• Journal of Technology Innovation
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• v.21 no.2
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• pp.169-197
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• 2013

Despite many theoretical and empirical studies, general causality between IPRs system, firm technological innovation and financial performance is not clear. This study notices that the core factor to create financial performance is different by each industry. The study analyzed the effect of IPRs system on innovation and economic growth targeting 3 industries; pharmaceutical industry to which the basic track of creating performance is applied (strengthening IPRs${\rightarrow}$increasing R&D input/output${\rightarrow}$increasing sales); semiconductor industry where the relationship between stronger IPRs and R&D input/output is weak; and shipbuilding industry which has weak correlation between R&D and sales. It used panel data for 15 years since TRIPs when the patent institution in Korea reached up to the level of advanced countries, and applied the dynamic regression model which estimates the fixed effect model with difference-GMM. As a result, stronger IPRs increased R&D input/output, and financial performance in pharmaceutical industry, but has no influence on semiconductor and shipbuilding industries. That is, it is necessary to customize the construction of system and policy for strengthening IPRs by each industry, and unitary strengthening or weakening may have no significant impact on financial performance improvement in specific sectors.

• Korean Journal of Medicinal Crop Science
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• v.10 no.2
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• pp.120-125
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• 2002

This study was carried out to find the possibility of use of Solid Phase Microextraction (SPME) for extracting the volatile aroma compounds in the five aromatic plants (Agastache rugosa O. Kuntze, Mentha arvensis Linne, Thymus quinquecostatus Celakovsky, Elsholtzia splendens Nakai, Schizonepta tenuifolia Briquet) belongs to the Labiatae. In the result of the analysis, the volatile aroma compounds were mainly composed monoterpene alcohol (linanol, menthol, ${\alpha}-terpineol$, borneol), monoterpene ketone (limonene, menthone) and sesquiterpene (trans-caryophyllene,${\delta}-cadinene)$. The volatile aroma compounds of Agastache rugosa O. Kuntze and Mentha arvensis Linne were extracted by SPME more identified than the SDE. However, Schizonepta tenuifolia Briquet more identified by the SDE and in Elsholtzia splendens Nakai similar to the SDE. Especially, the SPME showed the sesquiterpene contents was more than the SDE. The major volatile aroma compounds were difference but the composition of those between the SPME and the SDE showed no difference. Within the results, the SPME showed the most convenient and a rapid extraction method to analysis of the volatile aroma compounds.

• Proceedings of the Materials Research Society of Korea Conference
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• 2012.05a
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• pp.72-72
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• 2012

Lithium rechargeable batteries have been widely used as key power sources for portable devices for the last couple of decades. Their high energy density and power have allowed the proliferation of ever more complex portable devices such as cellular phones, laptops and PDA's. For larger scale applications, such as batteries in plug-in hybrid electric vehicles (PHEV) or power tools, higher standards of the battery, especially in term of the rate (power) capability and energy density, are required. In PHEV, the materials in the rechargeable battery must be able to charge and discharge (power capability) with sufficient speed to take advantage of regenerative braking and give the desirable power to accelerate the car. The driving mileage of the electric car is simply a function of the energy density of the batteries. Since the successful launch of recent Ni-MH (Nickel Metal Hydride)-based HEVs (Hybrid Electric Vehicles) in the market, there has been intense demand for the high power-capable Li battery with higher energy density and reduced cost to make HEV vehicles more efficient and reduce emissions. However, current Li rechargeable battery technology has to improve significantly to meet the requirements for HEV applications not to mention PHEV. In an effort to design and develop an advanced electrode material with high power and energy for Li rechargeable batteries, we approached to this in two different length scales - Atomic and Nano engineering of materials. In the atomic design of electrode materials, we have combined theoretical investigation using ab initio calculations with experimental realization. Based on fundamental understanding on Li diffusion, polaronic conduction, operating potential, electronic structure and atomic bonding nature of electrode materials by theoretical calculations, we could identify and define the problems of existing electrode materials, suggest possible strategy and experimentally improve the electrochemical property. This approach often leads to a design of completely new compounds with new crystal structures. In this seminar, I will talk about two examples of electrode material study under this approach; $LiNi_{0.5}Mn_{0.5}O_2$ based layered materials and olivine based multi-component systems. In the other scale of approach; nano engineering; the morphology of electrode materials are controlled in nano scales to explore new electrochemical properties arising from the limited length scales and nano scale electrode architecture. Power, energy and cycle stability are demonstrated to be sensitively affected by electrode architecture in nano scales. This part of story will be only given summarized in the talk.

• Journal of Applied Biological Chemistry
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• v.58 no.3
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• pp.219-226
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• 2015

The anticancer activity of a methanolic extract from lemon leaves (MLL) was assessed in MCF-7-SC human breast cancer stem cells. MLL induced apoptosis in MCF-7-SC, as evidenced by increased apoptotic body formation, sub-G1 cell population, annexin V-positive cells, Bax/Bcl-2 ratio, as well as proteolytic activation of caspase-9 and caspase-3, and degradation of poly (ADP-ribose) polymerase (PARP) protein. Concomitantly, MLL induced the formation of acidic vesicular organelles, increased LC3-II accumulation, and reduced the activation of Akt, mTOR, and p70S6K, suggesting that MLL initiates an autophagic progression in MCF-7-SC via the Akt/mTOR pathway. Epithelial-mesenchymal transition (EMT), a critical step in the acquisition of the metastatic state, is an attractive target for therapeutic interventions directed against tumor metastasis. At low concentrations, MLL induced anti-metastatic effects on MCF-7-SC by inhibiting the EMT process. Exposure to MLL also led to an increase in the epithelial marker E-cadherin, but decreased protein levels of the mesenchymal markers Snail and Slug. Collectively, this study provides evidence that lemon leaves possess cytotoxicity and anti-metastatic properties. Therefore, MLL may prove to be beneficial as a medicinal plant for alternative novel anticancer drugs and nutraceutical products.

• Journal of Powder Materials
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• v.24 no.2
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• pp.133-140
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• 2017

This study investigates the oxidation properties of Fe-14Cr ferritic oxide-dispersion-strengthened (ODS) steel at various high temperatures (900, 1000, and $1100^{\circ}C$ for 24 h). The initial microstructure shows that no clear structural change occurs even under high-temperature heat treatment, and the average measured grain size is 0.4 and $1.1{\mu}m$ for the as-fabricated and heat-treated specimens, respectively. Y-Ti-O nanoclusters 10-50 nm in size are observed. High-temperature oxidation results show that the weight increases by 0.27 and $0.29mg/cm^2$ for the as-fabricated and heat-treated ($900^{\circ}C$) specimens, and by 0.47 and $0.50mg/cm^2$ for the as-fabricated and heat-treated ($1000^{\circ}C$) specimens, respectively. Further, after 24 h oxidation tests, the weight increases by 56.50 and $100.60mg/cm^2$ for the as-fabricated and heat-treated ($1100^{\circ}C$) specimens, respectively; the latter increase is approximately 100 times higher than that at $1000^{\circ}C$. Observation of the surface after the oxidation test shows that $Cr_2O_3$ is the main oxide on a specimen tested at $1000^{\circ}C$, whereas $Fe_2O_3$ and $Fe_3O_4$ phases also form on a specimen tested at $1100^{\circ}C$, where the weight increases rapidly. The high-temperature oxidation behavior of Fe-14Cr ODS steel is confirmed to be dominated by changes in the $Cr_2O_3$ layer and generation of Fe-based oxides through evaporation.

• Applied Biological Chemistry
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• v.49 no.2
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• pp.135-139
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• 2006

This study was carried out to investigate the cosmeceutical activities of Persicae semen. Cosmeceutical activities include anti-oxidant, tyrosinase inhibition effects and nitrite scavenging ability. The Persicae semen was divided into three parts, Bean of Persicae semen (BPS), Shell of Persicae semen (SPS) and Nibs of Persicae semen (NPS). In the electron donating ability test, 1,000ppm of water extract from BPS showed an effect of 89%, while 1,000 ppm of ethanol extract from SPS showed an effect of 87%. These results are higher compared to those of BHA at the equal concentration. We were able to get an effect of 98% from all of Persicae semen ethanol extract of 10,000 ppm in the tyrosinase inhibition test. Nitrite scavenging ability test, ethanol extract from BPS was decreasing to 96% by addition of 1,000ppm. According to these results, we find that Persicae semen applicable to advanced material for cosmetics. From the above results, it was confirmed that Persicae semen could be used in functional cosmetics.

• Archives of design research
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• v.14 no.3
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• pp.7-14
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• 2001

Modern graphic design is creating a new area of graphic design due to the development of computer technology as it changes the existing world of graphic design with a variety of advanced style of image. It is true, however, that the basic principles and images in the modern design are influenced by the visual principles and methods elaborated and changed by the numerous creative works that is well representing the visual features of graphic design trends from the early 20th century to the mid century. The style of graphic design at the time which is generally referred to as 'modern graphic design' went through Pictorial modernism, Constructivism, De Stijl, Bauhaus after the beginning of 20C design, Art Noueau. It spread over the world in the ear of Swiss graphic design and New York graphic design that create the basic principles and styles in modern graphic design. This study examines visual features and flow of graphic design from the early years in the 20th century to the middle of the century, the foundation ear of principles in the modern graphic design. It will give a systematic and fundamental understanding of graphic design and visual features of it while it will be in a research process to create a new graphic style.

• Archives of design research
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• v.15 no.1
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• pp.247-256
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• 2002

'gender' means sex in a social sense and 'sex'is more close to the concept of that discussed in biological light. 'Gender is more adequate word in expressing gender equality of both sexes than 'sex'that gives us discriminating impression and implies tout we should actualize equality between both sexes in all field of social activities. Though more and more women have been advanced into the job that was once regarded as a men only-area and the concrete list of iou for men and women has been changed in the process of job structure transition, women stiff take full charge of all kind of houseworks so they're still under the double torture of housework and their job. Most of the job in which men used to engaged in the past is now mechanized. and we can't deny that modern technology triggered women's participation in public affairs by helping them to lead comfortable family life without any assistant or trustee for housework. Under these trend of our times, we made an attempt to look into design mainly from the standpoint of women by raising the issue of correlation between women's labor in society and houseworks in the hope that current design and changes into one that can rejects women's position and allows them independent choice in the field involved with our real life.

• Journal of Science Education
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• v.36 no.1
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• pp.130-138
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• 2012

The purpose of this study was to investigate perceptions of high school students and science teachers about high school fusing science. Science teachers and high school students perceived that high school fusing science was related to various areas and they preferred to be taught separately from each area. Science teachers perceived that high school fusing science improved the understanding in the area of scientific common knowledge, advanced technology, and the history of science, but neither scientific writing nor discussion were actively involved. It also didn't contribute to the enhancement of scientific thinking and communication skill. Especially, high school students believed that they were more interested in science through fusing science. On the other hand, teachers believed that this high school fusing science might not impact student's learning and generate negative perception. Science teachers and students perceived that they were more interested in fusing science because it was combination of many areas in science. They also perceived that contents in fusing science were more related to their daily life.

• Science of Emotion and Sensibility
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• v.19 no.4
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• pp.41-54
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• 2016

Recently, in the arena of online shopping, the gap between offline channel and online channel tends to be narrowed significantly. Though previous studies also represent this trend, it still remains ambiguous how much offline trust has a significant influence on user's online shopping behaviors. Furthermore, those research issues such as how individual neuroticism, uncertainty, and transaction cost plays an important role in explaining user's online shopping satisfaction and continuance intention. In this sense, this study aims to organize a new research model including offline trust, uncertainty, transaction cost, satisfaction, and continuance intention. Especially, we are interested in investigating how much moderating effects the individual neuroticism possesses for the paths among the rest of constructs. By using 406 valid questionnaires, we found empirically that transaction cost affects user's online shopping continuance intention, but it has no influence on satisfaction. The individual neuroticism has full moderating effects on the paths on the rest of constructs included in the proposed research model.