• Title/Summary/Keyword: Aging Analysis

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Effect of Fermented Soybean on the Proliferation and Growth in HaCaT and Fibroblast Cell (대두 발효물이 인간 유래 피부세포의 증식 및 성장에 미치는 영향)

  • Kim, Eun-Joo;Han, Myung-Ryun;Lee, So-Young;Kim, Ae-Jung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.326-335
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    • 2021
  • This study was undertaken to determine the effect of fermented soybean extract and its fractions on skin cell proliferation and growth. The extract was procured by the pepsin and Lactobacillus rhamnosus fermentation of soybean. LC-MS analysis was performed subsequent to soybean fermentation, and cell viability was measured by the WST-1 assay. Cell proliferation was observed to increase after exposing cells to the fermented soybean extract and its fractions at all concentrations tested (0~2,000 ㎍/mL). In particular, compared to the normal control group and 120 % proliferation of the EGF (epidermal growth factor) positive control group, 160~180 % cell proliferation was achieved at 800 ㎍/ml, indicating the excellent potential as an application material for skin aging inhibition and skin cell regeneration. In addition, we also examined the effects of fermented soybean extract and its fractions on wound healing ability, in HaCaT cells and fibroblasts. Our results indicate excellent cell migration abilities after treatment with fermented soybean extract and its fractions, as compared to the control treatment. Similar cell migration abilities were observed in the positive control group (EGF). Taken together, our results indicate that fermented soybean extract and its fractions (F4 and F5) exert amelioratory effects as a natural material for skin.

Regional irrigation control modeling and regional climate characteristics Research on the correlation (지역별 관수제어 모델링 및 지역별 기후 특성과의 연관성에 관한 연구)

  • Jeong, Jin-Hyoung;Jo, Jae-Hyun;Kim, Seung-Hun;Choi, Ahnryul;Lee, Sang-Sik
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.14 no.3
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    • pp.184-192
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    • 2021
  • Domestic agriculture is facing real problems, such as a decrease in the population in rural areas, a shortage of labor due to an aging population, and increased risks due to the deepening of climate change. Smart farming technology is being developed to solve these problems. In the development of smart agricultural technology, irrigation control plays an important role in creating an optimal growth environment and is an important issue in terms of environmental protection. This paper is about the study of collecting and analyzing the rhizosphere environmental data of domestic paprika farms for the purpose of improving the quality of crops, reducing production costs, and increasing production. Irrigation control modeling presented in this paper Control modeling is to graphically present changes in a medium weight, feed, and drainage due to regional climatic features. To derive the graph, the parameters were determined through data collection and analysis, and the suggested irrigation control modeling method was applied to the collected rhizosphere environmental data to control irrigation in 6 regions (Gangwon-do, Chungnam, Jeonbuk, Jeonnam, Gyeongbuk, and Gyeongnam). The parameters were obtained and graphs were derived from them. After that, a study was conducted to analyze the derived parameters to verify the validity of the irrigation control modeling method and to correlate them with climatic features (average temperature and precipitation).

Study on Competitive Factors of Tourism Resources for Establishment of Jeju Health Tourism Model - Focusing on the Hierarchical Space Based on Medical Interference - (제주 헬스투어리즘 모델 정립을 위한 관광자원 경쟁요인 분석 - 의료간섭 기반 위계공간을 중심으로 -)

  • KIM, Hyo;JEONG, Heonkyu;KIM, Mincheol;CHOI, Yong-Bok
    • Journal of the Korean Association of Geographic Information Studies
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    • v.24 no.2
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    • pp.29-39
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    • 2021
  • The global aging phenomenon and new lifestyles have a worldwide attention to the new tourism form of health tourism. The purpose of this study is to analyze and suggest the competitive types of health tourism. Through the literature review, the theoretical base on the concept and type of health tourism and hierarchical spatial types such as medical space, semi-medical space, non-medical space, and natural healing space, based on medical intervention was established. A questionnaire survey was conducted for the professionals in Jeju area about tourism, health care, policy. As a result of analysis based on competitiveness advantage factors of Jeju health tourism, Jeju health tourism was confirmed to have higher importance in the natural healing space than the health service center space. Three kinds of resources such as natural resources, healing resources, and active resources of Jeju type health tourism were derived and applied to two hierarchical spaces, natural healing space and non-medical healing space, based on medical intervention.

Assets of the Elderly and their Life Satisfactions: Mediating Effects of Financial and Emotional Support with their Children Not Living Together (노인의 삶의 만족도에 자산이 미치는 영향: 비동거 자녀와의 경제적, 정서적 지지교환의 매개효과)

  • Won, Do-Yeon;Noh, Jae-Hyun;Shin, Yong-Seok
    • 한국노년학
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    • v.37 no.3
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    • pp.687-705
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    • 2017
  • The purpose of present study is to examine the effects of the elderly's assets on life satisfaction, and to examine the indirect effects, such as financial and emotional support exchange with their children, between their assets and life satisfaction. For this study purpose, the 5th data of the Korean Longitudinal Study of Aging (KLoSA) was used. Abstracted from the data, 1,977 cases only for the elderly over 65-year-old were analyzed by employing SPSS 23.0 and SPSS Process Macro. The analysis results are summarized as follows. First, the assets of the elderly had a positive direct effect on the satisfaction of life. Second, the elderly's assets indirectly affected the satisfaction of life through the financial support exchange with their child(ren). Lastly, the elderly's assets indirectly affected the satisfaction of life through the emotional support exchange with their child(ren). Based on these results, this study suggests practical and political implications in terms of social welfare for the elderly's life satisfaction, so as to facilitate the elderly's assets accumulation, and to enhance support exchange between the elderly and their child(ren).

Associations of Longitudinal Changes in Marital Satisfaction and Depression among Elderly Couples: An Application of the Dyadic Growth Actor-Partner Interdependence Model (노년기 부부의 관계만족도와 우울의 종단적 변화 사이의 관련성: 이자성장 행위자-상대방 상호의존 모형의 적용)

  • Lee, Ka-Hyun;Jeong, Seong-Chang;Jahng, Seungmin
    • Survey Research
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    • v.18 no.4
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    • pp.25-59
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    • 2017
  • The current study investigated how elderly husbands and wives' marital satisfaction and depression change over time and examined how changes in marital satisfaction account for changes in depression between and within the dyads. The longitudinal dyadic data from the first wave(2006) to the fifth wave(2014) of the Korean Longitudinal Study of Aging(KLoSA), collected by the Korea Employment Information Service, were used for the analyses. Because husbands and wives are interdependent within couples, we applied statistical models for dyadic data. The dyadic growth model(DGM) was used to model the trajectories of marital satisfaction and depressive symptoms. In order to analyze the association of these growth factors, we proposed the dyadic growth actor-partner interdependence model(DG-APIM) and applied the model to the data. The results showed that on average the husbands' marital satisfaction was higher but decreased faster over the course of the study than the wives'. It also showed that the average depression of the husbands was lower than that of the wives but the husbands' depression increased faster than the wives' over the course of the study. The variance of the averages of husbands' (wives's) depression was accounted for by that of wives'(husbands') marital satisfaction, showing a partner effect. The variance of the slopes of husbands'(wives') depression was accounted for by that of marital satisfaction of themselves, showing an actor effect. The results showed that there is a longitudinal interdependence between husbands and wives' marital satisfaction and depression and supported the marital discord model of depression.

The Effects of Multidimensional Social Isolation on Physical and Mental Health: Analysis of Interaction Effects of Age Groups (다차원적 사회적 고립이 신체적·정신적 건강에 미치는 효과: 연령집단의 상호작용효과 분석)

  • Lee, Sangchul;Cho, Joonyoung
    • 한국사회정책
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    • v.24 no.2
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    • pp.61-86
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    • 2017
  • Along with the well-established evidence on the negative effect of social isolation on physical and mental health, increasing attention has been paid to multi-dimensional nature of social isolation. One line of study on social isolation has discussed different pathways between objective and subjective social isolation and health. Another stream of the research focused on the possibly non-linear association between social isolation and health by age cohort groups. Drawing from the two lines of research, this study aimed at empirically examine to what extent objective and subjective social isolation are associated with physical and mental health independently and how the associations vary by three age cohorts(i.e. the middle-aged, the young old, the old-old). Data came from the first wave of Korean Social Life, Health and Aging Project (KSHAP) (N= 814). Findings showed 1) objective subjective isolation were significantly related with worse physical and mental health, interestingly, subjective social isolation was associated with mental health only, 2) pattern of association between social isolation and physical health varied by age cohorts. Specifically, compared to the middle-aged, the young old with higher objective social isolation exhibited lower level of physical health, while the old-old with higher subjective social isolation were likely to experience lower physical health. Based on the findings, we discussed implications and suggestions for future research and relevant policy/program development for ameliorating objective and subjective social isolation.

Anti-Oral Microbial Activity and Anti-Inflammatory Effects of Rosmarinic Acid in Lipopolysaccharide-Stimulated MC3T3-E1 Osteoblastic Cells on a Titanium Surface

  • Jeong, Moon-Jin;Lim, Do-Seon;Heo, Kyungwon;Jeong, Soon-Jeong
    • Journal of dental hygiene science
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    • v.20 no.4
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    • pp.221-229
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    • 2020
  • Background: The purpose of this study was to investigate the anti-oral microbial activity and anti-inflammatory effects of rosmarinic acid (RA) in lipopolysaccharide (LPS)-stimulated MC3T3-E1 osteoblastic cells on a titanium (Ti) surface during osseointegration, and to confirm the possibility of using RA as a safe natural substance for the control of peri-implantitis (PI) in Ti-based dental implants. Methods: A disk diffusion test was conducted to confirm the antimicrobial activity of RA against oral microorganisms. In order to confirm the anti-inflammatory effects of RA, inflammatory conditions were induced with 100 ng/ml of LPS in MC3T3-E1 osteoblastic cells on the Ti surface treated with or without 14 ㎍/ml of RA. The production of nitric oxide (NO) and prostaglandin E2 (PGE2) in LPS-stimulated MC3T3-E1 osteoblastic cells on the Ti surface was confirmed using an NO assay kit and PGE2 enzyme-linked immunosorbent assay kit. Reverse transcription polymerase chain reaction and western blot analysis were performed to confirm the expression of interleukin (IL)-1β and tumor necrosis factor (TNF)-α in total RNA and protein. Results: RA showed weak antimicrobial effects against Streptococcus mutans and Escherichia coli, but no antimicrobial activity against the bacteria Aggregatibacter actinomycetemcomitans and the fungus Candida albicans. RA reduced the production of pro-inflammatory mediators, NO and PGE2, and proinflammatory cytokines, TNF-α and IL-1β, in LPS-stimulated MC3T3-E1 osteoblastic cells on the Ti surface at the protein and mRNA levels. Conclusion: RA not only has anti-oral microbial activity, but also anti-inflammatory effects in LPS-stimulated MC3T3-E1 osteoblasts on the Ti surface, therefore, it can be used as a safe functional substance derived from plants for the prevention and control of PI for successful Ti-based implants.

A Study of Health Literacy, Self-Management Knowledge, and Self-Care Behaviors in Elderly with Hemodialysis (혈액투석 노인의 건강문해력, 자가관리지식과 자가간호행위에 관한 연구)

  • Yu, Hye Seon;Lee, Young Whee;Kim, Hwasoon
    • The Journal of the Korea Contents Association
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    • v.21 no.6
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    • pp.609-619
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    • 2021
  • The purpose of this study was not only to identify the level of health literacy, self-management knowledge and self-care behavior, but also to identify the relations those variables in elders with hemodialysis. The subjects of this study are 193 patients from dialysis clinics of nine hospitals in Incheon who aging over 60 years old. Data collection was conducted by using Health Literacy Scale, Self-Management Knowledge Scale, and Self-Care Behavior Scale. The data were analysed by descriptive analysis, t-test, ANOVA, and Pearson correlation coefficient using SPSS statistics 23.0 program. In the results, average score of subjects' health literacy, self-management knowledge and self-care behavior were 13.66(±2.09), 13.33(±1.85) and 63.95(±10.32), respectively. There were significant positive correlation between self-management knowledge and health literacy (r=0.37, p<.001) and reading comprehension part which is subscale in health literacy (r=.25, p=.001). Also, there was significant positive correlation between self-management knowledge and self-care behavior (r=0.15, p<.05). According to the above results, for improving the self-care behaviors in elders with hemodialysis, it is necessary to provide tailored education based on his/her level of health literacy.

A Study on Life Cycle Cost According to Bridge Condition (교량 상태에 따른 생애주기비용 영향 분석)

  • Park, Jun-Yong;Lee, Keesei
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.802-809
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    • 2021
  • To cope with the increasing maintenance costs due to aging, the maintenance cost was evaluated from the perspective of asset management. The maintenance cost can be predicted based on the condition of the bridge, and the life cycle cost is used as an index. In general, the condition of a bridge has a wide distribution characteristic depending on the deterioration, load, and material characteristics. In this paper, to evaluate the effect of the bridge conditions on the life cycle cost, condition prediction models were constructed considering the service life, deterioration rate, and inspection error, which are the main variables of the bridge condition and life cycle cost calculation. In addition, condition prediction models were constructed based on the distribution of the health index to estimate the upper and lower bounds of the life cycle costs that can occur in individual bridges. Life cycle cost analysis showed that the life cycle cost differed significantly according to the condition of the bridge. Accordingly, research will be needed to increase the reliability of predicting the life cycle cost of individual bridges.

A Study on Structural Analysis for Improving Driving Performance of Agricultural Electric Car (농업용 전기운반차의 주행성능 향상을 위한 구조해석에 관한 연구)

  • Jo, Jae-Hyun;Lee, Sang-Sik
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.13 no.6
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    • pp.556-561
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    • 2020
  • The aging and declining agricultural population in the modern society requires improvement of the agricultural environment and is one of the representative problems. And since most of the work systems always require a transport work, the ratio of labor consumed in the transport work is very high. Accordingly, many types of transport vehicles are being developed and sold, and in the early days, most of them are powered transport vehicles using fossil fuels. However, it is paying attention to next-generation eco-friendly energy such as hydrogen, fuel cells, solar power, and bio due to the strengthening of international environmental regulations such as global warming and the Convention on Climate Change and the depletion of fossil fuels. Therefore, in this study, the ultimate goal is to develop an eco-friendly, easy-to-operate, safe agricultural electric vehicle that replaces fossil fuels. It was designed with a focus on controlling a wide range of vehicle speeds and securing stability of electric agricultural vehicles. Considering the performance and design, it is composed of a frame, a driving part, a steering part, and a controller system, and we are going to review and manufacture each part. It is believed that the manufactured electric vehicle for agriculture can be easily and conveniently operated in an agricultural society where young manpower is scarce, and can be helpful to the agricultural society through high efficiency.