• Journal of Nutrition and Health
• /
• v.48 no.6
• /
• pp.496-506
• /
• 2015

Purpose: The purpose of this study was to estimate dietary flavonoids intake of Korean adolescents. Methods: Using data from the 2007-2012 Korean National Health and Nutrition Examination Survey, a total of 3,957 subjects aged 12-18 were included in this study. We estimated individual daily intake of total flavonoid and six flavonoid classes including flavonols, flavones, flavanones, flavan-3-ols, anthocyanidins, and isoflavones by linking food consumption data with the flavonoids in the commonly consumed food database. The distribution of sociodemographic, health-related, and dietary factors according to flavonoids intake was examined. Results: Average dietary flavonoids intake of the study subjects was 195.6 mg/d in girls, and 189.4 mg/d in boys. The highest flavonoids intake group consumed significantly more fiber, vitamin C, legumes, fruits, and vegetables (p < 0.01) and less fat, grains, meats and dairy foods than other lower consumption groups (p < 0.001). Dietary flavonoid intake showed negative correlation with waist circumference and systolic blood pressure (p < 0.05). Conclusion: This study provided basic data for estimation of flavonoids intake of Korean adolescents. Further research will be required for analysis of the association of flavonoids intake and health-related factors such as cardiovascular risk factors.

• Journal of Nutrition and Health
• /
• v.48 no.6
• /
• pp.468-475
• /
• 2015

Purpose: Genetic polymorphisms in antioxidant defense and detoxification genes may modulate the levels of oxidative stress biomarkers. Methods: A total of 301 healthy preschool-aged children in the Seoul and Kyung-gi areas were recruited. DNA was extracted from blood for genotyping of manganese superoxide dismutase (Mn-SOD) Val16Ala, glutathione S-transferase (GST) P1 Ile105Val, GSTT1 present/null, and GSTM1 present/null polymorphisms by PCR-restriction fragment length polymorphism or multiplex PCR analyses. In addition to a questionnaire survey, the levels of urinary 8-hydroxyl-2-deoxiguanosine (8-OHdG) and plasma malondialdehyde (MDA) were measured by ELISA. Results: Significantly higher urinary 8-OHdG concentrations were observed in GSTP1 Ile/Val + Val/Val genotype (p = 0.030), and tended to be higher in Mn-SOD Val/Val genotype (p = 0.065). On the other hand, exposure to environmental tobacco smoking (ETS) and interaction between ETS and gene polymorphisms did not significantly influence either urinary 8-OHdG concentrations or serum MDA. Conclusion: Based on our findings, GSTP1 Ile/Val gene polymorphisms might modulate the levels of oxidative stress biomarkers in healthy preschool children.

• Journal of the Korean Institute of Landscape Architecture
• /
• v.40 no.6
• /
• pp.60-69
• /
• 2012

The project on Geonjisan Universal Design Forest Trail in Jeonju City was designed and constructed by an NGO called 'Jeonbuk Forest for Life' which was a winner for the '2008 Open Competition by the 'Committee for Greening Society' established in Korea Land Corporation. The purpose of this study is to evaluate the design satisfaction of UD forest trail. Post Occupancy Evaluation (POE) method was applied to measure the user satisfaction and the total number of users. The main result of the study were as follows: the major users of the Geonjisan UD forest trail were people aged over 60 years old(37%) and the main purpose of trail usage were to 'walk and rest'(51.5%) and to 'exercise and rehabilitation' (40.6%). Furthermore, the overall user rating for the UD forest trail design was "satisfied"(3.91 point in 5-point Likert Scale). The three most influencing factors of the overall user satisfaction were facility management, user conflict, and trail width and slope. About forty-five people were found to be End-user in the UD forest trail while six people were found as End-user in non-UD trails. Most importantly, the number of End-user observed on the UD forest trail was greater than the number found in non-UD forest trail. The result implies that the UD forest trail attracts more End-users and provides opportunity for gathering and interaction with the other users. Moreover, the satisfaction rate for the UD forest trail landscape is found to be high in Likert scale, which we can assume that the well-grown existing trees and topographic features as well as appropriately designed wood-paths influence the high satisfaction rate of the users. The POE of UD forest trail revealed the importance of universal design concept due to its convenient uses of the handicapped, old, weak, pregnant woman or children.

• Biomedical Science Letters
• /
• v.11 no.2
• /
• pp.185-192
• /
• 2005

Dietary chlarella has known as one of the best candidates for development of multifunctional probiotic foods owing to an excellent nutritional value such as high amount of proteins and various, valuable fatty acids. So many efforts were devoted to studying the chlorella as therapeutic agents or foods fighting against many diseases in the aged people such as cardiovascular diseases and cancers. In this study, we investigated sizes and weights of tumors derived from mice injected subcutaneously with tumorigenic cells to see if antitumor activity would be found in mice dieted with the chlarella complex. After BALB/c mice were dieted with $5\%$ organic cultured chlorella complex diet throughout for 19weeks, the fibrosarcoma was induced by subcutaneous injection of tumorigenic cells at the 3 weeks before sacrifice. The average weight of tumors in the diet group were significantly reduced to $60\%\;(P=0.012)$ of the one in control group, indicating that diet with the chlarella complex may have anticancer activity in mice. When the mice were dieted with $5\%$ organic cultured chlorella complex for 4 weeks before injecting the tumorigenic cells in order to see tumor-preventive effect of the diet, the potential preventive activity of the diet against cancer was implicated by the observation that the tumors were greatly reduced in the diet group to $37\%$ (P=0.l44) of the control group. Especially, when the $5\%$ diet were applied to mice after injecting with the tumorigenic cells, the tumors derived from the $5\%$ diet group were also decreased to $95\%$ (P=0.002) of those in the control group, suggesting that the diet with the organic cultured chlorella complex may also have therapeutic effect against tumor formation. As results, it was shown that the chlorella complex tested in this study had preventive and therapeutic effects on fighting against tumorigenesis. Therefore, the identification and further mechanistic study of the components which may be associated with antitumor activity from diet of the chlorella complex in the future will contribute to the development of anticancer probiotic foods, alternative therapeutic treatment against cancer, and a new anticancer drug.

• Biomedical Science Letters
• /
• v.3 no.1
• /
• pp.37-42
• /
• 1997

The concentrations in women's hair of essential and toxic elements such as Zn, Ni, Fe, Mn, Cu, Cr, Pb and Cd in residential and factory areas in Pusan were determined, and all the elements were detected from all the samples. It was apparent that employees working in factory areas in Pusan were exposed directly to the essential and toxic heavy matals. This is based on the fact that average concentrations of Ni, Fe, Mn, Cu, Cr, Pb, and Cd in hair samples from women aged 10 to 29 in factory area, who were considered to be main members among women employees, were much higher than those of residential areas. That is, the highest concentrations found in the hair samples taken from women 10 to 29 years old living in factory areas were 110 times higher in Cr (in the women in their 20's), 92 times higher in Pb (in the women in their teens) and 23 times higher in Cd (in the women in their 20's) than those living in residential areas. Furthermore, it was suggested that the heavy metals may be accumulated gradually in human bodies as humans get older, based on the fact that the concentrations of Cr, Pb, and Cd in women living in residential areas were higher in older age groups, although the average contents of these elements in residents from residential areas were similar with those of several foreign countries.

• Korean Journal of Biological Psychiatry
• /
• v.20 no.4
• /
• pp.151-158
• /
• 2013

Objectives To investigate the pattern of subclinical hypothyroidism (SCH) in patients with bipolar disorders managed by lithium or valproic acid. Methods The study participants were 106 patients with DSM-IV bipolar disorders receiving planned maintenance treatment at the Mood Disorders Clinic of Seoul National University Bundang Hospital (aged between 17 and 64, mean duration of follow-up = 875.65 days). Using the bipolar disorder registry, thyroid function data were analyzed to assess the frequency of and the risk factors for SCH in patients managed by lithium (n = 64) or valproic acid (n = 42) for more than 5 months. Results Overall frequencies of SCH were 20.3% (13/64) in the lithium group, 14.3% (6/42) in the valproic acid group, and between the two groups there is no difference (p = 0.43). No differences were observed in the potential risk factors for SCH between the two groups including age, sex, subtype of bipolar disorder, baseline TSH, and concomitant antipsychotic use. In cases with SCH, thyroid-stimulating hormone (TSH) showed a tendency to increase at 3 month after the initiation of lithium or valproic acid. A gradual increase in the number of patients showing SCH was found within the first 3 years of medication. Conclusions With regular monitoring and careful assessment, there was no difference in the risk of SCH between lithium and valproic acid maintenance. The risk of mood stabilizer-associated SCH may gradually increase within 3 years following the commencement of medication, thereby mandating close monitoring for the first 3 years of treatment. Further studies with large sample size would be needed to confirm these findings.

• Journal of the Korean Society of Costume
• /
• v.53 no.6
• /
• pp.145-159
• /
• 2003

The purpose of this study was to classify body type for ready-to-wear sizes. The subjects were 300 women ages of 18-24. they were measured direct anthropometry. The body types for sizing system were divided by Rohrer Index. KS drop value and ISO drop value. The results of this study were as follows. 1. By adapting the Rohrer Index. we classify 3 types from anthropometric measurements. The thin type covered 39.3%, the standard type 51.0% and the obesity type 18.7%. The characteristics of clusters were as follows. Thin type was characterized by tall. slender type and slim. The standard type was characterized by middle sized. The obesity type was characterized by short. fat type. and large bust. 2. By adapting the KS system drop value. we classify 3 types from anthropometric measurements. The H type(drop 0) covered 25.6%. the N type(drop 6) 65.2% and the A type(drop 12) 9.2%. Type H was slightly tall large bust. and curved from waist to hip. Type A was slightly thin. large hip and smaller bust than type N. Principal factor components were bust size. The height could be divided into three groups. The Petite(l50cm) covered 5.5%. the Regular(l60cm) 64.7% and the Tall(l70cm) 29.8%. Through the crosstab of height and body type. we extracted regular height by N type 46.2% the largest cell. The body type was the higher order of N type. H type and A type. The tall was the higher order of Regular. Tall and Petite. 3. By adapting the ISO system drop value. we classify 3 types from anthropometric measurements. The H type(drop 0) covered 15.0%. the M type(drop 6) 41.0% and the A type(drop 12) 44.0%. Type H was slightly short. slightly fat and large bust. Type A was slightly tall. slight thin than type M. The height could be divided into three groups. We adjust the height section after allow for height distribution. The Short(152cm) covered 12.8%. the Regular(160cm) 66.9% and the Long(168cm) 20.3%. Through the crosstab of height and body type, we extracted regular height by M type 29.3% the largest cell. The body type was the higher order of M type, A type and H type. The tall was the higher order of Regular, Long and short.

• Korean Journal of Materials Research
• /
• v.4 no.5
• /
• pp.524-534
• /
• 1994

The effects of transformation temperature and mechanical properties by thermal cycle of CuZnAl shape memory alloy with a small of misch metal and Zr contents were investigated. The addition of misch metal and Zr was very effective for reducing the grain size. After solution treatment, the specimens were post-quench aged or step quenched at $100^{\circ}C$ to $350^{\circ}C$ for variation of Rockwell hardness value. It was found that the Rockwell hareness value was very increased at $200^{\circ}C$ and $250^{\circ}C$. The fracture strength and ductility have been significantly increased with the increase of misch metal conten when tensile tested below $M_f$ temperature. Also, the fracture strength has been more increased in the case of post quench aging treatment than that of the as-quenching treatment. Aging of the $\beta$-phase decreases the $M_s$ temperature, but that of the martensite phase increases the $A_s$ temperature. The change in $A_s$ temperature with post-quench aging can be attributed to recovery of order in the $\beta$phase. The hystersis of transformation temperature ($A_s-M_s$) has an increasing tendency by thermal cycles.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.41 no.3
• /
• pp.430-435
• /
• 2012

This study was carried out to investigate the rheological effects of black garlic extracts on the bread dough. 0, 5, 10 and 15% of black garlic extracts were added in the bread flour. Falling number, RVA (Rapid visco analyser), farinograph and alveograph were analyzed. Falling number was lowered by increasing the amount of the extract added in the wheat flour. The pasting characteristics of the dough by RVA, value of pasting temperature, peak viscosity, holding strength, final viscosity, break down and set back were increased compared to the control. In the Farinograph analysis, the consistency and the water absorption ratio were elevated with the increase of the extract added. However, the rapid decrease of stability and the time to breakdown values were observed by increasing the extract addition amount compared to the control. However the mixing tolerance index (MTI) was rapidly increased as the amount of the extract addition was increased, and the highest farinogram quality number was observed in the control. Through the alveograph analysis, $P_{max}$ value was found to show the highest value in the control, while the L and G values were higher but W values was lowered in the dough with added 15% black garlic extract. As a result of the analysis, there was no significant bad effect until 5% of black garlic extracts was added to the bread dough.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.2
• /
• pp.649-656
• /
• 2016

This study was a retrospective examination to identify the association of postoperative delirium of the prognosis on following femur fracture surgery in elderly patients. Data was collected from the medical records of elderly patients (aged 65 years or older), who underwent femur fracture surgery from July 2010 to January 2014, following on 3-years in one university hospital. A total of 68 patients were involved. There were 31 cases (45.6%) with delirium and 37 cases (54.4%) without delirium. The participant's average age was 80.8 (patients with delirium), and 81.8 (delirium without patients) years of age, respectively, and most of them were female. There was no significant difference between the two groups. Taking five or more medications, serum creatinine level, and the total medical costs were significantly different in the delirium group and non-delirium group. In addition, the proportional hazard model of Cox to determine the predictors for the major clinical outcome occurring after surgery revealed delirium, five or more multi-drug use, and an experience of transfusion to be significant predictors. In conclusion, postoperative delirium in the elderly undergoing femur fracture surgery can have a negative clinical outcome in patients and caregivers. Therefore, a preoperative evaluation and management of the risk factors will be necessary.