• Title/Summary/Keyword: Advanced Model

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Recent Trend in Measurement Techniques of Emotion Science (감성과학을 위한 측정기법의 최근 연구 동향)

  • Jung, Hyo-Il;Park, Tae-Sun;Lee, Bae-Hwan;Yun, Sung-Hyun;Lee, Woo-Young;Kim, Wang-Bae
    • Science of Emotion and Sensibility
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    • v.13 no.1
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    • pp.235-242
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    • 2010
  • Emotion science is one of the rapidly expanding engineering/scientific disciplines which has a major impact on human society. Such growing interests in emotion science and engineering owe the recent trend that various academic fields are being merged. In this paper we review the recent techniques in the measuring the emotion related elements and applications which include animal model system to investigate the neural network and behaviour, artificial nose/neuronal chip for in-depth understanding of sensing the outer stimuli, metabolic controlling using emotional stimulant such as sounds. In particular, microfabrication techniques made it possible to construct nano/micron scale sensing parts/chips to accommodate the olfactory cells and neuron cells and gave us a new opportunities to investigate the emotion precisely. Recent developments in the measurement techniques will be able to help combine the social sciences and natural sciences, and consequently expand the scope of studies.

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Recent Advancement on the Knowledges of Meiotic Division (I) (減數分裂, 最近의 進步(I))

  • 한창열
    • Korean Journal of Plant Tissue Culture
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    • v.25 no.6
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    • pp.453-475
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    • 1998
  • During the 100 years since the initial discovery of meiotic phenomenon many brilliant aspects have been elucidated, but further researches based on light microscopy alone as an experimental tool have been found to have some limits and shortcomings. By the use of electron microscopy and armed with the advanced knowledges on modern genetics and biochemistry it has been possible to applu molecular technology in gaining information on the detailed aspects of meiosis. As synapsis takes place, a three-layered proteinous structure called the synatonemal complex starts to form in the space between the homologous chromosomes. To be more precise, it begins to form along the paired chromosomes early in the prophase I of meiotic division. The mechanism that leads to precise point-by-point pairing between homologous chromocomes division. The mechamism that leads to precise point-by-point pairing between homologous chromosomes remains to be ascertained. Several items of information, however, suggest that chromsome alignment leading to synapsis may be mediated somehow by the nuclear membrane. Pachytene bivalents in eukaryotes are firmly attached to the inner niclear membrane at both termini. This attached begins with unpaired leptotene chromosomes that already have developed a lateral element. Once attached, the loptotene chromosomes begin to synapse. A number of different models have been proposed to account for genetic recombination via exchange between DNA strands following their breakage and subsequent reunion in new arrangement. One of the models accounting for molecular recombination leading to chromatid exchange and chiasma formation was first proposed in 1964 by Holliday, and 30 years later still a modified version of his model is favored. Nicks are made by endomuclease at corresponding sites on one strant of each DNA duplex in nonsister chromatid of a bivalent during prophase 1 of meiosis. The nicked strands loop-out and two strands reassociate into an exchanged arrangement, which is sealed by ligase. The remaining intact strand of each duplex is nicked at a site opposite the cross-over, and the exposed ends are digested by exonuclease action. Considerable progress has been made in recent years in the effort to define the molecular and organization features of the centromere region in the yeast chromosome. Centromere core region of the DNA duplex is flanked by 15 densely packed nucleosomes on ons side and by 3 packed nucleosomes on the other side, that is, 2000 bp on one side and 400 400 bp in the other side. All the telomeres of a given species share a common DNA sequence. Two ends of each chromosome are virtually identical. At the end of each chromosome there exist two kinds of DNA sequence" simple telpmeric sequences and telpmere-associated sequencies. Various studies of telomere replication, function, and behabior are now in progress, all greatly aided by molecular methods. During nuclear division in mitosis as well as in meiosis, the nucleili disappear by the time of metaphase and reappear during nuclear reorganizations in telophase. When telophase begins, small nucleoli form at the NOR of each nucleolar-organizing chromosome, enlarge, and fuse to form one or more large nucleoli. Nucleolus is a special structure attached top a specific nucleolar-organizing region located at a specific site of a particular chromosome. The nucleolus is a vertical factory for the synthesis of rRNAs and the assenbly of ribosome subunit precursors.sors.

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Analysis of Frequency Response Curve for Conduction-Cooled Power Capacitors (전도 냉각 파워 커패시터의 주파수 응답 곡선 분석)

  • An, Gyeong Moon;Kim, Hiesik
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.10
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    • pp.123-130
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    • 2016
  • High-frequency induction heating equipment can heat the metal by applying a High-Frequency power to the resonant circuit. The resonance circuit is composed of the work coil and the conduction-cooled power capacitor, it influences the performance of the heat treatment equipment according to the characteristics of the capacitor. However, dependence on conduction-cooled power capacitor's import is high due to lack of core technology research and development. Minimizing the generation of internal heat transmitted inside during LC resonance, reduce the reactive power loss, there is a need for a capacitor within the voltage characteristic outstanding. To implement localization it is vital that prior study of the analysis on the frequency response characteristic for the finished capacitor advanced manufacturer be implemented. Studying the interpolation method to read the value at any point of the characteristic curve for a given log-log scale was applied to the analysis tool of the capacitor by my proposed algorithm. The simulation for reproducing frequency response curves was attempted by assuming a capacitor in a simplified series equivalent RC circuit to obtain the equivalent series resistance value. It was confirmed that the reproduction rate was the result value above 83% as compared to the simulation of the properties and characteristics on the actual reactive power for Peak value, and that the algorithm can be applicable when analyzing and predicting the characteristic curves of a simpled model capacitor.

Periodontal and endodontic pathology delays extraction socket healing in a canine model

  • Kim, Jung-Hoon;Koo, Ki-Tae;Capetillo, Joseph;Kim, Jung-Ju;Yoo, Jung-Min;Ben Amara, Heithem;Park, Jung-Chul;Schwarz, Frank;Wikesjo, Ulf M.E.
    • Journal of Periodontal and Implant Science
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    • v.47 no.3
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    • pp.143-153
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    • 2017
  • Purpose: The aim of the present exploratory study was to evaluate extraction socket healing at sites with a history of periodontal and endodontic pathology. Methods: The mandibular 4th premolar teeth in 5 adult beagle dogs served as experimental units. Periodontal and endodontic lesions were induced in 1 premolar site in each animal using wire ligatures and pulpal exposure over 3 months (diseased sites). The contralateral premolar sites served as healthy controls. The mandibular 4th premolar teeth were then extracted with minimal trauma, followed by careful wound debridement. The animals were sacrificed at days 1, 7, 30, 60, and 90 post-extraction for analysis, and the healing patterns at the healthy and diseased extraction sites were compared using radiography, scanning electron microscopy, histology, and histometry. Results: During the first 7 days of healing, a significant presence of inflammatory granulation tissue was noted at the diseased sites (day 1), along with a slightly accelerated rate of fibrin clot resolution on day 7. On day 30, the diseased extraction sites showed a greater percentage of persistent fibrous connective tissue, and an absence of bone marrow formation. In contrast, healthy sites showed initial signs of bone marrow formation on day 30, and subsequently a significantly greater proportion of mature bone marrow formation on both days 60 and 90. Radiographs exhibited sclerotic changes adjoining apical endodontic lesions, with scanning electron microscopy showing collapsed Volkmann canals protruding from these regions in the diseased sites. Furthermore, periodontal ligament fibers exhibited a parallel orientation to the alveolar walls of the diseased sites, in contrast to a perpendicular arrangement in the healthy sites. Conclusions: Within the limitations of this study, it appears that a history of periodontal and endodontic pathology may critically affect bone formation and maturation, leading to delayed and compromised extraction socket healing.

The Comparison of Survival Rates of Postoperative Adjuvant Chemotherapies in The Stage III Gastric Cancer Patients (3기 위암환자에서 시행한 술 후 보조항암화학요법들의 생존율 비교)

  • Kim, Eun-Mi;Kim, Se-Won;Kim, Sang-Woon;Song, Sun-Kyo
    • Journal of Yeungnam Medical Science
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    • v.23 no.2
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    • pp.193-204
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    • 2006
  • Purpose: Various postoperative adjuvant chemotherapy regimens have been proposed for the patients with advanced gastric cancer. The majority of clinical trials have shown no significant difference in the survival benefit. The aim of this study was to compare the survival rates of postoperative adjuvant chemotherapies used in stage III gastric cancer patients who received curative gastrectomy. Materials and Methods: Between 1990 and 1999, a survival analysis was performed in 260 patients who received curative gastric resection and postoperative adjuvant chemotherapy. The patients were divided into four groups according to the chemotherapeutic regimens received. The groups were: the F group: furtulon alone, FM group: furtulon and mitomycin, FAM group: 5-FU, adriamycin and mitomycin, FLEP group: 5-FU, leucovorin, etoposide and cisplatin. The survival rates were analyzed using the Kaplan-Meier method and the Cox proportional hazards model. Results: There were no differences among the groups of patients with regard to tumor characteristics except for lymph node metastasis and the ratio of metastasis to lymph nodes. In the FLEP group, the ratio of metastasis to lymph nodes was higher than in the other groups. The five and ten year survival rates of F, FM, FAM and FLEP were 51.9%, 28.9%, 59.5%, 49.8%, 66.1%, 57.4% and 30.0%, 27.5%, respectively. The univariate analysis showed that age, Borrmann type, lymph node metastasis, ratio of metastasis to lymph nodes, postoperative adjuvant chemotherapy and recurrence were significant factors for survival. For the multivariate analysis, recurrence, age, Borrmann type, ratio of lymph node metastasis and lymph node dissection were independent prognostic factors; however, the postoperative adjuvant chemotherapy was not an independent prognostic factor. Conclusion: The FAM regimen was the most beneficial postoperative adjuvant chemotherapy for improved survival rates; the FM regimen was the second and the FLEP regimen was the last. In order to determine the effectiveness of postoperative adjuvant chemotherapy in stage III gastric cancer, well designed prospective studies including a surgery only group will be needed.

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A numerical study on the fatigue evaluation of mark-III LNG primary barrier (수치해석을 이용한 Mark-III LNG 1차 방벽에 대한 피로 평가)

  • Kwon, Sun-Beom;Kim, Myung-Sung;Lee, Jae-Myung
    • Journal of Advanced Marine Engineering and Technology
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    • v.41 no.4
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    • pp.337-344
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    • 2017
  • The demand of liquified natural gas is increasing due to environmental issues. This reason has resulted in increasing the capacity of liquified natural gas cargo tank. The Mark-III type primary barrier directly contacts liquified natural gas. Also, the primary barrier is under various loading conditions such as weight of liquified natural gas and sloshing loads. During a ship operation, various loads can cause fatigue failure. Therefore, the fatigue life prediction should be evaluated to prevent leakage of liquified natural gas. In the present study, the fatigue analysis of insulation system including primary barrier is performed using a finite element model. The fatigue life of primary barrier is carried out using a numerical study. The value of principle stress and the location of maximum principle stress range are calculated, and the fatigue life is evaluated. In addition, the effects on the insulation panel status and the arrangement of knot or corrugation are analyzed by comparing the fatigue life of various models. The insulation system which has best structural performance of primary barrier was selected to ensure structural integrity in fatigue assessment. These results can be used as a design guideline and a fundamental study for the fatigue assessment of primary barrier.

A Study on the Development of Creative and Cooperative Learning Spaces for University Libraries in Korea (국내 대학도서관 창의·협력 학습공간 조성에 관한 연구)

  • Jung, Youngmi;Lee, Eun-Ju
    • Journal of Korean Library and Information Science Society
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    • v.51 no.1
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    • pp.201-225
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    • 2020
  • In order to respond to changes in college's educational goals and talents, university libraries need to be transformed into spaces that support creative and collaborative learning. Apart from overseas cases, it is necessary to discuss the development of creative and collaborative learning spaces appropriate to the situation of Korean university libraries. This purpose of this study is to provide an effective guide to university libraries planning to develop creative and cooperative learning spaces. To this end, this study conducted a literature review to define the concept of a creative and collaborative learning space in a university library, collected and analyzed cases of creative and collaborative learning space of Korean university libraries, and proposed a model for developing creative and collaborative learning space for university library. Case collection was carried out through field visits to 12 university libraries. In addition, in-depth interviews were conducted with the staffs in charge of the construction and operation of five university libraries selected in consideration of the operating entity, region, and scale. This study is meaningful in that it intensively researched and analyzed the advanced cases of creative and collaborative learning spaces in Korea to derive suggestions that can be used in the field of domestic university libraries.

Ramp Activity Expert System for Scheduling and Co-ordination (공항의 계류장 관리 스케줄링 및 조정을 위한 전문가시스템)

  • Jo, Geun-Sik;Yang, Jong-Yoon
    • Journal of Advanced Navigation Technology
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    • v.2 no.1
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    • pp.61-67
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    • 1998
  • In this paper, we have described the Ramp Activity Coordination Expert System (RACES) which can solve aircraft parking problems. RACES includes a knowledge-based scheduling problem which assigns every daily arriving and departing flight to the gates and remote spots with the domain specific knowledge and heuristics acquired from human experts. RACES processes complex scheduling problem such as dynamic inter-relations among the characteristics of remote spots/gates and aircraft with various other constraints, for example, custome and ground handling factors at an airport. By user-driven modeling for end users and knowledge-driven near optimal scheduling acquired from human experts, RACES can produce parking schedules of aircraft in about 20 seconds for about 400 daily flights, whereas it normally takes about 4 to 5 hours by human experts. Scheduling results in the form of Gantt charts produced by the RACES are also accepted by the domain experts. RACES is also designed to deal with the partial adjustment of the schedule when unexpected events occur. After daily scheduling is completed, the messages for aircraft changes and delay messages are reflected and updated into the schedule according to the knowledge of the domain experts. By analyzing the knowledge model of the domain expert, the reactive scheduling steps are effectively represented as rules and the scenarios of the Graphic User Interfaces (GUI) are designed. Since the modification of the aircraft dispositions such as aircraft changes and cancellations of flights are reflected to the current schedule, the modification should be notified to RACES from the mainframe for the reactive scheduling. The adjustments of the schedule are made semi-automatically by RACES since there are many irregularities in dealing with the partial rescheduling.

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A study on 3-D indoor localization based on visible-light communication considering the inclination and azimuth of the receiver (수신기의 기울기 및 방위를 고려한 가시광 통신기반 3차원 실내 위치인식에 대한 연구)

  • Kim, Won-Yeol;Zin, Hyeon-Cheol;Kim, Jong-Chan;Noh, Duck-Soo;Seo, Dong-Hoan
    • Journal of Advanced Marine Engineering and Technology
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    • v.40 no.7
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    • pp.647-654
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    • 2016
  • Indoor localization based on visible-light communication using the received signal strength intensity (RSSI) has been widely studied because of its high accuracy compared with other wireless localization methods. However, because the RSSI can vary according to the inclination and azimuth of the receiver, a large error can occur, even at the same position. In this paper, we propose a visible-light communication-based 3-D indoor positioning algorithm using the Gauss-Newton technique in order to reduce the errors caused by the change in the inclination of the receiver. The proposed system reduces the amount of computations by selecting the initial position of the receiver through the linear least-squares method (LSM), which is applied to the RSSIs, and improves the position accuracy by applying the Gauss-Newton technique to the 3-D nonlinear model that contains the RSSIs acquired by the changes in the azimuth and inclination of the receiver. In order to verify the validity of the proposed algorithm in an indoor space with dimensions of $6{\times}6{\times}3m$ where 16 LED lights are installed, we compare and analyze the errors of the conventional linear LSM-based trilateration technique and the proposed algorithm according to the changes in the inclination and azimuth of the receiver. The experimental results show that the location accuracy of the proposed algorithm is improved by 82.5% compared to the conventional LSM-based trilateration technique.

Development of CCTV Cooperation Tracking System for Real-Time Crime Monitoring (실시간 범죄 모니터링을 위한 CCTV 협업 추적시스템 개발 연구)

  • Choi, Woo-Chul;Na, Joon-Yeop
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.12
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    • pp.546-554
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    • 2019
  • Typically, closed-circuit television (CCTV) monitoring is mainly used for post-processes (i.e. to provide evidence after an incident has occurred), but by using a streaming video feed, machine-based learning, and advanced image recognition techniques, current technology can be extended to respond to crimes or reports of missing persons in real time. The multi-CCTV cooperation technique developed in this study is a program model that delivers similarity information about a suspect (or moving object) extracted via CCTV at one location and sent to a monitoring agent to track the selected suspect or object when he, she, or it moves out of range to another CCTV camera. To improve the operating efficiency of local government CCTV control centers, we describe here the partial automation of a CCTV control system that currently relies upon monitoring by human agents. We envisage an integrated crime prevention service, which incorporates the cooperative CCTV network suggested in this study and that can easily be experienced by citizens in ways such as determining a precise individual location in real time and providing a crime prevention service linked to smartphones and/or crime prevention/safety information.