• Title/Summary/Keyword: Adult diseases

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Ectopic Schistosomiasis Involving Axillary Lymph Nodes

  • Xia Chen;Nian'an He
    • Parasites, Hosts and Diseases
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    • v.60 no.6
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    • pp.409-411
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    • 2022
  • Axillary lymph node schistosomiasis is a form of ectopic schistosomiasis, in which the Schistosoma adult worms or eggs are infected in the axillary lymph nodes. A 53-year-old woman visited our hospital with a small mass in the right armpit, which had been present for over 1 month. Histological examination of biopsy samples from the right axillary lymph nodes revealed granulomas containing calcified Schistosoma eggs. This is the first authentic case of ectopic schistosomiasis identified in the axillary lymph nodes.

Morphological Studies of Developmental Stages of Oculotrema hippopotami (Monogenea: Polystomatidae) Infecting the Eye of Hippopotamus amphibius (Mammalia: Hippopotamidae) Using SEM and EDXA with Notes on Histopathology

  • Rubtsova, Nataliya Yu.;Heckmann, Richard A.;Smit, Willem J.;Luus-Powell, Wilmien J.;Halajian, Ali;Roux, Francois
    • Parasites, Hosts and Diseases
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    • v.56 no.5
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    • pp.463-475
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    • 2018
  • The present study was performed to observe histopathological effects of Oculotrema hippopotami Stunkard, 1924 infection in the eye of Hippopotamus amphibius, as well as to reveal new details of morphology and structural features of this monogenean and its comparison between 2 age stages of the parasite. This was done using both light and scanning electron microscopy, energy dispersive X-ray analysis (EDXA) and histopathology. The presence of a mixture of different generations (adult and sub-adult) in one host individual is common for Oculotrema Stunkard, 1924 in contrast to Polystoma Zeder, 1800. New metrical and graphical information obtained for adults and sub-adults compared with the previous studies. Here we show the presence of genital papillae in adults, metrical data on the distal part of the vas deferens. SEM micrographs of sperm ejaculatory structures and information about the flattened dorsal side of the body provided for the first time. Histopathological changes, such as necrosis and hemorrhage in host tissues as a result of O. hippopotami attachment structures are described. Structural analysis of different body parts of O. hippopotami of both age groups are also included. We show qualitative differences in the presence of hardening ions (S, P, Ca) in attachment structures (oral and haptor suckers) that increase with the age of the worm. The presence of sub-adults and adults on the same host, together with high levels of infection without high pathogenicity may account for Oculotrema being one of the most successful parasites among the Monogenea.

Neonatal Patent Ductus Arteriosus Ligation Operations Performed by Adult Cardiac Surgeons

  • Chung, Yoon Sang;Cho, Dai Yun;Kang, Hyun;Lee, Na Mi;Hong, Joonhwa
    • Journal of Chest Surgery
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    • v.50 no.4
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    • pp.242-246
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    • 2017
  • Background: Patent ductus arteriosus (PDA) ligation is usually performed by congenital cardiac surgeons. However, due to the uneven distribution of congenital cardiac surgeons in South Korea, many institutions depend solely on adult cardiac surgeons for congenital cardiac diseases. We report the outcomes of PDA ligations performed by adult cardiac surgeons at our institution. Methods: The electronic medical records of 852 neonates at Chung-Ang University Hospital, Seoul, South Korea from November 2010 to May 2014 were reviewed to identify patients with PDA. Results: Of the 111 neonates with a diagnosis of PDA, 26 (23%) underwent PDA ligation. PDAs were ligated within 28 days of birth (mean, $14.5{\pm}7.8days$), and the mean gestational age of these patients was $30.3{\pm}4.6weeks$ (range, 26 to 40 weeks) with a mean birth weight of $1,292.5{\pm}703.5g$ (range, 480 to 3,020 g). No residual shunts through the PDA were found on postoperative echocardiography. There was 1 case of 30-day mortality (3.8%) due to pneumonia, and 6 cases of in-hospital mortality (23.1%) after 30 days, which is comparable to results from other centers with congenital cardiac surgery programs. Conclusion: Although our outcomes may not be generalizable to all hospital settings without a congenital cardiac surgery program, in select centers, PDA ligations can be performed safely by adult cardiac surgeons if no congenital cardiac surgery program is available.

The Factors Influencing the Bone Mineral Density in Korean Adult Men : Based on Korea National Health and Nutrition Examination Survey 2010~2011 Data (우리나라 성인 남성의 골밀도에 연관성을 보이는 요인 : 국민건강영양조사자료, 2010~2011)

  • Lee, Hye-Sang
    • Korean Journal of Community Nutrition
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    • v.22 no.2
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    • pp.136-144
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    • 2017
  • Objectives: The purpose of this study was to determine which factors influence the bone mineral density (BMD) of total femur (TF), femoral neck (FN) and lumbar spine (LS) of the adult men by analyzing nationally representative Korean survey data. Methods: This study was conducted based on the data of 1,770 men aged 19-64 years from the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V), 2010~2011. The BMD was analyzed by various factors (general characteristics, anthropometric data, health habits, chronic diseases, nutrient intake status). SPSS statistics for complex samples was used to analyze the data. Results: We observed that the BMD decreased significantly with aging. The BMD in each of the second lowest quartile of waist circumference (in TF & FN) and body mass index (in TF & LS) was lower than the respective BMD in the highest quartile group. The BMD in FN was higher in the group who reported the weight training. The BMD in LS was lower in hypercholesterolemia group than in the normal group. The BMD in TF, FN and LS was lower in hypertriglyceridemia group and in diabetes group than in the normal group. The BMD in TF, FN and LS was higher in the group with < Estimated Average Requirement iron intake. But there was no evidence to suggest that the BMD was related with educational level, income level, smoking, alcohol intake, anemia and nutrient intake status (except for iron). Conclusions: This study suggested that aging, waist circumference, body mass index, weight training, hypercholesterolemia, hypertriglycemia, diabetes were site-specifically associated with the BMD in TF, FN and LS in the adult men. These bone site-specific factors need to be considered for the prevention of osteoporosis.

Developmental inhibition of Drosophila suzukii by ionizing radiation

  • KIM, Junheon;KIM, Jeongmin;LEE, Yeon Jeong;PARK, Chung Gyoo
    • Entomological Research
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    • v.48 no.5
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    • pp.331-338
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    • 2018
  • Spotted wing drosophila (SWD) has emerged as a major invasive insect pest of small berry fruits in the Americas and Europe since the late 2000s. Thus, phytosanitary treatment of commodities for export is imperative to prevent the movement of viable SWD to newer areas. In the present study, all developmental stages of SWD were irradiated with different doses of gamma and electron beam radiation to assess developmental inhibition to identify potential quarantine doses of the radiations. Ionizing radiation induced developmental inhibition of all stages of SWD. The effective doses for 99% inhibition ($ED_{99}$) of hatching, pupariation, and adult emergence from irradiated eggs for gamma radiation were 882, 395 and 39 Gy, respectively, compared with 2849, 687, and 41 Gy, respectively, for electron beam radiation. The $ED_{99}$ for inhibition of pupariation and adult emergence in irradiated larvae were 703 and 47 Gy, respectively, for gamma radiation, and 619 and 33 Gy, respectively, for electron beam radiation. Pupal irradiation did not completely inhibit adult emergence, even at 300 Gy. However, irradiation with ${\geq}100Gy$ of puparia induced adult sterility, with no egg production at all. The $ED_{99}$ for inhibition of $F_1$ egg hatchability from adults irradiated with gamma radiation and electron beam radiation was estimated to be 424 and 125 Gy, respectively. The results of the present study suggest that gamma radiation and electron beam radiation are alternatives for phytosanitary treatment. Irradiation with 100 Gy could be suggested as a potential dose for egg, larval, and pupal quarantine treatment of SWD.

Clinical Problems in ML II and III: Extra-skeletal Manifestations

  • Park, Sung Won
    • Journal of mucopolysaccharidosis and rare diseases
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    • v.2 no.1
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    • pp.5-7
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    • 2016
  • Mucolipidoses II and III alpha/beta (ML II and ML III) are lysosomal disorders in which the essential mannose-6-phosphate recognition marker is not synthesized onto lysosomal hydrolases and other glycoproteins. The disorders are caused by mutations in GNPTAB, which encodes two of three subunits of the heterohexameric enzyme, N-acetylglucosamine-1-phosphotransferase ML II, recognizable at birth, often causes intrauterine growth impairment and sometimes the prenatal "Pacman" dysplasia. The main postnatal manifestations of ML II include gradual coarsening of neonatally evident craniofacial features, early cessation of statural growth and neuromotor development, dysostosis multiplex and major morbidity by hardening of soft connective tissue about the joints and in the cardiac valves. Fatal outcome occurs often before or in early childhood. ML III with clinical onset rarely detectable before three years of age, progresses slowly with gradual coarsening of the facial features, growth deficiency, dysostosis multiplex, restriction of movement in all joints before or from adolescence, painful gait impairment by prominent hip disease. Cognitive handicap remains minor or absent even in the adult, often wheelchair-bound patient with variable though significantly reduced life expectancy. As yet, there is no cure for individuals affected by these diseases. So, clinical manifestations and conservative treatment is important. This review aimed to highlight the extra-skeletal clinical problems in ML II and III.

Cryopreservation of Pine Wood Nematode, Bursaphelenchus xylophilus

  • Park, Ju-Yong;Shin, Keum-Chul;Kim, Kyung-Hee;Lee, Seung Kyu;Lee, Jong Kyu
    • Journal of Korean Society of Forest Science
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    • v.94 no.5 s.162
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    • pp.334-337
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    • 2005
  • Pine wood nematode isolates from Haman, Gyoungsangnam-do were cryopreserved with three different cryoprotectants (glycerol, ethylene glycol and dimethylsulfoxide), Nematode Growth medium (NGM) and M 9 buffer solution, respectively, and then survival rate, reproduction ability, and pathogenicity of stored nematodes were compared. Survival rates of juvenile was excellent in 15% glycerol solution as $72{\pm}5.3%$. The survival ability of nematodes at juvenile stage was more efficient than that of nematodes at adult stage. Pre-incubation treatment at $4^{\circ}C$ before storing in liquid nitrogen didn't affect the survival ability of pine wood nematode. When the reproduction ability of nematodes was confirmed on Botrytis cinerea agar plates at $28^{\circ}C$ incubator, there was no difference between cryopreserved and non-cryopreserved. Pathogenic ability of cryopreserved nematodes was also evaluated and confirmed by artificially inoculating them on 2-year old red pine seedlings.

Influential Factors for the Knowledge and Awareness of Adults on Periodontal Diseases and Their Belief (성인의 치주질환에 관한 지식, 인식과 신념에 미치는 영향)

  • Lee, Ji-Yeoun;Lee, Mi-Oak
    • The Journal of the Korea Contents Association
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    • v.16 no.1
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    • pp.295-307
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    • 2016
  • The purpose of this study was to examine the awareness and knowledge of school organizational members about peridontal diseases, their belief in the diseases, attitude and periodontal health in an effort to provide some information on how to ensure successful oral health education and incremental dental care. The subjects in this study were the selected patients who visited school dental clinics. Their ideas of periodontal diseases and periodontal health were analyzed to determine the influential factors. They got a mean of 2.77 in awareness of the epidemiologic characteristics of periodontal diseases, 2.97 in knowledge on the initial symptoms of gingivitis, 2.90 in awareness of the causes of periodontal diseases, 2.95 in awareness of the prevention and treatment of peridontal diseases, and 3.04 in belief in periodontal diseases and attitude. Thus, they had a good understanding and knowledge of periodontal diseases, and they had the right belief and the right attitude as well. They scored relatively lower in several items of periodontal diseases: awareness of tooth loss caused by aging, awareness of the relationship of food to the prevention and occurrence of periodontal diseases, the relationship between toothbrushing time and gingival health, the right toothbrushing method and the right way of dental care.

Assertive Behavior in Asking Smokers Not to Smoke among Patients with Vascular Diseases (혈관질환자의 간접흡연 노출 시 흡연중단에 대한 주장행위 관련 요인)

  • Kim, Eun Kyung;Chae, Young Ran;Jung, Yun Hee;Park, Eun Ha
    • Journal of Korean Biological Nursing Science
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    • v.18 no.1
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    • pp.27-35
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    • 2016
  • Purpose: The purpose of this study was to identify the assertive behavior of asking smokers not to smoke and investigate the factors related to assertive behavior in patients with vascular diseases. Methods: Participants were 203 adult Korean patients with vascular diseases such as cerebral infarction and myocardial infarction. Data were collected using questionnaires that included the characteristics of secondhand smoke (SHS), secondhand smoke-related variables (Health belief model factors, health promotion model factors) and level of assertive behavior. Descriptive statistics, t-test, ANOVA and multiple regression using SPSS/WIN 18.0 were performed. Results: Participants who never ask smokers not to smoke was 39.9%, whereas participants who always ask was 7.4%. There was a weak positive relationship between assertive behavior and susceptibility to disease (r=.18), severity of disease (r=.19), benefit of assertive behavior to SHS exposure (r=.10), barrier of assertive behavior to SHS exposure (r=.24), and self-rated health (r=.21) respectively. There was a moderate positive relationship between assertive behavior and self-efficacy of assertive behavior to SHS exposure (r=.49). Health belief model factors explained 15.7% variance and health promotion model factors explained 27.0% of assertive behavior. Conclusion: The findings of this study suggest that self-efficacy of assertive behavior to SHS exposure is a very important factor. Therefore the development of a program to foster self-efficacy of assertive behavior regarding SHS exposure in patients with vascular diseases is needed.

Association between sugary snacking habits and oral disease in Korean adults (한국 성인의 당 함유 간식섭취 행태와 구강질환의 연관성)

  • Lee, Sue-Hyang;Shin, Bo-Mi;Song, Ga-In;Shin, Sun-Jung;Bae, Soo-Myoung
    • Journal of Korean society of Dental Hygiene
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    • v.20 no.1
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    • pp.29-39
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    • 2020
  • Objectives: This study was to examine the association of sugar-containing snacking habits with dental caries and periodontal diseases. Methods: This study was conducted on 2,807 adults who answered both oral examination and food intake frequency survey in the data of 2015 Korea National Health and Nutrition Examination Survey. The intake frequency of sugary snacks was selected from 17 kind of snacks, which had high sugar content and could affect oral disease. We used the complex sample logistic regression using SPSS 23.0 confirmed the correlation of sugary snack intake frequency and oral diseases. Results: 16.9% of all adults had a sugary snack at least three times a day. 20.7% of dental caries patients and 25.8% of people with periodontal diseases consumed sugary snacks more than three times a day. Especially, periodontal diseases were 1.51 times higher(p=0.008) in three or more consuming snacks group than that who ingested sugary snacks less than six times a week, by correcting the general characteristics and oral health behaviors. Conclusions: Oral health in adults affects oral health in old age, so from a public health perspective, integrated intervention is required to manage the self-cultivation health and to create correct eating habits.