• 대한정형도수물리치료학회지
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• 제19권1호
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• pp.9-20
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• 2013

Background: This study was conducted to provide preventive measure for the musculoskeletal disorders in automobile parts manufacturing workers. Method: The author surveyed to the musculoskeletal symptoms prevalence and its related factors from 10th to 17th April 2011 with structured self administered questionnaires. 223 out of 225 collected questionnaires were used for final analysis, excluding 2 questionnaires with no valid response. Based on the diagnostic criteria of NIOSH (National Institute for Occupational and Health), an investigation was made into the prevalence of musculoskeletal symptoms as well as into the factors related to individual items. Results: The prevalence of musculoskeletal symptoms according to the criteria of NIOSH was the highest in the shoulder (52.9%), followed by the neck (39.%), the hand/wrist (35%), the waist (29.6%), the arm/elbow (24.7%), and the leg/food (23.8%). One-way analysis showed that among general characteristics, age was the musculoskeletal risk factor with the greatest effect. Whereas among work-related characteristics, significant risk factor didn't find. Yet it was shown that among ergonomic work postures, high degree of musculoskeletal risk was shown by the posture involving frequent and repetitive movement of the arm and the hand/wrist and also by the posture involving standing for a long time. Multiple regression analysis showed that musculoskeletal risk was 1.795 times higher in those age 50 and over than in those under age 50; 1.67 times higher in the high risk stress group than in the low risk stress group; and 1.131 higher in the group involving the repetitive use of the hand/arm than in the other groups (p<.05). Conclusion: The prevalence and stress score of automobile parts manufacturing workers were higher than other occupation workers. Among general characteristics, drinking and smoking were shown to be related to stress score; while age was shown to have significant effect on musculoskeletal risk.

• 보건교육건강증진학회지
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• 제18권1호
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• pp.93-108
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• 2001

The purpose of this study was to identify the factors that affected to physical functions, activities of daily living (ADLs) and instrumental activities of daily living (IADLs). The subjects for this study, 236 persons, 65 years and over, who were living at rural area in Chun-Cheon city. This survey was carried out from march 3rd to April 25th, 1998. The data was analysed by using SPSS PC+ program. The results were as follows. 1.The variables that were related to the conditions of physical functions were as follows; age, sex, educational level among the general characteristics; raising ways of money, monthly using money for life, states of pocket money, obtaining method of pocket money, state of weight, problems in mind, whether or not chronic illness among socio ㆍeconoㆍphysical conditions; the level of satisfactions in life, subjective condition of health among the subjective thinking ; controlling state in smoking and drinking of alcohol among the lifestyles for promoting health. But the variables for medical utilization were not related to the level of physical function. 2. The variables that were associated with the condition of ADLs were as follows; age among the general characteristics; monthly using money for life, working amount among the socioㆍeconoㆍphysical conditions; subjective conditions of health among the subjective thinking. But The variables for medical utilization, lifestyle for promoting health were irrelevant to the conditions of ADLs. 3. The variables that were related to the conditions of IADLs were as follows; age, educational level among the general characteristics; raising ways of money, monthly using money for life, resident type in the household, procurement method of pocket money, level of weight, problems in mind, wether or not chronic illness among socioㆍeconoㆍphysical condition; regularity of health checking among lifestyles for promoting health; kinds of utilizing medical agent among the variables about utilization patterns of medical agencies; subjective condition of health among the subjective thinking In this study, in the aged there were related factors of physical and life functions, were age, working amount, subjective condition of health.

• 한국학교ㆍ지역보건교육학회지
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• 제19권3호
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• pp.15-27
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• 2018

Objectives: This study aims to investigate the estimated proportion for influenza vaccination and to identify factors associated with influenza vaccination in Korean adults aged 50 and older with asthma. Methods: Data from 2010-2015 Community Health Survey(n=23,662) was used. A chi-square test was performed to investigate the estimated proportion for influenza vaccination, and a multiple logistic regression analysis was used to identify the factors associated with self-reported influenza vaccination. Results: In men, 42.3-49.5% of asthma patients 50-64 years of age, and 78.5-90.2% of elderly (over 65 years of age) asthma patients received influenza vaccination. In women, 49.7-61.9% of asthma patients 50-64 years of age, and 82.7-89.7% of elderly asthma patients received influenza vaccination(p<0.0001). Low education level, non-smoking, non-drinking, hypertension, diabetes and use of public center were related to high influenza vaccination in 50-64 years old men with asthma. Low education level, non-smoking, bad health status, hypertension, diabetes and use of public center were related to high influenza vaccination in 50-64 years old women with asthma. Non-smoking and use of public center were related to high influenza vaccination in over 65 years old men with asthma. White-collar jobs, smoking, absence of hypertension and use of public center were related to low influenza vaccination in over 65 years old women with asthma. Conclusions: Influenza vaccination remains relatively low in asthma patients 50-64 years of age. It is necessary to recommend vaccination to asthma patients, provide them with information, and devise other strategies to improve vaccination.

• BMB Reports
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• 제49권11호
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• pp.641-650
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• 2016

Cellular senescence is a process by which cells enter a state of permanent cell cycle arrest. It is commonly believed to underlie organismal aging and age-associated diseases. However, the mechanism by which cellular senescence contributes to aging and age-associated pathologies remains unclear. Recent studies showed that senescent cells exert detrimental effects on the tissue microenvironment, generating pathological facilitators or aggravators. The most significant environmental effector resulting from senescent cells is the senescence-associated secretory phenotype (SASP), which is constituted by a strikingly increased expression and secretion of diverse pro-inflammatory cytokines. Careful investigation into the components of SASPs and their mechanism of action, may improve our understanding of the pathological backgrounds of age-associated diseases. In this review, we focus on the differential expression of SASP-related genes, in addition to SASP components, during the progress of senescence. We also provide a perspective on the possible action mechanisms of SASP components, and potential contributions of SASP-expressing senescent cells, to age-associated pathologies.

• 한국보건간호학회지
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• 제28권3호
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• pp.419-431
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• 2014

Purpose: The aim of this study was to understand the determinants of health-related quality of life (HRQOL) according to age groups in vulnerable elderly women. Methods: We conducted a cross-sectional study with 1,533 elderly women beneficiaries of the visiting health care program in Seoul. The participants were divided into three age groups: the young-old (n=753, 65-74 years), old-old (n=602, 75-84 years), and oldest-old (n=178, 85 years or older) groups. HRQOL was measured using the SF-8 questionnaire. Results: HRQOL was found to be worse in the oldest-old group (p=.007). Factors associated with HRQOL differ by age groups. In the young-old and old-old groups, higher HRQOL showed significant correlation with a higher level of self-rated health (SRH) and a lower level of depression, instrumental activities of daily living (IADL) dependence, and the number of chronic diseases. In addition, higher HRQOL was observed for elderly living alone than for those living with family. In the oldest group, higher HRQOL showed significant correlation with a lower level of depression, activities of daily living (ADL) dependence, and a higher level of SRH. Conclusions: In age specific groups, lower levels of HRQOL were observed for the oldest-old group than for the other age groups. Age group-specific nursing strategies may be required for improving HRQOL levels of vulnerable elderly women.

• 한국의류학회지
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• 제20권1호
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• pp.28-42
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• 1996

The purposes of this sturfy were 1) to examine the difference between cognitive and actual age, 2) to understand apparel shopping orientations and the importance of store attributes related to cognitive age and 3) to identify relationship.; between apparel shopping orientations and importance of store attribute, ; in cognitively younger and older groups For the study, questionnaires were administered to 450 elderly women over 55 years of age. The questionnaires were designed to mea, ;ore apparel shopping orientations (hedonic, store loyal and brand conscious, careful and planned, confidented and independent, and economic shopping), importance of store attributes, cognitive age and demographics. Using a base of 204 women, data was analyzed by using descriptive statistics, t-test and correlation coeffictents. The results of this study weve summarized as follows. 1. The older women saw themselves on average 6. 6 years younger than they really were 77.6% of the respondents blieved themselves to be cognitively younger 2 Cognitively younger women were more hedonic and less carefull and planned than cognitively older women in apparel Shopping. 3. Cognitively older women thought that proximity and private dressing rooms in apparel stores were mote important attributes than cognitively younger women. In terms of apparel store attributes, older consumers placed importances on product quality, fit and size, design suited to their age, attractive price, and the availability to return unsatisfactory products, in orders.

• 대한물리의학회지
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• 제9권3호
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• pp.301-305
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• 2014

PURPOSE: The purpose of this study was to determine the optimal thresholds of serum lipid level related to hypertension according to age in Korean adults. METHODS: In total, 564 adults who visited the health examine center in general hospital were included. The blood pressure and lipid profiles of low density lipoprotein cholesterol(LDL), high density lipoprotein cholesterol (HDL), triglyceride(TG) were measured. Receiver operating characteristic (ROC) curve were used to establish optimal thresholds between blood pressure and lipid profiles. RESULTS: The optimal TG cutoff value were 110.50(mg/dl) in the 18-39 and 81.50(mg/dl) in the 40-59 age group, and optimal cutoff value of LDL were 126.50(mg/dl) in the 40-59 age group and 111.00(mg/dl) in the 60 and over age group. There was a negative correlation between HDL and hypertension, a higher HDL decreased hypertension. The optimal cutoff value of HDL was 49.50(mg/dl) in the 18-39 age group. CONCLUSION: The thresholds of hypertension were lower in LDL and TG with aging. This result indicated that elderly people needs to concern more about their lipid profiles to maintain healthy cardiovascular function.

• BMB Reports
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• 제48권10호
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• pp.549-558
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• 2015

Cellular senescence is a process by which cells enter a state of permanent cell cycle arrest. It is commonly believed to underlie organismal aging and age-associated diseases. However, the mechanism by which cellular senescence contributes to aging and age-associated pathologies remains unclear. Recent studies showed that senescent cells exert detrimental effects on the tissue microenvironment, generating pathological facilitators or aggravators. The most significant environmental effector resulting from senescent cells is the senescence-associated secretory phenotype (SASP), which is constituted by a strikingly increased expression and secretion of diverse pro-inflammatory cytokines. Careful investigation into the components of SASPs and their mechanism of action, may improve our understanding of the pathological backgrounds of age-associated diseases. In this review, we focus on the differential expression of SASP-related genes, in addition to SASP components, during the progress of senescence. We also provide a perspective on the possible action mechanisms of SASP components, and potential contributions of SASP-expressing senescent cells, to age-associated pathologies.

• Korean Journal of Radiology
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• 제22권7호
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• pp.1194-1202
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• 2021

Objective: To investigate the age-dependent changes in regional cerebral blood flow (CBF) in healthy adults by fitting mathematical models to imaging data. Materials and Methods: In this prospective study, 90 healthy adults underwent pseudo-continuous arterial spin labeling imaging of the brain. Regional CBF values were extracted from the arterial spin labeling images of each subject. Multivariable regression with the Akaike information criterion, link test, and F test (Ramsey's regression equation specification error test) was performed for 7 models in every brain region to determine the best mathematical model for fitting the relationship between CBF and age. Results: Of all 87 brain regions, 68 brain regions were best fitted by cubic models, 9 brain regions were best fitted by quadratic models, and 10 brain regions were best fitted by linear models. In most brain regions (global gray matter and the other 65 brain regions), CBF decreased nonlinearly with aging, and the rate of CBF reduction decreased with aging, gradually approaching 0 after approximately 60. CBF in some regions of the frontal, parietal, and occipital lobes increased nonlinearly with aging before age 30, approximately, and decreased nonlinearly with aging for the rest of life. Conclusion: In adults, the age-related perfusion patterns in most brain regions were best fitted by the cubic models, and age-dependent CBF changes were nonlinear.

• Advances in pediatric surgery
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• 제15권2호
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• pp.121-131
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• 2009

Intestinal malrotation presents with different clinical characteristics, depending upon the age of the patient. The medical records of 44 patients treated for intestinal malrotation with/without midgut volvuls between January 2002 and August 2009 at Seoul National University Children's Hospital were reviewed retrospectively. Patients were grouped by the age criteria of 1 and 12 months. Fourteen patients were under 1 month of age (31.8 %), 9 patients between 1 month and 12 months (20.5 %) and 21 patients over 12 months (47.7 %). Twenty patients (45.5 %) presented with volvulus. Vomiting (66 %) and abdominal pain (20 %) were the most common symptoms. UGIS (68.2 %) was the most frequent diagnostic tool. Mean postoperative hospital stay was 13.7 days. There were 7 mild postoperative complications. Volvulus was more frequent in patients under 1 month (p=0.025) than over 1 month. The interval between diagnosis and operation was shorter in patients under 1 month (p=0.003) than in patients over one month of age. In the age between under and over 12 months, volvulus was more common in those under 12 months of age, but the difference was not significant. The interval from diagnosis to operation was shorter in patients under 12 months than over 12 months of age (p=0.001). Vomiting was the most frequent symptom in patients under 12 months. On the other hand, abdominal pain was the most frequent symptom in patients over 12 months. In conclusion, patients with intestinal malrotation had age-related differences in the presence of midgut volvulus, the interval between diagnosis and operation, and clinical symptoms. The age of the patient should be considered in order to determine adequate treatment of malrotation.