• Proceedings of the Korea Information Processing Society Conference
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• 2016.04a
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• pp.900-902
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• 2016

사물인터넷은 최근 몇 년간 급격한 발전을 이루었으며 발전을 바탕으로 삶의 질 향상과 상업적인 가치가 큰 스마트 환경을 구축하였다. 스마트 환경 구축을 위해서는 각각 사물들이 사용하는 통신 프로토콜 간 통신이 되어야 한다. 그러나 통신 프로토콜 간 서로 다른 통신 규약을 가지기 때문에 통신이 안 되는 이질성 문제가 있으며 이러한 문제를 해결하기 위해서는 DDS(Data Distribution Service) 기반의 어댑터(Adaptor)가 필요하다. 본 논문은 최근 각광받고 있는 BLE(Bluetooth Low Energy)를 사물 인터넷에 적용하기 위해 DDS 기반의 BLE 어댑터를 제안한다. 이러한 BLE 어댑터를 통하여 BLE와 RFID(Radio-Frequency Identification), LTE(Long-Term Evolution), 그리고 지그비(ZigBee) 등 다른 통신 프로토콜 간 이질성 문제를 해결함으로써 서로 다른 데이터를 활용할 수 있다.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.757-759
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• 2015

I use a common educational spectrographic device (SV2100R) in order to obtain astronomical spectra after inventing a new adaptor for telescopes. Experimental classes and learning projects in schools and public outreach are well established regarding imaging and photometry observations. However, experiments using astronomical spectrographs are rather hard to find because the procedures of spectral extraction and wavelength calibration is less convenient. SV2100R is a 1D CCD array and thus has the advantage of not requiring spectral extraction. In addition, basic wavelength calibration is preformed by the the provided software. It was adapted to a 12-inch reflecting telescope in the Korea Science Academy of KAIST in Busan and a spectrum of the bright object, Arcturus, was successfully obtained. This means one can provide educational programs on the topic of astronomical spectra. A few suggested projects are presented.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.17 no.10
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• pp.1081-1091
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• 1992

A new method for designing of WDF(Wave Digital Filter) is proposed, which is based on the digital dependent port adaptor transformed by the VGIC(Voltage Conversion Generalized Impedance Converter). To design the WD-LPF, WD-BPF, WD-HPF, or WD-BRF with CGIC(Current Conversion GIC). we have to use the different structure respectively. But the proposed method to design any types of WDF requires only one universal WDF structure, and this structure is attractive for its VLSI implementation for its simplicity.

• Proceedings of the KIEE Conference
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• 2005.10c
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• pp.182-185
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• 2005

This paper presents a new voltage current driven method for the synchronous rectifier (SR) in a flyback topology. The proposed synchronous rectfier of voltage-current driven can operate at wide load range with high efficiency. The gate voltage of FET in the synchronous rectifier is easily controlled by resistor ratio. regardless of line and load fluctuation. The 200W (l2V/17A) prototype is built and achiveved efficiency as high as 90% at 4A, 93.2% at 7A and full load.

• Proceedings of the Korea Information Processing Society Conference
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• 2004.05a
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• pp.233-236
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• 2004

컴포넌트 기반 소프트웨어 설계는 개발된 컴포넌트의 조립을 통한 재사용으로 소프트웨어를 생성하는 것을 목표로 하고 있다. 이때 재사용되는 컴포넌트들은 용도에 맞게 개조되어야 한다. 본 연구는 이러한 개조 방법을 트랜잭션 어뎁터(Transaction Adaptor)라는 개조 컴포넌트를 이용하여 기존의 컴포넌트 또는 기존의 레거시 시스템을 재사용하는 것에 대한 연구이다. TA를 이용한 개조방법은 클라이언트와 호스트시스템 사이에 TA컴포넌트를 사용하여, XML데이터를 스트림 형태로 변환하여 전송함으로서 레거시 시스템을 재사용한다. 이러한 TA를 이용한 재사용 방법은 클라이언트 플렛폼이나 호스트의 종류에 관계없이 TA가 XML로 데이터 변환처리하여 레거시 시스템을 재사용할 수 있다.

• Journal of the Korean Chemical Society
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• v.67 no.5
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• pp.348-352
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• 2023

p97, a universally conserved AAA+ ATPase, holds a central position in the ubiquitin-proteasome system, orchestrating myriad cellular activities with significant therapeutic implications. This protein primarily interacts with a diverse set of adaptor proteins through its N-terminal domain (NTD), which is structurally located at the periphery of the D1 hexamer ring. While there have been numerous structural elucidations of p97 complexed with adaptor proteins, the stoichiometry has remained elusive. In this work, we present the crystal structure of the p97-N/D1 hexamer bound to the FAF1-UBX domain at a resolution of 3.1 Å. Our findings reveal a 6:6 stoichiometry between the p97 hexamer and FAF1-UBX domain, deepening our understanding from preceding structural studies related to p97-NTD and UBX domain-containing proteins. These insights lay the groundwork for potential therapeutic interventions addressing cancer and neurodegenerative diseases.

• Molecules and Cells
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• v.43 no.11
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• pp.921-934
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• 2020

Lck-interacting transmembrane adaptor 1 (LIME) has been previously identified as a raft-associated transmembrane protein expressed predominantly in T and B lymphocytes. Although LIME is shown to transduce the immunoreceptor signaling and immunological synapse formation via its tyrosine phosphorylation by Lck, a Src-family kinase, the in vivo function of LIME has remained elusive in the previous studies. Here we report that LIME is preferentially expressed in effector T cells and mediates chemokine-mediated T cell migration. Interestingly, in LIME^-/- mice, while T cell receptor stimulation-dependent proliferation, differentiation to effector T cells, cytotoxic T lymphocyte (CTL) function and regulatory T lymphocyte (Treg) function were normal, only T cell-mediated inflammatory response was significantly defective. The reduced inflammation was accompanied by the impaired infiltration of leukocytes and T cells to the inflammatory sites of LIME^-/- mice. More specifically, the absence of LIME in effector T cells resulted in the reduced migration and defective morphological polarization in response to inflammatory chemokines such as CCL5 and CXCL10. Consistently, LIME^-/- effector T cells were found to be defective in chemokine-mediated activation of Rac1 and Rap1, and dysregulated phosphorylation of Pyk2 and Cas. Taken together, the present findings show that LIME is a critical regulator of inflammatory chemokine-mediated signaling and the subsequent migration of effector T cells to inflammatory sites.

• The Plant Pathology Journal
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• v.38 no.6
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• pp.593-602
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• 2022

Anthracnose, caused by the ascomycete fungus Colletotrichum scovillei, is a destructive disease in pepper. The fungus germinates and develops an infection structure called an appressorium on the plant surface. Several signaling cascades, including cAMP-mediated signaling and mitogen-activated protein kinase (MAPK) cascades, are involved in fungal development and pathogenicity in plant pathogenic fungi, but this has not been well studied in the fruit-infecting fungus C. scovillei. Ste50 is an adaptor protein interacting with multiple upstream components to activate the MAPK cascades. Here, we characterized the CsSTE50 gene of C. scovillei, a homolog of Magnaporthe oryzae MST50 that functions in MAPK cascades, by gene knockout. The knockout mutant ΔCsste50 had pleiotropic phenotypes in development and pathogenicity. Compared with the wild-type, the mutants grew faster and produced more conidia on regular agar but were more sensitive to osmotic stress. On artificial and plant surfaces, the conidia of the mutant showed significantly reduced germination and failed to form appressoria. The mutant was completely non-pathogenic on pepper fruits with or without wounds, indicating that pre-penetration and invasive growth were both defective in the mutant. Our results show that the adaptor protein CsSTE50 plays a role in vegetative growth, conidiation, germination, appressorium formation, and pathogenicity in C. scovillei.

• KIPS Transactions on Computer and Communication Systems
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• v.5 no.11
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• pp.403-410
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• 2016

IoT(Internet of Things) has purpose for providing new kind of service though interaction with everything. With development of IoT, computer model which is based on internet is changed to distributed connection model between heterogeneous things. There is a problem that it is impossible to connect between each other different protocols. To solve this problem, we should abstract each of things of data through using adaptor of middleware structure in order to make consistent data unit. In this paper, we propose BLE(Bluetooth Low Energy) adaptor, which is interaction with things, based on DDS(Data Distribution Service) that is real-time standard middleware. It is possible to data interaction between BLE Devices as well as two-way data interaction with different protocol devices. Also existing BLE Devices and study have a problem that Data exchange without using a standard data format of a profile defined by the Bluetooth SIG. Using the data formats defined independently by a problem that should not exchange data according to the type and manufacturer of the device BLE. The BLE adapter to solve this problem, the classification and analysis of the 12 stand profile was applied to create a profile based on the standard data format. It is possible to get wide interoperability of not affected on the BLE devices type and manufacturer of the device because it is applied a profile that standard data format.

• BMB Reports
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• v.49 no.12
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• pp.651-652
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• 2016

EphA2 has been implicated in amplifying ErbB2 tumorigenic signaling. One protein that interacts with EphA2 is the Anks1a PTB adaptor. However, the precise role of Anks1a in EphA2-mediated tumorigenesis is unclear. We demonstrated that Anks1a localizes to the ER upon phosphorylation and that the Ankyrin repeats and PTB of Anks1a bind to EphA2 and Sec23, respectively. Thus, Anks1a facilitates the selective packaging of EphA2 into COPII vesicles. Additionally, Anks1a knockout mice, a phenocopy of EphA2 knockout mice, exhibited markedly reduced ErbB2-induced breast tumorigenesis. Strikingly, ErbB2 did not localize to the cell surface following Anks1a knockdown in primary mammary tumor cells over-expressing ErbB2. Importantly, EphA2 was critical for stabilizing ErbB2 through complex formation, but its interaction with Anks1a also facilitated ErbB2 loading into COPII carriers. These findings suggest a novel role for Anks1a in the molecular pathogenesis of breast tumors and possibly other human diseases.