• Korean Journal of Clinical Pharmacy
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• v.26 no.1
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• pp.13-23
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• 2016

Background: South Korea is rapidly being an aging-society and the demand of long-term care insurance services for elderly patients is rising. In addition, because the elderly taking multiple medicines, the adherence is lowered and the adverse events are easily occurred. Therefore, many are interested in introducing the geriatric pharmacy specialist to manage this situation. Purpose: By applying a similar program such as the geriatric pharmacy specialist working in nursing home, we conducted this study to evaluate the potential contribution to both the health insurance services and financial savings for the elderly patients. Methods: We conducted a trial in an elderly nursing home to collaborate between doctor and pharmacist making a checklist for improving medication adherence and establish a consultation system. Also we applied a smart phone application in the pharmaceutical care processes. Results: Thereby completing the drug therapy related checklist apply to nursing facilities in South Korea. And we got a performance that improves medication adherence when used in the clinical practice settings. Conclusion: By introducing a training program of pharmacy care managers and geriatric professionals such as the United States and Japan, we revealed the elderly nursing home residents and vulnerable elderly people living alone were improved the medication adherence and it will contributed to the health and quality of life of the patients.

• Korean Journal of Schizophrenia Research
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• v.23 no.2
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• pp.51-57
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• 2020

Treatment-resistant schizophrenia (TRS) has been defined as the persistence of positive symptoms despite two or more trials of antipsychotic medication of adequate dose and duration. TRS is a serious clinical problem and occurs in approximately 30% of patients with schizophrenia. It is important that patients who do not adequately respond to antipsychotics be reevaluated to exclude or address causes other than non-responsiveness to medication, that is, the possibility of pseudo-resistance. In particular, non-adherence to oral antipsychotic treatment should be monitored to rule out pseudo-resistant cases of TRS. Moreover, patients with TRS who take their medication as required may have subtherapeutic antipsychotic plasma levels, secondary to pharmacokinetic factors. In this paper, we review the concept and exclusion of pseudo-resistance, especially owing to non-adherence or pharmacokinetic factors, and present methods to enhance drug adherence.

• Journal of Korea Entertainment Industry Association
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• v.14 no.2
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• pp.213-224
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• 2020

Purpose: This study is a descriptive and secondary analytical study that uses panel data to identify the factors of medication adherence to improve life care of hypertensive patients. Methods: The subjects of this study were 2,484 patients who were taking medication after hypertension using Korea Medical Panel 2015 data (β-version 1.0). Data analysis was performed using Chi-Square, Scheffe's test, and logistic regression using SPSS/win 22.0. Results: The level of medication adherence in patients with hypertension was 94.2%. The factors of medication adherence were gender and age in Model I of demographic factors, and the presence of disability, smoking, and drinking in Model II. Model III, which added drug use factors, was identified as drinking, drug duration, side effects, drug satisfaction, and payment of drug costs. Conclusion: In order to improve life care for hypertension patients, education and interventions on the importance of take medication and side effects of medications and how to take them will be needed in the early stages of diagnosis.

• The Journal of Korean Academic Society of Nursing Education
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• v.30 no.3
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• pp.263-279
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• 2024

Purpose: This study was conducted to evaluate the effects of nurse-led interventions on quality of life, medication adherence, anxiety, and depression in kidney transplant recipients. Methods: A systematic literature review was conducted following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Two researchers independently selected the final literature, and the quality assessment was performed using Cochrane's Risk of Bias tool. Additionally, a meta-analysis was conducted using the statistical software RevMan 5.4 to estimate effect sizes. Results: Among the reviewed 2,264 papers, 8 final papers, including 6 from the literature search and 2 from manual searches, were included in the analysis. The total number of participants included in the analysis was 477. Nurse-led interventions were found to be effective in improving quality of life (d=1.05) and reducing anxiety (d=-0.98) and depression (d=-1.25). Due to the heterogeneity of the measurement tools, the effect size for medication adherence could not be calculated. Despite this, nurse-led interventions were shown to improve medication adherence. In the cases of anxiety and depression, longer intervention periods showed a more significant reduction trend. Conclusion: The results of this study suggest that nurse-led interventions positively impact quality of life, medication adherence, anxiety, and depression in kidney transplant recipients. Therefore, it is important to recognize the crucial role of nurses and explore ways to provide continuous nursing interventions for kidney transplant recipients.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.2
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• pp.919-931
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• 2018

In this study, we developed textile proximity sensor using conductive textile to develop a Medication adherence management system. The textile proximity sensor utilizes the principle of the capacitor, and the ring type sensor used to reduce the fringe-effect. When take medicines, we made a custom PCB that converts the change of the data measured by the sensor into a digital value so that transmitted the PC. In order to compare the performance of the system, we evaluated the correlation between the data variation according to the quantity of pills in the electronic compact scale and the data in this system. As a result, Pearson's correlation coefficient was 0.956(p<0.01), confirmed a good correlation between the scale and our system. Therefore, we concluded that our system evaluated able to whether or not to take medication.

• Journal of East-West Nursing Research
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• v.22 no.2
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• pp.170-177
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• 2016

Purpose: The purpose of this study was to examine the mediating effect of regimen distress in the relationship between medication adherence and glycemic control in men with type 2 diabetes. Methods: A total of 116 patients with type 2 diabetes was recruited for the cross-sectional survey design. Data were analyzed using descriptive statistics, independent t-test, ANOVA, Pearson's correlation coefficient, and multiple regression using Baron and Kenny steps for mediation. Results: The mean score for medication adherence was 6.32, and the mean glycemic control level (HbA1c) was 7.47%. The mean score was 2.37 for regimen distress. There were significant correlations among medication adherence, regimen distress, and HbA1c. Regimen distress had a partial mediating effect (${\beta}$=.22, p=.005) in the relationship between medication adherence and HbA1c (Sobel test: Z=2.47, p=.013). Conclusion: Regimen distress was found to be associated with glycemic control in men with type 2 diabetes. Based on the findings of this study, nursing intervention programs focusing on decreasing regimen distress are highly recommended to improve level of glycemic control in patients with type 2 diabetes.

• Journal of the Korea Convergence Society
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• v.12 no.12
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• pp.125-137
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• 2021

This study is a descriptive investigation study to identify the Convergence factors of the subjective health status, communication with medical personnel and drug misuse on medication adherence. The subjects of this study were 179 senior citizens who used community elderly welfare centers. Data were collected from January 13, 2020 to January 17, 2020. Data analysis was performed using frequency, percentage, mean, standard deviation, t-test, ANOVA. Post-Hoc Test Was performed using Scheffe test, Pearson's correlation coefficients and multiple regression analysis. The regression equation of this study explained 24% of medication adherence. Drug misuse(𝛽=-4.32, p=<.001) was the factor that had the greatest influence on the medication adherence, followed by the presence or absence of chronic disease (𝛽=-3.04, p=.003), marital status (𝛽=2.64, p=.009), and communication with medical personnel (𝛽=2.26, p=.025 ) in that order. Therefore, it is necessary to establish a convergence system of medication adherence for the elderly using community welfare centers.

• 한국노년학
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• v.41 no.1
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• pp.149-168
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• 2021

This study was to develop the Medication Adherence Scale in Elderly (MAS-E) with chronic disease and verify its reliability and validity. The MAS-E was developed in 5 steps: Configuration of conceptual frame by content analysis, preliminary items, pilot study, reliability and validity test, and development of final MAS-E with chronic disease. The questionnaires were collected from 345 adults with one-to-one interviews. Verification of its reliability and validity was divided into two phases. Reliability was tested using Cronbach's alpha, split-halves reliability, and test-retest. For validity tests, item analysis, factor analysis, total score-factor score correlation analysis, and criterion related validity were used. The developed scale consisted of 18 items and 4 factors - remember of taking medication (2 items), expectations for drug effects (5 items), practice taking medication according to instructions (8 items), communicating with health professionals (3 items), and explained 69.7% of total variance. The scale had significantly positive correlation (r = .72, p <.001) with the Morisky Medication Adherence Scale (MMAS-8). Cronbach's alpha was .91, Guttman split half coefficient was .80, and test-retest reliability was .912. Finding suggest that the MAS-E is a suitable scale to assess the status of medication adherence in elderly with chronic disease.

• Journal of Korean Biological Nursing Science
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• v.5 no.2
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• pp.13-19
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• 2003

Purpose : The purpose of this study was to investigate the effects of the education using short messaging service(SMS) on fasting blood sugar(FBS) and diabetes adherence. Method : Forty-five diabetic patients being assessed pre and post intervention was used to assess the effectiveness of the education. Participants were requested to input the FBS and 2 hours post-prandial blood sugar everyday in http://www.biodang.com by cellular phone or wire Internet. The goal of the education was to lower FBS and keep diabetes adherence. The education was applied to the for 12 weeks. The education consisted of continuous education and reinforcement of diet, exercise, medication adjustment, as well as frequent self-monitoring of blood glucose levels. The education performed weekly. All medication adjustments were communicated to the participants' doctor. FBS and diabetes adherence were measured before and after the education. Results : The education using SMS of cellular phone had decrease FBS and increase oral medication taking, exercise, foot care, and hypoglycemia preparation adherence.

• Korean Journal of Clinical Pharmacy
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• v.26 no.3
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• pp.245-253
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• 2016

Objective: This study was conducted to evaluate payer-driven medication adherence intervention program from the patient's and counselor's perspectives. Methods: Target patients for intervention were selected by retrospective adherence measures based on national health insurance claims data for hypertension, diabetes and hyperlipidemia. As a serial intervention for higher risk groups of medication non-adherence, initial direct mailing, the first direct telephone call and the second direct call or a home visit were followed. Interview approach to qualitative inquiry was used to evaluate intervention results. Results: Participants including 4 patients received telephone calls, and 4 National Health Insurance Service staff and 4 pharmacists participated as counselors were interviewed regarding their impression of the intervention program. Three major themes arose: overall perception; necessities; and suggestions for success, of the intervention. Despite short period of intervention, educational intervention by telephone counseling involving pharmacists shows potential to improve self-management of chronic disease, and pharmacist-involvement. But more sophisticated selection of target patients requiring the intervention and complementation of electronic database system would be necessary. In addition, personal disposition of counselor was revealed to be an important factor for achieving successful outcome of intervention. Conclusion: The findings suggest that the individualized counseling intervention would be an efficient option for improved medication adherence. Further researches should include longer periods of interventions, a quantitative analysis using adherence measures based on claims data and consideration of clinical benefits associated with the intervention.