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Study on the Removal of Pharmaceuticals and Personal Care Products and Microorganism Inactivation by Ozonation (오존처리에 의한 의약품류의 제거와 미생물의 불활성화에 대한 연구 및 고찰)

  • Kim, Il-Ho
    • Journal of Korean Society of Environmental Engineers
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    • v.32 no.12
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    • pp.1134-1140
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    • 2010
  • Ozonation is a promising process that can effectively reduce the occurrence of micropollutants and pathogen in water. This study investigated the performance of ozonation for the removal of pharmaceuticals and personal care products (PPCPs) in secondary effluent from wastewater treatment plant. Moreover, the disinfection potential of ozonation applied for PPCPs removal was discussed. Secondary effluent filtered by sand filter was used for tested water, and ozonation was performed under 2, 4 and 6 mg/L of ozone doses. As a result, 6 mg/L of ozone dose (ozone consumption : 4.4 mg/L) was essential for the effective removal of 37 PPCPs in tested water. Several previous studies showed that the operation condition could achieve approximately 3 log inactivation of total coliform and enteroviruses. On the other hand, dissolved ozone concentration in tested water increased by 1.8 mg/L under 6 mg/L of ozone dose, probably resulting in the increase of bromate formation potential. This result implies that as alternatives to suppress the bromate formation potential during the oxidation of PPCPs by ozone, investigations on advanced oxidation processes are required.

Distribution and Risk Assessment of Bisphenol-A in Tap Water from Rehabilitated Indoor Water Service Pipe (갱생 옥내급수관 수돗물에서 비스페놀-A 분포 및 위해성 평가)

  • Jeong, Gwanjo;Son, Boyoung;Lee, Inja;Ahn, Chihwa;Kim, Junil;Moon, Boram;Lee, Suwon;Ahn, Jaechan;Kim, Bogsoon;Chung, Deukmo
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.7
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    • pp.371-376
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    • 2016
  • In this study, the survey of bisphenol-A in indoor water service pipes rehabilitated with epoxy resin was conducted and the risk assessment was done to investigate the effect on the human health to drink tap water. Bisphenol-A in raw water was detected in a range of 50~118 ng/L in all samples, where the limit of quantification was 10 ng/L. This is caused by inflow of the sewage effluent or the tributaries of the surrounding area containing bisphenol-A. Bisphenol-A was not detected in finished water after the advanced water treatment process. It was achieved by its removal from the processes of flocculation-precipitation and oxidation of ozone and chlorine and by being changed to other by-product materials. For the indoor water service pipe, bisphenol-A was not detected in all cases which was not coated with epoxy resin. However, when epoxy resin is lined within the indoor water service pipe, bisphenol-A was identified at maximum level of 521 ng/L and was detected above the limit of quantitation at 68 percentages of all samples. The Hazard Quotient (HQ) at the maximum level (521 ng/L) of the detected bisphenol-A is 0.004, which is less than the reference value of 0.1 for the tap water intake. Therefore, it is considered that the detected levels of bisphenol-A in this study would be safe to drink tap water.

Studies on the Preservation of Korean Ginseng by Irradiation -Part II. Effect of Gamma Irradiation on the Physicochemical Properties of Ginseng Powder during the Storage- (방사선(放射線) 조사(照射)에 의(依)한 인삼저장(人蔘貯藏)에 관(關)한 연구(硏究) -제2보(第2報). 감마선(線) 조사(照射)가 인삼분말제품(人蔘粉末製品)의 저장중(貯藏中) 이화학적(理化學的) 특성(特性)에 미치는 영향-)

  • Sung, Hyun-Soon;Park, Myung-Han;Lee, Kwang-Seung;Cho, Han-Ok
    • Applied Biological Chemistry
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    • v.25 no.2
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    • pp.105-109
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    • 1982
  • The effect the physiochemical properties of red and white ginseng powder after $^{60}Co-{\gamma}$ ray irra diationduring the storage for 4 months at $25^{\circ}C$ was investigated. The storage periods and the treatment of irradation at various doses on ginseng powders has no significant effect on the proximate composition and color density of ginseng extract with 50% ethanol. No changes in the contents of saponin and its HPLC patterns were found during the storage. However, a little increase was found in the yield of 50% ethanol extract and Hunter's color value of powder. But generally it was found to be stable in the physicochemical properties of red and white ginseng powder by irradiation of the intensity during the storage.

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A Study on Improvement Plan for Selection of Evacuation Site through Analysis of Meteorological Data -Focus on Incheon·Siheung·Ansan- (기상관측자료 분석을 통한 위해관리계획 주민대피 장소 선정 개선방안 연구 -인천·시흥·안산 지역을 중심으로-)

  • Jeon, Byeong-Han;Kim, Hyun-Sub;Oh, Seung-Bo;Kim, Hee-Tae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.11
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    • pp.16-22
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    • 2017
  • This study examined the status of resident evacuation sites notified to nearby communities, centered on business sites subject to the risk management plan of Incheon, Siheung, and Ansan. Through an analysis of the meteorological data, the direction of improvement of the site selection process for the safe evacuation of chemical accidents was studied. Among a total of 111 evacuation sites, 30 schools were selected the most, and 2-3 sites were usually selected for evacuation. As a result of an analysis of the Incheon meteorological data of 2016, the frequency of occurrences was 18.8525% in the NNE wind direction, 18.0328% in the NNW wind direction, 12.2951% in the WSW wind direction, 9.0164% in the SSE direction, 8.4700% in the SW direction, 6.5574% in the W direction, and 5.7376% in the S direction. The NNE wind direction showed the highest frequency, but the other winds showed a relatively high frequency, indicating that the annual wind direction was not biased toward one side.

A Financial Comparison of Corporate Research & Development (R&D) Determinants: The United States and The Republic of Korea (한국과 미국 자본시장에서의 연구개발비 비중에 관한 재무적 결정요인 분석)

  • Kim, Hanjoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.7
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    • pp.174-182
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    • 2018
  • Given the ongoing debate in many aspects of finance, more attention may need to focus on corporate R&D expenditures. This study empirically tests financial determinants of R&D expenditures for NYSE-listed and KOSPI-listed firms. Three major hypotheses were postulated to test for corporate R&D outlay. First, proposed variables such as one-year lagged R&D expenditures, market value based leverage, profitability and cash holdings showed significant influence on corporate R&D costs for the sample firms. Moreover, financial factors inclusive of squared one-year lagged R&D expenditures, the interaction effect between one-lagged R&D expenditures and high-growth firm, non-debt tax shield, Tobin's q and a dummy variable to explain differences in accounting treatment between the U.S. and Korea, revealed significant differences between the two samples. Finally, in the conditional quantile regression (CQR) analysis for the R&D-related variables in relation to corporate growth rate, it was found that the NYSE-listed firms had a statistically significant linkage between growth potential and one-year lagged R&D expenditures at lower quantile levels. This study may shed new light on identifying financial factors affecting differences between the U.S. market (as an advanced market) and the Korean market (as an emerging market) regarding the optimal level of R&D investments for shareholders.

Breast Cancer Characteristics and Survival Differences between Maori, Pacific and other New Zealand Women Included in the Quality Audit Program of Breast Surgeons of Australia and New Zealand

  • Campbell, Ian;Scott, Nina;Seneviratne, Sanjeewa;Kollias, James;Walters, David;Taylor, Corey;Roder, David
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.6
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    • pp.2465-2472
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    • 2015
  • Background: The Quality Audit (BQA) program of the Breast Surgeons of Australia and New Zealand (NZ) collects data on early female breast cancer and its treatment. BQA data covered approximately half all early breast cancers diagnosed in NZ during roll-out of the BQA program in 1998-2010. Coverage increased progressively to about 80% by 2008. This is the biggest NZ breast cancer database outside the NZ Cancer Registry and it includes cancer and clinical management data not collected by the Registry. We used these BQA data to compare socio-demographic and cancer characteristics and survivals by ethnicity. Materials and Methods: BQA data for 1998-2010 diagnoses were linked to NZ death records using the National Health Index (NHI) for linking. Live cases were followed up to December $31^{st}$ 2010. Socio-demographic and invasive cancer characteristics and disease-specific survivals were compared by ethnicity. Results: Five-year survivals were 87% for Maori, 84% for Pacific, 91% for other NZ cases and 90% overall. This compared with the 86% survival reported for all female breast cases covered by the NZ Cancer Registry which also included more advanced stages. Patterns of survival by clinical risk factors accorded with patterns expected from the scientific literature. Compared with Other cases, Maori and Pacific women were younger, came from more deprived areas, and had larger cancers with more ductal and fewer lobular histology types. Their cancers were also less likely to have a triple negative phenotype. More of the Pacific women had vascular invasion. Maori women were more likely to reside in areas more remote from regional cancer centres, whereas Pacific women generally lived closer to these centres than Other NZ cases. Conclusions: NZ BQA data indicate previously unreported differences in breast cancer biology by ethnicity. Maori and Pacific women had reduced breast cancer survival compared with Other NZ women, after adjusting for socio-demographic and cancer characteristics. The potential contributions to survival differences of variations in service access, timeliness and quality of care, need to be examined, along with effects of comorbidity and biological factors.

Effect on Smoking Quit Rate of Telling Smokers their Health Risk Appraisal in Terms of Health Age: A Randomized Control Trial

  • Paek, Yu-Jin;Lee, Sungkyu;Kim, Yun-Hee;Lee, Kang-Sook;Yim, Hyeon-Woo;Kim, Myung-Shig;Kim, Cheol-Hwan;Jeung, Ok
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.12
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    • pp.4963-4968
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    • 2014
  • Background: We evaluated whether providing health risk appraisal for Koreans (KHRA) in terms of 'health age' during smoking cessation program would effectively help smokers quit smoking or not. Materials and Methods: A total of 332 male smokers aged between 30-65 years old, registered for a smoking cessation program in a public health center in a city, were recruited and underwent a baseline survey from January 2010 to February 2011. They were then prospectively randomized to a conventional counseling group (n=165) or a KHRA group (n=167), and received conventional counseling or KHRA-based counseling for six months. Abstinence rates were identified through carbon monoxide measurement (at the $4^{th}$ and $24^{th}$ weeks) or urinary cotinine level (at the $12^th$ week). Results: The abstinence rate confirmed by exhaled carbon monoxide was significantly higher in the KHRA group (61.1%) than the control group (49.1%) at the $4^{th}$ week (absolute difference 12.0%, 95% CI: 1.4%-22.6%). However, there was no difference in abstinence rates between the two groups at the 12th and 24th weeks. The predicting factors of 24 week's smoking cessation success were age, older than 50 years old (OR 2.02, 95% CI: 1.16-3.52), lower Fagerstr$\ddot{o}$m Test for Nicotine Dependence score less than 4 (OR 1.84, 95% CI: 1.03-3.29), and higher Self Efficacy/Temptation score (OR 1.79, 95% CI: 1.05-3.06). Conclusions: Smoking cessation counseling with KHRA could be effective compared to conventional counseling in the short period of smoking cessation. Further study is needed to evaluate the long-term efficacy of KHRA in tobacco dependence treatment and to establish the indication and target population of this tool.

Management of Elderly Patients with Intracranial Aneurysm (고령군 뇌동맥류 환자의 치료)

  • Park, Hyeon Seon;Lee, Jae Whan;Kim, Jin Young;Shin, Yong Sam;Joo, Jin Yang;Huh, Seung Kon;Lee, Kyu Chang
    • Journal of Korean Neurosurgical Society
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    • v.29 no.6
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    • pp.786-793
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    • 2000
  • Objectives : A clinical analysis was performed to provide management strategy and to improve management outcome of elderly patients with intracranial aneurysm. Patients and Methods : We reviewed medical records of 746 consecutive patients with intracranial aneurysm who were admitted from July 1991 to December 1996. They were divided into two age groups : elderly(120 patients aged 65 years or older) and non-elderly(626 patients aged 64 years or younger). We investigated the differences between the two groups in clinical characteristics, management outcome and surgical results. Results : Female(80.0%), internal carotid artery aneurysm(48.9%), poor clinical grade(Hunt and Hess Grade IV, V : 39.8%), postoperative subdural fluid collection(38.2%), and postoperative hydrocephalus(39.7%) were more frequent in the elderly patients. There were no significant differences in the incidence of hypertension, multiple aneurysm, unruptured aneurysm, rebleeding, delayed ischemic neurological deficits, postoperative hemorrhage, and low density on the postoperative brain CT scan. In some cases, surgical clipping of ruptured aneurysm could not be performed due to moribund state or refusal of surgery by the elderly patient's family. Both management outcome and surgical results in elderly aneurysm patients at 3 months after rupture were worse than those of the non-elderly group. The most common reason of unfavorable outcome was poor clinical grade in both groups, while serious medical illness causing unfavorable outcome was more common in the elderly group. Conclusion : Surgical treatment of a ruptured aneurysm should not be avoided in elderly patient solely on the basis of advanced age. If the patients are in good clinical grade, early aneurysm surgery followed by early ambulation should be recommended. Further improvements in outcome may be achieved by thorough knowledge of poor resilience of brain, CSF flow dynamics, and diminished cardiopulmonary reserve in elderly patients with intracranial aneurysm.

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Effect of Gamma Irradiation on Wood Chip Saccharification Pretreated with NaOH (NaOH를 이용한 우드칩의 당화 전처리에 대한 감마선 조사 영향 연구)

  • Kim, Su-mi;Choi, Jong-il;Joe, Min-Ho;Kim, Jong-deog
    • Korean Chemical Engineering Research
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    • v.54 no.3
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    • pp.431-435
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    • 2016
  • The aim of this study was to investigate the effect of gamma irradiation on the pretreatment of wood chips with NaOH solution. The degree of saccharification was quantified by measuring reducing sugar and glucose concentrations after enzymatic hydrolysis. After pretreatment with 10 g/L NaOH, the wood chips were irradiated at the doses of 0, 50, 100, and 200 kGy, respectively. Among the irradiated samples, wood chips irradiated at the dose of 200 kGy had the highest reducing sugar concentration of 12.2 g/L. Also, to define the effect of irradiation before pretreatment, the wood chips were first gamma-irradiated and then pretreated with NaOH. When the NaOH treatment was conducted after irradiation at 200 kGy, the reducing sugar content was further increased to 13.4 g/L and glucose content of the wood chip was as high as 7.9 g/L. These results suggest that gamma irradiation may be the promising method for pretreatment of cellulose biomass.

Dyeing effects of natural pigment from marine bacterium, Microbulbifer sp. PPB12 (해양세균 Microbulbifer sp. PPB12 생성 천연색소의 섬유 염색 효과)

  • Lee, Ga-Eun;Park, Jin-Sook
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.3
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    • pp.527-533
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    • 2017
  • As the clothing industry has advanced, dyeing technologies using various dyes have been developed. In recent years, interest in natural pigments has been increasing because of the negative impact of synthetic pigment on human health; therefore, development and application of microbial pigments is demanded. In this study, the dyeing effects on multifiber fabrics and biological activity were assessed using violet natural pigment from the marine bacterium, Microbulbifer sp. PPB12. The violet pigment produced by cultivation of Microbulbifer sp. PPB12 using Marine broth 2216 for 3 days was extracted using ethanol. Once dissolved in 20% ethanol, the violet pigment could be used to dye bleached cotton, diacetate, and especially polyamide. The optimal temperature, time, pH, and bath ratio under the dyeing conditions were $80^{\circ}C-90^{\circ}C$, more than 1 hour, pH 4-6, and 1:25, respectively. The mordant treatment was more suitable for color expression when $Na_2SO_4$ was used after 10 minutes of dyeing, but no significant difference was observed from untreated samples. The violet pigment also showed antibacterial activity against B. subtilis. The results of the present study indicate that the marine bacterial pigment could be an alternative for textile dyeing as a natural dye with antibacterial activity.