The three important phases in the development of ligand immunoassays are identified and summarized. The competitive radiolabelled hormone measurement had been developed in the first and early in the second generations(1950s to 1960s), such as radioimmunoassays(RIA) or immunoradiometric(saturation) assays(IRMA), and used in all most of the hormone and also analyte in biological samples. In the second generation, ultrasensitive non-isotopic immunoassays(NIA) were developed using monoclonal antibodies(McAb), labelling the McAb and high specific activity non-isotopic labels. After their usefulness, advantages and disadvantages has been evaluated and non-competitive methods are discussed. The chip/microarray based multianalyte ligand assays(microspot or genechip methods) are developed and known as alternative ones in the third generation. We summarize the developments of NIAs and its usefulness, and then introduce briefly the new ligand assays.
Since 1950s' we have come to take a deep interest in matrimonial communication as the theories of family therapy though communication came to extend. In the rapid changing modem society, especially, the dysfunctional aspect of the communication rather than functional one tends to grow high because married couples who suffer from isolation and solitary in social life want to satisfy their unfilled desire through matrimonial communication and apt to be hurt easily by their attitudes and behaviors. When these discrepancies in dysfunctional aspect take place repeatedly, the conflict between married couple which is bad in their psychological effects go from bad to worse and influence their somatic symptoms. This study was attempted to examine the relationship between dysfunctional communication patterns of married couple and complaint degree of housewives psychosomatic symptoms and to use as basic materials focusing on nursing system centered around family, which aims to reach the family centered culture of Korea. To gain the aims, some surveys were peformed at Seoul, Chinju and some areas of Kyeongki province, and the study materials were collected from 70 wives who were encountered by 12 pastrolists majoring in clinical pastrol of ‘Y’ Theological Graduate School and from neurotic patients of those who visited the internal Medicine depts of 1 university hospital and 4 hospitals ‘J’ city, among whom they used dysfunctional communication pattern in their married life. And data collection was peformed from Feb. 22, 1988 to April 22. In the survey, four types of dysfunctional communication presented by Song Sung-Ja were used as the survey tool. And the complaint degree on Psychosomatic symptoms was measured by the classification according to the complaint degree of housewives's psychosomatic symptoms through pretest after content validity, in which the housewives who dysfunctional communication wert surveyed. To learn matrimonial Communication patterns that have an effect on housewives psychosomatic symptoms in the surveyed.
Films of the 1960s in both Korea and Egypt share many common characteristics. These include the main trend of such films' in addition to some of the political situations. This trend mainly relates to the adaptation of novels into films. In the late 1940s, Andre Bazin wrote his ideas about a similar phenomenon in Europe and the United States. Based on Bazin's thoughts and other examples for films adapted from novels in the 1940-60s, I found that the trend in both Korea and Egypt can be explained as an international phenomenon, in which film developed to a further stage due to a dialectic between content and form after the increase in the development of film techniques. The trend in Korea is believed to have led to the so-called golden era of Korean movies, while in Egypt films adapted from literature were not able to earn high profits, even though in a 1996 list of the best 100 Egyptian films, 23 had been adapted from novels. To explain the reasons behind this phenomenon, I looked into the internal demand from filmmakers themselves to further develop the industry through the articles written at that time. In addition, I explored the different situations and policies that influenced film production in both countries in the 1960s. I found that political situations and policies could have helped in the continuity of such trend, but it is difficult to consider these as the main reason for its creation, in contrast to the internal demand, which I believe is the main reason for the creation of such direction.
Macrodystrophia lipomatosa (MDL) is a rare congenital non-hereditary disorder that has significant impact on patient morbidity. This study provides a comprehensive review of the natural history, diagnosis, management, and outcomes of the disorder. A literature search in PubMed was conducted to identify cases of MDL from January 1950 to 14 February 2014. After ruling out articles without information related to the management of the disorder, a summary of 32 studies was performed. An additional three cases from the authors are also presented. Based on 57 journal articles and three additional cases from the authors, around 108 cases of MDL were reviewed. Most patients were males who were admitted to a treatment clinic in the first four years of life. The lower extremities were more frequently affected, with unilateral presentation being most common. They commonly underwent a single-staged surgical procedure with follow-up periods ranging from more than one year up to 21 years. Out of 43 cases that underwent surgical procedures, 13 reported no complications, and there were seven cases of esthetic satisfaction and 15 cases of significant functional improvement. Depending on the severity of a patient's condition, the use of non-invasive diagnostic tools should be carefully considered. Surgery might be a better choice of management than observation, taking into account possible future complications in the absence of surgery and the beneficial outcomes of surgical procedures.
The water-rock interaction and anthropogenic contamination affecting to geochemical composition of shallow and deep groundwaters were investigated in the agricultural area of Myunggok-ri, Kongju. The shallow groundwater is classified into the chemical types of $Ca-HCO_3$ and $Ca-Cl(SO_4)$ and shows weak acid having an average pH 6.2. Deep groundwater shows the uncontaminated composition of the chemical types of $Na-HCO_3$ and Na $(Ca)-HCO_3$ with pH of 8.4~8.8. The grouping approach of chemical data of waters shows the distinguished trend between water composition influenced anthrophogenic input and water composition mainly determined by natural process such as water-rock interaction. The main anthropogenic inputs affecting chemical composition of shallow groundwater are the contaminants such as $K^+$, $NO_3{^-}$, $Cl^-$ having average values of 4.4 mg/l, 22 mg/l, 13.7 mg/l, respectively. The contaminants were probably derived from fertilizer, sweage, septic tank, and stable, etc. The hydrogen and oxygen isotopic compositions indicate that five deep groundwaters were recharged from different altitudes, and that shallow and deep groundwaters were originated from meteoric water. Tritium contents of waters suggest that deep groundwater was recharged before or just after 1950s, and that shallow groundwater is much younger than deep groundwater. The results of this study may serve as a basic data for the future study of shallow groundwater as a drinking water in agricultural area, in Korea.
The purpose of this study is to study the movie costume and color image through the movie"Vertigo". Firstly, looking into the clothing style and the color image of the characters expressed in the movie, Scottie who had the physical limitation had phobia of height, and he was expressed with the gray color to show his lethargic feeling from his physical limitation. And, after the death of Madeleine, it expressed his sense of loss and depressed mind through the blue color. The comparison of green and red color that was used to link the two characters in Madeleine and her substitution, Judy, mystified her, and the image of dreamy Madeleine has been inscribed to Scottie. In addition, the green color expressed her unstable mind. The clothing expression of Judy is expressed with her unstable mind through the detailed clothing, unlike Madeleine. And, the black color expressed the false identity of her and the Madeleine image of his own for Scottie. The type of clothing is expressed in separates suit and overcoat that are representative ones in 1950s, and black dress with the square neckline and others expressed the silence on conspiracy of Gavin and the false identity of her. Secondly, the color image expressed in the background in the movie as a special space for Scottie and Madeleine. The blue color image for Scottie was shown to be as space for death and the green image for Madeleine as a fantasy.
Journal of the Korean association of regional geographers
/
v.10
no.2
/
pp.479-496
/
2004
This study attempts to examine Egyptian agricultural development with regard to the social and political changes in the Egypt, and tries to explore the patterns of major crops and those spatial distribution nowadays. Also, land reclamation processes and farming activities are explained. Agricultural development in Egypt has been considerably affected by historical international trade, and those crops such as cotton and sugar cane have been especially protected and controlled as strategic crops by the Egyptian governments. The issues of land ownership have been varied with political environments by periods, but the controls to the strategic crops have been consistently maintained to a degree though some variations. since the 1990s, national liberalization programs also caused to change the agricultural policies which have affected the adjustments of crop production and land use. Spatial distribution of major crops and farming activities are examined in relation to natural environments by Delta, Middle and Upper Egypt, desert areas. The projects of land reclamation after 1952 are evaluated with the effects of government intervention, and the actors in use of the reclaimed lands are investigated.
Journal of the Korean Institute of Electrical and Electronic Material Engineers
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v.23
no.3
/
pp.190-193
/
2010
Various power semiconductor devices have been developed and evolved since 1950s. Among them, IGBT is the most developed power semiconductor device which has high breakdown voltage, high current conduction and suitable switching speed which perform trade-offs between each other. In other words, there are trade-offs between a breakdown voltage and on-state voltage drop, and between on-state voltage drop and turn-off time. In this paper, the new structure is proposed to improve a trade-off between a breakdown voltage and on-state voltage drop. The proposed structure has a trench collector and this trench collector induces an accumulation layer at the bottom of an n-drift region during off-state. And this accumulation layer prevents expansion of depletion layer so that trapezoidal electric field distribution is performed in the n-drift region. As a result of this, breakdown voltage is increased without increasing on-state voltage drop. The electrical characteristics of the proposed IGBT is analyzed and optimized by using representative device simulator, TSUPREM4 and MEDICI. After optimization, the electrical characteristics of the proposed IGBT is compared with NPT IGBT which have the same device thickness. As a result of this, it can be confirmed that the proposed structure increases the breakdown voltage of 800 V than that of the conventional NPT IGBT without increasing the on-state voltage drop.
Proceeding of Spring/Autumn Annual Conference of KHA
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2002.11a
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pp.307-313
/
2002
Urban style row-rise houses for rent have been supplied to the center of city from the 1950's first half The amount of stock is about 450,000 houses and occupies about 40% in the private rented house. As for the structure, the 60% of them is wooden-structure and the rest is non-wooden. Stocks of 57.5% of the wooden-structure and 86% of the non-wooden were built after 1981 years. It was 1981 years that the new earthquake-resistant standard was carried out, the improvement of stocks built before 1981 is necessary because those don't satisfy the present standard. To investigate the renovation possibility of urban style row-rise houses for rent, actual situation of two-story apartment at 2,4, and 5 Chome Taito-Ku in Tokyo was surveyed from July to November 2001. The number of building analyzed is 227 ridges among 234 ridges of the surveyed two-story building. 90% of building analyzed is wooden structure. 1) The site of 88% building surveyed is close to a road less than 4m width. It becomes the existing non-conformed building in the building construction act. It is impossible to make a renovation such as rebuilding, extension and remodeling because it requires the set back when renovating this type of non-conformed building, 2) The building built before 1981 is almost wooden-structure, and occupies 37% of the building surveyed, and doesn't satisfy the present earthquake-resistant standard. An improvement of them is needed because the decrepitude of building proceeds. 3) 50% of openings and 40% of windows of the building surveyed doesn't use noncombustible materials. Though it becomes the existing non-conformed building, it can satisfy the present standard by replacing openings with noncombustible materials.
Flux Cored Arc Welding (FCAW), which has been widely used in many industries, was developed in the 1950s to supplement shortcomings of the Shielded Metal Arc Welding (SMAW). FCAW has an advantage in that it can weld regardless of postures and give good quality results in the filed with many different working conditions. In this study, SM490A (rolled steel for welding structural purpose) with different thicknesses (L:25T+R:30T) were welded using FCAW. Then the mechanical properties (tension test, bending test, hardness test, impact test and macro test) were analyzed and the following conclusions were drawn. In the tensile test, it exceeds the KS standard tensile strength range (400~510) in all welding positions, which means there is a problem in the tensile force transmission performance. In the bending test, it was found that most of the specimens did not exhibit surface rupture or other defects during bending test and they exhibit sufficient toughness even after plastic deformation. In the hardness test, all the results were lower than the standard value of 350 Hv of KS B 0893, which means they have good hardness. In the impact test, all results were larger than the KS reference value of 27J. In the macro test, they showed uniform structure state by the shape of the weld, and there was risk of lamination because no internal defects, bubbles, or impurities were found on the surface of the weld.
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