• 전기학회논문지
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• 제65권2호
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• pp.349-353
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• 2016

The purpose of this study was to investigate possible age differences in the attenuation of acceleration in the upper body (from pelvis through shoulder to head) during fast walking. Thirty young and 29 elderly subjects participated in this study. Wireless acceleration sensors were attached on head, shoulder, and pelvis. Subjects performed two trials of fast walking on a treadmill, where the fast speed was defined as 1.5 times of the comfortable speed. Root-mean-squared (RMS) accelerations of each axis were compared with age group and sensor position as independent factors. In the AP direction, the pelvis acceleration was greater in the young and the shoulder-to-head attenuation was also greater in the young (p<0.001), so that the head acceleration was comparable between age groups (p=0.581). In the ML direction, the pelvis acceleration was greater in the young and also the pelvis-to-shoulder attenuation was greater in the young (p<0.001), so that the head acceleration was greater in the elderly group (p<0.001). Insufficient attenuation ML acceleration in the elderly resulting in the greater acceleration in the head may deteriorate the balance control which utilize feedback signals from the sensory organs in head, e.g., vestibular and visual systems.

• 한국운동역학회지
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• 제26권3호
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• pp.273-284
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• 2016

Objective: The purpose of this study was to investigate effects of upper limb, trunk, and pelvis kinematic variables on the velocity of Apkubi Momtong Baro Jireugi in Taekwondo. Method: Twenty Taekwondo Poomsae athletes (age: $20.8{\pm}2.2years$, height: $171.5{\pm}7.0cm$, body weight: $66.2{\pm}8.0kg$) participated in this study. The variables were upper limb velocity and acceleration; trunk angle, angular velocity, and angular acceleration; pelvis angle, angular velocity, and angular acceleration; and waist angle, angular velocity, and angular acceleration. Pearson's correlation coefficient was calculated for Jireugi velocity and kinematic variables; multiple regression analysis was performed to investigate influence on Jireugi velocity. Results: Angular trunk acceleration and linear upper arm punching acceleration had significant effects on Jireugi velocity (p<.05). Conclusion: We affirmed that angular trunk acceleration and linear upper arm punching acceleration increase the Jireugi velocity.

• 전기학회논문지
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• 제62권6호
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• pp.840-844
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• 2013

In this study, we try to estimate vascular compliance for management vascular disease. Because It is known the vascular compliance represents the state of the blood vessels. In general, the vascular compliance is estimated using an acceleration photoplethymogram from measured by photoplethymogram-based. The acceleration photoplethymogram is come from second derivative of photoplethymogram. By using the acceleration photoplethymogram, we can estimating vascular compliance, vascular age, vascular state. In this study, for measuring acceleration photoplethymogram we have developed a measurement device having analog filters. It has the advantage of miniaturization, low-power because it is simpler than digital filters. Using the developed device, we have estimated vascular compliance and tested the reliability of our device compare with conventional device having digital filters. As a result.

• 생명과학회지
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• 제33권9호
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• pp.730-735
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• 2023

지난 10년 동안 인공지능의 도움으로 노화를 정량화하기 위한 수많은 연구가 수행되었다. DNA 메틸화 데이터를 사용하여 다양한 모델이 개발되었으며 흔히 후성유전학적 시계라고 불린다. 후성유전학적 나이 가속화는 일반적으로 질병 상태와도 주로 연관이 있어 보인다. 조현병은 가속 노화 가설과 관련있는 정신질병으로 심각한 정신적, 신체적 스트레스를 동반한다. 다른 심리 질환과 비교했을 때 이 질병은 젊은 사람들에서 높은 사망률과 질병률을 유발한다. 과거 연구에서는 이 질병이 가속 노화 가설과 연관있다고 알려져 있었다. 이번 연구에서는 조현병 환자의 후성유전학적 나이 가속도 변화를 통해 질병에 대한 후성유전학적 통찰을 얻고자 하였다. 후성유전학적 나이 가속화를 측정하기 위해 두 가지 다른 DNA 메틸화 시계 모델을 사용했으며 이는 범조직 모델인 Horvath clock과 Epi clock을 사용하였다. 우리는 Horvath clock과 Epi clock이 모두 호환되는 450k 어레이 데이터를 사용하였다. 그 결과, Epi clock을 사용했을 때 환자샘플에서 후성유전학적 나이 가속화가 더 느리다는 것을 발견했다. Epi clock이 질병으로 인한 DNA 메틸화 변화를 잘 감지해낼 수 있음을 알아내었다. 또한 Epi clock에서 대조군과 환자군에서 차등적으로 메틸화된 CpG 부위를 분석하고 경로 농축 분석을 수행한 결과, 대부분의 CpG가 신경 세포 과정에 관여한다는 사실을 발견했다.

• International Journal of Internet, Broadcasting and Communication
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• 제15권1호
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• pp.177-183
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• 2023

The purpose of this study was to examine the effects of 8 weeks of resistance exercise on gait-related abilities and the differences in age groups to provide reference materials for application of training by age group. Subjects in their 30s, 40s, and 50s were recruited and subjected to a lower extremity exercise, in which the intensity gradually increased three times a week for eight weeks. The gait-related variables, torque at 0.18 sec, acceleration time, and torque at 30°, were assessed through isokinetic tests before and after the 8-week training. The torque at 0.18 sec showed a significant increase in the 50s group. There was no significant difference in acceleration time according to time and group. The torque at 30° showed a significant increase in the 30s group. In conclusion, 8 weeks resistance training can increase neuromuscular activity in adults in their 50s group, and changes in training variables are needed to increase torque at 30° that affects knee stabilization in adults over 40s group.

• 한국운동역학회지
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• 제30권2호
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• pp.145-154
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• 2020

Objective: The purpose of this study was to determine the relationship between impact and shear peak force, and tibia-accelerometer variables during running. Method: Twenty-five male heel strike runners (mean age: 23.5±3.6 yrs, mean height: 176.3±3.3 m/s, mean mass: 71.8±9.7 kg) were recruited in this study. The peak impact and anteroposterior shear forces during treadmill running (Bertec, USA) were collected, and impact shock variables were computed by using a triaxial accelerometer (Noraxon, USA). One-way ANOVA was used to test the influence of the running speed on the parameters. Pearson's partial correlation was used to investigate the relationship between the peak impact and shear force, and accelerometer variables. Results: The running speed affected the peak impact and posterior shear force, time, slope, and peak vertical and resultant tibial acceleration, slope at heel contact. Significant correlations were noticed between the peak impact force and peak vertical and resultant tibia acceleration, and between peak impact average slope and peak vertical and resultant tibia acceleration average slope, and between posterior peak (FyP) and peak vertical tibia acceleration, and between posterior peak instantaneous slop and peak vertical tibial acceleration during running at 3 m/s. However, it was observed that correlations between peak impact average slope and peak vertical tibia acceleration average slope, between posterior peak time and peak vertical and resultant tibia acceleration time, between posterior peak instantaneous slope and peak vertical tibial acceleration instantaneous slope during running at 4 m/s. Conclusion: Careful analysis is required when investigating the linear relationship between the impact and shear force, and tibia accelerometer components during relatively fast running speed.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2005년도 추계학술대회 논문집
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• pp.332-337
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• 2005

In order to investigate performance changes, the acceleration, vibration, and braking performance tests were carried out on the electric multiple units (EMUs) with over 20 years operation. According to the testing results, in vibration and braking performance, the similar performance results were obtained as compared with newly manufactured EMUs. However, in terms of acceleration performance, below reference value (3.0 km/h/s) has been obtained. This is mainly due to performance deterioration including traction motor. The precision diagnosis evaluation of deteriorated EMUs will be provided through the overall evaluation of corrosion testing and structural performance of car body.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2003년도 봄 학술발표회 논문집
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• pp.741-744
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• 2003

In this study, the influence of chemical admixture on early strength development of concrete is discussed. According to the results, fluidity with variation of kinds of chemical admixture is lower in the case of acceleration type than in the case of normal type. Setting time of naphthalene acceleration type is shortened by I hour, and that of melamine is nearly same, but that of polycarbonic acid is somewhat retarded in comparison with that of naphthalene normal type. Early compressive strength gains 5MPa in about 18hours regardless of the kinds of chemical admixture. But as time elapses, compressive strength is higher in order of polycarbonic acid, naphthalene and melamine type. The relativity between compressive strength and the rebound value of P-type schmidt hammer is also favorable at early age, and compressive strength of 5MPa is estimated at the rebound value of 22.

• 한국운동역학회지
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• 제31권1호
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• pp.16-23
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• 2021

Objective: The purpose of the study was to compare the acceleration and shock attenuation (SA) of the runners with/without low back pain (LBG vs. NLBG) while running at 2.5 m/s, 3.0 m/s, 3.5 m/s and 4.0 m/s. Method: 15 adults without low back pain (age: 23.13±3.46 years, body weight: 70.13±8.94 kg, height: 176.79±3.68 cm, NLBG) and 7 adults with low back pain (age: 27.14±5.81 years, body weight: 73.10±10.74 kg, height: 176.41±3.13 cm, LBG) participated in this study. LBG was recruited through the VAS pain rating scale. All participants ran on an instrumented treadmill (Bertec, USA). Results: The LBG shows statistically greater vertical acceleration at the distal tibia during running at 3.5 m/s and 4.0 m/s and greater shock attenuation from the distal tibia to the head during running at 3.5 m/s compared with the NLBG during running (p<.05). As the speed increased, there was a statistically significant increase in vertical/resultant acceleration and shock attenuation for both groups. Conclusion: The findings indicated that the runners with low back pain (LBG) experience greater impact and shock attenuation compared with non-low back pain group (NLBG) during fast running. However, it is still inconclusive whether high impact on the lower extremity during running is the main cause of low back pain in the population. Thus, it is suggested that the study on low back pain should observe the characteristics of impact during running with individuals' low back pain experience and clinical symptoms.

• 통합자연과학논문집
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• 제16권2호
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• pp.61-67
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• 2023

Human body ages differently due to environmental, genetic and pathological factors. DNA methylation patterns also differs depending on various factors such as aging and several other diseases. The aging clock model, which uses these differences to predict age, analyzes DNA methylation patterns, recognizes age-specific patterns, predicts age, and grasps the speed and degree of aging. Aging occurs in everyone and causes various problems such as deterioration of physical ability and complications. Alzheimer's disease is a disease associated with aging and the most common brain degenerative disease. This disease causes various cognitive functions disabilities such as dementia and impaired judgment to motor functions, making daily life impossible. It has been reported that the incidence and progression of this disease increase with aging, and that increased phosphorylation of Aβ and tau proteins, which are overexpressed in this disease and accelerates epigenetic aging. It has also been reported that DNA methylation is significantly increased in the hippocampus and entorhinal cortex of Alzheimer's disease patients. Therefore, we calculated the biological age using the Epi clock, a pan-tissue aging clock model, and confirmed that the epigenetic age of patients suffering from Alzheimer's disease is lower than their actual age. Also, it was confirmed to slow down aging.