• Korean Journal of Child Studies
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• v.30 no.6
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• pp.281-295
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• 2009

Representative services of the afterschool in Korea are After-Schools of the Ministry of Education, Science and Technology, Community Child Centers, After-school Child Care, and Youth After-school Academy of the Ministry of Health, Welfare and Family. Each service is distinguished with its own founded laws, subject children, specialists, principle management agent, a number of participants, and more. Research issues of afterschool are development of new afterschool programs, evaluatjon of the effectiveness of the afterschool, establishment of policies related to cooperative efforts among the different services of the afterschool, obtainment of legal status, and enhancement of the credential of its personnels. To guarantee the quality of the Afterschool and improve personnels' working conditions, various means are to be implemented. In regard to programatic and policy issues, the afterschool is needed to establish a system for training the afterschool coordinators and of its accreditation and to develop more child-centered afterschool programs. Also, it is needed to legislate fundamental law and consolidate communication system among the services of the Afterschool in pursue of their effective utilization and actual expansion.

• Korean Journal of Veterinary Research
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• v.29 no.3
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• pp.407-416
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• 1989

The prospect of live vaccines consisting of genetically modified vaccinia virus expressing foreign genes is exciting, but important issues concerning safety and efficacy need to resolved. Vaccinia virus (VV) is an efficient expression vector with broad host range infectivity and large DNA capacity. This vector has been particularly useful for identifying target antigens for humoral and cell-mediated immunity. The WHO smallpox eradication program, involving the extensive use of VV vaccines, resulted in the late 1970s in the elimination of one of the world's most feared diseases. This achievement is a triumph for preventive medicine and for international collaboration in public health. In 1980, WHO recommended that the routine use of smallpox vaccine should be stopped. Against this background, the prospect of li ve vaccines consisting of genetically modified VV expressing foreign antigens arising from the work of Moss, and Paoletti and their colleagues in 1982 has been greeted with enthusiasm. These investigators have shown that genes coding for immunogenic proteins can be inserted into VV DNA without impairing the ability of the virus to grow in cell culture. Moreover experimental animals infected with VV recombinants containing genes coding for a variety of immunizing proteins have been shown to be protected against challenge infection with the corresponding infectious agent. In this communication, I describe current progress in the construction of a novel plasmid vector that facilitate the insertion and expression of foreign genes in VV as well as the selection of recombinants.

• Journal of the Korean Society of Propulsion Engineers
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• v.20 no.5
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• pp.84-89
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• 2016

THPP(Titanium Hydride Potassium Perchlorate) is an igniter composed of potassium perchlorate as oxidizing agent and titanium hydride as fuel with a Viton binder. THPP is commonly found in the aerospace, defence and automotive industries. This research is investigeted for the manufacturing process and characteristics analysis of the THPP such as the performance and shape/calorimetry/pressure characteristics of the THPP on PMD(Pyrotechnic Mechanical Device). Also, THPP composite ratio is designed by CEA program.

• The Journal of Advanced Prosthodontics
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• v.5 no.4
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• pp.434-439
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• 2013

PURPOSE. The aim of the present study was to evaluate the effects of posts with different morphologies on stress distribution in an endodontically treated mandibular premolar by using finite element models (FEMs). MATERIALS AND METHODS. A mandibular premolar was modeled using the ANSYS software program. Two models were created to represent circular and oval fiber posts in this tooth model. An oblique force of 300 N was applied at an angle of $45^{\circ}$ to the occlusal plane and oriented toward the buccal side. von Mises stress was measured in three regions each for oval and circular fiber posts. RESULTS. FEM analysis showed that the von Mises stress of the circular fiber post (426.81 MPa) was greater than that of the oval fiber post (346.34 MPa). The maximum distribution of von Mises stress was in the luting agent in both groups. Additionally, von Mises stresses accumulated in the coronal third of root dentin, close to the post space in both groups. CONCLUSION. Oval fiber posts are preferable to circular fiber posts in oval-shaped canals given the stress distribution at the postdentin interface.

• Korean Chemical Engineering Research
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• v.54 no.6
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• pp.817-821
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• 2016

Levodopa or L-3,4-dihydroxyphenylalanine (L-DOPA) is the direct precursor of the neurotransmitter dopamine. L-DOPA is a well-known neuroprotective agent for the treatment of Parkinson's disease symptoms. L-DOPA was synthesized using the enzyme, tyrosinase, as a biocatalyst for the conversion of L-tyrosine to L-DOPA and an electrochemical method for reducing L-DOPAquinone, the product resulting from enzymatic synthesis, to L-DOPA. In this study, three electrode systems were used: A glassy carbon electrode (GCE) as working electrode, a platinum, and a Ag/AgCl electrode as auxiliary and reference electrodes, respectively. GCE has been modified using electropolymerization of pyrrole to facilitate the electron transfer process and immobilize tyrosinase. Optimum conditions for the electropolymerization modified electrode were a temperature of $30^{\circ}C$ and a pH of 7 producing L-DOPA concentration 0.315 mM. After 40 days, the relative activity of an enzyme for electropolymerization remained 38.6%, respectively.

• Korean journal of communication and information
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• v.80
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• pp.193-223
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• 2016

This study tried to examine the transfiguration process of cable broadcasting business in the early 1960s of Korea. Especially, on the basis of a critical mind of examining autonomy of cable broadcasting operator as agent, this paper examined not only the technical and financial business management, and the drawing up of a program, but also business plans of the National Cable Broadcasting Association in initial establishment time of 1960s.

• Korean Journal of Veterinary Research
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• v.50 no.2
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• pp.133-137
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• 2010

Rabies virus (family Rhabdoviridae, genus Lyssavirus, RV) is the causative agent of rabies in mammals. We conducted a sero-epidemiological survey for RV using sera from South Korean stray and companion dogs in the present study. A total of 533 canine serum samples were collected between February 2006 and December 2007 and were screened for rabies immunity with a neutralizing peroxidase linked assay. Both companion (49.1%) and stray (60.1%) dogs demonstrated RV seropositivity. Regional RV antibody prevalence was measured in the Jeju (87.5%), Gyeonggi (62%), Gyeongsang (59.1%), Jeonra (42%), Chungcheong (37.9%), and Gangwon (30.4%) provinces. Prevalence increased with age but did not exceed 80% in any age group. Stray and companion dogs had RV antibody prevalence values of 26.7% and 23.7%, respectively. Seroprevalence was significantly associated with age $({\chi}2\;=\;9.46;\;p\;=\;0.024)$ for companion dogs, although this association was not evident in stray dogs. There were no significant differences in age between stray and companion dogs and no gender differences in RV seroprevalence. Our results suggested that a widespread and reinforced vaccination program must be applied to Korean dogs.

• Journal of the Korean Society of Safety
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• v.24 no.3
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• pp.39-46
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• 2009

A recent and promising method for shear strengthening of reinforced concrete(RC) members is the use of near surface mounted(NSM) fiber reinforced polymer(FRP) reinforcement. In the NSM method, the reinforcement is embedded in grooves cut onto the surface of the member to be strengthened and filled with an appropriate binding agent such as epoxy paste or cement grout. This paper illustrates a research program on shear strengthening of RC beams with NSM channel-type FRP beams which is developed in this study. The objective of this study is to clarify the role of channel-type FRP beam embedded to the beam web for shear strengthening of reinforced concrete beams. Included in the study are effectiveness in terms of spacing and angle of channel-type FRP beams, strengthening method, and shear span ratio. the study also aims to understand the additional shear capacity due to glass fiber reinforced polymer beams and carbon reinforced polymer beams. And anther objective is to study the failure modes, shear strengthening effect on ultimate force and load deflection behavior of RC beams embedded with channel-type FRP beams on the shear region of the beams.

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2003.10a
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• pp.160-161
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• 2003

In Korea, 1, 357 tonnes of benzoyl peroxide was produced as a white granule with purities ranging 22 to 95％ in 2001. 75% of benzoyl peroxide is mainly used in the manufacture of expandable styrene polymer and other resins as initiators of polymerization and also been used in the treatment of acne vulgaris and the medical product contains mainly 5 to 10% of it. A very small portion of benzoyl Peroxide is used as flour bleaching agent, Potential human exposure from workplaces is expected to be negligible because this chemical is produced in closed system in only one company in Korea and when a production facility monitors its workplace for the worker exposure annually, the concentration of airborne aerosols at the personal sampling has been less than 1mg/㎥.

• Archives of Pharmacal Research
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• v.29 no.2
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• pp.165-171
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• 2006

Osteoarthritis is thought to be induced by the ageing-related loss of homeostatic balance between degeneration and repair mechanism around cartilage tissue in which inflammatory mediators such as reactive oxygen species, cytokines and prostaglandins are prone to overproduction under undesirable physiological conditions. Phlorotannins are unique polyphenolic compounds bearing dibenzo-1,4-dioxin skeleton which are not found in terrestrial plants but found only in some brown algal species such as Ecklonia and Eisenia families. Phlorotanninrich extracts of Ecklonia cava including LAD103 showed significant antioxidant activities such as DPPH radical scavenging, ferric ion reduction, peroxynitrite scavenging, and inhibition of LDL oxidation, indicating their possible antioxidative interference both in onset and downstream consequences of osteoarthritis. LAD103 also showed significant down regulation of $PGE_2$ generation in LPS-treated RAW 246.7 cells, and significant inhibition of human recombinant interleukin-$1{\alpha}$-induced proteoglycan degradation, indicating its beneficial involvement in pathophysiological consequences of osteoarthritis, the mechanism of which needs further investigation. Since LAD103 showed strong therapeutic potentials in arthritic treatment through several in vitro experiments, it is highly encouraged to perform further mechanistic and efficacy studies.