• The korean journal of orthodontics
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• v.24 no.2
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• pp.331-348
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• 1994

The purpose of this study was to investigate changes in the shape and ultrastructure of the articular disc of the rat mandibular joint with aging. Mechanical stress applied to the articular disc changes during neonatal, suckling, juvenile, adult and senile stages. Mandibular joints of 6 groups of rats(1-, 7-, 17-, 27-, 55-day and over-1-year groups) were removed en bloc and processed for light and electro microscopic study. The changes in the shape of articular disc were examined by light microscope in each group. Structural and ultrastructural changes in the articular disc were examined by light and electron microscope in each group. The results were as follows : In the 1-day and 7-day groups, the articular disc was long and slender in shape and the articular disc was not fitted with the shape of the mandibular fossa and condyle. However' after that time, the anterior and posterior portions of the articular disc were more bulged and the middle portion was shorter and biconcave. Thus the articular disc was well fitted with the shape of the mandibular fossa and condyle. The cell density decreased with aging. In the l -day and 7-day groups, the Golgi apparatus, rough endoplasmic reticulum and free ribosome, which are involved in the synthesis of intracellular and extracellular matrix, were developed. In the 17-day, 27-day and 55-day groups, not only the cell organelles involved in the synthesis of the intracellular and extracellular matrix but also the cell organelles involved in the remodeling of the extracellular matrix(i.e., finger-like cell process, lysosome and mitochondria)were well developed. With advancing age, intracytoplasmic microfilaments were more accumulated and condroid cells increased. In the over-1-year group, the majority of cells of the articular disc were chondroid cells. The majority of cytoplasmic compartment were filled with intracytoplasmic microfilaments and cell organelles were not developed. Therefore, metabolic activities of the cell was markedly reduced and cells contained structures enduring mechanical stress, and cells which were in the process of degeneration were observed occasionally.

• Journal of Information Technology Applications and Management
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• v.26 no.4
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• pp.51-69
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• 2019

One of the most considerate phenomena of the era of the Fourth Industrial Revolution is the use of digital devices. Digitalization is rapidly advancing through all areas of industry and life. Customer journey with digitalization is looking totally different from previous customer journey. The research targets were users of fashion, automobiles, cosmetics and online shopping malls. We analyzed 300 people for each valid questionnaire. The results of the study are as follows. First, it has been proven that digital experience affects positive (+) impact on purchasing intention and positive (+) impact on recommending intention and negative impact (-) on switching intent and subsequently affects positive impact (+) to purchase and incase of switching intent, negative impact (-) to purchase. Unlike traditional methods such as SPC(Service Profit Chain), the Digital experience to Purchase process Chain (DPC) has been identified to be suitable in the digital age. Second, the digital satisfied group (5 score-very satisfaction) has shown same result as above. However the digital neutral group (even though 4 score- satisfaction in five-point scale), specially in a highly competitive industry, has different from the satisfied group and 3 score-normal is same as dissatisfied group. It means that this group is that If there is a high level of attractiveness of substitute goods, there is a high possibility of switching them. It has supported Jones and Sasser [1995] that there have been two types of loyalty of true long-term loyalty and what we call false loyalty in the highly competitive industry zone which is commoditization or low differentiation, many substitutes, low cost of switching. Identifying true loyalty and false loyalty is crucial to establishing a customer experience strategy. it is necessary to actively utilize long-term digital experiences strategy to increase the total satisfaction of digital experience through all of customer purchasing journey in order to enhance the digital customer experience. It is difficult to see the effect as a one-time event. It should be scaled over the entire customer purchase process over a long period of time, which can positively affect purchase intention, recommendation intention, and conversion intention. This is also why it is difficult for second-runners to overtake first-runners in a short period.

• Journal of the East Asian Society of Dietary Life
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• v.18 no.5
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• pp.702-710
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• 2008

The principal objective of this study was to assess the effects of eating habits and health-related lifestyle on blood pressure, $\gamma$-Glutamic acid Peptide Transferase ($\gamma$-GPT), glucose and HDL-Cholesterol (HDL-C). All subjects (261 male, 252 female) were from the Iksan area of Korea, and were at least 50 years of age. The mean systolic blood pressure (SBP), diastolic blood pressure (DBP) and HDL-C for all the subjects was 131.3 mmHg, 78.5 mmHg, and 43.1 mg/dl, respectively. The HDL-C of the $50{\sim}64$ year-old group was higher than that of the over-75-year-old group. The "regular breakfast" group evidenced a lower SBP, $\gamma$-GPT, and higher HDL-C than the "seldom breakfast" group (p<0.001, p<0.001, p<0.01). SBP in the "snacking everyday" group was higher than that of the "seldom snacking" group (p<0.001). As for the frequency of using alcohol, SBP and $\gamma$-GPT for the group using alcohol everyday were higher than those of the non-drinking group (p<0.001, p<0.001), SBP and DBP were higher and $\gamma$-GPT was lower in the group that regularly drank more than 4 glasses of Soju than in the non-drinking group (p<0.001, p<0.05, p<0.001). SBP, DBP, and $\gamma$-GPT for the "heavy smoker" group were higher than those of the non-smoker group (p<0.01, p<0.01, p<0.05). The HDL-C was lower in the "heavy smoker" group than in the "non-smoker" group (p<0.05). The SBP with exercise was as follows: Group 1 ($0.022{\sim}0.073\;kcal/min/kg$) was lower than that of Group 3 ($0.144{\sim}0.161\;kcal/min/kg$) and Group 4 (0.161 kcal/min/kg) (p<0.001). To conclude: advancing age, snacking, and frequent alcohol consumption increased blood pressure; the lowest blood pressure was detected in the group that ate breakfast everyday and in the group that engaged in more frequent exercise; Moreover, $\gamma$-GPT was higher and HDL-C was lower in the smokers' group than in the non-smokers' group. Considering the results of this study, there appears to be an urgent need to instruct aging adults about eating breakfast everyday, reducing smoking, using less or no alcohol, and getting proper and regular exercise.

• International Commerce and Information Review
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• v.16 no.2
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• pp.297-318
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• 2014

The study has try to analyze firm-level marketing strategy for making inroads into United Arab Emirate(UAE) in the Middle East Rrgion. Korea's pharmaceutical medicine industry can overcome that growth limit by strategically advancing into the world market even the its market share is slight as of 2013. The results of Marketing Mix strategies to enter the UAE pharmaceutical medicine market are as follows: STP strategy and Marketing Mix strategy based on the findings of this study, the practical implications of the following. First of all, domestic pharmaceutical industries in Korea due to the domestic market, growth in the various institutional devices have limits on the expansion. On the other hand, supports the Government's active policy of UAE health care industry is booming. UAE Government medical facilities and health care in the health care industry in 2010 to improve the level of 80 billion dollars of investment. The UAE's medical sector is equipped with independent regulatory regime by the Emirates. The UAE is a foreign worker influx has been showing a high population growth rate, over the last 30 years, UAE resident population has increased about 7 times. The UAE Government to improve the quality of medical services, the private sector and the public to encourage the signing of partnership (PPP) can also be found in the regulation of foreign direct investment. The results of this study would play a role in analyzing a marketing strategy to make inroads into UAE pharmaceutical medicine market.

• Journal of the Korean Society of Marine Environment & Safety
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• v.19 no.5
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• pp.525-530
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• 2013

In this study, the generator engine of training ship M/S "HAE RIM" of Kunsan National University which is being operated for 20 years was used in the experiment. The experiment was carried out under the engine speed of 1200rpm, then the load was varied 30 kW intervals from 0 to 90 kW and the injection timing was varied $2^{\circ}$CA intervals from BTDC $19^{\circ}$ to $23^{\circ}$CA. In the case of advancing fuel injection timing from BTDC $21^{\circ}$CA to $23^{\circ}$CA, specific fuel consumption is decreased by 1.37%, NOx is increased by 11.59 %, soot is decreased by 23.5 % and $SO_2$ is decreased by 2.8 %. Accoring to the analysis of effects of fuel injection timing on combustion & exhaust emissions characteristics on an old marine diesel engine, it is proved that the optimum fuel injection timing is BTDC $23^{\circ}$ which is $2^{\circ}$ faster than that of original injection timing.

• YAKHAK HOEJI
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• v.55 no.5
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• pp.411-418
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• 2011

The dissolution test method and an analytical procedure by HPLC were developed and validated for nafronyl oxalate capsules and tramadol hydrochloride capsules. These drugs were not yet characterized by the dissolution specifications in the Korean Pharmaceutical Codex. So, with each reference and test drugs, we did the preliminary and standard experiments based on the Korean Pharmacopeia Guideline of dissolution testing for solid oral dosage forms. The dissolution test for nafronyl oxalate capsules was carried out under sink conditions as follows: dissolution medium phosphate buffer pH 6.8, paddle rotation speed 100 rpm and vessel volume 900 ml. More than 80% of its label amount was released within 30 min in this method. Also the dissolution test for tramadol hydrochloride capsules was carried out under sink conditions as follows: dissolution medium water, paddle rotation speed 50 rpm and vessel volume 900 ml. More than 90% of its label amount was released within 15 min in this method. The dissolution samples were analyzed with a validated HPLC analytical procedure. The analytical methodology showed acceptable values in terms of specificity, linearity, precision and accuracy. The dissolution test methods described above were adequate for the purpose and may be proposed as a pharmacopeial standard to assess the performance of nafronyl oxalate capsules and tramadol hydrochloride capsules. Furthermore, the outcomes of this study were expected to help create an environment where safe and high quality drugs would be distributed on the domestic market making contributions to advancing public health.

• Journal of The Korean Society of Grassland and Forage Science
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• v.29 no.2
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• pp.129-136
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• 2009

This study was to optimize the harvest time of several winter cereal forage crops. Barley, rye, oat, triticale and wheat were evaluated for the quantity and quality of hay and silage at four different harvesting stages, including heading, 10 days after heading (DAH), 20 DAH and 30 DAH. Barley and wheat harvested at 20 DAH, and oat and triticale at 30 DAH showed maximum dry matter yield. Crude protein content of barley, wheat, triticale and oat decreased significantly with advancing crop maturity. Mean crude protein content was the highest in rye and the lowest in oat. The NDF and ADF content of barley, wheat, triticale and oat decreased with late harvest, while rye increased. Maximum total digestible nutrients (TDN) content was recorded in barley and wheat harvested at 20 DAH, in triticale and oat at 30 DAH, and in rye at heading. The maximum TDN content of silage, 66.98%, was recorded in barley, followed by wheat, triticale, oat and rye. However, The crude protein, NDF and ADF of silage was 1 to 4 times higher than those of hay. In this study, barley harvested at 20-25 DAH, wheat and triticale at 30 DAH, and rye at heading provided a good compromise between dry matter yield and forage quality. At this stage, a sufficient quantity of fodder with moderate forage quality was obtained.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2002.11a
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• pp.301-306
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• 2002

In Japan, the vacancy rates of office buildings have been at high in big cities since 1992. This problem is especially acute in Tokyo, where it is estimated that over 2.27 million square meters of office floor area will be oversupplied in 2003: big urban redevelopment projects will be completed in 2003. Under these circumstances, International Cooperative Research and Development on Sustainable Urban Management by Conversion of Buildings, called “SUMCOB”, has been carried out. This research aims to regenerate urban areas by converting redundant offices into flats, although instances of conversion are still very few in Japan. This paper introduces part of current results by SUMCOB, and discusses legal problems with conversion and basic capacity of vacant offices in Tokyo. It has been confirmed that there are no constraints concerned with Real Estate Registration Law (although it requires the change of the registration after conversion). and City Planning Law. However, some criteria are incompatible with Building Standard Law and Fire Service Law if the use of the building is changed from offices to flats. Typical incompatibility between offices and flats is lightening. If the buildings do not satisfy criteria for flats, the cost of renovation works for conversion will increase. To examine the basic capacity of vacant office buildings for conversion, field surveys in Tokyo have carried out at three areas: Kodenmacho (Chuo-ku), Toranomon (Minato-ku), and Iwamonocho (Chiyoda-ku). They are typical office areas that are included in center core of Tokyo. In Chuo-ku, the oldest commercial area in Tokyo, textile merchants have been located their headquarters. In Minato-ku, many rental office buildings have been located and several large scale redevelopments are advancing. Chiyoda-ku includes Marunouchi area, which is the prime office area in Japan. Thirty percent of the buildings in survey areas suffer from over twenty percent vacant floor rate, and fifty five percent were constructed before 1990. Especially most of buildings over forty percent vacant floor rate were constructed in 1980s. Vacant office problems haven't been seen in old buildings in Tokyo yet. The number of dwelling units made from office space will influence the conversion scheme. Seventy percent of the office buildings in survey areas have floor area of less than two hundred square meters. If they have been subdivided into two bedrooms type or three bedrooms type, the number of dwelling units in a floor would be less than three. The difficulty of conversion planning derives from frontage size, depth size, and their proportion. The five categories are proposed to grasp actual requirements for converting offices into flats.

• Journal of the Economic Geographical Society of Korea
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• v.23 no.2
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• pp.147-165
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• 2020

The aim of this study is to find out Korean electronic industries' production network in Hanoi Red River Delta, Vietnam and its change based on customer-following overseas expansion. In-depth interviews with Korean subcontractors were conducted to examine the characteristics of customer-following overseas expansion of Korean subcontractors. Korean subcontracting corporations in electronic industries have expanded into Vietnam as the suppliers to Korean transnational corporations. Since 1990s, Korean corporations have invested into Vietnam but since late 2000s its industrial and geographical concentration has been shifted from textile and clothing industries in Southern Vietnam to electronics in Northern Vietnam. The customer-following overseas expansion of the subcontractors has emerged in three aspects: physical proximity, asymmetrical inter-firm relations and organizational embeddedness. During the process of customer-following overseas expansion, Korean electronic industry production network was transplanted into Vietnam and partially modified. This is because the company's hierarchy and difficulties in changing its trading relationship have affected the process of advancing into overseas markets. Korean transnational corporations seek to establish a stable suppliers through expansion accompanying with its subcontractors, and providing financial and non-financial support to its subcontractors.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1513-1520
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• 2009

The purpose of this study was to compare cerebral blood flow between hyperlipidemic patient group and normal healthy aldult group using transcranial doppler ultrasonography(TCD). I investigated cerebral blood flow of 63 hyperlipidemic patients and 42 healthy adults. To evaluate the cerebral blood flow, I measured the systolic peak velocity(Vs) and mean flow velocity(Vm) of the milddle cerebral artery(MCA), anterior cerebral artery(ACA), posterior cerebral artery(PCA), basilar artery(BA), internal carotid artery(ICA) in the two groups using TCD. In normal healthy adults, subjects showed a decerease in Vs and Vm with advancing in age. There was a significant difference in the Vm of ICA. There was no significant differences in the Vm of ACA and ICA. In normal healthy adults, females showed high velocities of all examined vessel. There was a significant difference in the Vs of ICA. There was a significant differences in the Vm of MCA and ICA. Normal healthy adults higher than hyperlipidemic patients in the Vs of MCA, ACA, PCA. There was no significant difference in the Vs of all exmined vessels. Hyperlipidemic patientsincrease higher than normal healthy adults in the Vm of ACA. There was a significant difference in the Vs of BA. In the patients aged under 50's, normal healthy adults higher than hyperlipidemic patients in the Vs and Vm except BA. But there was no significant difference in all exmined vessels. In the patients aged over 50's, hyperlipidemic patients higher than normal healthy adults in all examined vessel expect PCA. There was a significant difference in the Vs of BA and ICA. And hyperlipidemic patients higher than that normal healthy adults in all exmined vessels. There was a significant difference in BA and ICA. In this study, visible differences in blood flow between hyperlipidemic patient group and normal healthy aldult group were shown. However, these results do not come up to the previous values that were reported and known worldwide.