• 한국수자원학회:학술대회논문집
• /
• 한국수자원학회 2005년도 학술발표회 논문집
• /
• pp.1398-1402
• /
• 2005

Riverbank filtration is a natural process using alluvial aquifers to remove contaminants and pathogens in river water for the production of drinking water. In riverbank filtration, the understanding of contaminant transport is an important task for the production of high quality drinking water. This study investigates the transport behavior of hydrophobic organic contaminants when colloids (dissolved organic matter and bacteria) are present in the aquifer. A mathematical model for the transport of contaminants is developed and solved numerically for various situations. Results show that in the riverbank filtration the presence of DOM and bacteria enhances the mobility of contaminant significantly. Sensitivity analysis indicates that the distribution of the total aqueous Phase contaminant is significantly affected by distribution coefficients which account for affinity of solid or colloidal Phase to contaminant.

• 한국대기환경학회지
• /
• 제17권4호
• /
• pp.355-362
• /
• 2001

Adsorption isotherms of dichloromethane and 1, 1, 2-trichloro-1,2,2-trifluoroethane on an activated carbon pellet, Norit B4, were studied. For these chemicals, Sips equation gave the best fit for the single component adsorption isotherm. The adsorption affinity on activated carbon was greater for dichloromethane than that of 1, 1, 2-trichloro-1,2,2-trifluoroethane. An experimental and theoretical study was made for the adsorption of dichloromethane and 1, 1,2-trichloro-1,2,2-trifluoroethane in a fixed bed. Experimental results were used to examine the effect of operation variables, such as feed concentration, flow rate and bed height. Intraparticle diffusion was able to be explained by surface diffusion mechanism. An adsorption model baked on the linear driving force approximation (LDFA) was found to be applicable to fit the experimental data.

• Journal of Microbiology and Biotechnology
• /
• 제13권6호
• /
• pp.989-992
• /
• 2003

Recombinant human tissue plasminogen activator deletion mutein (Reteplase) is a clinically promising thrombolytic drug. Reteplase cDNA was subcloned into a bacteria expression system, and the resultant recombinant was biologically characterized. The Reteplase was expressed in Escherichia coli as an inclusion body, and the downstream processes of the Reteplase inclusion body included denaturation, renaturation, and purification. A protein disulfide isomerase (PDI) was used to assist the refolding of Reteplase, and it was found to increase the refolding rate from less than 2％ to more than 20％. The refolded Reteplase was purified through two chromatography steps, including lysine-coupled agarose affinity chromatography and then CM-sepharose cation-exchange chomatography. The purity of r-PA was analyzed by Western bolt analysis, and N-terminal amino acid and amino acid composition analyses confirmed the end-product. Reteplase showed higher thrombolytic potency in an animal thrombus model.

• 한국정보과학회:학술대회논문집
• /
• 한국정보과학회 2008년도 한국컴퓨터종합학술대회논문집 Vol.35 No.1 (B)
• /
• pp.346-350
• /
• 2008

AMD에서 사용한 HyperTransport 기술 기반 다중 처리기가 좋은 성능을 보이면서 최근 NUMA(Non Uniform Memory Access) 환경에 대한 관심이 증가하고 있다. 본 논문에서는 NUMA 시스템을 위한 부하균등 모델을 제안한다. 다중 처리기 시스템에서 운영체제는 특정 처리기에 부하가 많아지는 것을 부하가적은 처리기로 나누어 주기 위해 부하 균등 기법들을 가지고 있다. 이런 부하 균등 기법은 처리기가 가지고 있는 태스크 개수에 의존적인 연구가 많다. 본 연구에서는 NUMA 시스템의 메모리 접근 비용이 위치에 따라 다른 것을 반영한 부하 균등 기법의 모델을 제시한다. 이를 위해 모의 실험 환경을 구축하고 특정 상황들에 대한 실험을 통해 증명한다.

• Tribology and Lubricants
• /
• 제19권5호
• /
• pp.245-250
• /
• 2003

Water is known to playa crucial role on friction of moving parts in nanoscale contact. Little is, however, known about the tribological behavior of a solid surface that is covered with water adsorption layer. The objective of this study is to investigate the nanotribological behavior of the water layer in relation to water affinity of the surface and relative humidity. This paper presents an examination of the frictional behavior of water adsorption layer as 'confined liquid film'. It is shown that the friction is inversely proportional to the hydrophilicity of surface and relative humidity. On the other hand, friction of hydrophobic surface is not influenced by relative humidity. A model is proposed for the water-mediated contact in which it is shown that the water layer between two hydrophilic surfaces with high relative humidity behaves as a lubricant.

• Bulletin of the Korean Chemical Society
• /
• 제26권4호
• /
• pp.585-588
• /
• 2005

Bipyridine and its derivatives have been widely used as the ligands in transition metal complexes. The proton affinities of pyridine derivatives were calculated using an ab initio quantum mechanical method (B3LYP with various double zeta and triple zeta basis sets) in combination with the Poisson-Boltzmann continuum solvation model. Van der Waals radii of the atoms in the heterocyclic rings for the solvation energy calculation were set to values determined to reproduce the $pK_a$ values of guanine and oxoguanine derivatives and that of chlorine was optimized to reproduce the experimental values of relating compounds. The $pK_a$ values for the heterocyclic ring compounds were in agreement with the experimental values with a mean unsigned error of 0.45 $pK_a$ units.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• 제8권7호
• /
• pp.2400-2419
• /
• 2014

Pre-segmented pixels can reduce the difficulty of segmentation and promote the segmentation performance. This paper proposes a novel segmentation method based on merging texture superpixels by computing inner similarity. Firstly, we design a set of Gabor filters to compute the amplitude responses of original image and compute the texture map by a salience model. Secondly, we employ the simple clustering to extract superpixles by affinity of color, coordinates and texture map. Then, we design a normalized histograms descriptor for superpixels integrated color and texture information of inner pixels. To obtain the final segmentation result, all adjacent superpixels are merged by the homogeneity comparison of normalized color-texture features until the stop criteria is satisfied. The experiments are conducted on natural scene images and synthesis texture images demonstrate that the proposed segmentation algorithm can achieve ideal segmentation on complex texture regions.

• Macromolecular Research
• /
• 제10권1호
• /
• pp.18-23
• /
• 2002

We theoretically consider blends of two monodisperse one-end-functionalized homopolymers (denoted by A and B) capable of forming clusters between functional groups (stickers) using weak segregation theory. In this model system resulting molecular architectures via clustering resemble star copolymers having many A- and B-arms. Minimizing the total free energy with respect the cluster distribution, the equilibrium distribution of clusters is obtained and used for RPA (Random Phase Approximation) equations as input. For the case that polymers are functionalized by only one kind of sticker, the phase diagrams show that the associations promote the macrophase separation. When there is strong affinity between stickers belonging to the different polymer species, on the other hand, the phase diagram show a suppression of the macrophase separation at the range of high temperature regime, as well as the phase coexistence between a disordered and a mesoscopic phase at the relatively lower temperatures.

• Journal of Industrial and Engineering Chemistry
• /
• 제68권
• /
• pp.220-228
• /
• 2018

In this study, we found a simple surface biofunctionalization of biphasic calcium phosphate (BCP) based on the high affinity between alendronate and the calcium ions of BCP, and the strong interaction between heparin and bone morphogenic protein-2 (BMP-2). The biofunctionalized BCP did not be precipitated well and display a remarkable enhancement of osteogenic activity of human adipose-derived stem cells by showing increased alkaline phosphatase (ALP), calcium deposition and osteogenic-related genes (i.e., Runx-2, ALP, osteocalcin, and osteopontin), and bone regeneration in the calvarial defect model. Therefore, this simple surface technique can be used to easily functionalize various calcium phosphates.

• Bulletin of the Korean Chemical Society
• /
• 제33권5호
• /
• pp.1475-1479
• /
• 2012

Human peroxisome proliferator-activated receptor gamma ($hPPAR{\gamma}$) has been implicated in numerous pathologies, including obesity, diabetes, and cancer. In this study, we verified that amentoflavone is an agonist of $hPPAR{\gamma}$ and probed the molecular basis of its action. It was demonstrated that amentoflavone bound $hPPAR{\gamma}$ with high (picomolar) affinity and increased the binding between $hPPAR{\gamma}$ and steroid receptor coactivator-1 (SRC-1) by approximately 4-fold. Based on a docking study, for the first time, we propose a model of amentoflavone and $hPPAR{\gamma}$ binding in which amentoflavone forms three hydrogen bonds with the side chains of His323, Tyr327, and Arg280 in $hPPAR{\gamma}$ and participates in two hydrophobic interactions.