• 임상간호연구
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• 제20권1호
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• pp.75-89
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• 2014

Purpose: This study was done to identify conditions of cancer patients who visited an emergency department (ED) with the side effects of chemotherapy. Methods: Data were collected retrospectively from medical records of 294 cancer patients who visited a tertiary hospital in 2009 for treatment of side effects of chemotherapy. Records were reviewed for characteristics of participants and side effects of chemotherapy. Data were analyzed using SPSS software. Results: ED Triage grade 3 was 81.6%. The hospitalization ratio was 72.8%, and 6.5% died during the admission. Most frequent side effects were thrombocytopenia (80.6%), anemia (74.5%), pain (52.0%), neutropenia (50.7%), and leucopenia (46.3%). The hospitalization group showed more severe leucopenia than the discharge group (p=.020). Patients in the group who died had higher scores for dyspnea compared to patients discharged or hospitalized (p<.05). Conclusion: Results of the study suggest that there is a special need to develop a system to manage side effects of chemotherapy. Also it is necessary to provide appropriate care and treatment with prompt initial evaluation when cancer patients with side effects of chemotherapy present in the ED. More effective educational discharge programs should also be developed to help these patients cope with various side effects of chemotherapy.

• 대한치과보철학회지
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• 제50권4호
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• pp.311-317
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• 2012

총의치 장착시, 환자는 생리적으로 안정된 범위 내에서 자연스럽게 기능하기를 원하며 이를 위해서는, 안모의 회복(심미적 효과), 생물학적으로 안정된 인공치 배열과 외형, 의치 동요가 없는 교합접촉이 반드시 필요하다. 이에 본 증례보고에서는 총의치를 제작하기에 불리한 조건을 가진 환자를 대상으로 인상면, 연마면, 교합면에 있어서의 의치의 안정을 증대시키기 위해, 기능적 변연 형성을 통한 인상채득, 중립대 확인, 생리적 중심위 재확립, 안정된 교합을 형성시켜 주었으며, 임상적으로 기능과 심미적인 측면에 있어서 만족할 만한 결과를 얻었기에 이를 보고하고자 한다.

• BMB Reports
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• 제51권1호
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• pp.45-53
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• 2018

Mammalian target of rapamycin complex 1 (mTORC1) plays a major role in cell growth, proliferation, polarity, differentiation, development, and controls transitioning between anabolic and catabolic states of the cell. It collects almost all extracellular and intracellular signals from growth factors, nutrients, and maintains cellular homeostasis, and is involved in several pathological conditions including, neurodegeneration, Type 2 diabetes (T2D), obesity, and cancer. In this review, we summarize current knowledge of upstream signaling of mTORC1 to explain etiology of T2D and hypertriglyceridemia, in which state, the role of telomere attrition is explained. We discuss if chronic inhibition of mTORC1 can reverse adverse effects resulting from hyperactivation. In conclusion, we suggest the regulatory roles of telomerase (TERT) and hexokinase II (HKII) on mTORC1 as possible remedies to treat hyperactivation. The former inhibits mTORC1 under nutrient-rich while the latter under starved condition. We provide an idea of TOS (TOR signaling) motifs that can be used for regulation of mTORC1.

• 한국기계가공학회지
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• 제16권5호
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• pp.78-84
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• 2017

Compared to other types of power, hydraulic energy is the most commonly used for heavy vehicles and ships because it has fewer location and space constraints, and its controllability can be maintained even under adverse conditions. Operators have controlled a main control valve of ship winches by pushing or pulling the lever, which is directly connected to the spool. However, because of the spatial arrangement, the importance of remote control valves has emerged. In this paper, experiments of the hysteresis characteristics were performed by analyzing the remote-control valve using a valve tester and RA2300. The validity was verified by comparing with the analytical model using SimulationX as the hydraulic analysis program. This study examined the effects of the spool's notch (Non, End-mill, and Spherical) and the effects of stiffness and pre-load of the spool spring on Spool stroke, open area, and hysteresis characteristics. It is considered possible to reduce the cost and the, trial and error process in designing remote-control valves in the future.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1998년도 제13차 학술회의논문집
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• pp.391-394
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• 1998

The man-machine interface Is an important factor in the computer system, and it is thought that line-of-sight (LOS) detection technology will allow significant advances in this field. Techniques for detecting LOS for use in human interfaces have been studied［1]［2］. In earlier studies, however, LOS was detected with a head piece, goggles, or through fixing the position of the head. The limitations imposed by these fixed conditions render them unsuitable far use in interfaces, as they have adverse mental or physical effects on humans. Therefore. they have not been sufficiently developed for practical application. Research on non-contact LOS detection is expected to result in a usable LOS man-machine interface［3］［4］, and the current study is intended to be a step in that direction. The authors used color contact lenses for LOS detection, and applied this new method to a computer interface. The use of color contact lenses simplifies image processing. The algorithm used in this study is sufficiently accurate for practical applications. This technique can be used in input devices, in virtual reality applications, and in human engineering research.

• 한국환경농학회:학술대회논문집
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• 한국환경농학회 2011년도 30주년 정기총회 및 국제심포지엄
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• pp.196-204
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• 2011

Abiotic stress is the primary cause of crop loss worldwide, reducing average yields for most major crop plants by more than 50%. In addition, future agricultural production and management will encounter multifaceted challenges from global climate change. Therefore, it is necessary to study the molecular response of crop plants to the stresses in order to develop appropriate strategies to sustain food production under adverse environmental conditions. We carried out a large scale proteomic analysis of soybean plants in response to various abiotic stresses, including drought, salinity, waterlogging and their interactions. Proteins were analyzed by two dimensional polyacrylamide gel electrophoresis followed by matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry. The identified proteins are involved in a wide range of cellular functions. In addition to the well known stress-associated proteins, we identified several novel proteins, which were not reported before. In many cases our proteomic data bridges the gap between mRNA and metabolite data. Our studie provides new insights into identification of abiotic stress responsive proteins in soybean, and demonstrates the advantages of proteomic analysis in dissecting metabolic and regulatory networks.

• Weed & Turfgrass Science
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• 제2권2호
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• pp.164-169
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• 2013

Alternatives to commercial chemical herbicide are currently being searched and tested due to the numerous adverse effects of commercially available herbicides to the environment. Barnyardgrass (Echinochloa crusgalli) is an important weed species around the world, especially in paddy rice fields. This study focuses on the favorable effects of mixing pyroligneous acids with commercial liquid herbicides. Seedlings were transplanted and grown under greenhouse conditions. The effect of treatment time or leaf-stage on herbicide-pyroligneous acid efficacies was checked, coupled with isolation and quantification of biochemical compounds. Results revealed that herbicide treatment at early post emergence (2~3 leaf stage) of Echnochloa crus-galli leads to effective control. Both liquid herbicides affected fatty acid, protein, and amino acid syntheses as reflected on their contents. The influence of wood vinegar (WV) or rice vinegar (RV) on these compounds was not thoroughly verified due to lack of information on the pyroligneous products. We observed that mixing WV or RV with BCB (bentazone + cyhalof-butyl) gives more favorable results than BUC (butachlor + clomazone), mixed with WV or RV. The result would indicate the potential of mixing pyroligneous acid in reducing herbicide application rate.

• Journal of Dental Anesthesia and Pain Medicine
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• 제17권4호
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• pp.323-327
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• 2017

QT prolongation is an electrocardiographic change that can lead to lethal arrhythmia. Acquired QT prolongation is known to be caused by drugs and electrolyte abnormalities. We report three cases in which the prolonged QT interval was improved at the time of operation by briefly discontinuing the drugs suspected to have caused the QT prolongation observed on preoperative electrocardiography. The QTc of cases 1, 2, and 3 improved from 518 to 429 ms, 463 to 441 ms, and 473 to 443 ms on discontinuing the use of a gastrointestinal prokinetic agent, a proton pump inhibitor, and a molecular targeted drug, respectively. These cases were considered to have drug-induced QT prolongation. We reaffirmed that even drugs administered for conditions unrelated to cardiac diseases can have adverse side effect of QT prolongation. In conclusion, our cases indicate that dental surgeons should be aware of the dangerous and even potentially lethal side effects of QT prolongation. For safe oral and maxillofacial surgery, cooperation with medical departments in various fields is important.

• 비교문화연구
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• 제27권
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• pp.123-143
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• 2012

China's Yueyanglou(岳陽樓) cultural landscape and cultural landscape of Korea, respectively Yueyanglou(岳陽樓) investigated and the following results were extracted. First, multi-cultural personalities to ever Yueyanglou(岳陽樓) China's outstanding natural beauty around the emotion of his drawing on the literature and a new cultural landscape was formed. Their main feeling of the beauty of nature through his ash under adverse conditions up again in politics, which expresses the desire to advance. To this end, his outlook on life and also an attitude overhaul yeotboinda. This information formed the cultural landscape of Korea Yueyanglou(岳陽樓) not deviate from that has been investigated. Second, Korea is entirely China's 'sun' Lou Yueyanglou(岳陽樓) was a significant effect of cultural landscape. The beautiful landscapes of the Joseon Dynasty literati in the Joseon reported only in words and pictures they admired China's leading natural and cultural landscape and paste the name of the famous' sun Lou watch it was transformed into a cultural landscape. For this reason, the current remaining two 'sun' Lou, but probably the Joseon Dynasty, called the 'sun tower base and is estimated to be more common than now. In addition, in Hadong Yueyanglou(岳陽樓) near the sun 'Lou, China has also attached near the nomination could be an important clue.

• 국제초고층학회논문집
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• 제8권4호
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• pp.235-253
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• 2019

This paper reviews shape optimization studies for tall and super-tall building design. Firstly, shape effects on aerodynamic and response characteristics are introduced and discussed. Effects of various configurations such as corner modifications, taper, setback, openings, and twists are examined. Comprehensive comparative studies on various configurations including polygon building models, and composite type building models such as corner-cut and taper, corner-cut and taper and helical, and so on, are also discussed under the conditions of the same height and volume. Aerodynamic characteristics are improved by increasing the twist angle of helical buildings and increasing the number of sides of polygon buildings, but a twist angle of $180^{\circ}$ and a number of sides of 5 (pentagon) seem to be enough. The majority of examined configurations show better aerodynamic characteristics than straight-square. In particular, composite type buildings and helical polygon buildings show significant improvement. Next, shape effects on pedestrian-level wind characteristics around tall and super-tall buildings are introduced and discussed. Corner modification buildings show significant reductions in speed-up areas. On the other hand, setback and tapered models with wider projected widths near the ground show adverse effects on pedestrian-level wind characteristics.