• Journal of Korean Academy of Nursing
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• v.43 no.3
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• pp.431-441
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• 2013

Purpose: The study was done to explore meanings and essence of the experience in South Korea of men defectors from North Korea. Methods: Data were collected from March, 2011 to May, 2012, through in-depth interviews with ten men defectors. Data analysis was conducted using the process of hermeneutic phenomenological reflection. Results: Eight essential themes were extracted; 'buoyant expectation for a new life', 'feeling guilty about family left behind in North Korea', 'inability to become acclimatized due to communication difficulties', 'inability to socialize with South Koreans due to different lifestyles', 'finding strength through trustworthy acquaintances', 'continuing reconciliation with oneself while trying to assimilate into South Korean culture', 'self-realization of one's original self', and 'continuing to feel out the possibility of a future in South Korea'. Conclusion: The findings indicate that North Korean men who defect to South Korea shape their identity through three phases: forming self-image during escape from North Korea, trying to become accustomed to South Korean society, and finding their own identity by self-realization of their original self. Eventually, the whole process enables them to recover their identity, to feel a sense of belonging, and to discover possibilities for a better future.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.15 no.3
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• pp.387-394
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• 2008

Purpose: This study was done to identify whether the program, improving adjustment to military life would have an effect on stress, depression, idea of suicide, adjustment to military living, and self-esteem in auxiliary police. Method: This quazi experimental study using a non-equivalent control group pretest and posttest design was conducted from February 1 to May 30, 2007. Using convenience sampling, the researcher recruited 120 auxiliary police and randomly assigned each to either the experimental and the control group. The experimental group received an 8-week program to improve adjustment to military life. Results: Anxiety, stress, depression, idea of suicide, self-esteem, and adjustment to military living were significantly different between the experimental and control groups. Conclusion: These results suggest that programs to improve adjustment to military life would improve psychological health and adaptation of military living in auxiliary police. Replication studies are needed to confirm the effects of this program and to identify the long-term maintenance effects of the program.

• Journal of Korean Academy of Nursing
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• v.36 no.7
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• pp.1215-1223
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• 2006

Purpose: This study was done to understand elderly women within a community who have used lots of drugs. Method: Data was collected through in-depth interviews with four elderly women from April 2001 to February 2002. Data was analyzed by Giorgi's phenomenological method(2000). Results: The components in common with drug usage of elderly women were as follows: 'Awareness of the limitation of physical strength and uncertainty of life', 'Dread of a crisis situation occurring', 'Attachment and dependency on drugs', 'Expectation of a comfortable life and death', 'Prevention of family burden', and 'Pursuit of psychological comfort'. The general structure of experiences was as follows: causal factors were 'Awareness of uncertainty and limitation', 'dread of a crisis situation occurring' the results factor was 'Attachment and dependency on drugs' and the facilitating factors were 'Expectation of a comfortable life and death', 'Prevention of family burden', and 'Pursuit of psychological comfort'. The causal relation was cyclic. This structure showed a realistic adaptation pattern. Conclusion: This study contributed to provide fundamental data for nursing interventions for health promotion and promoting quality of life in elderly women by increasing understanding of the experiences of drugs use.

• Korean Journal of Adult Nursing
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• v.26 no.1
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• pp.58-66
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• 2014

Purpose: The aim of this study was to identify factors affecting the perception of sex life and sexual desire coping behavior among the spouseless elderly. Methods: The participants were 149 elders who resided in six administrative regions of B city. Data were collected from December 1, 2012 to March 3, 2013 using a questionnaire. Data were analyzed using descriptive statistics, t-test, ANOVA, Scheff$\acute{e}$ test, Pearson's correlation coefficient, and Stepwise multiple regression in a PASW 18.0 program. Results: Stepwise multiple regression analysis of data indicated that the most likely predictor is gender. Gender, sexual relation, subjective health status and parent-child relationship explained 34% of the variance of perception of sex life. Gender, dating status and age explained 44% of the variance of sexual desire coping behavior. Conclusion: Based on the study findings, gender and current dating status should be considered to conduct comprehensive sex health care education for healthy sex life of the elderly with no spouse.

• Journal of Society of Preventive Korean Medicine
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• v.10 no.1
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• pp.33-51
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• 2006

With the reduction of contagious diseases throughout the world and prolonged life expectancy has lead into increase of habitual related diseases. Industrial development and better economic situation made people more concerned about their health. As primary illnesses are subdued in the past years, health care system and the public value prevention and well-being more than the treatment itself. Based on this trend, this study focused on the view of life from the perspective of Oriental medicine as it's peculiarities, regimen methods, and the definition of healthy life are evaluated. Following results were obtained: - View of life in Oriental medicine focused on two basic principles of interrelationship between the organs internally, inter-dependency with the natural environment and social surrounding externally as recognition and respect between the medium were valued. - Sustaining and maintaining good health in Oriental medicine are closely related to prenatally healthy pregnancy and fetation, as well as prenatal training. Postnatal maintenance includes accommodation to seasonal changes, adequate food intake, mind control, various regimen methods and avoidance of wrong doings. - Defining health includes body's internal condition and external influences, principles of essence, qi, spirit, and yin and yang, harmony and balance, and individuality. - To conclude, good health in Oriental medicine is defined as 'external adaptation to society and natural environment, and internal balancing of individual difference with accumulation of essence, nurturing and circulating qi, and every material around the body in harmony and balance."

• Journal of Marine Life Science
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• v.6 no.2
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• pp.97-105
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• 2021

Tegillarca granosa, is one of the most important fishery resources throughout Asia. However, due to industrialization factories, marine environmental pollution, and global warming, the marine fishery production has drop sharply. In order to understand the genetic factors of the blood clam, which is a major fishery resource on the southern coast of Korea, the whole genome of blood clam was studied. The assembled genome of T. granosa was 915.4 Mb, and 19 chromosomes were identified. 25,134 genes were identified, and 22,745 genes were functionally annotated. As a result of performing gene gain and loss analysis between the blood clam genome and eight other types of shellfish, it was confirmed that 725 gene groups were expanded, and 479 gene groups were contracted. The homeobox gene cluster of blood clam showed a well-preserved genetic structure within lophotrochozoan ancestor. T. granosa genome showed high similarity between three hemoglobin genes with Scarpharca broughtonii. The blood clam genome will provide information for the genetic and physiological characteristics of blood clam adaptation, evolution, and the development of aquaculture industry.

• Asian Oncology Nursing
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• v.12 no.3
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• pp.237-245
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• 2012

Purpose: The purpose of this study was to identify attributes of the concept of cancer survivorship. Methods: Walker & Avant's concept analysis framework (2005) was used to review the medical & nursing text books, medical and nursing research articles related to cancer survivorship and published from 1985 to 2011. Results: There were nine aspects of the concept of cancer survivorship: A process, liminality, uncertainty, life-changing experience, complexity, unique experience, duality of positive and negative aspects, partnership, and need for support. Antecedents of cancer survivorship were cancer diagnosis and perception as a cancer survivor. Empirical referents of cancer survivorship were survival rate, quality of life, adaptation to the survivorship experience, and health-related hardiness, social support, spirituality, and health behavior. The consequences of cancer survivorship were effects on the physical, psychosocial, spiritual and socio-economic well-being of the patients. Conclusion: This concept analysis of cancer survivorship is expected to contribute to promotion of survivorship care in the clinical field by removing conceptual ambiguity and confirming the true meaning of survivorship care.

• Mycobiology
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• v.37 no.3
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• pp.161-170
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• 2009

Cryptococcus neoformans is a basidiomycete human fungal pathogen that causes meningoencephalitis in both immunocompromised and immunocompetent individuals. The ability to sense and respond to diverse extracellular signals is essential for the pathogen to infect and cause disease in the host. Four major stress-activated signaling (SAS) pathways have been characterized in C. neoformans, including the HOG (high osmolarity glycerol response), PKC/Mpk1 MAPK (mitogen-activated protein kinase), calcium-dependent calcineurin, and RAS signaling pathways. The HOG pathway in C. neoformans not only controls responses to diverse environmental stresses, including osmotic shock, UV irradiation, oxidative stress, heavy metal stress, antifungal drugs, toxic metabolites, and high temperature, but also regulates ergosterol biosynthesis. The PKC(protein kinase C)/Mpk1 pathway in C. neoformans is involved in a variety of stress responses, including osmotic, oxidative, and nitrosative stresses and breaches of cell wall integrity. The $Ca^{2+}$/calmodulin- and Ras-signaling pathways also play critical roles in adaptation to certain environmental stresses, such as high temperature and sexual differentiation. Perturbation of the SAS pathways not only impairs the ability of C. neoformans to resist a variety of environmental stresses during host infection, but also affects production of virulence factors, such as capsule and melanin. A drug(s) capable of targeting signaling components of the SAS pathway will be effective for treatment of cryptococcosis.

• Mycobiology
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• v.46 no.4
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• pp.361-369
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• 2018

The rice blast fungus, Magnaporthe oryzae, is an important pathogen of rice plants. It is well known that genes encoded in the genome have different evolutionary histories that are related to their functions. Phylostratigraphy is a method that correlates the evolutionary origin of genes with evolutionary transitions. Here we applied phylostratigraphy to partition total gene content of M. oryzae into distinct classes (phylostrata), which we designated PS1 to PS7, based on estimation of their emergence time. Genes in individual phylostrata did not show significant biases in their global distribution among seven chromosomes, but at the local level, clustering of genes belonging to the same phylostratum was observed. Our phylostrata-wide analysis of genes revealed that genes in the same phylostratum tend to be similar in many physical and functional characteristics such as gene length and structure, GC contents, codon adaptation index, and level of transcription, which correlates with biological functions in evolutionary context. We also found that a significant proportion of genes in the genome are orphans, for which no orthologs can be detected in the database. Among them, we narrowed down to seven orphan genes having transcriptional and translational evidences, and showed that one of them is implicated in asexual reproduction and virulence, suggesting ongoing evolution in this fungus through lineage-specific genes. Our results provide genomic basis for linking functions of pathogenicity factors and gene emergence time.

• Korean Journal of Agricultural and Forest Meteorology
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• v.17 no.1
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• pp.1-14
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• 2015

Climate change caused by elevated greenhouse gases would affect crop production through different pathways in agricultural ecosystems. Because an agricultural ecosystem has complex interactions between societal and economical environment as well as organisms, climate, and soil, adaptation measures in response to climate change on a specific sector could cause undesirable impacts on other sectors inadvertently. An integrated system, which links individual models for components of agricultural ecosystems, would allow to take into account complex interactions existing in a given agricultural ecosystem under climate change and to derive proper adaptation measures in order to improve crop productivity. Most of models for agricultural ecosystems have been used in a separate sector, e.g., prediction of water resources or crop growth. Few of those models have been desiged to be connected to other models as a module of an integrated system. Threfore, it would be crucial to redesign and to refine individual models that have been used for simulation of individual sectors. To improve models for each sector in terms of accuracy and algorithm, it would also be needed to obtain crop growth data through construction of super-sites and satellite sites for long-term monitoring of agricultural ecosystems. It would be advantageous to design a model in a sector from abstraction and inheritance of a simple model, which would facilitate development of modules compatible to the integrated prediction system. Because agricultural production is influenced by social and economical sectors considerably, construction of an integreated system that simulates agricultural production as well as economical activities including trade and demand is merited for prediction of crop production under climate change.