• 제목/요약/키워드: Aggregation Characteristics

검색결과 260건 처리시간 0.022초

Measurement of cell aggregation characteristics by analysis of laser-backscattering in a microfluidic rheometry

  • Shin, Se-Hyun;Hou, J.X.;Suh, Jang-Soo
    • Korea-Australia Rheology Journal
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    • 제19권2호
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    • pp.61-66
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    • 2007
  • The aggregation characteristics of red blood cells (RBCs) are known as important factors in the microvascular flow system, and increased RBC aggregation has been observed in various pathological diseases, such as thrombosis and myocardial infarction. This paper describes a simple microfluidic device for measuring the RBC aggregation by integrating a microfluidic slit rheometry and laser-backscattering technique. While a decreasing-pressure mechanism was applied to the microfluidic rheometry, a syllectogram (the light intensity versus time) showed an initial increase and a peak caused by the high shear stress-induced disaggregation, immediately followed by a decrease in the light intensity due to RBC aggregation. The critical shear stress (CST) corresponding to the peak intensity was examined as a new index of the RBC aggregation characteristics. The CST of RBCs increased with increasing aggregation-dominating protein (fibrinogen) in the blood plasma. The essential feature of this design was the combination of the rheometric-optic characterization of RBC aggregation with a microfluidic chip, which may potentially allow cell aggregation measurements to be easily carried out in a clinical setting.

Topology Aggregation for Hierarchical Wireless Tactical Networks

  • Pak, Woo-Guil;Choi, Young-June
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제5권2호
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    • pp.344-358
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    • 2011
  • Wireless tactical network (WTN) is the most important present-day technology enabling modern network centric warfare. It inherits many features from WMNs, since the WTN is based on existing wireless mesh networks (WMNs). However, it also has distinctive characteristics, such as hierarchical structures and tight QoS (Quality-of-Service) requirements. Little research has been conducted on hierarchical protocols to support various QoS in WMN. We require new protocols specifically optimized for WTNs. Control packets are generally required to find paths and reserve resources for QoS requirements, so data throughput is not degraded due to overhead. The fundamental solution is to adopt topology aggregation, in which a low tier node aggregates and simplifies the topology information and delivers it to a high tier node. The overhead from control packet exchange can be reduced greatly due to decreased information size. Although topology aggregation is effective for low overhead, it also causes the inaccuracy of topology information; thus, incurring low QoS support capability. Therefore, we need a new topology aggregation algorithm to achieve high accuracy. In this paper, we propose a new aggregation algorithm based on star topology. Noting the hierarchical characteristics in military and hierarchical networks, star topology aggregation can be used effectively. Our algorithm uses a limited number of bypasses to increase the exactness of the star topology aggregation. It adjusts topology parameters whenever it adds a bypass. Consequently, the result is highly accurate and has low computational complexity.

STM을 이용한 Merocyanine Dye J-aggregation 특성관찰 (The investigation into Merocyanine Dye J-aggregation of characteristic by STM)

  • 양창헌;이지윤;최원석;권영수
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2008년도 Techno-Fair 및 합동춘계학술대회 논문집 전기물성,응용부문
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    • pp.165-166
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    • 2008
  • We investigate characteristics of J-aggregation as take advantage of LB technic. In order to confirm the applications possible for the molecular electronic device, the morphological properties of merocyanine dye were investigated by AFM. $\pi$-A curves investigated the surface pressure of the LB film from a liquid to a solid state ranged between 90 and 100 mN/m. We observed aggregation and it's characteristics by using visible reflection spectroscopy. We have observed morphology of merocyanine dye on gold surface by STM. focuses on results obtained in mercocyanide dye of J-aggregation. When LB films of merocyanine dye are mixed with arachidic acid, J-aggregate formation is exhibited. J-aggregate formation has been serving as typical systems in revealing the physical and structural aspects of nano-sized molecular aggregates constructed as muiltilayers.

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용담댐 유역에서 식생 이질성이 FLO-2D 유량 산정에 미치는 영향 (Impact of Vegetation Heterogeneity on Rainfall Excess in FLO-2D Model : Yongdam Catchment)

  • 송호준;이길하
    • 한국환경과학회지
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    • 제28권2호
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    • pp.259-266
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    • 2019
  • Two main sources of data, meteorological data and land surface characteristics, are essential to effectively run a distributed rainfall-runoff model. The specification and averaging of the land surface characteristics in a suitable way is crucial to obtaining accurate runoff output. Recent advances in remote sensing techniques are often being used to derive better representations of these land surface characteristics. Due to the mismatch in scale between digital land cover maps and numerical grid sizes, issues related to upscaling or downscaling occur regularly. A specific method is typically selected to average and represent the land surface characteristics. This paper examines the amount of flooding by applying the FLO-2D routing model, where vegetation heterogeneity is manipulated using the Manning's roughness coefficient. Three different upscaling methods, arithmetic, dominant, and aggregation, were tested. To investigate further, the rainfall-runoff model with FLO-2D was facilitated in Yongdam catchment and heavy rainfall events during wet season were selected. The results show aggregation method provides better results, in terms of the amount of peak flow and the relative time taken to achieve it. These rwsults suggest that the aggregation method, which is a reasonably realistic description of area-averaged vegetation nature and characteristics, is more likely to occur in reality.

Mutation Effects on FAS1 Domain 4 Related to Protein Aggregation by Molecular Dynamics Simulations and Solvation Free Energy Analysis

  • Cho, Sunhee;Ham, Sihyun
    • EDISON SW 활용 경진대회 논문집
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    • 제4회(2015년)
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    • pp.70-75
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    • 2015
  • Fasciclin 1 (FAS1) is an extracellular protein whose aggregation in cornea leads to visual impairment. While a number of FAS1 mutants have been studied that exhibit enhanced/decreased aggregation propensity, no structural information has been provided so far that is associated with distinct aggregation potential. In this study, we have investigated the structural and thermodynamic characteristics of the wild-type FAS1 and its two mutants, R555Q and R555W, by using molecular dynamics simulations and three-dimensional reference interaction site model (3D-RISM) theory. We find that the hydrophobic solvent accessible surface area increases due to hydrophobic core repacking in the C-terminus caused by the mutation. We also find that the solvation free energy of the mutants increases due to the enhanced non-native H-bonding. These structural and thermodynamic changes upon mutation contribute to understand the aggregation of these mutants.

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UV 조사에 의한 메로시아닌 색소 LB박막의 J-aggregation 특성 (J-aggregation Property of Merocyanine Dye LB Thin Film by UV Irradiation)

  • 양창헌;이지윤;권영수
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2008년도 춘계학술대회 논문집 센서 박막재료연구회 및 광주 전남지부
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    • pp.123-124
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    • 2008
  • We investigate characteristics of J-aggregation as take advantage of LB technic. In order to confirm the applications possible for the molecular electronic device, the morphological properties of merocyanine dye were investigated by AFM. $\pi$-A curves investigated the surface pressure of the LB film from a liquid to a solid state ranged between 90 and 100 mN/m. We observed aggregation and it's characteristics by using visible reflection spectroscopy. This paper focuses on results obtained in mercocyanide dye. When LB films of merocyanine dye are mixed with arachidic acid, J-aggregate formation is exhibited. J-aggregate formation has been serving as typical systems in revealing the physical and structural aspects of nano-sized molecular aggregates constructed as muiltilayers.

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Bypass-Based Star Aggregation Using Link Attributes for Improving the Information Accuracy

  • Kwon, Sora;Jeon, Changho
    • Journal of Communications and Networks
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    • 제17권4호
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    • pp.428-439
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    • 2015
  • In this study, we present an approach for reducing the information inaccuracy of existing star aggregation based on bypass links when there are multi-constraint QoS parameters in asymmetric networks. In our approach, bypass links with low similarity are selected. Links that are not chosen as bypass links are included in each group depending on the star's link characteristics. Moreover, each link group is aggregated differently according to the similarity of the links that make up the group. The selection of a bypass link by using link similarity reduces the existing time complexity of O($N^3$) to O(N) by virtue of the simplification of the selection process. In addition, the adaptive integration according to the characteristics of the links in each group is designed to reduce the information inaccuracy caused by static aggregation. Simulation results show that the proposed method maintains low information distortion; specifically, it is 3.8 times lower than that of the existing method, even when the number of nodes in a network increases.

개별부하 축약을 검증하기 위한 집단부하 구성방법에 관한 연구 (Grouping Method of Loads to Verify the Aggregation of Component Load Models)

  • 지평식;이종필;임재윤
    • 대한전기학회논문지:전력기술부문A
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    • 제50권4호
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    • pp.172-179
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    • 2001
  • A component based method out of load modeling is to aggregate component load model according to the composition rate of each component load at load bus based on the circuit theory. But the most of component loads respond complex nonlinear characteristics respect to voltage and frequency variation due to the control techniques and semiconductor elements applied to component load. It needs to verify this approach through actual experiment of the aggregation of component load even if it can be down. To identify this aggregation method well known, this paper is proposed the classifying method of component load characteristics for component loads to group by quantitative analysis. The component load characteristics were divided into several types by KSOM (kohonen self organizing map), which can classify multi-dimension vector, component load pattern, into two-dimension vector. Some ambiguous cases happened from KSOM were classified by the proposed closing degree.

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Aggregation of Measures of Effectiveness with Constant Sum Scaling Method and Multiple Regression

  • Kim, Hyung-Bae
    • 한국국방경영분석학회지
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    • 제5권2호
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    • pp.27-38
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    • 1979
  • This method explores a method of aggregating the measures of effectiveness of a weapon system from its characteristics. With this method, the constant sum method and multiple regression are used to develop a functional relationship between system effectiveness and system characteristics. As an example, a study of a tank weapon system was${\cdot}$conducted with data from the U.S. Army Armor School. It was concluded that the aggregation method is feasible, and that for the tank system studied, the reciprocals of system characteristics give a good estimating equation for measuring tank system effectiveness.

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On the Aggregation of Multi-dimensional Data using Data Cube and MDX

  • Ahn, Jeong-Yong;Kim, Seok-Ki
    • Journal of the Korean Data and Information Science Society
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    • 제14권1호
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    • pp.37-44
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    • 2003
  • One of the characteristics of both on-line analytical processing(OLAP) applications and decision support systems is to provide aggregated source data. The purpose of this study is to discuss on the aggregation of multi-dimensional data. In this paper, we (1) examine the SQL aggregate functions and the GROUP BY operator, (2) introduce the Data Cube and MDX, (3) present an example for the practical usage of the Data Cube and MDX using sample data.

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