• Title/Summary/Keyword: Age-Integration

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Manipulation of Tissue Energy Metabolism in Meat-Producing Ruminants - Review -

  • Hocquette, J.F.;Ortigues-Marty, Isabelle;Vermorel, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.5
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    • pp.720-732
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    • 2001
  • Skeletal muscle is of major economic importance since it is finally converted to meat for consumers. The increase in meat production with low costs of production may be achieved by optimizing muscle growth, whereas a high meat quality requires, among other factors, the optimization of intramuscular glycogen and fat stores. Thus, research in energy metabolism aims at controling muscle metabolism, but also liver and adipose tissue metabolism in order to optimize energy partitioning in favour of muscles. Liver is characterized by high anabolic and catabolic rates. Metabolic enzymes are regulated by nutrients through short-term regulation of their activities and long-term regulation of expression of their genes. Consequences of liver metabolic regulation on energy supply to muscles may affect protein deposition (and hence growth) as well as intramuscular energy stores. Adipose tissues are important body reserves of triglycerides, which result from the balance between lipogenesis and lipolysis. Both processes depend on the feeding level and on the nature of nutrients, which indirectly affect energy delivery to muscles. In muscles, the regulation of rate-limiting nutrient transporters, of metabolic enzyme activities and of ATP production, as well as the interactions between nutrients affect free energy availability for muscle growth and modify muscle metabolic characteristics which determine meat quality. The growth of tissues and organs, the number and the characteristics of muscle fibers depend, for a great part, on early events during the fetal life. They include variations in quantitative and qualitative nutrient supply to the fetus, and hence in maternal nutrition. During the postnatal life, muscle growth and characteristics are affected by the age and the genetic type of the animals, the feeding level and the diet composition. The latter determines the nature of available nutrients and the rate of nutrient delivery to tissues, thereby regulating metabolism. Physical activity at pasture also favours the orientation of muscle metabolism, towards the oxidative type. Consequently, breeding systems may be of a great importance during the postnatal life. Research is now directed towards the determination of individual tissue and organ energy requirements, a better knowledge of nutrient partitioning between and within organs and tissues. The discovery of new molecules (e. g. leptin), of new molecular mechanisms and of more powerful techniques (DNA chips) will help to achieve these objectives. The integration of the different levels of knowledge will finally allow scientists to formulate new types of diets adapted to sustain a production of high quality meat with lower costs of production.

Reversibility and safety of KISS1 metastasis suppressor gene vaccine in immunocastration of ram lambs

  • Han, Yan-Guo;Liu, Gui-Qiong;Jiang, Xun-Ping;Xiang, Xing-Long;Huang, Yong-Fu;Nie, Bin;Zhao, Jia-Yu;Nabeel, Ijaz;Tesema, Birhanu
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.6
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    • pp.835-841
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    • 2018
  • Objective: The aim of this study was to investigate the reversibility and safety of KISS1 metastasis suppressor (KISS1) gene vaccine in immunocastration. Methods: Six eight-week old ram lambs were randomly divided into vaccinated and control groups. The vaccine (1 mg/ram lamb) was injected at weeks 0, 3, and 6 of the study. Blood samples were collected from the jugular vein before primary immunization and at weeks 2, 4, 6, 10, 14, 22, and 30 after primary immunization. All ram lambs were slaughtered at 38 weeks of age, and samples were collected. Results: The specific anti-KISS1 antibody titers in vaccinated animals were significantly higher and the serum testosterone level was significantly lower than those in the control groups from week 4 to 14 after primary immunization (p<0.05). No significant difference was observed at weeks 22 and 30 after the primary immunization. Similar results were also found for scrotal circumference, testicular weight, length, breadth, and spermatogenesis in seminiferous tubules in week 30 after primary immunization. KS (KISS1-hepatitis B surface antigen S) fusion fragment of KISS1 gene vaccine was not detected in host cell genomic DNA of 9 tissues of the vaccinated ram lambs by polymerase chain reaction. Conclusion: The effects of KISS1 gene vaccine in immunocastration were reversible and no integration events were recorded.

A Study on Influential Factors for the Economic Activities of People with Disabilities (장애인의 경제활동에 미치는 영향요인 연구)

  • Lee, Jeong Seo;Kim, Hyun Deok
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.8 no.1
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    • pp.235-242
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    • 2013
  • For people with disabilities, getting a job makes it possible to advocate their own human rights, to improve their self-esteem and self-efficacy, to narrow economic, psychological and social divide between them and those without disabilities and ultimately to attain social integration. According to recent statistical data, there was an increase in the weight of people with disabilities, but their economic activities were on the wane, and it's required to explore what curbs the employment of people with disabilities to find feasible solutions. The purpose of this study was to examine influential factors for the economic activities of people with disabilities. The subjects in this study were the selected people with disabilities in the metropolitan area, on whom a survey was conducted to make an empirical analysis. The findings of the study were as follows: The people with disabilities engaged in less economic activities when they were basic livelihood security recipients, when they were older, and when they were female. And those who underwent job training and who were certified technicians were more likely to participate in economic activities. Therefore differentiated policy setting is required to boost the economic activities of people with disabilities after their general characteristics, characteristics as human resources and characteristics related to vocational training are carefully analyzed. As for general characteristics, whether they are basic livelihood security recipients or not should be considered to assess the degree of their poverty, and their gender, age and presence or absence of spouses should all be taken into account. In terms of vocational training, their certificates and job training experience should be investigated.

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Utilization Patterns and Determinants of Oriental Medical Services : Focused on the Residents of Taegu City (한방의료의 이용행태 및 이용결정요인 분석 - 일부 대도시 지역주민을 중심으로 -)

  • Yoo Wang-Keun;Ryu Kyung-A
    • Journal of Society of Preventive Korean Medicine
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    • v.4 no.2
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    • pp.1-24
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    • 2000
  • This study was conducted to examine utilization patterns and determinants of oriental medical services. Data were collected from 545 residents in Taegu city The results of this study are summarized as follows 1) 37.8% of subjects used oriental medical services in the past year. Especially, the female, the ages of 50 and 60 over, the single. low-educated. high-income class, white-collar class, medical insured tended to use more oriental medical services than another groups. 2) 46.7% of users of oriental medical services reported that number of visits in the past year was 2 - 5 times 37 1% of them was 1 times, and 4.5% over 10 times. 3) According to the reasons to choose the oriental medical facilities, most was 'on their own judgement'(48.8%) and 'by the advice of relatives and friends'(42.0%) Regarding to the objectives of using oriental medicine, 68.3% was 'treatment', 31.7% 'health counselling and promotion'. And among diseases of users, diseases of musculo-skeletal system was the highest(54.5%). 4) 57.9% of oriental medical services users had experience of utilizing western medicine on the same diseases. Among peoples with experiencing western medicine on the same diseases. 54.4% received oriental medical services 'in addition to western medicine', 45.6%'in place of western medicine 'And 41.2% of using both services reported that they had difficulty in deciding to choose the type of services -oriental medical services or western medicine-for their diseases. 37.3% of them answered that 'providing relevant information' was the most desirable measure to solve this problem, 27.3% 'establishment of effective referral system between oriental and western medical facilities '23.6% 'cooperative medical treatment systems in the same facilities', 11.8%'integration of oriental medicine into western medicine 5) According to the satisfaction level with each items of oriental medical services, the respondents had positive views on efficacy, kindness, and side-effects. They, however, had negative view on the cost of oriental medical services. 6) In regarding to the priority of improvement of oriental medical system,'expansion of insurance benefit package 'ranked first. 'expansion of insurance benefit Package 'ranked second, 'improvement of scientific methods and diagnostic technique 'third, and 'safety of herbal medicine' fourth in order. 7) The significant factors influencing the utilization of oriental medical services were kindness of oriental medical practitioners, efficacy , travel time, age To be brief, utilization rate of oriental medical services in urban area generally tends to be high. There, however, have been various barriers to limit oriental medical services, such as incomplete benefit package of oriental medical insurance and lack of coordination and referral system between oriental and western medical services, lack of scientific diagnostic procedures, high price etc . For the development of oriental medical services, Much attention to remove these limiting factors should be placed. In addition, kindness of oriental medical practitioners , which is expected to be more important factor in the consumer - focused health care environment than ever, should be kept high consistently. Since this study was conducted for specific residents of an urban city. further research including more sampling in different urban areas should be required to generalize the results of the study.

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A Study of Production Technology of Digital Contents upon the Platform Integration : Focusing on Cross - Platform Game (플랫폼 통합에 따른 디지털콘텐츠 제작기술 경향연구 : 크로스 플랫폼게임(Cross-Platform Game) 사례를 중심으로)

  • Han, Chang-Wan
    • Cartoon and Animation Studies
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    • s.14
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    • pp.151-164
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    • 2008
  • Cross platform game has brought about the expansion of game market, which results in technology innovation overcoming the limit of game consumption. The new model integrates both off and online game services. Gamers can now enjoy game service regardless of age, time, and space. If the technology evolution model of digital contents like cross-platform game engine can provide contents for several platform at the same time, the interactive service can be utilized into maximum level. It is also necessary to allocate, switch data as well as to innovate the transmission technology of data according to each platform. Providing the same contents for several platform as many as possible can be the most suitable strategy to enhance the efficiency and profits. However if the interactive service can be accomplished completely, the development of data switching technology and distribution should be made. To be a leader in the next digital contents market, one should develop the network engine technology which can embody the optimization of consumption in the interactive network service.

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Availability of Mobile Art in Smartphone Environment of Augmented Reality Content Industrial Technology (증강현실 콘텐츠 산업기술의 스마트폰 환경 모바일 아트 활용 가능성)

  • Kim, Hee-Young;Shin, Chang-Ok
    • The Journal of the Korea Contents Association
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    • v.13 no.5
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    • pp.48-57
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    • 2013
  • Smartphones provide users with environment for communication and sharing information and at the same time play an important role of mobile technology and mobile art development. Smartphone technology-related researches are being accelerated especially with the advent of mobile Augmented Reality(AR) age, but the studies on user participation that is essential for AR content industry were insufficient. In that regard, the assistance from mobile art area that has already developed these characteristics is essential. Thus, this article is to classify mobile art that has not been studied a lot domestically into feature phone usage and smartphone usage and to analyze each example case with the three most used methods. The usage of feature phones which use the sound and images of mobile devices can be divided into three: installation and performing methods, single channel video art method and five senses communication method. On the other hand, the usage of smartphones that use sensors, cameras, GPS and AR can be divided into location-based AR, marker-based AR and markerless AR. Also, as a result of examining mobile AR content utilization technology by industries, combined methods are utilized; tourism and game-related industries use location-based AR, education and medicine-related industries use marker-based AR, and shopping-related industries use markerless AR. The development of AR content industry is expected to be accelerated with mobile art that makes use of combined technology method and constant communication method through active participation of users. The future development direction of mobile AR industry is predicted to have minimized HMD, integration of hologram technology and artificial intelligence and make the most of big data and social network so that we could overcome the technological limitation of AR.

Sociological Understandings of Elderly Suicide and Its Primary Prevention (노인자살의 이해와 일차적 예방)

  • 김형수
    • Korea journal of population studies
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    • v.23 no.2
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    • pp.167-187
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    • 2000
  • The rates and numbers of elderly suicide in Korea have been increased during 1985-1998. This indicates the seriousness of the problems which the elderly are faced with. So many late-life problems may push older people across the edges. Those in unbearable situations may call out fur helps, they may try to cope with various ways, or they may commit suicides. Because it is widely believed that suicide among the elderly can be understood as a personal solution or alternative to late-life problems in old age, the elderly\`s suicides seem to be an appropriate indicator in estimating seriousness of late-life problems. A comparison of the history of suicide research with other populations shows that the several late-life problems have been found with placing an individual elder at risks for increasing suicidal behaviors Research has identified such problems as financial insecurity, retirement, loss of social roles, physical illness, lack of social supports, and loneliness as the problems that increase the incidence of suicidal behavior. Though it is difficult far us to explain and understand the phenomenon of the elderly\`s suicide because of its complexity, we need to ascertain problems and social conditions behind suicides and also to prepare for some appropriate policy-tasks in light of social welfare for the aged, through examining the phenomenon. For explaining the elderly\`s suicide, the theoretical orientations are based on sociological perspectives in the paper. From the standpoints of social integration theory and exchange theory, this study is to examine the relationship between late-life problems and suicide. These two may have been fruitfully employed in conjunction with each other. Finally, this study would identify urgent late-life problems related with the elderly\`s suicide and suggest the relevant policies for Korean elders. Sometime in the near future, the government should be required to provide social welfare programs for the elderly, particularly for those at risk for increasing suicidal behaviors.

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A Study on Factors Affecting Reemployment of the Disabled Workers owing to Industrial Injury in Korea (산재장애인의 재취업실태와 영향요인 분석)

  • Park, Soo-Kyeong
    • Korean Journal of Social Welfare
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    • v.37
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    • pp.171-193
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    • 1999
  • The ultimate goal of rehabilitation is social integration. Reemployment is, for the disabled workers, the primary source of not only income, but also identity and interaction. Unfortunately, for most disabled workers employment represents only a yet-to-be-fulfilled hope, a close but inaccessible goal, a daily reminder that they are not among the majority. The purpose of this study is to estimate reemployment rate in the industrial injured and to find factors affecting reemployment of disabled workers owing to industrial injury, and to make policy implication for the better industrial injury compensation rehabilitation system. The data were obtained through telephone interview with disabled worker who completed work injury compensation process in 1996-1997. The final sample was consisted of 1,060 respondents. The major findings were that almost lout of 3 disabled worker returned to work, and that the factor affecting reemployment of the disabled workers were severity injury, ADL(activity of Daily Living), the perception of disability severity, controlling for the demographic factors such as sex, age, education, marital status. The results indicated that psychosocial factors as well as physical function had influces on returning to work. The current findings suggests that rehabilitation services and policy aimed at enhancing vocational rehabilitation program and rehabilitation engineering services, and improving psychosocial resources should be considered by rehabilitation professionals and policy makers.

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Surveillance Evaluation of the National Cancer Registry in Sabah, Malaysia

  • Jeffree, Saffree Mohammad;Mihat, Omar;Lukman, Khamisah Awang;Ibrahim, Mohd Yusof;Kamaludin, Fadzilah;Hassan, Mohd Rohaizat;Kaur, Nirmal;Myint, Than
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.7
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    • pp.3123-3129
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    • 2016
  • Background: Cancer is the fourth leading cause of death in Sabah Malaysia with a reported age-standardized incidence rate was 104.9 per 100,000 in 2007. The incidence rate depends on non-mandatory notification in the registry. Under-reporting will provide the false picture of cancer control program effectiveness. The present study was to evaluate the performance of the cancer registry system in terms of representativeness, data quality, simplicity, acceptability and timeliness and provision of recommendations for improvement. Materials and Methods: The evaluation was conducted among key informants in the National Cancer Registry (NCR) and reporting facilities from Feb-May 2012 and was based on US CDC guidelines. Representativeness was assessed by matching cancer case in the Health Information System (HIS) and state pathology records with those in NCR. Data quality was measured through case finding and re-abstracting of medical records by independent auditors. The re-abstracting portion comprised 15 data items. Self-administered questionnaires were used to assess simplicity and acceptability. Timeliness was measured from date of diagnosis to date of notification received and data dissemination. Results: Of 4613 cancer cases reported in HIS, 83.3% were matched with cancer registry. In the state pathology centre, 99.8% was notified to registry. Duplication of notification was 3%. Data completeness calculated for 104 samples was 63.4%. Registrars perceived simplicity in coding diagnosis as moderate. Notification process was moderately acceptable. Median duration of interval 1 was 5.7 months. Conclusions: The performances of registry's attributes are fairly positive in terms of simplicity, case reporting sensitivity, and predictive value positive. It is moderately acceptable, data completeness and inflexible. The usefulness of registry is the area of concern to achieve registry objectives. Timeliness of reporting is within international standard, whereas timeliness to data dissemination was longer up to 4 years. Integration between existing HIS and national registration department will improve data quality.

A Study on the Evaluation of Biotope Preservation Value in District Unit - Case Study in Sinseo-Dong, Daegu - (지구단위 차원에서의 비오톱 보전가치평가 연구 - 대구광역시 신서동 택지개발 사업지구를 사례로 -)

  • Cho, Hyun-Ju;Ra, Jung-Hwa;Park, In-Hwan;Kim, Soo-Bong;Ryu, Yeon-Su;Jang, Gab-Sue
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.11 no.5
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    • pp.38-59
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    • 2008
  • This research has a meaning to provide basic data for eco-friendly way of district unit plans and ecological landscape planning by evaluation of biotope preservation value at the level of district unit and designating land development of the site, the whole area of Sinseo-dong (Dong-gu, Daegu metropolitan city) for research site. The summary of analysis result is as follows. As a result of classification of biotope types on the research site, it is divided into 11 biotope groups such as a residential biotope group and 51 specific biotope types which is subordinate to the groups. As a result of the first value assessment on classified biotope types, there are 16 types of natural rivers which is full of vegetation as a I class. Also it is analysed as 9 types of IIclass, 14 of IIIclass, 8 of IVclass, and 4 of Vclass. In particular, in light of a wildlife habitat, EB, in case of broad-leaved tree of mixed forest assessed as a II class, was classified into Iclass which is one-step upgraded as a final class with the analysis as there is a structural characteristic (more than 71% of low density, 50 years of age-class). As a result of second assessment, it is analysed that there are 17 special sites (1a,1b) and 33 special sites (2a, 2b, 2c) respectively for preservation of species and biotope. Particularly, in case of the No. 27 space, it was assessed that it has the value of about medium (IIIclass) level, but its value was upgraded with the on-spot detailed investigation that most of Aristolochia contorta, designated as a rare plant by Ministry of Environment, is growing. It is regarded that the above-mentioned research result on evaluation of biotope preservation value is expected to provide very important basic materials for future district unit plans and smooth integration with landscape ecology plans and eco-friendly space development.