• Asian-Australasian Journal of Animal Sciences
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• 제23권10호
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• pp.1276-1281
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• 2010

The present study was conducted to investigate the effects of butylated hydroxytoluene (BHT) supplementation on diluted, cooled and frozen-thawed ram spermatozoa. After primary evaluation of collected ejaculates, only semen samples with motility of more than 70% and sperm concentration higher than $3{\times}10^3$ sperm/ml were used for cryopreservation. The selected semen samples were then pooled and diluted 1:4 with Tris Citrate Fructose Yolk (TCFY) extender supplemented with different concentrations of BHT (0.5, 10, 2.0 and 3.0 mM). As the control, semen was diluted and frozen in the diluent without BHT. Motility, progressive motility, viability, membranes and acrosome integrity were evaluated after dilution (part 1), cooling (part 2) and freezing and thawing (part 3). The results of the first part of the experiment showed that there were no significant difference between treatments in the motility, progressive motility, viability, membranes and acrosome integrity of spermatozoa, but the results with 2.0 mM BHT were slightly better than obtained with other levels of BHT and control extender. Significantly better results (p<0.05) were observed in the second part of the experiment for cooled spermatozoa characteristics, when extender was supplemented with 2.0 and 3.0 mM BHT. Furthermore, the results obtained in the third part of the experiment indicated that, after freezing and thawing, all evaluated semen characteristics were improved significantly (p<0.05) by increasing BHT levels, with the best results obtained for extender containing 2 mM BHT. Comparison of these results with those of control diluent, the effects of supplementation were significantly (p<0.01) better. However, the higher concentration of BHT (3.0 mM) reduced the motility, acrosomal integrity, viability and hypo-osmotic swelling response of spermatozoa compared to extender containing 2.0 mM BHT. In conclusion, the results obtained in this study showed that the semen quality of rams was improved when BHT was added to extender used before the freezing process.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 1996년도 특별강연 및 춘계학술발표 개요집
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• pp.34-37
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• 1996

The expanding method of tube to tubesheet joint part on neclear steam generators are classified into three classes of roller expanding, explosive expanding and hydraulic expanding. After the expanded Mock-Up specimen are made by the three expanding method. The general properties, microstructure/microvickers hardness, pull-out strength, hydraulic leak pressure, of tube to tubesheet joint part were inspected. and We evaluated the operation efficiency of expansion, reproduction of expanded joint about three expanding method. Through the overall evaluation of tube to tubesheet joint part, The hydraukic expanding and explosive expanding could be certificated more useful expanding method.

• 대한물리치료과학회지
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• 제13권2호
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• pp.47-55
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• 2006

This study was executed in order utilized five typical taping therapy spending on upper limb end part, and to grasp an influence on shoulder pain of upper limb part among spiral balance taping therapy of Danaca. This study was performed at Physical therapy Dept. of Gyeongbuk H orthopedics until 2005 November 4 from 2005 October 4th. This study appealed for a shoulder pain, and visited all 25(15 Non capsular lesions, 10 capsular lesions) patients to the objects. We executed study to the objects to a patient to agree with us after explaining a purpose and object of this study. Urged warning, and all executed eight times over about the patient who executed taping therapy for five weeks so as not to be able to get other therapy treatment. Application way of taping therapy applied all once at random generally five taping therapy to apply to limbs end of upper at clinical so far. Operated on the results about pain decrease, and we calculated as compared before and after five taping therapy. Also, operated again on them in a taping therapy judged that there was pain decrease, and we returned them to home. We make a comparative analysis for a pain after and before a treatment as we use the VAS which is evaluation of a pain in this study. The results of this study are as follows. Appeared so as operated, and a pain decrease change of Non capsular lesions became lower with a the average of 2.3 after a taping therapy in the average of 6.4s former a treatment, and to note statistically later Taping therapy of upper limb end part.(P<0.01). The pain decrease change of capsular lesions of a shoulder joint pain index decreased with the average of 4.0 after a taping therapy treatment in the average of 6.0 former a treatment after Taping therapy of upper limb end part, but were not able to note statistically.(P>0.05) Taping therapy of upper limb end part is positive to pain decrease of shoulder joint in the above-mentioned study can affect, and can especially get the effective conclusion that was able to affect from pain decrease of Non capsular lesions.

• 한국약용작물학회지
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• 제11권3호
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• pp.186-189
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• 2003

고추냉이 시기별 생육특성을 검정하기 위하여 정식 후 10개월과 15개월에서 수확하여 특성을 조사한 결과 10개월에 비하여 15개월에서 지상부 생육 중 엽장, 엽폭, 주경엽수 등은 큰 증가를 보였으나, 총엽수, 얼자수 등은 감소하였다. 근경의 건물 분배율은 정식 10개월에서는 엽병 > 엽> 근경 > 분지경 순서이었으나, 15개월에서는 엽병 > 근경 > 엽 > 분지경 순서였다. 근경의 경도 및 allylisothiocyanate함량은 10개월에 비하여 15개월에서 13배 정도 높았다. 근경의 건물율은 10개월에서는 두부와 미부간에 큰 차이가 있었으나 15개월에서는 차이가 없었다.

• The Journal of Korean Physical Therapy
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• 제15권3호
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• pp.1-15
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• 2003

The purpose of this study was to evaluate the change of lower extremity alignment according to plantar surface compliance in standing status. The thirty normal adults (15 men and 15 women) aged between 20 and 29 were assigned to 3 groups: control group, experimental groups (AHPS group, ASPH group). The lower extremity alignment was examined before and after adaptation with corresponding foam types. The results of this study were as follows : 1. As the result of comparing lower extremity alignment before and after test of the control group which any change did not exist in plantar surface compliance, there were not significant differences in the angle A, B, C, D, E of right and left(p>0.05). 2. As the result of comparing lower extremity alignment before and after test of the AHPS group which forefoot part of plantar surface is hard and rear foot part is soft, there were not significant differences in the angle A of right and left(p>0.05). But, there were significantly decreased in the angle B, C, D, E of right and left(p<0.05). 3. As the result of comparing lower extremity alignment before and after test of the ASPH group which forefoot part of plantar surface is soft and rear foot part is hard, there were not significant differences in the angle A of right and left(p>0.05). But, there were significantly increased in the angle B, C, D, E of right and left(p<0.05). 4. As the result of comparing lower extremity alignment of the control group, AHPS group and ASPH group, there were not significant differences in the angle A, B, C, D, E of right and left before test(p>0.05). But, there were significant differences in the angle C, D of right and left after test(p<0.05).

• Journal of Veterinary Science
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• 제22권5호
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• pp.47.1-47.10
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• 2021

Background: Due to multiple similarities in the structure and physiology of human and pig skin, the pig model is extremely useful for biological drug testing after subcutaneous administration. Knowledge of the differences between subcutaneous injection sites could have a significant impact on the absorption phase and pharmacokinetic profiles of biological drugs. Objectives: This study aimed to analyze the impact of administration site on pharmacokinetics and selected biochemical and hematological parameters after a single subcutaneous administration of ustekinumab in pigs. Drug concentrations in blood plasma were analyzed by enzyme-linked immunosorbent assay. Pharmacokinetic analyses were performed based on raw data using Phoenix WinNonlin 8.1 software and ThothPro v 4.1. Methods: The study included 12 healthy, female, large white piglets. Each group received a single dose of ustekinumab given as a 1 mg/kg subcutaneous injection into the internal part of the inguinal fold or the external part of the inguinal fold. Results: The differences in absorption rate between the internal and external parts of the inguinal fold were not significant. However, the time of maximal concentration, clearance, area under the curve calculated between zero and mean residence time and mean residence time between groups were substantially different (p > 0.05). The relative bioavailability after administration of ustekinumab into the external part of the inguinal fold was 40.36% lower than after administration of ustekinumab into the internal part of the inguinal fold. Conclusions: Healthy breeding pigs are a relevant model to study the pharmacokinetic profile of subcutaneously administered ustekinumab.

• 농촌계획
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• 제25권3호
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• pp.129-139
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• 2019

The purpose of this study is to monitor the long-term vegetation change of the village complementary forest after restoration. Based on the monitoring in 2010, six years after the restoration project in 2004, the monitoring of the complementary forest in Dubang village in 2019 after 9 years was conducted. This study identifies the change of species diversity and structure, growth, vegetation coverage, structural quality etc. and succession through long-term monitoring. For this, field survey was conducted in 2003 and 2010, 2019. The results demonstrate significant increase of species diversity and multi-layer structure and progress of natural succession. Overall, Part I is considered to be a quasi-natural complementary village forest, which has a natural balance between natural vegetation that have remained in nature for a long time and anthropogenic vegetation, revealing the coexistence of nature and humanity. It means ecological structure and function have improved. Part II should be restored to the lost part and adaptive management rather than excessive management should be carried out to leave natural succession.

• Biotechnology and Bioprocess Engineering:BBE
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• 제10권5호
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• pp.400-407
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• 2005

Reverse engineering is defined as the process where the internal structures and dynamics of a given system are inferred and analyzed from external observations and relevant knowledge. The first part of this paper surveys existing techniques for biosystem reverse engineering. Network structure inference techniques such as Correlation Matrix Construction (CMC), Boolean network and Bayesian network-based methods are explained. After the numeric and logical simulation techniques are briefly described, several representative working software tools were introduced. The second part presents our component-based software architecture for biosystem reverse engineering. After three design principles are established, a loosely coupled federation architecture consisting of 11 autonomous components is proposed along with their respective functions.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2010년도 춘계학술발표대회
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• pp.4.1-4.1
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• 2010

In the first part, after discussing works on nacre, a soft-hard composite found in nature, including a simulation on network mimicking nacre [1-4], we talk on a simple model of spider webs, another example of natural soft-hard structure [5]. We demonstrate that the web network is free of stress concentrations because the radial threads are stronger than the spiral threads. In the second part, after reviewing our works on wetting on textured surfaces [6-8], we discuss penetration into textured surface and instability of a liquid film on textured substrates during spin coating [9,10].

• Journal of Preventive Medicine and Public Health
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• 제27권1호
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• pp.107-116
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• 1994

The United States adopted DRG based prospective payment system (PPS) in order to control the inflation of health care costs. No study used statistical test while many studies reported the cost containing effect of the PPS. To study impacts of the PPS on the Medicare expenditure, this study set the following three hypotheses (1) The PPS decelerated the increase in the hospital expenditure (Part A), (2) the PPS accelerated the increase in the expenditure of outpatients and physicians (Part B), (3) the increase in total expenditure was decelerated inspite of the spill over (substitution) effect because saving in the Part A expenditure were greater than losses in the Part B expenditure. The dependent variables are per capita hospital expenditure, per capita Part B expenditure, and per capita total expenditure for the Medicare beneficiaries. An intervention analysis, which added intervention effect to the time series variation on the Box-Jenkins model, was used. The observations included 120 months from 1978 to 1987. The results are as follows : (1) The annual increase in the per capita Part A expenditure was $5.11 after the implementation of DRG where as that before the PPS had been $11.1. The effect of the reduction ($5.99) was statistically significient (t=-3.9). (2) The spill over (substitution) effect existed because the annual increase in the per capita Part B expenditure was accelerated by $1.73 (t=1.91) after the implementation of the PPS. (3) The increase in the total Medicare expenditure per capita was reduced by $4.26 (t=-2.19) because the spill over effect was less than cost savings in the Part A expenditure.