• 제목/요약/키워드: Advanced level

검색결과 3,911건 처리시간 0.035초

N-methyl-N'-nitro-N-nitrosoguanidine Reduces the Intracellular Calcium Level Through NAD Depletion in NIH3T3 Cells

  • Yoon, Yoo-Sik;Shin, In-Cheol;Kim, Jin-Woo;Kang, Ke-Won;Joe, Cheol-O
    • BMB Reports
    • /
    • 제28권5호
    • /
    • pp.392-397
    • /
    • 1995
  • The effect of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) on the intracellular $Ca^{2+}$ level was studied in NIH3T3 fibroblast cells. A reduction of the intracellular $Ca^{2+}$ level was observed after exposure to 300 ${\mu}m$ MNNG. However, the intracellular level of $IP_3$, a well-known regulator of $Ca^{2+}$ release from internal storage, was not changed by MNNG treatment. Instead, a reduction of the intracellular NAD level was observed. NAD as well as $IP_3$ stimulated intracellular $Ca^{2+}$ release from permeabilized cells. The treatment of 3-aminobenzamide, which inhibited the MNNG-induced reduction of the NAD level, also prevented the MNNG-induced decrease of the $Ca^{2+}$ level. Our data suggest that MNNG reduces the intracellular $Ca^{2+}$ level by NAD depletion in NIH3T3 cells.

  • PDF

연속식 가열로의 Level 2 제어 시스템 설계 (Design of Level 2 Control System for Continuous Reheat Furnaces)

  • 유보현;이재용;임동렬;차재민;염충섭
    • 시스템엔지니어링학술지
    • /
    • 제12권1호
    • /
    • pp.113-120
    • /
    • 2016
  • Steel in a continuous reheat furnace is heated to higher temperature to be treated in the rolling steel process. Due to this reason the continuous reheat furnace system requires an optimal control system to adjust the temperature inside the furnace. Level 2 control systems for continuous reheat furnaces generate automatic heating set points for the level 1 system of the furnace based on the mathematical thermal model which can give a good estimation of steel heating inside the furnace and is used to adjust heating requirements to optimize furnace combustion. For the current study the analytic methodology based on the design procedure from the systems engineering to develop new level 2 control system of a continuous reheat furnace was proposed. The system analysis and the requirements of the level 2 control system were derived using the unified modeling language (UML) 2.0, and the design of database and the graphic user interface (GUI) for the level 2 control system were conducted.

AVERAGE LIQUID LEVEL AND PRESSURE DROP FOR COUNTERCURRENT STRATIFIED TWO-PHASE FLOW

  • Kim, Yang-Seok;Yu, Seon-Oh;Chun, Moon-Hyun
    • 한국원자력학회:학술대회논문집
    • /
    • 한국원자력학회 1996년도 추계학술발표회논문집(1)
    • /
    • pp.301-306
    • /
    • 1996
  • To predict the average liquid level under the condition of the countercurrent stratified two-phase flow in a pipe, an analytical model has been suggested. This is made by introducing the interfacial level gradient into the liquid-phase and the gas-phase momentum equations. The analytical method for the gas-phase pressure drop calculation with f$_i$ $\neq$ f$_G$ has also been described using the liquid level prediction model developed in the present study.

  • PDF

종양전문간호사인력 수요추계에 관한 연구 (A Study on the Projected Workforce of Advanced Oncology Certified Nurses)

  • 황성호;오복자
    • 종양간호연구
    • /
    • 제4권1호
    • /
    • pp.49-61
    • /
    • 2004
  • Purpose: The purpose of this study was to suggest the projected manpower of oncology nurses & Advanced oncology certified nurses needed in the future. Method: Need models, ratio models and expert opinion were used for projecting the number of oncology nurses & Advanced oncology certified nurses. Resul: 1. The demand for the oncology nurses was estimated 6,043 in the year 2003, 6,548 in the year 2005, and 4,556 in the year 2010. 2. The demand range of the advanced oncology certified nurses centering on the number of hospitalized patients were estimated 358-538 in the year 2003, 388-583 in the year 2005, and 448-672 in the year 2010. 3. The demand range of the middle and long term advanced oncology certified nurses centering on the number of sickbed were estimated 507-787 in the year 2005, 523-810 in the year 2010, and 540-837 in the year 2020. 4. The demand range of the advanced oncology certified nurses centering on the number of organizations were estimated 374 in the year 2003, 399 in the year 2005, 410 in the year 2010. 5. The total demand range, concerning the numbers of hospitalized patients, hospital bed, and organizations are estimated 358-538 in the year 2003, 388-787 in the year 2005, 428-840 in the year 2010, and 540-837 in the year 2020. 6. In the demand of developed country's level oncology nurses are OCN's level 1,495, AOCN's level 102 in the year 2003, OCN's level 1,613, AOCN's level 111 in the year 2005, OCN's level 1,879, AOCN's level 128 in the year 2010 in case of the United States, and in case of Canada, 765 in the year 2003, 826 in the year 2005, and 956 in the year 2010.

  • PDF

다양한 방법으로 성장된 ZnO layer의 Deep level emission에 대한 비교 분석 (A comparative analysis of deep level emission in the ZnO layers deposited by various methods)

  • 안철현;김영이;김동찬;공보현;한원석;최미경;조형균;이종훈;김홍승
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2008년도 하계학술대회 논문집 Vol.9
    • /
    • pp.102-103
    • /
    • 2008
  • Magnetron Sputtering, MOCVD, Thermal Evaporation에 의해 성장된 ZnO layer에 대한 Dependency Temperature Photoluminescence (PL)를 이용하여 비교 분석을 통해 Deep level emission에 대해 연구하였다. Sputter에 의해 성장된 ZnO 박막은 Violet, Green, Orange-red 영역의 $Zn_i$, $V_o$, $O_i$의 defect에 의한 Deep level emission을 보였고, MOCVD에 의해 성장된 박막은 비교적 산소양이 낮은 성장 조건에서는 blue-green 영역에서, 산소양이 높은 조건에서의 박막은 Orange-red 영역의 Deep level emission을 보였다. Blue-green 영역에서의 emission은 온도가 증가함에 따라 다른 Barrier를 보였는데, 이는 $V_{Zn}$$V_o$에 의한 것임을 알 수 있었다. 한편, ZnO nanorods는 $V_o$에 의한 Green 영역에서의 Deep level emission을 보였다.

  • PDF

The Need for Level-based Criteria in the Assessment of Oral Proficiency

  • Kim, Hae-Young
    • 영어어문교육
    • /
    • 제15권2호
    • /
    • pp.169-184
    • /
    • 2009
  • The purpose of this study is to identify the most important factor(s) that contribute(s) to the overall oral proficiency and to examine whether the factor(s) play(s) a different role depending on the proficiency level of learners. Learners were divided into novice group and advanced group and were asked to produce an oral recording of a story based on a comic strip. The recordings were transcribed and graded by three raters. According to the results, the raters attained high inter-rater reliability when assessing advanced learners. However, the reliability level became considerably lower in the assessment of novice learners. The best predictor of oral proficiency among novice learners was sociolinguistic competence and fluency, while grammatical competence and fluency were the strongest predictors for advanced learners. The results suggest the need for a separate assessment tool for different proficiency levels and the need for a different focus in the classroom depending on the learners' proficiency level.

  • PDF

직렬 연결된 GTO로 구성된 멀티레벨 인버터에 적합한 새로운 회생 스너버에 관한 연구 (A Novel Regenerative Snubber suitable to Multi-Level Inverters with Series-Connected GTOs)

  • 채균;조국춘;정구호;류태하;조규형
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 1996년도 하계학술대회 논문집 A
    • /
    • pp.585-587
    • /
    • 1996
  • A simple regenerative snubber structure is proposed, which is applicable to multi-level inverter with series-connected GTOs for high power applications. The novel snubber structure can solve large energy loss problems and guarantee safe operation of power converter can be achieved. The proposed new snubber has the potential of high performance and high reliability and is particularly suitable to high power and multi-level application with series connected power devices. The snubber voltage and current waveforms are analized and shown the simulation and experimental results for a GTO 3-level inverter circuit with inductive load.

  • PDF

a- Si:H TFT Level Shifter with Reduced Number of Power

  • Jeong, Nam-Hyun;Chun, Young-Tea;Kim, Jung-Woo;Bae, Byung-Seong
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 한국정보디스플레이학회 2008년도 International Meeting on Information Display
    • /
    • pp.20-23
    • /
    • 2008
  • We proposed a-Si:H TFT (hydrogenated amorphous silicon thin film transistor) level shifter which reduced number of power sources. To reduce the number of power sources from four to two, modified bootstrapped inverter was used for the level shifter. The shift register was verified by PSPICE circuit simulation and fabricated. The fabricated level shifter successfully shifted low input (0 to 5 V) to high level output (-7 to 23 V).

  • PDF

선진국 제조기업의 신제품 성공요인에 관한 비교 연구: 다수준 접근 방식 (A comparison of new product success factors across advanced countries: A multi-level approach)

  • 이영우;조영삼
    • 지식경영연구
    • /
    • 제21권2호
    • /
    • pp.59-75
    • /
    • 2020
  • In this paper, we investigate the influence of factors on the firm, industry, and country levels on the new product development performance (NPD) of manufacturing firms in advanced economies. The resource-based view, industrial organization theory and institutional theory have established that firm-, industry- and country-level factors are all relevant for the NPD of firms. However, little is known about the relative importance of factors at the three different levels across countries, as prior studies on firms' NPD have focused on specific countries and levels of analysis. Our analysis of survey data from 1,437 manufacturing firms in nine advanced OECD countries shows that while firm-level factors are generally better predictors of firms' innovativeness than either industry- or country-level factors, the results strongly differ across countries, indicating that the relative importance of antecedents of innovativeness is country-specific rather than universal.