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Diffuse Pigmented Villonodular Synovitis of the Knee: Case Report  

Choi, Sang-Gyu (Department of Radiation Oncology, Dankook University Hospital)
Publication Information
Radiation Oncology Journal / v.25, no.4, 2007 , pp. 278-282 More about this Journal
Abstract
Purpose: Diffuse pigmented villonodular synovitis (PVNS) is an uncommon aggressive synovial proliferative disorder of unknown etiology affecting the joint linings. Though a histologically benign inflammatory process, because of its aggressive growth with bone destruction or recurrence, it is frequently suggested to occur as a low malignant neoplasm. Optimal treatment is surgery, but the local recurrence rate after radical synovectomy for diffuse PVNS is relatively high due to the infiltrative growth pattern. External beam radiotherapy with moderate doses or intra-articular instillation of radioactive isotopes may improve the likelihood of local control and long-term function in patients with incompletely resected or recurrent diffuse PVNS. I report one case of diffuse PVNS of the right knee joint treated with arthroscopic synovectomy and external beam radiotherapy is presented.
Keywords
Diffuse pigmented villonodular synovitis; Arthroscopic synovectomy; Radiotherapy;
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1 Ustinova VF, Podilashuk EL, Rodionova SS. Combined treatment of the diffuse form of pigmented villonodular synovitis. Med Radiol (Mosk) 1986;31:27-31   PUBMED
2 Atmore WG, Dahlin DC, Ghormey RK. Pigmented villonodular synovitis - a clinical and pathologic study. Minn Med 1956;39:196-202   PUBMED
3 Flandry F, McCann SB, Hughston JC, McCann SB, Kurtz DM. Roentgenographic findings in pigmented villonodular synovitis of the knee. Clin Orthop 1989;247:208-219
4 Cotten A, Flipo RM, Chastanet P, Desvigne-Noulet MC, Duquesnoy B, Delcambre B. Pigmented villonodular synovitis of the hip: review of radiographic features in 58 patients. Skeletal Radiol 1995;24:1-6   DOI
5 Sabat S, Kollender Y, Merimsky O, et al. The use of surgery an yttrium 90 in the management of extensive and diffuse pigmented villonodular synovitis of large joints. Rheumatology(Oxford) 2002;41:1113-1118   DOI   ScienceOn
6 O'Sullivan B, Cummings B, Catton C, et al, Outcome following radiation treatment for high-risk pigmented villonodular synovitis. Int J Radiat Oncol Biol Phys 1995;32:777-786   DOI   ScienceOn
7 Sakkers RJ, de Jong D, van der Hul RO. X-chromosome inactivation in patients who have pigmented villonodular synovitis. J Bone Joint Surj Am 1991;73:1532-1536   DOI
8 Kat S, Kutz R, Elbracht T, et al. Radiosynovectomy in pigmented villonodular synovitis. Nuklearmedizin 2000;39:209- 213   DOI   PUBMED
9 Brien EW, Sacoman DM, Mirra JM. Pigmented villonodular synovitis of the foot and ankle. Foot Ankle Int 2004;25:908-913   DOI
10 Hamlin BR, Duffy GP, Trousdale RT, Morrey BF. Total knee arthroplasty in patients who have pigmented villonodular synovitis. J Bone Joint Surg [Am] 1998;80:76-82   DOI   PUBMED
11 Rao AS, Vigorita VJ. Pigmented villonodular synovitis (giantcell tumor of the tendon sheath and synovial membrane). A review of eighty-one cases. J Bone Joint Surg Am 1984;66:76- 94   DOI   PUBMED
12 Jaffe HL, Lichtenstein L, Sutro CJ. Pigmented villonodular synovitis, bursitis, and tenosynovitis. Arch Pathol 1941;31:731- 765
13 Chin KR, Barr SJ, Winalski C, et al. Treatment of advanced primary and recurrent diffuse pigmented villonodular synovitis of the knee. J Bone Joint Surg Am 2002;84-A: 2192-2202   PUBMED
14 Granowitz SP, D'Antonio J, Mankin HL. The pathogenesis and long-term end results of pigmented villonodular synovitis. Clin Orthop 1976;114:335-351
15 Boerbooms AM, Bujjs WC, Danen M, Van de Putte LB, Vandenbroucke JP. Radio-synovectomy in chronic synovitis of the knee joint in patients with rheumatoid arthritis. Eur J Nucl Med 1985;10:446-449   PUBMED