• Radiation Oncology Journal
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• v.25 no.4
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• pp.278-282
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• 2007

Purpose: Diffuse pigmented villonodular synovitis (PVNS) is an uncommon aggressive synovial proliferative disorder of unknown etiology affecting the joint linings. Though a histologically benign inflammatory process, because of its aggressive growth with bone destruction or recurrence, it is frequently suggested to occur as a low malignant neoplasm. Optimal treatment is surgery, but the local recurrence rate after radical synovectomy for diffuse PVNS is relatively high due to the infiltrative growth pattern. External beam radiotherapy with moderate doses or intra-articular instillation of radioactive isotopes may improve the likelihood of local control and long-term function in patients with incompletely resected or recurrent diffuse PVNS. I report one case of diffuse PVNS of the right knee joint treated with arthroscopic synovectomy and external beam radiotherapy is presented.

• The Journal of the Korea Contents Association
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• v.12 no.2
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• pp.369-387
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• 2012

Based on the survey data, this study focused venture firms examines how organizational resources and capabilities along with its external environmental conditions have an effect on its strategy and performance. In particular, this article attempts, by performing a binary logistic regression analysis, to identify the venture-specific importance and priority of the factors that may influence firms' strategy patterns, with multiple regression analysis on the relationships between some variables included in the model. The survey was conducted from October 1, 2010 through October 30, 2010. The results of this study are the following. First, the more firms are exposed to high industry growth and low competitive intensity, the higher chance they get to pursuit aggressive strategy. And then a firm seeks aggressive strategy, when it has more technological resources and human resources. Third, environmental uncertainty, industry growth, technological resources, human resources, financial resources and marketing capabilities have positive effects on firm's performance. But, competitive intensity has no direct influence firm's performance. Finally, CEO competence directly influences firm's performance, but the interaction. of CEO competence with other variables is not significant.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.1 s.173
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• pp.156-162
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• 2000

Sensitized STS 304 stainless steel crack growth rate(CGR) in high temperature water was investigated under trapezoidal wave loading test using fracture mechanics techniques. The CGR, due to stress corrosion cracking(SCC), were systematically measured as a function of the stress intensity factor and stress. holding time under trapezoidal wave loading. In high temperature water, CGR was enhanced by a synergistic effects in combination with an aggressive environment and mechanical damage. The CGR, $(da/dN)_{env}$ was basically described as a summation of the environmentally assisted crack growth rate $(da/dN)_{SCC}$, $(da/dN)_{CF}$ and fatigue crack growth rate in air $(da/dN)air,. The CGR, $(da/dN)_{env}$, increased linearly with increasing stress holding time. The CGR, $(da/dN)_{SCC}$ decreased linearly with increasing stress holding time. Fracture surface mode varied from trans-granular cracking to inter-granular cracking with increasing stress holding time.

• Clinical and Experimental Pediatrics
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• v.60 no.3
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• pp.64-69
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• 2017

Purpose: The goal of nutritional support for very-low-birth-weight (VLBW) infants from birth to term is to match the in utero growth rates; however, this is rarely achieved. Methods: We evaluated postdischarge growth patterns and growth failure in 81 Korean VLBW infants through a retrospective study. Weight and height were measured and calculated based on age percentile distribution every 3 months until age 24 months. Growth failure was defined as weight and height below the 10th percentile at 24 months. For the subgroup analysis, small-for-gestational age (SGA) and extremely low birth weight (ELBW) infants were evaluated. The growth patterns based on the Korean, World Health Organization (WHO), or Centers for Disease Control and Prevention (CDC) standard were serially compared over time. Results: At postconception age (PCA) 40 weeks, 47 (58%) and 45 infants (55%) showed growth failure in terms of weight and height, respectively. At PCA 24 months, 20 infants (24%) showed growth failure for weight and 14 (18%) for height. Growth failure rates were higher for the SGA infants than for the appropriate-weight-for-gestational age infants at PCA 24 months (P=0.045 for weight and P=0.038 for height). Growth failure rates were higher for the ELBW infants than for the non-ELBW infants at PCA 24 months (P<0.001 for weight and P=0.003 for height). Significant differences were found among the WHO, CDC, and Korean standards (P<0.001). Conclusion: Advancements in neonatal care have improved the catch-up growth of VLBW infants, but this is insufficient. Careful observation and aggressive interventions, especially in SGA and ELBW infants, are needed.

• Journal of Information Technology Applications and Management
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• v.21 no.4_spc
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• pp.485-499
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• 2014

Sharing Economy is the modern main item with ICT Development. Of course sharing economic item is the old and long run mainstream, but by the ICT technological development sharing economy is the fostering and affluent factors in the world economic growth. Though, in Korea, till now sharing economy is minimal, that will growth sharply. We can track various business models of sharing economy. Sharing economy is to buy use right not ownership. With the sharing economic business model wee can make also financial sharing model. In finance model we can divide two kind models. First, we can trace small size lending model with p2p type. And second, we can make financial information transaction model. But till now sharing economic system is not activated, because of many reasons. To activate, first we have to set law and various standards, and also government actively support many sharing economy firms and institutions. To catch up developed countries in the field of sharing economy we have to make aggressive and flexible rules and standards.

• Clinical and Experimental Pediatrics
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• v.57 no.11
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• pp.465-471
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• 2014

Inflammatory bowel disease (IBD) is a chronic relapsing disorder of unknown etiology, which is believed to be multifactorial. Recently, the incidence of pediatric IBD has steeply increased in Korea since 2000. Poorly controlled disease activity can result in complications such as intestinal fistulae, abscess, and stricture, as well as growth retardation and delayed puberty in children. Because of a lack of confirmative tests, various diagnostic modalities must be used to diagnose IBD. Onset age, location, behavior, and activity are important in selecting treatments. Monogenic IBD must be excluded among infantile and refractory very-early-onset IBD. Early aggressive therapy using biologics has recently been proposed for peripubertal children to prevent growth failure and malnutrition.

• Structural Engineering and Mechanics
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• v.75 no.4
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• pp.455-464
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• 2020

Reinforcement corrosion is one of the major problems in the durability of reinforced concrete structures exposed to aggressive environments. Deterioration caused by reinforcement corrosion reduces the durability and the safety margin of concrete structures, causing excessive costs in managing these structures safely. This paper aims to investigate the effects of reinforcement corrosion on the load bearing capacity deterioration of the corroded reinforced concrete structures. A new analytical method is proposed to predict the crack growth of cover concrete and evaluate the residual strength of concrete structures with corroded reinforcement failing in bond. The structural performance indicators, such as concrete crack growth and flexural strength deterioration rate, are assumed to be a stochastic process for lifetime distribution modelling of structural performance deterioration over time during the life cycle. The Weibull life evolution model is employed for analysing lifetime reliability and estimating remaining useful life of the corroded concrete structures. The results for the worked example show that the proposed approach can provide a reliable method for lifetime performance assessment of the corroded reinforced concrete structures.

• Proceedings of the KSME Conference
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• 2000.04a
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• pp.67-72
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• 2000

Demand for now nondestructive evaluation are growing to detect fatigue crack growth behavior to predict long term performance of materials and structure in aggressive environments especially when they are In non-visible area. Acoustic emission technique is well suited to these problems and has drawn a keen interests because of its dynamic detection ability, extreme sensitivity and location of growing defects. In this study, we analysed acoustic emission signals obtained in fatigue and tensile test of high strength fire resistance steel for frame structure with time-frequency analysis methods. The main frequency range is different in the noise and the fatigue crack propagation. It could be classified that it were also generated by composite fracture mechanics of cleavage, dimple, inclusion separation etc.

• East Asian Economic Review
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• v.25 no.1
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• pp.73-97
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• 2021

China has experienced many structural changes in the process of economic development over the past three decades. Using a time-varying parameter VAR model with stochastic volatility and mixture innovations, this study investigates whether such structural changes in, especially tools and operational aims of monetary policy, affect the monetary transmission mechanism. We find that impulse responses of output growth and inflation to monetary shocks have substantially increased and then reversed to decrease around 2005-2006. This time variation is mainly caused by changes in the monetary transmission mechanism, i.e., the manner in which main macroeconomic variables respond to policy shocks, rather than by changes in volatilities of exogenous shocks. The result implies that aggressive monetary policy to facilitate economic growth in the developing economies may be legitimized, unless it causes inflation seriously.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.16
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• pp.6829-6835
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• 2014

Chemotherapy is the primary therapy for malignant lymphoma (ML). However, the clinical outcome is still far from satisfactory. Consequently, an understanding of the mechanism of modulating cancer cell invasion, migration and metastasis is important for the development of more effective chemotherapeutic agents. FNC, 2'-deoxy-2'-${\beta}$-fluoro-4'-azidocytidine, a novel cytidine analogue, has demonstrated significantly inhibitory effects on proliferation of several non-Hodgkin lymphoma (NHL) cell lines. A previous study indicated that FNC effectively inhibited the growth of Raji and JeKo-1 cells in dose-time dependent effects with $IC_{50}$ values of $0.2{\mu}M$ and $0.097{\mu}M$, respectively. This study was focused on investigating the anti-invasive properties of FNC on NHL cells and its potential mechanisms of action. Cell adhesion and transwell chamber assays were utilized to investigate the anti-invasive effects of FNC on Raji and JeKo-1 cells. Real-time PCR and Western blotting were employed to qualify the expression of ${\beta}$-catenin, the glycogen synthase kinase-3 beta (GSK-$3{\beta}$), E-cadherin vascular endothelial growth factor (VEGF), matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9). The results revealed that FNC remarkably inhibited the adhesion, migration and invasion of two human aggressive non-Hodgkin lymphoma cell lines in a dose dependent manner. Furthermore, ${\beta}$-catenin, MMP-2, MMP-9, VEGF mRNA and protein levels were decreased after FNC treatment, while GSK-$3{\beta}$ and E-cadherin increased. Our studies thus provide evidence and a rationale that FNC may offer an effective chemotherapeutic agent by regulating the invasion and metastasis of aggressive non-Hodgkin lymphoma via inhibition of the Wnt/${\beta}$-catenin signaling pathway.