• Asian-Australasian Journal of Animal Sciences
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• 제29권9호
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• pp.1222-1228
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• 2016

The objective of this research was to estimate genetic parameters and trends for length of productive life (LPL), lifetime number of piglets born alive (LBA), lifetime number of piglets weaned (LPW), lifetime litter birth weight (LBW), and lifetime litter weaning weight (LWW) in a commercial swine farm in Northern Thailand. Data were gathered during a 24-year period from July 1989 to August 2013. A total of 3,109 phenotypic records from 2,271 Landrace (L) and 838 Yorkshire sows (Y) were analyzed. Variance and covariance components, heritabilities and correlations were estimated using an Average Information Restricted Maximum Likelihood (AIREML) procedure. The 5-trait animal model contained the fixed effects of first farrowing year-season, breed group, and age at first farrowing. Random effects were sow and residual. Estimates of heritabilities were medium for all five traits ($0.17{\pm}0.04$ for LPL and LBA to $0.20{\pm}0.04$ for LPW). Genetic correlations among these traits were high, positive, and favorable (p<0.05), ranging from $0.93{\pm}0.02$ (LPL-LWW) to $0.99{\pm}0.02$ (LPL-LPW). Sow genetic trends were non-significant for LPL and all lifetime production traits. Sire genetic trends were negative and significant for LPL ($-2.54{\pm}0.65d/yr$; p = 0.0007), LBA ($-0.12{\pm}0.04piglets/yr$; p = 0.0073), LPW ($-0.14{\pm}0.04piglets/yr$; p = 0.0037), LBW ($-0.13{\pm}0.06kg/yr$; p = 0.0487), and LWW ($-0.69{\pm}0.31kg/yr$; p = 0.0365). Dam genetic trends were positive, small and significant for all traits ($1.04{\pm}0.42d/yr$ for LPL, p = 0.0217; $0.16{\pm}0.03piglets/yr$ for LBA, p<0.0001; $0.12{\pm}0.03piglets/yr$ for LPW, p = 0.0002; $0.29{\pm}0.04kg/yr$ for LBW, p<0.0001 and $1.23{\pm}0.19kg/yr$ for LWW, p<0.0001). Thus, the selection program in this commercial herd managed to improve both LPL and lifetime productive traits in sires and dams. It was ineffective to improve LPL and lifetime productive traits in sows.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.1861-1864
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• 2016

Although early diagnosis of thyroid nodule type is very important, the diagnostic accuracy of standard tests is a challenging issue. We here aimed to find an optimal combination of factors to improve diagnostic accuracy for distinguishing malignant from benign thyroid nodules before surgery. In a prospective study from 2008 to 2012, 345 patients referred for thyroidectomy were enrolled. The sample size was split into a training set and testing set as a ratio of 7:3. The former was used for estimation and variable selection and obtaining a linear combination of factors. We utilized smoothly clipped absolute deviation (SCAD) logistic regression to achieve the sparse optimal combination of factors. To evaluate the performance of the estimated model in the testing set, a receiver operating characteristic (ROC) curve was utilized. The mean age of the examined patients (66 male and 279 female) was $40.9{\pm}13.4years$ (range 15- 90 years). Some 54.8% of the patients (24.3% male and 75.7% female) had benign and 45.2% (14% male and 86% female) malignant thyroid nodules. In addition to maximum diameters of nodules and lobes, their volumes were considered as related factors for malignancy prediction (a total of 16 factors). However, the SCAD method estimated the coefficients of 8 factors to be zero and eliminated them from the model. Hence a sparse model which combined the effects of 8 factors to distinguish malignant from benign thyroid nodules was generated. An optimal cut off point of the ROC curve for our estimated model was obtained (p=0.44) and the area under the curve (AUC) was equal to 77% (95% CI: 68%-85%). Sensitivity, specificity, positive predictive value and negative predictive values for this model were 70%, 72%, 71% and 76%, respectively. An increase of 10 percent and a greater accuracy rate in early diagnosis of thyroid nodule type by statistical methods (SCAD and ANN methods) compared with the results of FNA testing revealed that the statistical modeling methods are helpful in disease diagnosis. In addition, the factor ranking offered by these methods is valuable in the clinical context.

• 노동경제논집
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• 제30권1호
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• pp.1-30
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• 2007

이 논문은 한국노동패널 조사자료를 이용하여 한국에서의 남성과 여성의 교육투자수익률을 추정하였다. Mincer 타입의 임금함수를 이용하여 평균적인 교육투자수익률을 추정해 본 결과, 남성과 여성의 교육투자수익률이 크게 차이가 나지 않은 것으로 나타났다. 이는 연령대가 높아질수록 남성의 수익률은 높아지고, 여성의 수익률은 낮아지는 현상 때문에 나타난 결과로 판단된다. 학위효과(sheepskin effect)를 추정해 보면, 대학 학위가 남성근로자의 임금에는 거의 영향을 주지 않으나, 여성에게는 큰 임금상승효과를 가져온다는 것을 발견하였다. 이는 대학교육이 남성보다 여성의 임금수준에 더 큰 영향을 미친다는 또 하나의 증거가 될 수 있다. 대학입학시험 성적 변수를 사용하여, 가능한 한 개인의 생산성 차이가 임금수준에 미치는 영향을 배제하고, 교육이 임금수준에 미치는 영향을 추정해 보고자 하였다. 그 결과 남성의 경우에는 교육이 임금수준에 미치는 영향이 거의 발견되지 않은 반면에, 여성의 경우 그 영향이 크고 유의하게 나타났다. 이러한 모든 발견들은, 교육수준이 여성의 임금수준에 보다 큰 영향을 미친다는 주장을 강하게 지지한다 하겠다. 따라서 기존의 연구에서 남녀를 구분하지 않거나 이 논문에서 남녀 간 평균 교육수익률이 큰 차이를 보이지 않은 것은 이 논문에서 제시하는 각종 원인에 의해 일부 왜곡된 것이며, 실제로는 여자가 더 높다는 것을 보인다. 또한 이는 미국을 비롯한 대부분의 OECD 국가의 경우와도 일치한다.

• 한국산림과학회지
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• 제97권4호
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• pp.437-444
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• 2008

본 연구는 자연휴양림 내에서 휴양지구를 설정하기 위한 방법을 모색하기 위하여 산림휴양기능의 평가를 시도하였다. 청옥산 자연휴양림을 연구대상지로 선정하고, 표준지 173개 소반을 추출하여 수량화II류를 이용하여 분석하였다. 이때 외적기준은 산림휴양 효용의 정도를 전문가로부터 부여받았고, 설명변수는 기존의 연구결과와 대상지의 산림휴양자원을 고려하여 임상, 임령, 경사, 수변, 도로, 시설의 6인자를 선정하였다. 그 결과, 절대판별적중률은 제 1 2상관비 축에서 각각 82%, 75%로서 예측 가능한 판별 정도(精度)를 얻었다. 요인으로서는 도로와 경사가 산림휴양기능의 잠재력에 큰 영향을 미치고 있으며, 카테고리에 있어서는 도로가 있는 것이, 경사는 낮을수록 산림휴양기능을 높이는 방향으로 작용하는 것을 알 수 있었다. 또한, 청옥산 자연휴양림의 소반별 산림휴양기능의 잠재력을 평가하기 위하여 표준지에서의 예측식을 사용하여 산림휴양효용의 정도를 나타내는 종합점수를 구한 다음, 판별구분점에 의하여 높다(H), 보통(M), 낮다(L)로 3구분하였으며, GIS를 이용하여 분포를 나타내는 평가도를 작성하였다. 수량화라는 형식을 매개로 하여 산림휴양의 효용의 정도에 관한 현실의 직관적 경험적 종합판단을 평가인자와 카테고리가 개입된 분석적 판단으로 변환하고 있는 점에 본 연구의 의의가 있다.

• Asian-Australasian Journal of Animal Sciences
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• 제31권4호
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• pp.473-479
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• 2018

Objective: The study was designed to perform a genome-wide association (GWA) and partitioning of genome using Illumina's PorcineSNP60 Beadchip in order to identify variants and determine the explained heritability for the total number of teats in Yorkshire pig. Methods: After screening with the following criteria: minor allele frequency, $MAF{\leq}0.01$; Hardy-Weinberg equilibrium, $HWE{\leq}0.000001$, a pair-wise genomic relationship matrix was produced using 42,953 single nucleotide polymorphisms (SNPs). A genome-wide mixed linear model-based association analysis (MLMA) was conducted. And for estimating the explained heritability with genome- or chromosome-wide SNPs the genetic relatedness estimation through maximum likelihood approach was used in our study. Results: The MLMA analysis and false discovery rate p-values identified three significant SNPs on two different chromosomes (rs81476910 and rs81405825 on SSC8; rs81332615 on SSC13) for total number of teats. Besides, we estimated that 30% of variance could be explained by all of the common SNPs on the autosomal chromosomes for the trait. The maximum amount of heritability obtained by partitioning the genome were $0.22{\pm}0.05$, $0.16{\pm}0.05$, $0.10{\pm}0.03$ and $0.08{\pm}0.03$ on SSC7, SSC13, SSC1, and SSC8, respectively. Of them, SSC7 explained the amount of estimated heritability along with a SNP (rs80805264) identified by genome-wide association studies at the empirical p value significance level of 2.35E-05 in our study. Interestingly, rs80805264 was found in a nearby quantitative trait loci (QTL) on SSC7 for the teat number trait as identified in a recent study. Moreover, all other significant SNPs were found within and/or close to some QTLs related to ovary weight, total number of born alive and age at puberty in pigs. Conclusion: The SNPs we identified unquestionably represent some of the important QTL regions as well as genes of interest in the genome for various physiological functions responsible for reproduction in pigs.

• Asian-Australasian Journal of Animal Sciences
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• 제30권11호
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• pp.1550-1556
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• 2017

Objective: This study estimated the genetic parameters for productive and reproductive traits. Methods: The data included production and reproduction records of animals that have calved between 1979 and 2013. The genetic parameters were estimated using multivariate mixed models (DMU) package, fitting univariate and multivariate mixed models with average information restricted maximum likelihood algorithm. Results: The estimates of heritability for milk production traits from the first three lactation records were $0.03{\pm}0.03$ for lactation length (LL), $0.17{\pm}0.04$ for lactation milk yield (LMY), and $0.15{\pm}0.04$ for 305 days milk yield (305-d MY). For reproductive traits the heritability estimates were, $0.09{\pm}0.03$ for days open (DO), $0.11{\pm}0.04$ for calving interval (CI), and $0.47{\pm}0.06$ for age at first calving (AFC). The repeatability estimates for production traits were $0.12{\pm}0.02$, for LL, $0.39{\pm}0.02$ for LMY, and $0.25{\pm}0.02$ for 305-d MY. For reproductive traits the estimates of repeatability were $0.19{\pm}0.02$ for DO, and to $0.23{\pm}0.02$ for CI. The phenotypic correlations between production and reproduction traits ranged from $0.08{\pm}0.04$ for LL and AFC to $0.42{\pm}0.02$ for LL and DO. The genetic correlation among production traits were generally high (>0.7) and between reproductive traits the estimates ranged from $0.06{\pm}0.13$ for AFC and DO to $0.99{\pm}0.01$ between CI and DO. Genetic correlations of productive traits with reproductive traits were ranged from -0.02 to 0.99. Conclusion: The high heritability estimates observed for AFC indicated that reasonable genetic improvement for this trait might be possible through selection. The $h^2$ and r estimates for reproductive traits were slightly different from single versus multi-trait analyses of reproductive traits with production traits. As single-trait method is biased due to selection on milk yield, a multi-trait evaluation of fertility with milk yield is recommended.

• Asian-Australasian Journal of Animal Sciences
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• 제30권12호
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• pp.1674-1678
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• 2017

Objective: The aim of the study was to evaluate genetic correlations between the behavioural profile and performance in laying hens as an indirect answer to the question whether the observed behavioural responses are associated with increased levels of stress in these birds. Methods: The assessment of birds' temperament was carried out using the novel objects test. The behavioural test was conducted in two successive generations comprising 9,483 Rhode Island White (RIW) birds (approx. 4,700 individuals per generation) and 4,326 Rhode Island Red (RIR) birds (approx. 2,100 individuals per generation). Based on the recorded responses, the birds were divided into two groups: a fearful profile (1,418 RIW hens and 580 RIR hens) and a brave/curious profile (8,065 RIW hens and 3,746 RIR hens). The birds were subjected to standard assessment of their performance traits, including SM, age at sexual maturity; ST, shell thickness; SG, egg specific gravity; EW, mean egg weight; IP, initial egg production; and HC, number of hatched chicks. The pedigree was three generations deep (including two behaviourrecorded generations). Estimation of the (co)variance components was performed with the Gibbs sampling method, which accounts for the discrete character of the behavioural profile denotation. Results: The analyses revealed negative correlations between the performance traits of the laying hens and the behavioural profile defined as fearful. In the group of fearful RIW birds, delayed sexual maturation (0.22) as well as a decrease in the initial egg production (-0.30), egg weight (-0.54), egg specific gravity (-0.331), shell thickness (-0.11), and the number of hatched chicks (-0.24) could be expected. These correlations were less pronounced in the RIR breed, in which the fearful birds exhibited a decline in hatchability (-0.37), egg specific gravity (-0.11), and the number of hatched chicks (-0.18). There were no correlations in the case of the other traits or they were positive but exhibited a substantial standard error, as for the egg weight. Conclusion: To sum up the results obtained, it can be noted that behavioural responses indicating fearfulness, i.e. escape, avoidance, and approach-avoidance may reflect negative emotions experienced by birds. The negative correlations with performance in the group of fearful hens may indirectly indicate a high level of stress in these birds, especially in the white-feathered birds, where stronger performance-fearfulness correlations were found. Fearful birds should be eliminated from breeding by inclusion of the behavioural profile in the selection criterion in the case of laying hens.

• 대한간호학회지
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• 제16권3호
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• pp.108-122
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• 1986

Changing concepts of health care, are stimulating the demand for health care, thereby orienting society to health care rights to such an extent that they are deemed as fundamental ones inalienable to man. Concomitantly, qualitative as well as quantative improvement is being sought in the nursing service field. Today, efforts are being made in various areas, especially to qualitatively improve nursing services. A second issue concerns proper staffing. It is important to study staffing, in as much as it continues to be the most persistent and critical problem facing hospital nursing administrators today. It involves quantity, quality, and utilization of nursing personnel. A great deal of attention has been focused on this problem since mid 1930's when nursing services began to be felt as an important segment of hospital operation representing the largest single item of hospital budgets. Traditionally, the determination and allocation of nursing personnel resources has relied heavily on gloval approaches which make use of fixed staff-to-patient ratios. It has long been recognized that these ratios are insensitive to variations between institutions and among individual patients. Therefore, the aim of this thesis is to point to the urgent need for the development of methodology and criteria suited to the reality of Korea. The present research selected one place, the W Christian Hospital, and was conducted over a period 10 days from January, and nurses who were them on duty in their unit. The total num-her of patients surveyed was 1,426 and that of 354. The research represents many variables affecting the direct patient care time using the result from the direct observation method, then using a calculation method to estimate the relationship between the patients care time and selected variables in the hospital setting. The amount of direct patient care time varies with many factors, such 89 the patients age. diagnosis and time in hospital. Differences are also found from hospital, clinic to clinic, ward to ward, and even shift to shift. In this research, the calculation method of estimating the required member of nursing staff is obtained by dividing the time of productive patient care activity(with the time of patient care observed), by the sum of the productive time that each the staff can supply, i.e., 360 minutes, which is obtained by deducting the time for personal activities. The results indicate a substantial difference between the time of productive patient care observed directing and the time of the productive patient care estimated using calculating method. If we know accurately the time of the direct patient care on a shift, there required number of staff members calculated if the proper method can be determinded should be able the time of the direct patient care be estimated by the patient classification system, but this research has shown this system to be in accurate in Korea. There are differences in the recommended time of productive patient care and the required number of nursing staff depending upon which method is used. The calculated result is not very accurate, so more research is needed on the patient classification system.

• Nutrition Research and Practice
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• 제6권5호
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• pp.436-443
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• 2012

Previous Korean total diet studies (KTDSs) have estimated dietary exposure to toxic chemicals based on 110-120 representative foods selected from over 500 foods appeared in the Korea National Health & Nutrition Examination Surveys (KNHANES), which would result in a possible underestimation. In order to find measures for a closer-to-real estimate of dietary exposure to heavy metals, this study examined the feasibility of mapping foods to the representative foods in the KTDS by comparing estimates. In mapping, those foods not analyzed in the 2009 KTDS (443 out of 559 foods appeared in the 2007 KNHANES) were mapped to the 114 representative foods used in the 2009 KTDS based on the closeness in regards to biological systematics and morphological similarity. Dietary exposures to total mercury and lead were re-estimated using the content of total mercury and lead in 114 foods analyzed in the 2009 KTDS, food intake, and individual's own body weight for respondents in the 2007 KNHANES instead of mean body weight of Koreans used in the 2009 KTDS. The re-estimates of exposure with mapping were approximately 50% higher than the original estimates reported in the 2009 KTDS. In addition, mapping enabled the comparison of percentile distribution of the exposure among populations of different age groups. In conclusion, estimates via mapping resulted in a more comprehensive estimation of dietary exposure to heavy metals present in foods that Koreans consume.

• Journal of Animal Science and Technology
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• 제44권6호
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• pp.685-692
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• 2002

본 연구는 농협중앙회 가축개량사업소와 한우개량단지에서 1991년도부터 1996년도까지 출생하여 사육된 1,823두의 한우 수소에 대한 자료를 이용하여 성장형질과 도체형질의 유전상관을 추정하기 위하여 실시하였으며, DF- REML을 이용한 다형질 Animal Model로 추정하였다. 12개월 체중과 일당증체량은 0.76, 12개월 체중과 체장은 0.79의 유전상관을 나타내었고, 18개월 체중과 일당증체량 및 18개월체중과 체장간의 유전상관은 각각 0.86 및 0.82로 추정되었다. 또한 냉도체중과 도체율, 배최장근단면적, 등지방두께 및 도체장간의 유전상관은 각각 0.39, 0.37, 0.44, 0.63으로 추정되었고, 등지방두께와 근내지방도는 0.36의 유전상관을 나타내었다. 냉도체중과 12개월 체중 및 18개월체중간의 유전상관은 0.71과 0.96으로 높은 정의 상관을 나타내었고, 체장과의 유전상관도 0.63과 0.75로 체중과 유사한 경향을 나타내었다. 도체율과 체중, 일당증체량, 체장, 곤폭 및 흉위간에는 정의 유전상관을 나타냈으며, 배최장근단면적과 성장형질간의 유전상관은 -0.07 ${\sim}$0.32으로 낮게 추정되었고, 등지방두께와 성장형질간 유전상관은 낮게 추정되었지만 18개월령 흉위에서 높게 나타났다. 근내지방도와 18개월 흉위는 0.25의 유전상관 상관이 추정되었다.