• Title/Summary/Keyword: Adaptive diversity

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Deep sequencing of B cell receptor repertoire

  • Kim, Daeun;Park, Daechan
    • BMB Reports
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    • v.52 no.9
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    • pp.540-547
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    • 2019
  • Immune repertoire is a collection of enormously diverse adaptive immune cells within an individual. As the repertoire shapes and represents immunological conditions, identification of clones and characterization of diversity are critical for understanding how to protect ourselves against various illness such as infectious diseases and cancers. Over the past several years, fast growing technologies for high throughput sequencing have facilitated rapid advancement of repertoire research, enabling us to observe the diversity of repertoire at an unprecedented level. Here, we focus on B cell receptor (BCR) repertoire and review approaches to B cell isolation and sequencing library construction. These experiments should be carefully designed according to BCR regions to be interrogated, such as heavy chain full length, complementarity determining regions, and isotypes. We also highlight preprocessing steps to remove sequencing and PCR errors with unique molecular index and bioinformatics techniques. Due to the nature of massive sequence variation in BCR, caution is warranted when interpreting repertoire diversity from error-prone sequencing data. Furthermore, we provide a summary of statistical frameworks and bioinformatics tools for clonal evolution and diversity. Finally, we discuss limitations of current BCR-seq technologies and future perspectives on advances in repertoire sequencing.

Genetic Diversity of Orobanche cumana Populations in Serbia

  • Ivanovic, Zarko;Marisavljevic, Dragana;Marinkovic, Radovan;Mitrovic, Petar;Blagojevic, Jovana;Nikolic, Ivan;Pavlovic, Danijela
    • The Plant Pathology Journal
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    • v.37 no.6
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    • pp.512-520
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    • 2021
  • In this study, we report genetic characterization of Orobanche cumana, the causal agent of sunflower wilting in Serbia. The genetic diversity of this parasitic plant in Serbia was not studied before. Random amplified polymorphic DNA (RAPD) markers and partial rbcL gene sequences analysis were used to characterize the O. cumana populations at the molecular level. While phylogenetic analyses of RAPD-PCR amplicons were performed using unweighted pair-group Method analyses, rbcL gene sequences were analyzed using neigbor joining method and minimum spanning tree. Molecular analyses of RAPD-PCR analysis revealed high genetic diversity of O. cumana populations which indicated high adaptive potential of this parasitic weed in Serbia. Further analyses of rbcL gene using minimum spanning tree revealed clear differences among diverse sections of Orobanche genus. Although this molecular marker lacked the resolution to display intrapopulation diversity it could be a useful tool for understanding the evolution of this parasitic plant. Our results suggested that O. cumana has great genetic potential which can lead to differentiation of more virulent races which is important for determining crop breeding strategies for their control.

Design and Performance Evaluation of Adaptive OFDM Communication System Robust to the Narrow-band Interference (협대역 간섭에 강한 적응형 OFDM 통신 시스템 설계와 성능 평가)

  • Jung Rag-Gyu;Kim Sun-Ae;Ryu Heung-Gyoon
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.17 no.7 s.110
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    • pp.629-637
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    • 2006
  • It is important to design the high-speed communication system in the hostile channel. Due to the frequency diversity, FD-OFDM that can be used for the high-speed communication is more robust to the noise or interference than ordinary OFDM. However, even the FD-OFDM becomes degraded in th ε strong narrow band interference channel. In this paper, we propose an AFD-OFDM system and analyze the communication performances in order to find out the more robust communication system in the hostile channel. So, the AFD-OFDM system can cover the drawback of the FD-OFDM and improve the BER performance than FD-OFDM. From the simulation results, FD-OFDM shows better performance than the ordinary OFDM. Furthermore, AFD-OFDM shows more excellent performance than FD-OFDM in the strong narrow interference channel.

Symbol Based Rate Adaptation in Coded MIMO-OFDM Systems (심볼 기반의 적응 변조 기법을 이용한 채널 부호화된 MIMO-OFDM 시스템)

  • Sung, Chang-Kyung;Kim, Ji-Hoon;Lee, In-Kyu
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.1A
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    • pp.50-58
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    • 2008
  • The use of space-division multiple access(SDMA) in the downlink of multiuser multi-input/multi-output(MIMO) wireless transmission systems can provide substantial gains in system throughput. When the channel state information(CSI) is available at the transmitter, a considerable performance improvement can be attained by adapting the transmission rates to the reported CSI. In addition, to combat frequency selective fadings in wideband wireless channels, bit-interleaved coded OFDM(BIC-OFDM) modulation schemes are employed to provide reliable packet delivery by utilizing frequency diversity through channel coding. In this paper, we propose an adaptive modulation and coding(AMC) scheme combined with an opportunistic scheduling technique for the MIMO BIC-OFDM with bandwidth-limited feedback channels. The proposed scheme enhances the link performance by exploiting both the frequency diversity and the multiuser diversity. To reduce the feedback information, the proposed AMC scheme employs rate adaptation methods based on an OFDM symbol rather than on the whole subchannels. Simulation results show that the proposed scheme exhibits a substantial performance gain with a reasonable complexity over single antenna systems.

Adaptive Control Technique for the Random Access Channel in DVB-RCS2 based Next Generation Military Satellite Networks (DVB-RCS2 기반 차세대 군 위성 네트워크 랜덤 액세스 채널 적응형 제어 기법)

  • Lee, WonKyun;Jang, Dae-Hee;Chung, Jong-Moon
    • Journal of Internet Computing and Services
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    • v.21 no.2
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    • pp.99-108
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    • 2020
  • In this paper, we analyze the most suitable RA method among PAMA, DAMA, and RA classified by the multiple access method of satellite communication in the rapidly changing traffic environment according to the emergency and tactical situation. It suggests an alternative to improve the limit of output degradation. Based on the CRDSA protocol selected as the standard of DVB-RCS2 among the current satellite communication methods, CRDSA2R (Contention) maintains an optimal RA channel environment by checking the limitations in an environment where packet volume is rapidly increasing and observing channel load and channel conditions. We propose a Resolution Diversity Slotted ALOHA with Adaptive Random Access.

Collision Avoidance Scheduling for Capacity Improvement of Adaptive OFDMA Systems (OFDMA 시스템에서 전송률 향상을 위한 충돌 회피 스케줄링)

  • Kim, Young-Ju;Song, Hyoung-Joon;Kwon, Dong-Young;Hong, Dae-Sik
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.45 no.11
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    • pp.9-14
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    • 2008
  • In this paper, we propose a collision avoidance scheduling to increase the multiuser diversity gains in the adaptive orthogonal frequency division multiple access (OFDMA) system. The scheduling policy is based on the minimum collision criterion which investigates the differences of user channels. The paper includes the derivation of capacity expressions for the adaptive OFDMA system with the proposed scheduling. The analysis shows that the capacity of the system depends on the number of collisions between the selected users to be simultaneously served. Numerical results show that the proposed scheduling provides improved capacity performance over existing ones.

A Study on Improvement of Broadband Radio Channel Characteristics using Linear Adaptive Equalizer (선형 적응 등화기 적용에 의한 광대역 무선채널 특성 개선에 관한 연구)

  • 윤영석;하덕호
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.1
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    • pp.211-218
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    • 2000
  • This paper describes the improvement of broadband radio channel characteristics using a MMSE adaptive equalization technique as a fundamental study of high transmission rates in indoor radio channel. First, the performance of 16-QAM system that employs a MMSE linear adaptive equalizer in Rayleigh fading channel is analyzed. Next, in order to improve broadband radio channel characteristics, we apply an adaptive equalization technique employing the MMSE algorithm to the radio channel measured by using circularly polarized antenna under indoor NLOS(non-line-of sight) environment. Consequently, for 16-QAM with adaptive equalizer, we can achieve the improvement of about 13 dB at $10^{-3}$ error rate as compared with general 16-QAM. Moreover, it was found that the adaptive equalization technique could improve broadband radio channel characteristics over the all measured areas. Also, it was found that the employing both adaptive equalization and polarization diversity technique together could improve broadband radio channel characteristics and reduce fading more effectively.

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Performance Analysis of an Underwater Acoustic Communication System Combining AMC and STBC Techniques

  • Jung, Jin-Woo;Shim, Tae-Bo
    • The Journal of the Acoustical Society of Korea
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    • v.26 no.3E
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    • pp.97-103
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    • 2007
  • We propose a combined STBC (Space Time Block Coding) and AMC (Adaptive Modulation and Coding) in the underwater multipath communication channel. Performance of UAC (underwater acoustic communication) in shallow water is degraded by complicated multipath and reverberation. For this reason, and considering the variability of the ocean channel, we combined STBC and AMC techniques, which are the spatial diversity in a multi-sensor communication system. BER (Bit error rate) of combined STBC and AMC is improved by 5dB when we compare with the BER of a single sensor based system. The proposed system shows a 3dB improvement when we compare it with the BER of the single sensor based system applying the AMC technique only.

DSM Hybrid Technique Using Antenna Array (배열안테나 기반의 DSM 하이브리드 방식)

  • Ryu, Kil-Hyen;Kim, Kwang-Tae
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.7
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    • pp.80-84
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    • 2010
  • A novel hybrid antenna array system for the code division multiple access (CDMA) using the diversity and beamforming technique has been proposed which is called as a dynamic selection method (DSM). Through the derived outage probability analysis, we have shown that the proposed DSM technique can give benefit over the conventional diversity-only or beamforming-only system.

Preventing Premature Convergence in Genetic Algorithms with Adaptive Population Size (유전자 집단의 크기 조절을 통한 Genetic Algorithm의 조기 포화 방지)

  • 박래정;박철훈
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.32B no.12
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    • pp.1680-1686
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    • 1995
  • GAs, effective stochastic search algorithms based on the model of natural evolution and genetics, have been successfully applied to various optimization problems. When population size is not large, GAs often suffer from the phenomenon of premature convergence in which all chromosomes in the population lose the diversity of genes before they find the optimal solution. In this paper, we propose that a new heuristic that maintains the diversity of genes by adding some chromosomes with random mutation and selective mutation into population during evolution. And population size changes dynamically with supplement of new chromosomes. Experimental results for several test functions show that when population size is rather small and the length of chromosome is not long, this method is effective.

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