positive affect, and spiritual fullness. Correlational analyses with measures of subjective agingwell, subjective well-being, and optimism provide evidence for construct validity. Moreover, the results from hierarchical regression analyses show criterion-related validity of the SAS. This scale could be used in the field to measure and promote subjective agingwell.

• Journal of Family Resource Management and Policy Review
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• v.26 no.4
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• pp.15-24
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• 2022

This study was conducted to investigate the moderating effect of family health on the effect of stress on happiness. To achieve the purpose of this study, data from the Cheongdo Family Happiness Report were analyzed. The Cheongdo Family Happiness Report was conducted from October 13 to November 20, 2020, and a total of 286 family members' data were used for the final analysis. As a result of this study, stress was 2.77, and family healthy was 3.61. Happiness was 7.54, a sub-factor of happiness, life satisfaction was 5.25, positive emotion was 5.11, and negative emotion was 2.82. And Stress was found to have a negative effect on happiness, and family healthy was found to have a moderating effect on the effect of stress on happiness. Based on these results, this study proposes to consider family healthy in stress management programs and develop evidence-based family health programs to improve the happiness of local residents.

• Mycobiology
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• v.50 no.5
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• pp.366-373
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• 2022

Regulation of proper gene expression is important for cellular and organismal survival, maintenance, and growth. Abnormal gene expression, even for a single critical gene, can thwart cellular integrity and normal physiology to cause diseases, aging, and death. Therefore, gene expression profiling serves as a powerful tool to understand the pathology of diseases and to cure them. In this study, the difference in gene expression in Flammulina velutipes was compared between the wild type (WT) mushroom and the mutant one with clogging phenomenon. Differentially expressed transcripts were screened to identify the candidate genes responsible for the mutant phenotype using the DNA microarray analysis. A total of 88 genes including 60 upregulated and 28 downregulated genes were validated using the real-time quantitative PCR analysis. In addition, proteomic differences between the WT and mutant mushroom were analyzed using two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF). Interestingly, the genes identified by these genomic and proteomic analyses were involved in stress response, translation, and energy/sugar metabolism, including HSP70, elongation factor 2, and pyruvate kinase. Together, our data suggest that the aberrant expression of these genes attributes to the mutant clogging phenotype. We propose that these genes can be targeted to foster normal growth in F. velutipes.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.49 no.3
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• pp.225-230
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• 2023

In this study, the porous structure inside the hair were observed using an optical microscope without damaging the hair, and the porosity inside the hair was quantitatively expressed using the results. Experiments were conducted on the effect of the decrease in density inside the hair on the bending and tensile properties of the hair, and experiments on endogenous and extrinsic factors were conducted to find out the causes of the decrease in density inside the hair. As for the endogenous factor, the porosity of gray hair, one of the representative symptoms of aging, was compared with normal hair. As for extrinsic factors, it was observed that the internal density of hair decreased by surfactant and heat, which are factors that can cause hair damage in daily life. In addition, we confirmed whether it is possible to increase the internal density and luster of the hair by using an amino acids and material that can prevent hair lipid predisposition.

• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.443-448
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• 2023

Over the past five years, the number of patients with sleep disorders has increased by about 250,000 from 840,000 in 2017 to 1.09 million in 2021. In addition, sleep disorder is a factor that causes dementia risk factors, and furthermore, the population with sleep disorder is a very important policy issue in terms of stable health insurance financial management in the future in terms of national health management in the super-aging trend. Therefore, this study aims to establish an efficient treatment environment in medical institutions responsible for the current status of polysomnography and effective reimbursement policies for the recently increasing population with sleep disorders, and appropriate sleep management policies for future sleep disorders through correct implementation. We are trying to find out the actual condition and improvement plan through interviews with related organizations and experts.

• Journal of Korean Society of Rural Planning
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• v.28 no.4
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• pp.83-91
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• 2022

The goal of this study is to promote the spread of environmentally friendly agricultural products, which have been receiving a lot of attention lately, as a way to improve food safety and quality. As a result of the increased labor input, increased production costs, and an aging population, environmentally friendly agriculture is making it more difficult for farmers to expand their enterprises. In the meantime, consumers find it difficult to spread eco-friendly agricultural products due to their high expectations for safety and quality, as well as the desire to purchase products at a reasonable price. Previous studies have revealed differences in perceptions between eco-friendly agricultural producers and consumers. In light of this, this study divided consumers based on their characteristics (such as age, purchase history, health concerns, etc.), and different policies were proposed in order to increase purchasing factors for each group based on their characteristics. In order to gather information for this study, general citizens were asked about their perceptions of eco-friendly agricultural products, future purchase intentions and awareness, reliability, necessity, purpose, and information sources. A two-step clustering analysis was conducted using nominal and continuous variables simultaneously. The paper presents the three derived group differences (senior organic interest group, middle-aged organic interest group, and indifferent young organics) as well as group differences for the purchasing/non-purchasing factor analysis and policy improvement for each group. An eco-friendly agricultural product distribution proposal was made at the end of this article.

• Journal of Applied Biological Chemistry
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• v.65 no.1
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• pp.33-41
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• 2022

Esculetin (also known as 6, 7-dihydroxycoumarin) a type of coumarin, has been exhibited anti-inflammatory and anti-aging effects. Biorenovation is the microbe-mediated enhancement of biological efficacies and structurally diversified compounds relative to their substrate compounds. The production of different kinds of esculetin derivatives using Bacillus sp. JD3-7 and their effects on lipopolysaccharide (LPS)-triggered inflammatory response in RAW 26.7 cells were assessed. One of the biorenovation products, identified as esculetin 6-O-phosphate (ESP), at concentrations of 1.25, 2.5, and 5 μM inhibited the LPS-stimulated production of inflammation markers of nitric oxide synthase 2 and cyclooxygenase 2 as well as their respective enzymatic reaction products of nitric oxide and prostaglandin E2 in the order of increasing concentrations (1.25, 2.5, and 5 μM). Additionally, ESP treatment suppressed the LPS-stimulated secretion of pro-inflammatory cytokines of interleukin (IL)-1β, IL-6, and tumor necrosis factor- α. Furthermore, these anti-inflammatory effect of ESP was associated with the downregulation of mitogen-activated protein kinase signaling, that is, extracellular signal-regulated kinase, c-Jun NH2-terminal kinase, and p38 mitogen-activated protein kinase signaling pathways. This study would therefore provide interesting insights into the biorenovation-assisted generation of a novel anti-inflammatory compound. ESP may be used to develop treatments for inflammatory disorders.

• Journal of Distribution Science
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• v.21 no.7
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• pp.51-63
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• 2023

Housing is not only a basic requirement, but also a method to maintain stability and improve living. In the period of rapid social development which has a significant impact on the aging population, the housing issue is an impediment to Gen Y in Asia. Therefore, solving the housing conundrum is the most effective solution to other social problems. Purpose: This research is conducted to investigate factors influencing housing-option decisions of Gen Y and proposes recommendations to them as well as Governments and the real estate investors. Research design, data, and methodology: The Theory of Planned Behavior was employed with the expanded variables (Financial status, Location, Public services and Government incentives) based on literature review. Results: With 445 valid responses, almost all proposed hypotheses are accepted, which supports the positive interrelationship among variables. In the stage of data processing, we have determined the influence of each factor to the dependent variable "Actual Behavior", thereby helping real estate investors understand their desires, as well as improve the ability to meet customer needs. Conclusion: This is the basis to determine the influence of these factors, thereby providing recommendations to customers and what is more, giving real estate enterprises an insight of customers' demand in order to improve product quality and optimize the benefits of each party.

• Korean Journal of Exercise Nutrition
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• v.23 no.2
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• pp.28-33
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• 2019

[Purpose] Recent studies have shown that glucose-6-phosphate isomerase (GPI)-which is a glycolysis interconversion enzyme-reduces oxidative stress. However, these studies are limited to tumors such as fibrosarcoma, and there are no studies that have examined the effects of exercise on GPI expression in mice skeletal muscle. Furthermore, GPI acts in an autocrine manner thorough its receptor, autocrine motility factor receptor (AMFR); therefore, we investigated expression level changes of secreted GPI from skeletal muscle in in vitro study to examine the potential role of GPI on skeletal muscle. [Methods] First, we performed an in vitro study, to identify the condition that upregulates GPI levels in skeletal muscle cells; we treated C2C12 muscle cells with an exercise-mimicking chemical, AICAR. AICAR treatment upregulated GPI expression level in C2C12 cell and its secretomes. To confirm the direct effect of GPI on skeletal muscle cells, we treated C2C12 cells with GPI recombinant protein. [Results] We found that GPI improved the viability of C2C12 cells. In the in vivo study, the exercise-treated mice group showed upregulated GPI expression in skeletal muscle. Based on the in vitro study results, we speculated that expression level of GPI in skeletal muscle might be associated with muscle function. We analyzed the association between GPI expression level and the grip strength of the all mice group. The mice group's grip strengths were upregulated after 2 weeks of treadmill exercise, and GPI expression level positively correlated with the grip strength. [Conclusion] These results suggested that the exercise-induced GPI expression in skeletal muscle might have a positive effect on skeletal muscle function.

• Journal of the Economic Geographical Society of Korea
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• v.26 no.2
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• pp.73-95
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• 2023

The purpose of this study is to analyze the industrial structural changes and types of specialized in the shipbuilding cities, which are representative sectors of industrial city decline, and explore regional responses. Most cities designated as special areas for industrial crisis response in 2018 are specialized in shipbuilding. While the shift from prosperity to recession since the 2010s is the main factor, each city has responded differently to the industrial crisis. The analysis, targeting seven shipbuilding cities, shows that regions where large shipyards of major corporations with high industrial competitiveness are located have relatively less decline during business fluctuations, and there is a tendency for a decrease in industrial structural diversity during prosperous periods and an increase during recessionary periods. Based on the resistance and recoverability to industrial crises, the industrial paths of shipbuilding cities are classified into four types. Considering regional industrial structure and competitiveness, it is necessary to develop customized support strategies such as maintaining and declining shipbuilding industries and fostering new alternative industries.