• The Korean Journal of Health Service Management
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• v.6 no.2
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• pp.201-209
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• 2012

This study was conducted to identify prevalence of sexual dysfunction and to determine factors influencing sexual dysfunction in middle aged women. The participants were 285 middle aged women. Data were collected through self-report questionnaires which were constructed to include general characteristics, FSFI (Female Sexual Function Index), sexual knowledge, sexual satisfaction. The mean score FSFI, sexual knowledge, sexual satisfaction were $14.82{\pm}5.74$, $11.25{\pm}2.67$, $45.84{\pm}8.60$, respectively. The score for sexual dysfunction showed significant difference age(F=3.52, p=.031) and health status(F=3.66, p=.013). Sexual dysfunction had significant positive correlation to sexual satisfaction(r=.46, p<001). Age and sexual satisfaction were significant predictor and accounted for 22% of the variance in sexual dysfunction middle aged women. Future sexual dysfunction management program for middle aged women should be considered their emotional, psychological, socio-environmental factors.

• The Korean Journal of Rehabilitation Nursing
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• v.20 no.1
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• pp.1-11
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• 2017

Purpose: This was a methodological study to develop a valid and reliable health assessment tool for middle-aged adults in long-term care settings (HATMAL). Methods: At the first stage of this study, initial 56-items HATMAL were derived via literature review, survey for needs assessment, and focus group interviews with experts. At the second stage, 54 items HATMAL were finalized via content validity test with 5 experts and a pilot study with 30 nurses. At the third stage, validity and reliability tests were conducted with 100 middle-aged patients in a long-term care hospital. Data were analyzed by factor analysis using SPSS 18.0 program. Results: Exploratory factor analysis resulted in 3 factors; functional assessment, symptom assessment, and comfort assessment. These 3 factors explained 83.8% of total variance and construct validity was confirmed. Test-retest reliability was .67 for appetite changes, .76 for regulating for behavior problems, and 1.0 for other items. Conclusion: Results indicate that HATMAL is valid and reliable to assess the health for middle-aged patients in long-term care settings. This study would contribute to provide more effective personalized treatment and care for middle-aged patients in long-term care settings considering their own characteristics.

• The Korean Journal of Physiology and Pharmacology
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• v.19 no.3
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• pp.269-274
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• 2015

Chronic inflammation has been proposed as one of the main molecular mechanisms of aging and age-related diseases. Although evidence in humans is limited, short-term calorie restriction (CR) has been shown to have anti-inflammatory effects in aged experimental animals. We reported on the long-term treatment of daumone, a synthetic pheromone secreted by Caenorhabditis elegans in an energy deficient environment, extends the life-span and attenuates liver injury in aged mice. The present study examined whether late onset short-term treatment of daumone exerts anti-inflammatory effects in the livers of aged mice. Daumone was administered orally at doses of 2 or 20 mg/kg/day for 5 weeks to 24-month-old male C57BL/6J mice. Increased liver macrophage infiltration and gene expression of proinflammatory cytokines in aged mice were significantly attenuated by daumone treatment, suggesting that short-term oral administration of daumone may have hepatoprotective effects. Daumone also dose-dependently suppressed tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$ )-induced nuclear factor-${\kappa}B$ (NF-${\kappa}B$) phosphorylation in HepG2 cells. The present data demonstrated that short-term treatment of daumone has anti-inflammatory effects in aged mouse livers possibly through suppression of NF-${\kappa}B$ signaling and suggest that daumone may become a lead compound targeting aging and age-associated diseases.

• Journal of Fisheries and Marine Sciences Education
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• v.24 no.6
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• pp.1027-1041
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• 2012

This study analyzed middle-aged woman volunteers' evaluations on their volunteering and its implications for the adult life-long education. The subjects were 126 women aged from 35 to 59 who enrolled in the volunteer centers in Busan, Korea. They participated in the survey of the volunteer effects and the factors that made them continue to volunteer. Survey said, middle-aged women volunteers perceived that they got positive feedback from others and themselves and it made them keep doing on volunteering. Based on their volunteering experiences, they reported the personal effects such as positivism, caring, volunteering capacity, industry, maturity and the family member's effects such as positivism and participating in their volunteering. They also mentioned that they had positive and negative effects on family relationship such as family relation reinforcement and being indifferent to their own family. Based on the research findings, it was the emphasized that supports for volunteering of the middle-aged women that helps them to accomplish the developmental tasks in the middle age are necessary. A scheme of linkage between volunteering and the adult life-long education was also dealt with. Finally, the implications on the further studies in the field were discussed.

• Korean Journal of Occupational Health Nursing
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• v.22 no.1
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• pp.47-56
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• 2013

Purpose: This study is to identify the factors that affect middle-aged workers' health promoting behaviors. Methods: 214 middle-aged workers participated in surveys, and the data were collected from August to September 2012 and analyzed by using descriptive statistics, Pearson's correlation coefficient, and multiple regression analysis with PASW 18.0 program. Results: It was found that among the factors, the degree of job stress (t=7.69, p<.001) and depression (t=6.23, p<.001) were significantly high for type D individuals, while non type D showed meaningful degree of self-related health status (t=-3.66, p<.001) and health promoting behaviors (t=-4.71, p<.001). The notable variable that affected the health promoting behaviors of the middle-aged workers was depression for both type D (${\beta}$=-.357, p= .029) and non type D (${\beta}$=-.325, p<.001) individuals, and this variable accounted for 24.1% and 18.2% respectively. Conclusion: The study revealed that the middle-aged workers showed high degree of job stress and depression that influenced on their health promoting behaviors. Thus, they are recommended to receive health management programs that offer treatment through consulting considering their individual personalities.

• Journal of Korean Clinical Health Science
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• v.4 no.4
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• pp.782-789
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• 2016

Purpose. The purpose of this study was to examine the related factors of quality of life (QOL) among middle-aged male. Method. The participants in this study were 144 middle aged male. Between October and November 2016, data were collected through questionnaires. Data analysis was performed using PASW (SPSS) 21.0 program, and one-way ANOVA, Pearson correlation coefficients, and stepwise multiple regression analysis. Results. The mean QOL of this study was 2.99/5. The significant correlates of QOL were family support (${\beta}=.21$, p=.024), health status (${\beta}=.24$, p=.003), workplace spirituality ${\beta}=.55$, p<.001), and these variables explained 55.9% of variance in QOL. Conclusion. The study suggests that family support workplace spirituality are an important factors in explaining QOL of the middle-aged male. Therefore, it is necessary to be considered family support and workplace spirituality for promoting life satisfaction of middle-aged male.

• Journal of Korean Academy of Nursing
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• v.35 no.7
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• pp.1248-1257
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• 2005

Purpose: This study was to examine the effects of an exercise program for middle-aged obese women. Method: The exercise program combined folk dance and resistance training. The subjects group consisted of 85 middle-aged obese women between 40 and 60 years of age. Three 8 week sessions consisted of a $55-80\%$ maximum heart rate (MHR) exercise for 60-90 minutes a day and 3 times a week from March to November, 2004. Data was collected through a pre- and post-exercise test before and after each session. Data was collected with Inbody, dynamometer and blood. This data was analyzed by descriptive statistics, and a paired t-test with an SPSS/PC(10.0 version) program. Results: There were significant positive changes in body weight, body fat mass, body mass index, percent body fat, muscle strength, muscle endurance, flexibility, and balance quality, but no significant positive changes in skeletal mass, fat free mass, percent abdominal fat(waist-hip ratio), visceral fat area, agility, total cholesterol, high density lipoprotein cholesterol, or triglycerides. Conclusion: This study showed that an exercise program has partially positive effects for middle-aged obese women. The results of this study show that exercise at community health centers should continue for middle-aged obese women's health.

• International Journal of Highway Engineering
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• v.18 no.2
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• pp.1-9
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• 2016

PURPOSES : The performance properties (indirect tensile strength, rutting resistance, and resilient modulus) of recycled aged CRM mixtures and their correlation with Superpave binder properties (viscosity, high failure temperature, $G^*sin{\delta}$, and stiffness) were investigated. METHODS: A series of Superpave binder tests was performed by using a rotational viscometer, DSR, and BBR to evaluate the performance properties. In addition, the CRM mixes were artificially aged through accelerated aging processes, and their properties were evaluated. The correlation between the properties of recycled aged CRM binders and the engineering properties of recycled aged CRM mixtures was experimentally determined. RESULTS : The rut depth values decreased and the ITS values increased with increasing high failure temperature. In general, the resilient modulus properties seemed to be poorly correlated with the high-temperature values, regardless of the aggregate source. CONCLUSIONS: The recycled aged CRM binders and mixtures can lead to satisfactory performance, and the properties of these binders are strongly correlated with the engineering properties of the mixtures.

• Korean Journal of Materials Research
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• v.29 no.3
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• pp.137-142
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• 2019

The microstructure, phase, and mechanical properties of three aged porcelain insulators which were manufactured in different years (1973, 1995 and 2008) and which were used in the field for different amounts of time, were investigated. With X-ray 3D computed tomography (CT), defects with ~mm size can be detected without destroying the aged insulators. Defects of small specimens, which are cut from the aged insulators and polished, are analyzed with optical and scanning electron microscopy (OM and SEM), and defects of um size are detected by OM and SEM. The number and size of defects in all the aged insulators are similar. Porcelain insulators manufactured in 1973 contain more $SiO_2$ (quartz and cristobalite) than those manufactured in 2008. Those manufactured in 2008 contain more $Al_2O_3$ than those manufactured earlier. The Vickers hardness of the insulator manufactured in 1973 has the lowest value. The formation of the cristobalite ($SiO_2$) in the insulator manufactured in 1973 which can come from the phase transformation of quartz can cause stress in the insulator by formation of microcracks, which can lead to the low hardness of the insulator.

• Journal of Animal Reproduction and Biotechnology
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• v.34 no.1
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• pp.35-39
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• 2019

This study aimed to recover the ovarian function through in vitro culture of preantral follicles from aged mice. First, we isolated the preantral follicles from ovaries of sixty-seven-week old B6D2F1 mice with decreased fecundity to know how many follicles were present in them, which was 6 preantral follicles including 2 primary, 2 early secondary and late secondary follicles from 8 aged mice. It was confirmed that a few follicles (~2) were present in aged mice through histological analysis compared to adult mice as control. The 9 days of in vitro culture of preantal follicles showed in vitro growth and induced maturation after treatment with hCG (2.5 IU/mL) and EGF (5 ng/mL). Cumulus cells in the cumulus-oocyte complexes (COCs) were removed using hyaluronidase and oocytes at the germinal vesicle (GV) and GV breakdown (GVBD) were obtained from preantral follicle culture of aged mice in vitro. In conclusion, these observations demonstrated that there still were a few preantral follicles in the ovaries of 67 week-old mice, which we were able to culture in vitro and oocytes were obtained from them. This study proposed an in vitro culture system using preantral follicle as a therapeutic strategy for fertility preservation in humans for assisted reproductive medicine.